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    Microencapsulation of oxygen or water sensitive materials
    12.
    发明专利
    Microencapsulation of oxygen or water sensitive materials 未知

    公开(公告)号：GB2408729A

    公开(公告)日：2005-06-08

    申请号：GB0505736

    申请日：2003-09-04

    Applicant: SOUTHWEST RES INST

    Inventor： VASISHTHA NIRAJ ,  SCHLAMEUS HERMAN W ,  BARLOW DARREN E

    IPC: A23L1/00 ,  B01J13/02 ,  B01J13/04 ,  B01J13/08 ,  B01J13/10 ,  B32B5/16 ,  A23P1/04

    Abstract: A barrier coating composition includes a polymer material and a structuring agent dispersed in said polymer material, wherein the structuring agent decreases oxygen or water permeability through the polymer material. The barrier coating composition can be used to coat a core component, which can be oxygen or water sensitive, to form a microencapsulated material. The microencapsulated material can be formed by microencapsulation methods, which include atomization or coacervation methods, including forming an oil emulsion of an oil phase and an aqueous phase, the oil phase including the core component and the aqueous phase including the polymer material, adding the structuring agent to one of the oil phase and the aqueous phase, mixing the oil emulsion to form desired particle sizes of the core component, forming the shell component around the core component to form the microencapsulated material, and extracting the formed microencapsulated material from the oil emulsion.

    MICROENCAPSULATION OF OXYGEN OR WATER SENSITIVE MATERIALS
    13.
    发明专利
    MICROENCAPSULATION OF OXYGEN OR WATER SENSITIVE MATERIALS 未知

    公开(公告)号：AU2003265481A1

    公开(公告)日：2004-03-29

    申请号：AU2003265481

    申请日：2003-09-04

    Applicant: SOUTHWEST RES INST

    Inventor： VASISHTHA NIRAJ ,  SCHLAMEUS HERMAN W ,  BARLOW DARREN E

    IPC: A23L1/00 ,  B01J13/02 ,  B01J13/04 ,  B01J13/08 ,  B01J13/10 ,  B32B5/16 ,  A23P1/04

    Abstract: A barrier coating composition includes a polymer material and a structuring agent dispersed in said polymer material, wherein the structuring agent decreases oxygen or water permeability through the polymer material. The barrier coating composition can be used to coat a core component, which can be oxygen or water sensitive, to form a microencapsulated material. The microencapsulated material can be formed by microencapsulation methods, which include atomization or coacervation methods, including forming an oil emulsion of an oil phase and an aqueous phase, the oil phase including the core component and the aqueous phase including the polymer material, adding the structuring agent to one of the oil phase and the aqueous phase, mixing the oil emulsion to form desired particle sizes of the core component, forming the shell component around the core component to form the microencapsulated material, and extracting the formed microencapsulated material from the oil emulsion.

    MICROENCAPSULATION OF OXYGEN OR WATER SENSITIVE MATERIALS
    14.
    发明专利
    MICROENCAPSULATION OF OXYGEN OR WATER SENSITIVE MATERIALS 未知

    公开(公告)号：CA2499423A1

    公开(公告)日：2004-03-18

    申请号：CA2499423

    申请日：2003-09-04

    Applicant: SOUTHWEST RES INST

    Inventor： BARLOW DARREN E ,  VASISHTH NIRAJ ,  SCHLAMEUS HERMAN W

    IPC: A23L1/00 ,  B01J13/02 ,  B01J13/04 ,  B01J13/08 ,  B01J13/10 ,  B32B5/16 ,  A23P1/04

    Abstract: A barrier coating composition includes a polymer material and a structuring agent dispersed in said polymer material, wherein the structuring agent decreases oxygen or water permeability through the polymer material. The barrier coating composition can be used to coat a core component, which can be oxygen or water sensitive, to form a microencapsulated material. The microencapsulated material can be formed by microencapsulation methods, whic h include atomization or coacervation methods, including forming an oil emulsi on of an oil phase and an aqueous phase, the oil phase including the core component and the aqueous phase including the polymer material, adding the structuring agent to one of the oil phase and the aqueous phase, mixing the oil emulsion to form desired particle sizes of the core component, forming t he shell component around the core component to form the microencapsulated material, and extracting the formed microencapsulated material from the oil emulsion.

    15.
    发明专利
    未知

    公开(公告)号：BRPI0615563A2

    公开(公告)日：2011-05-24

    申请号：BRPI0615563

    申请日：2006-09-06

    Applicant: SOUTHWEST RES INST ,  SLOVIN ELIOT M

    Inventor： SLOVIN ELIOT M ,  PERSYN JOSEPH T ,  MCDONOUGH JOSEPH ,  VAIL NEAL K ,  BARLOW DARREN E ,  ZWIENER ALBERT M

    IPC: A61K47/00 ,  A61K47/30 ,  A61K47/32

    Abstract: This invention is directed to an apparatus and method for producing microparticles comprising pharmacologically active agents and biodegradable polymers. The apparatus (100) includes a spinning disk (105) containing a reservoir (708) in the center thereof and a flat inclined surface. The apparatus optionally includes serrations (712) and/or a flat surface beneath the periphery of the disk that is parallel to the rotational axis of the disk. The invention is also directed to a method for producing microparticles containing pharmacologically active agents, using the spinning disk apparatus. Formulations containing ophthalmically active agents are provided. Formulations exhibiting zero order release rates are also described.

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