公开(公告)号：AT222401T

公开(公告)日：2002-08-15

申请号：AT97910017

申请日：1997-10-08

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG W HENRY ,  MCFARLAND ERIC W ,  CONG PEIJUN ,  GUAN SHENHENG

IPC: B01J19/00 ,  C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C08F10/00 ,  C40B30/08 ,  C40B40/14 ,  C40B40/18 ,  C40B50/14 ,  C40B60/14 ,  G01H13/00 ,  G01J4/00 ,  G01N3/00 ,  G01N9/00 ,  G01N21/21 ,  G01N21/25 ,  G01N21/64 ,  G01N21/66 ,  G01N29/02 ,  G01N29/036 ,  G01N29/24 ,  G01N29/34 ,  G01N29/42 ,  G01N29/44 ,  G01N33/53 ,  G01N33/543 ,  H01J49/00 ,  H01J49/04 ,  H03H9/19

Abstract: A method of characterizing materials comprising the steps of: providing a substrate; synthesizing an array of materials on said substrate; providing at least one reactant gas wherein said reactant gas is in contact with said array of materials; activating at least one of said materials on said array with a heating source; and periodically monitoring an infrared emission from said activated material with an infrared camera, wherein said infrared camera outputs a series of signals corresponding to an emission intensity varying with time of said activated material.

公开(公告)号：AU4749397A

公开(公告)日：1998-05-05

申请号：AU4749397

申请日：1997-10-08

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG W HENRY ,  MCFARLAND ERIC W ,  CONG PEIJUN ,  GUAN SHENHENG

IPC: B01J19/00 ,  C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C08F10/00 ,  C40B30/08 ,  C40B40/14 ,  C40B40/18 ,  C40B50/14 ,  C40B60/14 ,  G01H13/00 ,  G01J4/00 ,  G01N3/00 ,  G01N9/00 ,  G01N21/21 ,  G01N21/25 ,  G01N21/64 ,  G01N21/66 ,  G01N29/02 ,  G01N29/036 ,  G01N29/24 ,  G01N29/34 ,  G01N29/42 ,  G01N29/44 ,  G01N33/53 ,  G01N33/543 ,  H01J49/00 ,  H01J49/04 ,  H03H9/19

Abstract: A method of characterizing materials comprising the steps of: providing a substrate; synthesizing an array of materials on said substrate; providing at least one reactant gas wherein said reactant gas is in contact with said array of materials; activating at least one of said materials on said array with a heating source; and periodically monitoring an infrared emission from said activated material with an infrared camera, wherein said infrared camera outputs a series of signals corresponding to an emission intensity varying with time of said activated material.

公开(公告)号：AT319988T

公开(公告)日：2006-03-15

申请号：AT97910844

申请日：1997-10-07

Applicant: SYMYX TECHNOLOGIES INC

Inventor： MCFARLAND ERIC W ,  ARCHIBALD WILLIAM

IPC: B01J19/00 ,  C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C08F10/00 ,  C40B30/08 ,  C40B40/14 ,  C40B40/18 ,  C40B50/14 ,  C40B60/14 ,  G01H13/00 ,  G01J4/00 ,  G01N3/00 ,  G01N9/00 ,  G01N21/21 ,  G01N21/25 ,  G01N21/64 ,  G01N21/66 ,  G01N29/02 ,  G01N29/036 ,  G01N29/24 ,  G01N29/34 ,  G01N29/42 ,  G01N29/44 ,  G01N33/53 ,  G01N33/543 ,  H01J49/00 ,  H01J49/04 ,  H03H9/19 ,  G01N21/35 ,  G01N25/72

Abstract: A method of characterizing materials comprising the steps of: providing a substrate; synthesizing an array of materials on said substrate; providing at least one reactant gas wherein said reactant gas is in contact with said array of materials; activating at least one of said materials on said array with a heating source; and periodically monitoring an infrared emission from said activated material with an infrared camera, wherein said infrared camera outputs a series of signals corresponding to an emission intensity varying with time of said activated material.

公开(公告)号：DE69730883T2

公开(公告)日：2005-01-27

申请号：DE69730883

申请日：1997-10-08

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG W HENRY ,  MCFARLAND ERIC W ,  CONG PEIJUN ,  GUAN SHENHENG

IPC: B01J19/00 ,  C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C08F10/00 ,  C40B30/08 ,  C40B40/14 ,  C40B40/18 ,  C40B50/14 ,  C40B60/14 ,  G01H13/00 ,  G01J4/00 ,  G01N3/00 ,  G01N9/00 ,  G01N21/21 ,  G01N21/25 ,  G01N21/64 ,  G01N21/66 ,  G01N29/02 ,  G01N29/036 ,  G01N29/24 ,  G01N29/34 ,  G01N29/42 ,  G01N29/44 ,  G01N33/53 ,  G01N33/543 ,  H01J49/00 ,  H01J49/04 ,  H03H9/19

Abstract: A method of characterizing materials comprising the steps of: providing a substrate; synthesizing an array of materials on said substrate; providing at least one reactant gas wherein said reactant gas is in contact with said array of materials; activating at least one of said materials on said array with a heating source; and periodically monitoring an infrared emission from said activated material with an infrared camera, wherein said infrared camera outputs a series of signals corresponding to an emission intensity varying with time of said activated material.

公开(公告)号：DE69730883D1

公开(公告)日：2004-10-28

申请号：DE69730883

申请日：1997-10-08

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG W HENRY ,  MCFARLAND ERIC W ,  CONG PEIJUN ,  GUAN SHENHENG

IPC: B01J19/00 ,  C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C08F10/00 ,  C40B30/08 ,  C40B40/14 ,  C40B40/18 ,  C40B50/14 ,  C40B60/14 ,  G01H13/00 ,  G01J4/00 ,  G01N3/00 ,  G01N9/00 ,  G01N21/21 ,  G01N21/25 ,  G01N21/64 ,  G01N21/66 ,  G01N29/02 ,  G01N29/036 ,  G01N29/24 ,  G01N29/34 ,  G01N29/42 ,  G01N29/44 ,  G01N33/53 ,  G01N33/543 ,  H01J49/00 ,  H01J49/04 ,  H03H9/19

Abstract: A method of characterizing materials comprising the steps of: providing a substrate; synthesizing an array of materials on said substrate; providing at least one reactant gas wherein said reactant gas is in contact with said array of materials; activating at least one of said materials on said array with a heating source; and periodically monitoring an infrared emission from said activated material with an infrared camera, wherein said infrared camera outputs a series of signals corresponding to an emission intensity varying with time of said activated material.

公开(公告)号：AU1125500A

公开(公告)日：2000-05-08

申请号：AU1125500

申请日：1999-10-19

Applicant: SYMYX TECHNOLOGIES INC

Inventor： LACY STEVEN D ,  MCFARLAND ERIC W ,  SAFIR ADAM L ,  TURNER STEPHEN J ,  ERDEN LYNN VAN ,  WANG PEI

IPC: B01J19/00 ,  C07B61/00 ,  C40B50/02 ,  C40B60/14 ,  G06F17/50 ,  G06F19/00

Abstract: A computer-implemented method for generating a library design for a combinatorial library of materials, a combinatorial library being a collection of two or more members that contain some variance in chemical composition, chemical amount, reaction conditions, and/or processing conditions, a member being a single position in a library, the method comprising: defining a set of one or more sources and one or more destinations, each source being electronic data representing a component to be used in preparing the combinatorial library and each destination being electronic data representing a conceptual arrangement of cells representing a combinatorial library, the cells corresponding to members of the combinatorial library and/or locations on a physical substrate; defining one or more mappings, the mappings in the aggregate defining a composition for each of a plurality of materials assigned to a plurality of cells in the arrangement; defining one or more parameters, each parameter being electronic data being electronic data corresponding to a process condition to be applied to one or more cells of the arrangement representing the combinatorial library; defining one or more parameter values for each of the parameters, the parameter values representing an amount of the corresponding process condition to be applied to one or more of the cells of the arrangement; and generating a data file defining the library design, the data file comprising electronic data describing the source elements, the destination elements, the mappings, the parameters and the parameter values.

公开(公告)号：CA2343534A1

公开(公告)日：2000-04-27

申请号：CA2343534

申请日：1999-10-19

Applicant: SYMYX TECHNOLOGIES INC

Inventor： MCFARLAND ERIC W ,  WANG PEI ,  SAFIR ADAM L ,  VAN ERDEN LYNN ,  TURNER STEPHEN J ,  LACY STEVEN D

IPC: G01N37/00 ,  C07B61/00 ,  C40B30/00 ,  C40B30/02 ,  C40B50/02 ,  C40B60/00 ,  G06F17/50

Abstract: Computer-implemented methods, programs and apparatus for generating a librar y design for a combinatorial library of materials. A library design includes a set of sources representing components to be used in preparing the combinatorial library, destinations representing arrangements of cells and mappings, defining one or more distribution patterns for assigning component s to cells in the destination arrangement or arrangements. Mappings include gradients and sets of user-defined equations, and are used to calculate the amount of one or more components to be assigned to a cell or cells in an arrangement. A library design can also include one or more process parameter s defined to vary over time or across a plurality of destination cells. The invention outputs a data file defining the library design, including electronic data representing the sources, the destinations and the mapping, in a format suitable for implementing manually or using automated material handling apparatus.

公开(公告)号：CA2267897A1

公开(公告)日：1998-04-16

申请号：CA2267897

申请日：1997-10-07

Applicant: SYMYX TECHNOLOGIES INC

Inventor： ARCHIBALD WILLIAM ,  MCFARLAND ERIC W

IPC: B01J19/00 ,  C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C08F10/00 ,  C40B30/08 ,  C40B40/14 ,  C40B40/18 ,  C40B50/14 ,  C40B60/14 ,  G01H13/00 ,  G01J4/00 ,  G01N3/00 ,  G01N9/00 ,  G01N21/21 ,  G01N21/25 ,  G01N21/64 ,  G01N21/66 ,  G01N29/02 ,  G01N29/036 ,  G01N29/24 ,  G01N29/34 ,  G01N29/42 ,  G01N29/44 ,  G01N33/53 ,  G01N33/543 ,  H01J49/00 ,  H01J49/04 ,  H03H9/19 ,  G01N21/35 ,  G01N25/18 ,  G01N21/63 ,  G01N21/75

Abstract: Methods and apparatus for screening diverse arrays of materials using infrared imaging techniques are provided. Typically, each of the individual materials on the array will be screened or interrogated for the same material characteristic. Once screened, the individual materials may be ranked or otherwise compared relative to each other with respect to the material characteristic under investigation. According to one aspect, infrared imaging techniques are used to identify the active sites within an array of compounds by monitoring the temperature change resulting from a reaction. This same technique can also be used to quantify the stability of each new material within an array of compounds. According to another aspect, identification and characterization of condensed phase products is achieved, wherein library elements are activated by a heat source serially, or in parallel. According to another aspect, a Fourier transform infrared spectrometer is used to rapidly characterize a large number of chemical reactions contained within a combinatorial library.

公开(公告)号：WO0023921A9

公开(公告)日：2000-11-16

申请号：PCT/US9924491

申请日：1999-10-19

Applicant: SYMYX TECHNOLOGIES INC

Inventor： LACY STEVEN D ,  MCFARLAND ERIC W ,  SAFIR ADAM L ,  TURNER STEPHEN J ,  VAN ERDEN LYNN ,  WANG PEI

IPC: B01J19/00 ,  C07B61/00 ,  C40B50/02 ,  C40B60/14 ,  G06F17/50 ,  G06F19/00

CPC classification number: C40B50/02 ,  B01J19/0046 ,  B01J2219/00477 ,  B01J2219/00479 ,  B01J2219/00495 ,  B01J2219/00689 ,  B01J2219/00695 ,  B01J2219/00698 ,  B01J2219/007 ,  C40B60/14

Abstract: Computer-implemented methods, programs and apparatus for generating a library design for a combinatorial library of materials. A library design includes a set of sources representing components to be used in preparing the combinatorial library, destinations representing arrangements of cells and mappings, defining one or more distribution patterns for assigning components to cells in the destination arrangement or arrangements. Mappings include gradients and sets of user-defined equations, and are used to calculate the amount of one or more components to be assigned to a cell or cells in an arrangement. A library design can also include one or more process parameters defined to vary over time or across a plurality of destination cells. The invention outputs a data file defining the library design, including electronic data representing the sources, the destinations and the mapping, in a format suitable for implementing manually or using automated material handling apparatus.

Abstract translation: 用于为材料组合库生成库设计的计算机实现的方法，程序和装置。 库设计包括一组表示用于准备组合库的组件的源，代表单元和映射的布置的目的地，定义用于将组件分配给目的地布置中的单元的一个或多个分布模式。 映射包括梯度和用户定义的方程组，用于计算一个或多个要分配给一个或多个单元的组件的数量。 库设计还可以包括定义为随着时间或跨多个目标单元而变化的一个或多个过程参数。 本发明输出定义库设计的数据文件，该文件包括表示源，目的地和映射的电子数据，其格式适合手动实现或使用自动化材料处理装置。