公开(公告)号：AU4812097A

公开(公告)日：1998-05-05

申请号：AU4812097

申请日：1997-10-07

Applicant: SYMYX TECHNOLOGIES INC

Inventor： MCFARLAND ERIC W ,  ARCHIBALD WILLIAM

IPC: B01J19/00 ,  C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C08F10/00 ,  C40B30/08 ,  C40B40/14 ,  C40B40/18 ,  C40B50/14 ,  C40B60/14 ,  G01H13/00 ,  G01J4/00 ,  G01N3/00 ,  G01N9/00 ,  G01N21/21 ,  G01N21/25 ,  G01N21/64 ,  G01N21/66 ,  G01N29/02 ,  G01N29/036 ,  G01N29/24 ,  G01N29/34 ,  G01N29/42 ,  G01N29/44 ,  G01N33/53 ,  G01N33/543 ,  H01J49/00 ,  H01J49/04 ,  H03H9/19 ,  G01N21/35 ,  G01N25/72

Abstract: A method of characterizing materials comprising the steps of: providing a substrate; synthesizing an array of materials on said substrate; providing at least one reactant gas wherein said reactant gas is in contact with said array of materials; activating at least one of said materials on said array with a heating source; and periodically monitoring an infrared emission from said activated material with an infrared camera, wherein said infrared camera outputs a series of signals corresponding to an emission intensity varying with time of said activated material.

公开(公告)号：CA2267897C

公开(公告)日：2005-12-06

申请号：CA2267897

申请日：1997-10-07

Applicant: SYMYX TECHNOLOGIES INC

Inventor： MCFARLAND ERIC W ,  ARCHIBALD WILLIAM

IPC: B01J19/00 ,  C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C08F10/00 ,  C40B30/08 ,  C40B40/14 ,  C40B40/18 ,  C40B50/14 ,  C40B60/14 ,  G01H13/00 ,  G01J4/00 ,  G01N3/00 ,  G01N9/00 ,  G01N21/21 ,  G01N21/25 ,  G01N21/64 ,  G01N21/66 ,  G01N29/02 ,  G01N29/036 ,  G01N29/24 ,  G01N29/34 ,  G01N29/42 ,  G01N29/44 ,  G01N33/53 ,  G01N33/543 ,  H01J49/00 ,  H01J49/04 ,  H03H9/19 ,  G01N21/35 ,  G01N25/18 ,  G01N33/483 ,  G01N21/63 ,  G01N21/75

Abstract: Methods and apparatus for screening diverse arrays of materials using infrared imaging techniques are provided. Typically, each of the individual materials on the array will be screened or interrogated for the same material characteristic. Once screened, the individual materials may be ranked or otherwise compared relative to each other with respect to the material characteristic under investigation. According to one aspect, infrared imaging techniques are used to identify the active sites within an array of compounds by monitoring the temperature change resulting from a reaction. This same technique can also be used to quantify the stability of each new material within an array of compounds. According to another aspect, identification and characterization of condensed phase products is achieved, wherein library elements are activated by a heat source serially, or in parallel. According to another aspect, a Fourier transform infrared spectrometer is used to rapidly characterize a large number of chemical reactions contained within a combinatorial library.

公开(公告)号：DE69735411T2

公开(公告)日：2006-09-07

申请号：DE69735411

申请日：1997-10-07

Applicant: SYMYX TECHNOLOGIES INC

Inventor： MCFARLAND W ,  ARCHIBALD WILLIAM

IPC: G01N21/35 ,  B01J19/00 ,  C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C08F10/00 ,  C40B30/08 ,  C40B40/14 ,  C40B40/18 ,  C40B50/14 ,  C40B60/14 ,  G01H13/00 ,  G01J4/00 ,  G01N3/00 ,  G01N9/00 ,  G01N21/21 ,  G01N21/25 ,  G01N21/64 ,  G01N21/66 ,  G01N25/72 ,  G01N29/02 ,  G01N29/036 ,  G01N29/24 ,  G01N29/34 ,  G01N29/42 ,  G01N29/44 ,  G01N33/53 ,  G01N33/543 ,  H01J49/00 ,  H01J49/04 ,  H03H9/19

Abstract: A method of characterizing materials comprising the steps of: providing a substrate; synthesizing an array of materials on said substrate; providing at least one reactant gas wherein said reactant gas is in contact with said array of materials; activating at least one of said materials on said array with a heating source; and periodically monitoring an infrared emission from said activated material with an infrared camera, wherein said infrared camera outputs a series of signals corresponding to an emission intensity varying with time of said activated material.

公开(公告)号：AU4902497A

公开(公告)日：1998-05-05

申请号：AU4902497

申请日：1997-10-08

Applicant: SYMYX TECHNOLOGIES INC

Inventor： MCFARLAND ERIC W ,  DANIELSON EARL ,  ARCHIBALD WILLIAM

IPC: B01J19/00 ,  C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C08F10/00 ,  C40B30/08 ,  C40B40/14 ,  C40B40/18 ,  C40B50/14 ,  C40B60/14 ,  G01H13/00 ,  G01J4/00 ,  G01N3/00 ,  G01N9/00 ,  G01N21/21 ,  G01N21/25 ,  G01N21/64 ,  G01N21/66 ,  G01N29/02 ,  G01N29/036 ,  G01N29/24 ,  G01N29/34 ,  G01N29/42 ,  G01N29/44 ,  G01N33/53 ,  G01N33/543 ,  H01J49/00 ,  H01J49/04 ,  H03H9/19 ,  G03C5/00 ,  F16K31/143

Abstract: A method of characterizing materials comprising the steps of: providing a substrate; synthesizing an array of materials on said substrate; providing at least one reactant gas wherein said reactant gas is in contact with said array of materials; activating at least one of said materials on said array with a heating source; and periodically monitoring an infrared emission from said activated material with an infrared camera, wherein said infrared camera outputs a series of signals corresponding to an emission intensity varying with time of said activated material.

公开(公告)号：DE69735411D1

公开(公告)日：2006-05-04

申请号：DE69735411

申请日：1997-10-07

Applicant: SYMYX TECHNOLOGIES INC

Inventor： MCFARLAND W ,  ARCHIBALD WILLIAM

IPC: G01N21/35 ,  B01J19/00 ,  C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C08F10/00 ,  C40B30/08 ,  C40B40/14 ,  C40B40/18 ,  C40B50/14 ,  C40B60/14 ,  G01H13/00 ,  G01J4/00 ,  G01N3/00 ,  G01N9/00 ,  G01N21/21 ,  G01N21/25 ,  G01N21/64 ,  G01N21/66 ,  G01N25/72 ,  G01N29/02 ,  G01N29/036 ,  G01N29/24 ,  G01N29/34 ,  G01N29/42 ,  G01N29/44 ,  G01N33/53 ,  G01N33/543 ,  H01J49/00 ,  H01J49/04 ,  H03H9/19

Abstract: A method of characterizing materials comprising the steps of: providing a substrate; synthesizing an array of materials on said substrate; providing at least one reactant gas wherein said reactant gas is in contact with said array of materials; activating at least one of said materials on said array with a heating source; and periodically monitoring an infrared emission from said activated material with an infrared camera, wherein said infrared camera outputs a series of signals corresponding to an emission intensity varying with time of said activated material.

公开(公告)号：AT319988T

公开(公告)日：2006-03-15

申请号：AT97910844

申请日：1997-10-07

Applicant: SYMYX TECHNOLOGIES INC

Inventor： MCFARLAND ERIC W ,  ARCHIBALD WILLIAM

IPC: B01J19/00 ,  C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C08F10/00 ,  C40B30/08 ,  C40B40/14 ,  C40B40/18 ,  C40B50/14 ,  C40B60/14 ,  G01H13/00 ,  G01J4/00 ,  G01N3/00 ,  G01N9/00 ,  G01N21/21 ,  G01N21/25 ,  G01N21/64 ,  G01N21/66 ,  G01N29/02 ,  G01N29/036 ,  G01N29/24 ,  G01N29/34 ,  G01N29/42 ,  G01N29/44 ,  G01N33/53 ,  G01N33/543 ,  H01J49/00 ,  H01J49/04 ,  H03H9/19 ,  G01N21/35 ,  G01N25/72

Abstract: A method of characterizing materials comprising the steps of: providing a substrate; synthesizing an array of materials on said substrate; providing at least one reactant gas wherein said reactant gas is in contact with said array of materials; activating at least one of said materials on said array with a heating source; and periodically monitoring an infrared emission from said activated material with an infrared camera, wherein said infrared camera outputs a series of signals corresponding to an emission intensity varying with time of said activated material.

公开(公告)号：CA2267897A1

公开(公告)日：1998-04-16

申请号：CA2267897

申请日：1997-10-07

Applicant: SYMYX TECHNOLOGIES INC

Inventor： ARCHIBALD WILLIAM ,  MCFARLAND ERIC W

IPC: B01J19/00 ,  C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C08F10/00 ,  C40B30/08 ,  C40B40/14 ,  C40B40/18 ,  C40B50/14 ,  C40B60/14 ,  G01H13/00 ,  G01J4/00 ,  G01N3/00 ,  G01N9/00 ,  G01N21/21 ,  G01N21/25 ,  G01N21/64 ,  G01N21/66 ,  G01N29/02 ,  G01N29/036 ,  G01N29/24 ,  G01N29/34 ,  G01N29/42 ,  G01N29/44 ,  G01N33/53 ,  G01N33/543 ,  H01J49/00 ,  H01J49/04 ,  H03H9/19 ,  G01N21/35 ,  G01N25/18 ,  G01N21/63 ,  G01N21/75

Abstract: Methods and apparatus for screening diverse arrays of materials using infrared imaging techniques are provided. Typically, each of the individual materials on the array will be screened or interrogated for the same material characteristic. Once screened, the individual materials may be ranked or otherwise compared relative to each other with respect to the material characteristic under investigation. According to one aspect, infrared imaging techniques are used to identify the active sites within an array of compounds by monitoring the temperature change resulting from a reaction. This same technique can also be used to quantify the stability of each new material within an array of compounds. According to another aspect, identification and characterization of condensed phase products is achieved, wherein library elements are activated by a heat source serially, or in parallel. According to another aspect, a Fourier transform infrared spectrometer is used to rapidly characterize a large number of chemical reactions contained within a combinatorial library.