公开(公告)号：JPS60143765A

公开(公告)日：1985-07-30

申请号：JP24980983

申请日：1983-12-29

Applicant: SHIMADZU CORP

Inventor： MITO YASUTAKA

IPC: G01N30/86 ,  G01J3/28 ,  G01N21/27 ,  G01N30/78

Abstract: PURPOSE:To make features of a sample easy to distinguish by indicating the height or area at each peak corresponding to the emerging time thereof and the angle vector computed in a pair of coordinate data. CONSTITUTION:A sample is made to flow to a flowcell F from a liquid chromatograph LC, analyzed with a spectroscope 3 being exposed to light from a light source 2 and the results are inputted into a photodiode array 4. Outputs of photodiodes 4 are inputted into a memory 7 at a specified time interval. An arithmetic processing circuit 8 computes the height or area at peaks from absorbance-time characteristic at a specified wavelength when each peak emerge. The angle in individual absorbance corresponding to the specified wavelength is computed from the vector thereof. Then, the angle and area are shown on a display 12 when each peak appears. For example, data of absorbance-wavelength- time is processed to be converted into an image in a three-dimensional manner as shown in the drawing B. Thus, separated components of the chromatograph can be patternized by qualitative and quantitative combination thereby facilitating the extraction of features of the sample.

公开(公告)号：JP2013171014A

公开(公告)日：2013-09-02

申请号：JP2012037044

申请日：2012-02-23

Applicant: Shimadzu Corp ,  株式会社島津製作所

Inventor： MITO YASUTAKA

IPC: G01N30/86 ,  G01N30/74

Abstract: PROBLEM TO BE SOLVED: To provide a data processing device for a chromatograph and a data processing method for a chromatograph, which can highly accurately determine whether a peak includes impurities or not without requiring a complicated calculation processing.SOLUTION: In a data processing device 2 for a chromatograph which relates to the present invention, a wavelength chromatogram creation part 22 creates a wavelength chromatogram regarding a plurality of absorption wavelengths of a target component about sample three-dimensional data acquired by measuring a sample. A peak retention time acquisition part 23 acquires a peak retention time of the peak apex of a target peak in the wavelength chromatogram. A peak retention time difference calculation part 24 calculates the difference between the maximum peak retention time and the minimum peak retention time of the plurality of acquired peak retention times. A determination part 25 determines the purity of the target peak by comparing the difference with a predetermined determination value.

Abstract translation: 要解决的问题：提供用于色谱仪的数据处理装置和用于色谱仪的数据处理方法，其可以高精度地确定峰是否包括杂质，而不需要复杂的计算处理。解决方案：在数据处理装置2 对于与本发明有关的色谱仪，波长色谱图生成部分22产生关于通过测量样品获取的样品三维数据的关于目标成分的多个吸收波长的波长色谱图。 峰保留时间获取部23获取波长色谱图中的目标峰的峰顶的峰保留时间。 峰值保持时间差计算部24计算多个获取的峰值保持时间的最大峰值保持时间和最小峰值保持时间之间的差。 确定部25通过将该差与预定的确定值进行比较来确定目标峰的纯度。

公开(公告)号：JP2011185743A

公开(公告)日：2011-09-22

申请号：JP2010051299

申请日：2010-03-09

Applicant: Shimadzu Corp ,  株式会社島津製作所

Inventor： MITO YASUTAKA

IPC: G01N30/86 ,  G01N30/74

Abstract: PROBLEM TO BE SOLVED: To provide a chromatogram peak purity determination apparatus for accurately determining a peak purity at a high concentration.
SOLUTION: The three-dimensional chromatogram peak purity determination apparatus for a retention time, a wavelength and the absorbance comprises: an absorbance accumulation means 71 for accumulating the absorbance in the entire or partial wavelength range for a predetermined retention time range at a retention time in the wavelength direction; an equal absorbance accumulation value group extracting means 73 for extracting a plurality of groups including one point on a rising slope and one point on a falling slope on which absorbance accumulation values are equal with regard to a peak of a two-dimensional chromatogram of the absorbance accumulation value and the retention time; a similarity calculation means 74 for calculating the similarity between absorption spectrum at one point on the rising slope and absorption spectrum at one point on the falling slope in each extracted group; and a determination means 76 for determining whether the peak is a single component from the similarity calculated by a plurality of the extracted groups. Since the spectrum similarity between the high concentration and the low concentration is not compared, an effect for degrading the linearity at the high concentration does not impact. The peak purity can be accurately determined at the high concentration.
COPYRIGHT: (C)2011,JPO&INPIT

Abstract translation: 要解决的问题：提供用于精确地确定高浓度的峰纯度的色谱峰纯度测定装置。 解决方案：保留时间，波长和吸光度的三维色谱峰纯度测定装置包括：吸光度累积装置71，用于在预定的保留时间范围内将吸光度在整个或部分波长范围内积累， 在波长方向的保留时间; 相等的吸光度积累值组提取装置73，用于提取包括吸光度累积值相对于吸光度积分值的二维色谱图的峰值的上升斜坡上的一个点和下降斜率上的一个点的多个组 积累值和保留时间; 相似度计算装置74，用于计算每个提取组中的上升斜率上的一个点的吸收光谱与下降斜率上的一个点处的吸收光谱之间的相似度; 以及确定装置76，用于根据由多个提取的组计算的相似度来确定峰值是否是单个分量。 由于没有比较高浓度和低浓度之间的光谱相似性，所以在高浓度下降低线性的效果不会受到影响。 峰值纯度可以在高浓度下精确测定。 版权所有（C）2011，JPO＆INPIT

公开(公告)号：JP2011170420A

公开(公告)日：2011-09-01

申请号：JP2010031165

申请日：2010-02-16

Applicant: Shimadzu Corp ,  株式会社島津製作所

Inventor： MITO YASUTAKA ,  ISHIBASHI ISAO

IPC: G06F17/30 ,  G06F12/00

CPC classification number: G06F17/30011

Abstract: PROBLEM TO BE SOLVED: To browse and specify a document from a point of view requested by a user in case of storing a document in a folder, and tree-displaying the folder in a document management system to be used for activating various data (document) as intellectual asset in a research facility or the like.
SOLUTION: A user is made to assign classifications described in a preliminarily prepared master file to any of hierarchies whose number corresponds to the number of classifications. Then, on the basis of the classification of each of the selected hierarchies, corresponding folders and documents are displayed by a tree format. Thus, it is possible to freely change a hierarchical structure which is used to be fixed in a conventional manner.
COPYRIGHT: (C)2011,JPO&INPIT

Abstract translation: 要解决的问题：为了在将文档存储在文件夹中的情况下从用户要求的角度浏览和指定文档，并且在文档管理系统中树形显示用于激活各种文件的文件夹 数据（文档）作为研究设施中的智力资产等。 解决方案：使用户将预先准备好的主文件中描述的分类分配给其数量对应于分类数量的任何层次结构。 然后，根据所选择的各层次的分类，通过树形式显示对应的文件夹和文档。 因此，可以自由地改变以常规方式固定的层次结构。 版权所有（C）2011，JPO＆INPIT

公开(公告)号：JPH0792152A

公开(公告)日：1995-04-07

申请号：JP23816693

申请日：1993-09-24

Applicant: SHIMADZU CORP

Inventor： MITO YASUTAKA

IPC: G01N30/86

Abstract: PURPOSE:To make it possible to accurately identify other peak even if the holding time of reference peak fluctuates by employing some peak extraction means and determining relevant peaks for all extracting means being employed. CONSTITUTION:A standard holding time tR and an allowance DELTAtR are set for a reference peak and then a standard value and an allowable width are set for the area of standard peak. Similarly, an allowance SR of analogy is set between the spectrum of reference peak and a standard spectrum. Upon finishing the setting, analysis is started with chromatograph. Upon finishing the analysis, peaks Pi within the set allowance are picked up. Subsequently, peaks Pi within the set allowance of peak area are picked up and the spectral analogy Si of the peak Pi with the reference peak is determined thus determining the peak PK satisfying the relationship Si>SR. When more than one PK is present, the remaining peak PK is employed as a reference peak in the calculation of other relative holding time thus indentifying other peak.

公开(公告)号：JPH04130270A

公开(公告)日：1992-05-01

申请号：JP25357490

申请日：1990-09-20

Applicant: SHIMADZU CORP

Inventor： MITO YASUTAKA ,  NAKAGAWA KATSUHIRO

IPC: G01N30/86

Abstract: PURPOSE:To automatically set the change tolerant width of the holding time of the peak of an objective component by calculating the mean value and standard deviation of the holding times of the peak of the objective component from a plurality of chromatograms obtained from the same standard sample. CONSTITUTION:At first, a necessary amount of a standard sample is analyzed and chromatogram data are stored in a memory and the stored chromatogram data are allowed to load to be displayed on a CRT 14 and the peak of an objective component is designated using a cursor on the CRT 14. The mean value X and standard deviation sigma of the holding times are calculated from a plurality of data with respect to the designated peak by a CPU 8. From the calculated values, a holding time X+nsigma (n is coefficient, for example, 3 and nsigma is change tolerant width) is automatically set as the identified parameter of the objective component. Next, an unknown sample is measured. From the chromatogram of the analytical result of the unknown sample, the peak nearest to the mean value X within the range of X+nsigma is identified as the objective component by the CPU 8 and the quantifying calculation of the peak is also carried out.

公开(公告)号：JPH01161123A

公开(公告)日：1989-06-23

申请号：JP31967587

申请日：1987-12-16

Applicant: SHIMADZU CORP

Inventor： MITO YASUTAKA

IPC: G01J3/28 ,  G01J3/42 ,  G01N21/27 ,  G01N23/00 ,  G01N29/00 ,  G01N30/86

Abstract: PURPOSE:To securely judge the reliability of measurement by using at least two similar spectrum patterns and calculating a criterion from a specific equation. CONSTITUTION:A noise vector n which contains a noise component detected by a detector at the time of relative intensity group detection as an element is set previously, and this noise vector n and two similar spectrum vectors s1 and s2 are used to find the criterion (t) from the equation. Then when he influence of noise vectors contained at the time of detecting a cosine value (r) determined by the vectors s1 and s2 with respect to the vectors s1 and s2 is considered at a maximum, the value (r) is compared with the cosine value (t) of a maximum permissible included angle and when r>=t, it is decided that the two spectrum patterns conform with each other. Thus, the limit of the discrimination of the consistency between similar spectrums can be represented numerically, so the reliability of measurement is securely judged.

公开(公告)号：JPS62167422A

公开(公告)日：1987-07-23

申请号：JP27046685

申请日：1985-11-30

Applicant: SHIMADZU CORP

Inventor： IWASAKI HIDEO ,  MITO YASUTAKA

IPC: G01N21/01 ,  G01J3/28 ,  G01J3/42

Abstract: PURPOSE:To efficiently prevent the generation of the error of a detection value based on the variation in the dark signal of a photodiode array (FDA) or that in the brightness of a light source, by thermostatically holding FDA to stabilize the dark signal. CONSTITUTION:At first, because FDA and a diode 7 are mounted in the same thermostatic container 8, both of them are respectively held to a constant temp. of 30 deg.C. When an irradiation light path is closed by a blocking plate 61, the outputs, that is, the dark signals of 501 respective elements of FDA5 are detected and subjected to A/D conversion by an A/D converter 92 to be stored in a calculation part 93. Subsequently, when the light path is opened by the blocking plate 61, irradiated light is transmitted through a flow cell 2 to be spectrally diffracted by a diffraction lattice 4 and detected by FDA5 and a part thereof is detected by the diode 71. In this case, the outputs of 501 elements at the point of time (t) are respectively stored in the memory of the calculation part 93 and, at the same time, the intensity of irradiated light is detected by the diode 71 to be stored similarly. These data are calculated on the basis of a predetermined formula and the absorbancy of a specimen at the detection time (t) is calculated for each wavelength.

公开(公告)号：JPS6218008B2

公开(公告)日：1987-04-21

申请号：JP2599681

申请日：1981-02-23

Applicant: SHIMADZU CORP

Inventor： MITO YASUTAKA ,  IWASAKI HIDEO

IPC: G01N21/27 ,  G01J3/42 ,  G01N30/74

公开(公告)号：JPH04326058A

公开(公告)日：1992-11-16

申请号：JP12468291

申请日：1991-04-25

Applicant: SHIMADZU CORP

Inventor： MITO YASUTAKA

IPC: B01D15/08 ,  G01N30/80 ,  G01N30/86

Abstract: PURPOSE:To certainly sample an objective component regardless of a condition such as a holding time or peak sequence by preliminarily storing the spectrum data of a component to be sampled and comparing the same with the spectrum data of an analyzed outflow component. CONSTITUTION:After a mobile phase is sent to a column 1 and a sample is injected in a sample injection part 8, the absorption spectrum data of the eluate of the column 1 is read in a buffer memory MB. A comparing operation part C performs the comparing operation of said data and the adsorption spectrum data of an objective component stored in a reference data memory MS. The calculated value of the degree of coincidence is compared with the judging level stored in a judging level memory part J and, based on whether said value is larger than the judging level, a three-way valve 3 is changed over to a sampling container 4 or a drainage receiver 5. As mentioned above, since the outflow component of a chromatograph and the objected component are identified and the outflow component regarded as a substance of the same kind is sampled, the objective component can be certainly sampled even when a holding time is shifted or the peak of impurity appears on the way.