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    1,3-bis-(N-lactamyl) propane and the pharmaceutical and cosmetic use thereof
    11.
    发明授权
    1,3-bis-(N-lactamyl) propane and the pharmaceutical and cosmetic use thereof 有权
    1,3-二 - （N-内酰胺基）丙烷及其药物和化妆品用途

    公开(公告)号：US06497886B1

    公开(公告)日：2002-12-24

    申请号：US09269780

    申请日：1999-04-01

    Applicant: Jörg Breitenbach ,  Siegfried Lang ,  Detlef Kratz

    Inventor： Jörg Breitenbach ,  Siegfried Lang ,  Detlef Kratz

    IPC: A61K4722

    CPC classification number: A61K9/0014 ,  A61K8/49 ,  A61K8/4906 ,  A61K8/4913 ,  A61K8/4926 ,  A61K9/0019 ,  A61K47/22 ,  A61Q19/00 ,  C07D207/267 ,  C07D211/40

    Abstract: The present invention relates to a 1,3-bis-(N-lactamyl)propane of general formula (I), wherein radicals R1, R2, R3, R4, R5 and R6 independently stand for hydrogen, alkyl, cycloalkyl, aryl or aralkyl and at least one of said radicals does not stand for hydrogen, (NLac) and (NLac′) are the same or different and stand for N-lactamyl radicals. The invention also relates to the use of said substances as a solvent in pharmaceutical and cosmetic agents. Disclosed are novel compounds of formula (I), wherein R1 and methyl and R2-R6 stand for hydrogen.

    Abstract translation: 本发明涉及通式（I）的1,3-双 - （N-内酰胺基）丙烷，其中基团R 1，R 2，R 3，R 4，R 5和R 6独立代表氢，烷基，环烷基，芳基或芳烷基 并且所述基团中的至少一个不代表氢，（NLac）和（NLac'）相同或不同，代表N-内酰胺基。 本发明还涉及所述物质作为药物和化妆品中的溶剂的用途。 公开了式（I）的新化合物，其中R1和甲基和R2-R6代表氢。

    Direct tableting auxiliary
    15.
    发明授权
    Direct tableting auxiliary 失效
    直接压片辅助

    公开(公告)号：US5006345A

    公开(公告)日：1991-04-09

    申请号：US284765

    申请日：1988-12-12

    Applicant: Siegfried Lang

    Inventor： Siegfried Lang

    IPC: A61K9/20 ,  A61K47/00

    CPC classification number: A61K9/2027 ,  A61K9/2018 ,  A61K9/2095

    Abstract: Direct tableting auxiliaries essentially consists of(A) from 88 to 96% by weight of pulverulent carrier conventionally used for the preparation of tablets and consisting of lactose, or lactose together with not more than the same amount of another carrier,(B) from 2 to 6% by weight of polyvinylpyrrolidone having a K value of from 20 to 40, and(C) from 2 to 10% by weight of crosslinked, insoluble polyvinylpyrrolidone, all percentages being based on the direct tableting auxiliary, and are obtained by spray drying, spray granulation or wet granulation.The novel direct tableting auxiliaries exhibit good flow and good compressibility under low pressure, and the tablets produced using the said auxiliaries possess excellent disintegration properties coupled with great hardness and low abrasion.

    Abstract translation: 直接压片助剂基本上由（A）88至96重量％的常规用于制备片剂的粉状载体，由乳糖或乳糖以及不超过相同量的另一种载体组成的（B）2 至6重量％的K值为20至40的聚乙烯吡咯烷酮，和（C）2至10重量％的交联的不溶性聚乙烯吡咯烷酮，所有百分比基于直接压片助剂，并通过喷雾干燥 ，喷雾造粒或湿法制粒。 新型直接压片助剂在低压下表现出良好的流动性和良好的压缩性，并且使用所述助剂制备的片剂具有优异的崩解性能，同时具有极好的硬度和低的磨损性。

    Infrared radiation process for a high contrast in the natural grain of a naturally pale wood
    18.
    发明授权
    Infrared radiation process for a high contrast in the natural grain of a naturally pale wood 失效
    在天然木材中的高对比度的红外辐射过程

    公开(公告)号：US5190791A

    公开(公告)日：1993-03-02

    申请号：US779253

    申请日：1991-10-18

    Applicant: Jurgen Gunter ,  Siegfried Kohler ,  Siegfried Lang ,  Luise Schellhorn ,  Erwin Lutz

    Inventor： Jurgen Gunter ,  Siegfried Kohler ,  Siegfried Lang ,  Luise Schellhorn ,  Erwin Lutz

    IPC: B27K5/00 ,  B27M1/06 ,  B44C1/00

    CPC classification number: B27K5/001 ,  B27K5/005 ,  B27M1/06 ,  B44C1/005 ,  B27K5/003

    Abstract: A process brings out a high contrast in natural grain of a naturally pale wood via infrared irradiation having a wavelength which is as long as possible. This infrared radiation can come from a conventional infrared emitter or, more preferably, from a carbon dioxide laser. Due to the contact-free heating near the surface which is effective in a stagnant ambient atmosphere, the new wood part of the grain is browned, while the harder old wood part remains essentially unbrowned. This causes the natural grain of the wood to stand out in contrast. Due to the contact-free and turbulence-free mode of operation of the heating, the grain pattern produced is uniform. Any scratches or chatter marks in the wood are simply covered over and remain invisible.

    Abstract translation: 一个过程通过具有尽可能长的波长的红外辐射，在天然的木材天然颗粒中产生高对比度。 该红外辐射可以来自常规的红外发射器，或者更优选地来自二氧化碳激光器。 由于表面附近的无接触加热，在停滞的环境气氛中有效，所以谷物的新木材部分变褐，而较硬的旧木材部分基本上保持不变。 相比之下，这使得木材的天然颗粒脱颖而出。 由于无接触和无湍流的加热操作模式，产生的颗粒图案是均匀的。 木头上任何划痕或颤抖的痕迹都被覆盖并保持隐形。

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