Abstract:
3-Amino-3-arylpropionic acid n-alkyl esters represented by the general formula (I); a process for the production of the same; and optical isomers thereof: (I) [wherein Ar1 is optionally substituted aryl exclusive of phenyl and 4-methoxyphenyl; and R1 is n-propyl or n-butyl], and a process for the production of optically active (S or R)-3-amino-3-arylpropininc acids represented by the general formula (III-a): (III-a) [wherein Ar is optionally substituted aryl; and * is an asymmetric carbon] and optically active (R or S)-3-amino-3-arylpropionic acid n-alkyl esters represented by the general formula (IV-a): (IV-a) [wherein Ar, R1 and * are each as defined above, with the proviso that each ester has an absolute configuration opposite to that of the compound (III-a)].