公开(公告)号：AT528648T

公开(公告)日：2011-10-15

申请号：AT03778577

申请日：2003-12-01

Applicant: UCB PHARMA SA

Inventor： BROWN DEREK THOMAS ,  BUTLER LISA ,  CROMIE KAREN DOROTHY ,  GRIFFITHS MERYN RUTH ,  LAWSON ALASTAIR D G ,  LIGHTWOOD DANIEL JOHN

IPC: G01N33/52 ,  C07K16/24 ,  G01N33/569 ,  G01N33/58 ,  G01N33/68

Abstract: The present invention provides a homogeneous assay for identifying an antibody producing cell producing an antibody which binds to a selected antigen comprising: a) providing a population of antibody producing cells; b) incubating said population of antibody producing cells with a selected antigen and a labeled anti-antibody antibody, wherein said anti-antibody antibody is capable of distinguishing cells producing an antibody which binds to the selected antigen from those cells which do not; and c) identifying an antibody producing cell capable of producing an antibody which binds to the selected antigen.