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公开(公告)号：CA2584226C
公开(公告)日：2015-09-15
申请号：CA2584226
申请日：2005-11-16
Applicant: UCB PHARMA SA
Inventor： SEHDEV MUKESH , SPITALI MARIANGELA
Abstract: The present invention relates to the manufacture of recombinant antibodies of therapeutic quality. In particular, the invention relates to methods for increasing the yield of functional antibody from large scale fermentations whereby a cultured host cell sample is subjected to a non-lysing treatment.
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公开(公告)号：AU2011284896A1
公开(公告)日：2013-01-24
申请号：AU2011284896
申请日：2011-07-26
Applicant: UCB PHARMA SA
Abstract: The present invention relates to a process for the purification of an antibody fragment from a periplasmic cell extract comprising a first cation exchange chromatography step and a second anion exchange chromatography step.
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公开(公告)号：ES2346673T3
公开(公告)日：2010-10-19
申请号：ES05803527
申请日：2005-11-16
Applicant: UCB PHARMA SA
Inventor： SEHDEV MUKESH , SPITALI MARIANGELA
Abstract: Un método para la preparación de moléculas de anticuerpos recombinantes que comprende cultivar una muestra de célula hospedadora transformada con un vector de expresión que codifica una molécula de anticuerpo recombinante y someter dicha muestra de célula hospedadora a una etapa de tratamiento térmico, caracterizada porque dicha muestra se somete a una etapa de tratamiento no lisante a presión antes de someterse a un aumento de temperatura dentro del intervalo de 30ºC a 70ºC durante un periodo de hasta 24 horas.
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公开(公告)号：CA2582726A1
公开(公告)日：2006-05-26
申请号：CA2582726
申请日：2005-11-16
Applicant: UCB PHARMA SA
Inventor： SPITALI MARIANGELA , SEHDEV MUKESH
Abstract: The present invention relates to the manufacture of recombinant antibodies of therapeutic quality. In particular, the invention relates to methods for increasig the yield of cuntional antibody from large scale fermentations whereby a cultured host cell sample is subjected to a freeze-thaw treatment step.
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公开(公告)号：HK1246330A1
公开(公告)日：2018-09-07
申请号：HK18105961
申请日：2018-05-08
Applicant: UCB PHARMA SA
IPC: C07K20060101
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Patent Agency Ranking
公开(公告)号：SG10201802316VA
公开(公告)日：2018-04-27
申请号：SG10201802316V
申请日：2011-07-26
Applicant: UCB PHARMA SA
Abstract: The present invention relates to a process for the purification of an antibody fragment from a periplasmic cell extract comprising a first cation exchange chromatography step and a second anion exchange chromatography step.
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公开(公告)号：ES2346673T5
公开(公告)日：2018-02-15
申请号：ES05803527
申请日：2005-11-16
Applicant: UCB PHARMA SA
Inventor： SEHDEV MUKESH , SPITALI MARIANGELA
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公开(公告)号：SG186957A1
公开(公告)日：2013-02-28
申请号：SG2013001060
申请日：2011-07-26
Applicant: UCB PHARMA SA
Abstract: The present invention relates to a process for the purification of an antibody fragment from a periplasmic cell extract comprising a first cation exchange chromatography step and a second anion exchange chromatography step.
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公开(公告)号：DE602005021678D1
公开(公告)日：2010-07-15
申请号：DE602005021678
申请日：2005-11-16
Applicant: UCB PHARMA SA
Inventor： SEHDEV MUKESH , SPITALI MARIANGELA
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公开(公告)号：AT469917T
公开(公告)日：2010-06-15
申请号：AT05803527
申请日：2005-11-16
Applicant: UCB PHARMA SA
Inventor： SEHDEV MUKESH UCB CELLTECH , SPITALI MARIANGELA
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