-
公开(公告)号：BRPI0610197A2
公开(公告)日：2010-06-01
申请号：BRPI0610197
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , JAMES ALISTAIR , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin-binding agents, such as antibodies capable of binding to sclerostin, are provided.
-
公开(公告)号：ES2902548T3
公开(公告)日：2022-03-28
申请号：ES19211623
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMAN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Abstract: Un anticuerpo monoclonal que se une a esclerostina humana; aumenta al menos uno de formación de hueso, densidad mineral ósea, contenido mineral óseo, masa ósea, calidad ósea y fuerza ósea en un mamífero; y se une a una parte de la esclerostina humana que consiste en los aminoácidos 51-64, 73-90, 101-117 y 138-149 de la SEQ ID NO: 1, en donde dicha parte tiene las tres de: (a) un enlace disulfuro entre los aminoácidos 57 y 111; (b) un enlace disulfuro entre los aminoácidos 82 y 142; y (c) un enlace disulfuro entre los aminoácidos 86 y 144.
-
公开(公告)号：SI3670528T1
公开(公告)日：2022-01-31
申请号：SI200632414
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
-
公开(公告)号：NO345294B1
公开(公告)日：2020-11-30
申请号：NO20076046
申请日：2007-11-23
Applicant: AMGEN INC , UCB PHARMA SA
Inventor： LATHAM JOHN , PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
IPC: A61K39/395 , A61P19/08 , A61P19/10
-
公开(公告)号：AU2012238247A1
公开(公告)日：2012-11-01
申请号：AU2012238247
申请日：2012-10-08
Applicant: AMGEN INC , UCB PHARMA SA
Inventor： WINTERS AARON GEORGE , LAWSON ALASTAIR , HENRY ALISTAIR JAMES , POPPLEWELL ANDY , PASZTY CHRISTOPHER , SHEN WENYAN , LU HSIENG SEN , LATHAM JOHN , HOFFMANN KELLY SUE , GRAHAM KEVIN , ROBINSON MARTYN KIM , WINKLER DAVID
Abstract: C:\NRPorbl\DCCSZPWA6573 I DOC.4/10/2012 Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided. 4v Lu L % 6 Iii cc ~ O O. . .U te,, Lo~ .CD C; L 0ZDB aweI
-
Patent Agency Ranking
公开(公告)号：NZ563539A
公开(公告)日：2011-04-29
申请号：NZ56353906
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMAN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Abstract: Provided is an antibody or functional fragment thereof that cross-blocks or is cross-blocked from binding of at least one of antibodies Ab-A, Ab-1, Ab-4, Ab-5, Ab-19, Ab-20, and Ab-23 to sclerostin. The antibodies are useful for treating bone-related disorders in mammals.
-
公开(公告)号：ZA200709480B
公开(公告)日：2010-07-28
申请号：ZA200709480
申请日：2007-11-02
Applicant: UCB PHARMA SA , AMGEN INC
Inventor： PASZTY CHRISTOPHER , GRAHAM KEVIN , HOFFMAN KELLY SUE , LAWSON ALASTAIR , POPPLEWELL ANDY , WINKLER DAVID G , ROBINSON MARTYN KIM , HENRY ALISTAIR JAMES , LATHAM JOHN , LU HSIENG SEN , SHEN WENYAN , WINTERS AARON GEORGE
IPC: C07K20060101
Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin-binding agents, such as antibodies capable of binding to sclerostin, are provided.
-
公开(公告)号：CA2607197A1
公开(公告)日：2006-11-09
申请号：CA2607197
申请日：2006-04-28
Applicant: AMGEN INC , UCB PHARMA SA
Inventor： WINTERS AARON GEORGE , LATHAM JOHN , HOFFMANN KELLY SUE , WINKLER DAVID , LAWSON ALASTAIR , LU HSIENG SEN , HENRY ALISTAIR JAMES , SHEN WENYAN , ROBINSON MARTYN KIM , GRAHAM KEVIN , PASZTY CHRISTOPHER , POPPLEWELL ANDY
Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin-binding agents, such as antibodies capable of binding to sclerostin, are provided.
-
公开(公告)号：HUE057097T2
公开(公告)日：2022-04-28
申请号：HUE19211623
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
-
公开(公告)号：LT3670528T
公开(公告)日：2021-12-27
申请号：LT19211623
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
-
-
-
-
-
-
-
-
-
Search Results
95
records
(took 0.039 seconds)
