公开(公告)号：WO1993000039A1

公开(公告)日：1993-01-07

申请号：PCT/EP1992001391

申请日：1992-06-20

Applicant: STEINBECK, Ulrich

IPC: A61B05/06

CPC classification number: A61B5/06 ,  G01V3/102

Abstract: Detection device with single-hand operation for locating a metallic foreign body which has penetrated or been implanted in a human or animal body. A coil system fitted in a sensor rod (10) is connected (19) to a measuring amplifier (14), the output signals of which can be evaluated in a measurement comparator (16) as a measure of the field influence caused by the foreign body.

Abstract translation: 用于定位已经穿透或植入人体或动物体内的金属异物的单手操作的检测装置。 安装在传感器棒（10）中的线圈系统（19）连接到测量放大器（14），其测量放大器（14）可以在测量比较器（16）中评估其输出信号，作为由外部 身体。

公开(公告)号：WO1992012670A1

公开(公告)日：1992-08-06

申请号：PCT/DK1992000014

申请日：1992-01-21

Applicant: RADIOMETER A/S ,  KROGH, Soren-Christian ,  AKSBRO, Erik

Inventor： RADIOMETER A/S

IPC: A61B05/06

CPC classification number: A61B5/1477 ,  A61B5/062 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/1491

Abstract: When performing the method a sensor (1) is used with a coil (15) integrated in a coil circuit. In the coil circuit a magnetic field is generated so that mutual induction can develop between the coil circuit and the surroundings of the sensor (1). The magnetic field in the coil circuit is detected intermittently, and a developed mutual induction is detected as a change of the magnetic field. The position of the sensor is monitored on the basis of said intermittent detection of the magnetic field in the coil circuit. The change of the magnetic field in the coil circuit can be detected in several ways. If the magnetic field is varying, the change may for example be detected as a change of the peak value of the voltage across or the current intensity through the coil circuit or be detected as a phase shift of one of these parameters. The method is used especially to ensure that calibration of the sensor (1) is performed only when the sensor (1) is located in a related calibration chamber (24). The detectable mutual induction is developed between the coil circuit with the coil (15) and an aluminum cup (22) constituting the calibration chamber (24).

Abstract translation: 当执行该方法时，传感器（1）与集成在线圈电路中的线圈（15）一起使用。 在线圈电路中产生磁场，使得线圈电路和传感器（1）周围之间可以产生互感。 线圈电路中的磁场被间歇地检测，并且显影的互感被检测为磁场的变化。 基于线圈电路中的所述磁场的间歇检测来监测传感器的位置。 线圈电路中的磁场变化可以用几种方法来检测。 如果磁场发生变化，则该变化例如可以被检测为通过线圈电路的电压峰值或电流强度的变化，或者被检测为这些参数之一的相移。 该方法特别用于确保仅当传感器（1）位于相关校准室（24）中时才执行传感器（1）的校准。 在与线圈（15）的线圈电路和构成校准室（24）的铝杯（22）之间形成可检测的互感。

公开(公告)号：WO1990013256A1

公开(公告)日：1990-11-15

申请号：PCT/US1990002458

申请日：1990-05-02

Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION

Inventor： WISCONSIN ALUMNI RESEARCH FOUNDATION ,  KORNGUTH, Steven ,  TURSKI, Patrick ,  ROBINS, H., Ian ,  NICKLES, Robert, J.

IPC: A61B05/06

CPC classification number: A61K51/088 ,  A61K47/645 ,  A61K49/085 ,  A61K49/146 ,  A61K2123/00 ,  G01N33/574

Abstract: Improved methods of selectively localizing, imaging and/or treating tumors, which have a net negative charge, employ novel complexes having a net positive charge. The complexes contain a polylysine, a linking agent bound to less than all of the lysyl groups of the polylysine, and an imaging agent or a chemotherapeutic agent which is also bound to the linking agent.

公开(公告)号：WO1990000030A1

公开(公告)日：1990-01-11

申请号：PCT/CH1989000111

申请日：1989-06-08

Applicant: KOCH ELEKTRONIK + APPARATEBAU AG ,  NYBERG, Pekka ,  WEBER, Thomas

Inventor： KOCH ELEKTRONIK + APPARATEBAU AG

IPC: A61B05/06

CPC classification number: G01V3/101 ,  A61B5/06

Abstract: A measurement probe (1) contains a self-adjusting oscillating circuit with a measurement coil (5) and a retroactive coil (6). The measurement coil forms part of an LC oscillating circuit. The oscillator is tuned so that the oscillation periodically ceases and is excited again only after a certain delay time. The measurement parameter is the (low) frequency of the oscillation periods. When the probe (1) approaches the metallic part, the oscillating circuit is damped. The resultant frequency shift of the oscillation periods is measured by an evaluation and indicated optically and/or acoustically or used for control purposes. A metallic object can thus be loacted rapidly and reliably by a probe of small dimensions.

Abstract translation: 测量探头（1）包含具有测量线圈（5）和回溯线圈（6）的自调节振荡电路。 测量线圈构成LC振荡电路的一部分。 振荡器被调谐使得振荡周期性地停止，并且仅在一定延迟时间之后再次被激励。 测量参数是振荡周期的（低）频率。 当探头（1）接近金属部分时，振荡电路被阻尼。 通过评估测量振荡周期的合成频移，并以光学和/或声学方式表示或用于控制目的。 因此，金属物体可以通过小尺寸的探针快速可靠地被吸收。

公开(公告)号：WO1998026715A1

公开(公告)日：1998-06-25

申请号：PCT/TR1996000004

申请日：1996-12-16

Applicant: METIN, Serif, Ildan

IPC: A61B05/06

CPC classification number: A61B5/04025 ,  A61N1/3706

Abstract: This apparatus which shows the place of the temporary pacemaker electrodes or similar conductors put in the veins or arteries and moved to the heart, compares the signals coming from ECG (electrokardiogram) and ICG (intracardiac-electrocardiogram) or second ECG amplifiers in a logic circuit and indicates the results as ventricule or atrium with the twinkles of two different LEDs or in graphics on a screen.

Abstract translation: 显示临时起搏器电极或类似导体放置在静脉或动脉并移动到心脏的位置的装置将来自ECG（心电图）和ICG（心内 - 心电图）的信号或逻辑电路中的第二ECG放大器进行比较 并将结果指示为具有两个不同LED的闪烁或屏幕上的图形的心室或心房。

公开(公告)号：WO1997045057A1

公开(公告)日：1997-12-04

申请号：PCT/ES1997000128

申请日：1997-05-23

Applicant: HERMIDA BORREGO, Gloria ,  REILLO FLOKRANS, Marcos ,  MARTINEZ ESCORIZA, Juan Carlos

IPC: A61B05/06

CPC classification number: A61B5/06 ,  A61B90/98 ,  A61B2090/0805 ,  A61F13/44

Abstract: The system is designed to locate or detect if in a surgical operation compresses or surgical instruments have been forgotten inside the patient. The system comprises the incorporation of a receiver in the compresses, said receiver being formed of a coil and a capacitor for generating an electric current induced when the receiver is subjected to the electromagnetic field created by an external emitter provided with means for setting in operation the receiver and with a coil connected to a capacitor, so that the self-induced current created in the receiver when stopping the electromagnetic field is detected by the emitter itself, thus generating in the emitter a current capable of activating a supply circuit for a light and/or acoustic signalling device which forms part of the emitter itself, to indicate, in the case of activation, the existence of the surgical compress inside the patient who has been operated.

Abstract translation: 该系统设计用于定位或检测是否在外科手术中压缩或手术器械已被忘记在患者体内。 该系统包括在压缩器中并入接收器，所述接收器由线圈和电容器组成，用于当接收器经受外部发射器产生的电磁场时产生电流，该外部发射器设置有用于在操作中设置的装置 接收器和连接到电容器的线圈，使得当停止电磁场时在接收器中产生的自感电流由发射器本身检测，从而在发射器中产生能够激活光供应电路的电流， /或形成发射器本身的一部分的声信号装置，以在激活的情况下指示已经操作的患者内的手术压缩的存在。

公开(公告)号：WO1996032060A1

公开(公告)日：1996-10-17

申请号：PCT/US1996004966

申请日：1996-04-11

Applicant: NAVION BIOMEDICAL CORPORATION

Inventor： NAVION BIOMEDICAL CORPORATION ,  SHAPIRO, Alan, R. ,  KAY, Donald, A.

IPC: A61B05/06

CPC classification number: A61B5/06 ,  A61B5/062 ,  A61B34/20 ,  A61B34/25 ,  A61B2034/107 ,  A61B2034/2051 ,  A61B2090/062 ,  A61B2090/3958 ,  G01V3/105 ,  H01F2005/027

Abstract: A system (10) for externally locating a sensor in tissue, comprising an external probe including at least first and second electromagnetic output coils (12) with non-parallel longitudinal axes; and output coil (2) driver for alternately energizing the first and second output coils, for generating a time-varying magnetic field which penetrates the patient's skin (7); a sensor coil (30), having a longitudinal axis, for developing an induced electrical voltage in response to the time-varying magnetic field; a distance determinator, responsive to the induced voltage from the sensor coil (30), for determining from the induced voltage, the distance between the output coils (12) and the sensor coil (30), independently of the relative angle, in a horizontal plane, between the sensor coil (30) longitudinal axis, and the longitudinal axes of the output coils (12); and a direction determinator for determining and displaying the direction, in the horizontal plane, in which the sensor coil (30) longitudinal axis is pointing.

Abstract translation: 一种用于将传感器外部定位在组织中的系统（10），包括至少包括具有非平行纵向轴线的第一和第二电磁输出线圈（12）的外部探头; 和输出线圈（2）驱动器，用于交替地激励第一和第二输出线圈，用于产生穿透患者皮肤（7）的时变磁场; 传感器线圈（30），具有纵向轴线，用于响应于时变磁场而产生感应电压; 响应于来自传感器线圈（30）的感应电压的距离确定器，用于从感应电压确定输出线圈（12）和传感器线圈（30）之间的距离，独立于水平面的相对角度 在所述传感器线圈（30）纵向轴线与所述输出线圈（12）的纵轴之间的平面; 以及用于确定和显示传感器线圈（30）纵向轴线指向的水平面中的方向的方向确定器。

公开(公告)号：WO1996007352A1

公开(公告)日：1996-03-14

申请号：PCT/US1995010746

申请日：1995-08-24

Applicant: SIMS DELTEC, INC.

Inventor： SIMS DELTEC, INC. ,  GLANTZ, Jerald

IPC: A61B05/06

CPC classification number: A61B5/06

Abstract: The present invention relates to a method and apparatus used to place a catheter (100) having a distal end (106) and a proximal end (102, 104) where the proximal end cannot be trimmed within a patient. The method and apparatus utilize a device operative in locating the tip of a catheter, which includes a detector assembly (200) having a detector (220) and a locator (240). The detector (220) of the detector assembly (200) is locked into position remote from the distal end (106) of the catheter (100) prior to inserting the catheter in the patient. The distal end of the catheter (100) is trimmed, as to define a trimmed distal end, the detector (220) is then unlocked and placed proximate the trimmed end. In the preferred embodiment the detector (220) is locked into place proximate the trimmed distal end and the catheter (100) is placed within the patient.

Abstract translation: 本发明涉及一种用于放置具有远端（106）和近端（102,104）的导管（100）的方法和装置，其中近端不能在患者体内修剪。 该方法和装置利用可操作地定位导管末端的装置，该装置包括具有检测器（220）和定位器（240）的检测器组件（200）。 在将导管插入患者体内之前，检测器组件（200）的检测器（220）被锁定在远离导管（100）的远端（106）的位置。 导管（100）的远端被修剪，以便限定修剪的远端，然后将检测器（220）解锁并放置在修剪端附近。 在优选实施例中，检测器（220）被锁定在修剪的远端附近的适当位置，并且导管（100）被放置在患者体内。

公开(公告)号：WO1993012718A1

公开(公告)日：1993-07-08

申请号：PCT/US1992010852

申请日：1992-12-16

Applicant: PHARMACIA DELTEC, INC.

Inventor： PHARMACIA DELTEC, INC. ,  OWENS, Robert, Craig ,  JOHNSON, Theodore, Arthur

IPC: A61B05/06

CPC classification number: A61B5/06 ,  A61B5/062 ,  A61M25/0127 ,  A61M25/09 ,  A61M2025/09083

Abstract: The invention is directed to a guide wire apparatus and a method for detecting the location of a guide wire within the body of a patient. The apparatus includes a guide wire with an internally-housed sensing member. The guide wire assembly is structured to provide the response, maneuverability and tactile feel comparable to conventional guide wire devices. The apparatus is useful in medical treatments and diagnoses such as angioplasty or catheterization procedures, for detecting obstructions within a blood vessel of a patient, and the like.

Abstract translation: 本发明涉及一种用于检测导线在患者体内的位置的导丝装置和方法。 该装置包括具有内部容纳的感测构件的导丝。 引导线组件被构造成提供与传统的导丝装置相当的响应，机动性和触感。 该装置可用于医疗和诊断，例如血管成形术或导管插入术，用于检测患者血管内的障碍物等。

公开(公告)号：WO1993005707A1

公开(公告)日：1993-04-01

申请号：PCT/US1991007124

申请日：1991-09-27

Applicant: FABIAN, Carl, E.

IPC: A61B05/06

CPC classification number: A61B5/06 ,  A61B90/39 ,  A61B90/90 ,  A61B90/98 ,  A61B2090/0804 ,  A61B2090/3925 ,  A61B2090/3958 ,  A61F13/44 ,  G08B13/2417 ,  G08B13/2434 ,  G08B13/2462 ,  G08B13/2474

Abstract: Apparatus for detecting a surgical implement (20) in human or animal tissue comprises a detector (8) responsive to the presence, within an interrogation zone (10), of a surgical implement (20) to which a marker (18) is secured. The marker (18) is adapted to produce identifying signal characteristics within a frequency band generated in the interrogation zone (10). Variations in the phase and/or direction of the interrogating field and changes in the electromagnetic coupling between markers (18) and receiver (25) optimize coupling therebetween.

Abstract translation: 用于检测人或动物组织中的手术器械（20）的装置包括响应于在询问区（10）内存在固定有标记（18）的手术器械（20）的检测器（8）。 标记（18）适于在询问区（10）中产生的频带内产生识别信号特性。 询问场的相位和/或方向的变化以及标记（18）和接收器（25）之间的电磁耦合的变化优化了它们之间的耦合。