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191.
公开(公告)号:US20240009159A1
公开(公告)日:2024-01-11
申请号:US18037386
申请日:2021-02-01
Inventor: V. Narry KIM , Dongwan KIM , Hyunjoon KIM
IPC: A61K31/196 , A61K31/192 , A61P31/14
CPC classification number: A61K31/196 , A61K31/192 , A61P31/14
Abstract: The present invention relates to an antiviral composition for Betacoronavirus comprising rhein and meclofenamic acid as active components. When the antiviral composition of the present invention is used, an antiviral effect is demonstrated whereby the viral RNA level of SARS-CoV-2 and HCoV-OC43 is suppressed, and thus it is possible to treat or prevent COVID-19 or a cold.
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公开(公告)号:US20230364423A1
公开(公告)日:2023-11-16
申请号:US18027023
申请日:2021-09-30
Inventor: Jin Hyung Lee , Hee-Sup Shin
CPC classification number: A61N1/36082 , A61N1/0534 , A61N5/0622 , A61K31/46 , A61K31/407 , A61P25/00
Abstract: The disclosure pertains to methods for modifying empathy in a subject, such as a human, by modulating type 2 theta oscillations in a brain region of the subject. The methods include increasing empathy in a subject, such as a human, by increasing type 2 theta oscillations in a brain region of the subject, thereby increasing empathy in the subject. The human subject may have a psychiatric or neurological condition that causes suboptimal empathy. Modulating type 2 theta oscillations in a brain region of a subject can be accomplished by optogenetic treatment, electric stimulation of a brain region, administration of a pharmaceutical drug, or a combination thereof. Also provided are systems for performing the methods disclosed herein.
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193.
公开(公告)号:US11785348B2
公开(公告)日:2023-10-10
申请号:US17484189
申请日:2021-09-24
Inventor: Won Shik Choi , Won Jun Choi , Mun Kyu Kang
CPC classification number: H04N23/75 , A61B1/04 , A61B1/07 , G01N21/954 , G02B21/0028 , G02B23/2484 , G02B23/26 , G01N2021/9546 , H04N23/555
Abstract: Disclosed are an endoscopic reflection microscope using an optical fiber bundle and an image acquisition method using the same. The endoscopic reflection microscope includes an incident wave output unit configured to output an incident wave to a target object through any one optical fiber in an optical fiber bundle, a reflected wave receiver configured to receive a reflected wave output from the target object in response to the incident wave through a plurality of corresponding optical fibers in the optical fiber bundle, and an image acquirer configured to establish a reflection matrix corresponding to the reflected wave and to acquire an image in which at least one of phase retardation of the incident wave or phase retardation of the reflected wave is compensated for based on the established reflection matrix.
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194.
公开(公告)号:US11550136B2
公开(公告)日:2023-01-10
申请号:US16757470
申请日:2018-10-16
Inventor: Sang Hee Shim , Ji Woong Kwon
Abstract: According to the present disclosure, an optical signal emitted from a single molecule is received to measure a central location of the single molecule while changing a phase of a structured illumination having a periodic pattern to measure a phase of a pattern in which a fluorescence intensity is periodically changed in accordance with a distance between the pattern and the single molecule while displacing the periodic pattern by a specific interval to measure the central location of the single molecule, thereby improving an accuracy of the central location of the single molecule with low photons and as a result, the resolution of the image may be enhanced.
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195.
公开(公告)号:US20220382041A1
公开(公告)日:2022-12-01
申请号:US17641770
申请日:2020-09-09
Applicant: KOREA BASIC SCIENCE INSTITUTE , INSTITUTE FOR BASIC SCIENCE , GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor: I Jong Kim , Ji Yong Bae , Hong Seung Kim , Geon Hee Kim , Ki Soo Chang , Cheonha Jeon , Il Woo Choi , Chang Hee Nam
Abstract: A spiral phase plate, according to one embodiment, for generating a Laguerre Gaussian beam by reflecting an incident beam emitted from a light source, may comprise: a first quadrant area in which the step height increase rate per unit angle decreases progressively in one direction from the point with the lowest step height to the point with the highest step height; and a second quadrant area in which the step height increase rate per unit angle increases progressively in the one direction.
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196.
公开(公告)号:US20220336821A1
公开(公告)日:2022-10-20
申请号:US17766273
申请日:2020-10-08
Applicant: INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY , SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION , INSTITUTE FOR BASIC SCIENCE
Inventor: Jae Kook KIM , Yung Eun SUNG , Kug Seung LEE , Mi Ju KIM , Sung Jin KIM
Abstract: A method for preparing a transition metal electrochemical catalyst according to an embodiment of the present disclosure includes dissolving a nitrogen precursor and a transition metal precursor in a polyol-based solvent so as to prepare a solution in which transition metal ions and free anions are coordinated, and mixing same with a support so as to prepare a mixture, igniting the mixture so as to carbonize the polyol-based solvent, thereby forming transition metal nanoparticles encompassed by carbon, performing heat treatment in order to carbonize remaining organic matter contained in the mixture, and removing, through acid treatment, impurities and transition metal nanoparticles not encompassed by carbon, and then removing remaining acid through washing and additional heat treatment, thereby a nanocatalyst having a structure in which a single-atom transition metal-nitrogen bonding structure and/or transition metal nanoparticles encompassed by carbon exist is synthesized.
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公开(公告)号:US11428851B2
公开(公告)日:2022-08-30
申请号:US16888970
申请日:2020-06-01
Inventor: Hyun Seok Lee , Young Hee Lee
Abstract: A wavelength multiplexing device is disclosed. When light is irradiated on a first longitudinal end region of a metal nano-structure, surface plasmon polaritons are generated in the first longitudinal end region. The surface plasmon polaritons and the light are coupled with each other to form first coupled surface plasmon polaritons, wherein the first coupled surface plasmon polaritons propagate along and on a surface of the metal nano-structure. When the first coupled surface plasmon polaritons reach a two-dimensional material layer, excitons are induced in the two-dimensional material layer, wherein the induced excitons and the first coupled surface plasmon polaritons are coupled with each other to form second coupled surface plasmon polaritons. The second coupled surface plasmon polaritons propagate along and on a surface of the metal nano-structure toward a second longitudinal end thereof.
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公开(公告)号:US20220267912A1
公开(公告)日:2022-08-25
申请号:US17629234
申请日:2020-07-21
Inventor: Taeghwan HYEON , Yung-Eun SUNG , Heejong SHIN , Byoung-Hoon LEE , Euiyeon JUNG
IPC: C25B1/30 , B01J27/20 , B01J37/02 , B01J23/75 , C25B11/065 , C25B11/075
Abstract: A catalyst for producing hydrogen peroxide and a preparation method therefor are provided. The catalyst for producing hydrogen peroxide according to the embodiments of the present invention comprises a carbon-based support and a catalyst moiety that is bonded to the carbon-based support and comprises an M1-N bonding structure (M1 represents a transition metal atom). The method for preparing a catalyst for producing hydrogen peroxide according to the embodiments of the present invention comprises comprises preparing a carbon-based support, providing a transition metal atom (M1) to the carbon-based support, and doping nitrogen into the carbon-based support.
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公开(公告)号:US20220257963A1
公开(公告)日:2022-08-18
申请号:US17674749
申请日:2022-02-17
Inventor: Jin Woo CHEON , Jae Hyun LEE , Jung Uk LEE
Abstract: The rotating magnetic field generating device for modulating the activity of cells according to an exemplary embodiment of the present invention may include a plurality of magnetic field generating units for generating a rotating magnetic field with an imaginary reference line as a rotation axis that are disposed to be spaced apart from the rotation axis; and an internal space in which a living body can be placed, wherein when an imaginary line in which the magnetic flux direction of the rotating magnetic field is horizontal is referred to as a reference line, the rotating magnetic field on the reference plane may satisfy Relationship Formulas 1 and 2 below, and wherein the area of the rotating magnetic field that satisfies Relationship Formulas 1 and 2 may be 0.1 cm2 or more: |Mc|≥1 mT [Relationship Formula 1] |M75−Mc|/D75≤5.0 T/m [Relationship Formula 2] In Relationship Formulas 1 and 2 above, Mc is the strength of the magnetic field at the position of the rotation axis, D75 is the distance from the rotation axis to the 75% position of the distance to the magnetic force generating unit, and M75 is the strength of the magnetic field at the position D75.
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公开(公告)号:US20220177416A1
公开(公告)日:2022-06-09
申请号:US17536383
申请日:2021-11-29
Inventor: Hyoyoung LEE , Suresh VASIMALLA , Seungeun LEE
IPC: C07C231/10 , C01G23/08 , B01J21/06 , B01J35/00 , B01J37/16 , C07C233/65 , C07D295/192 , C07D401/04
Abstract: Provided is a preparing method of an amide directly from a tertiary amine by using a reduced titanium dioxide (Blue TiO2), which is formed by mixing a titanium dioxide having an anatase phase and a rutile phase with a reducing agent and selectively reducing any one of the anatase phase and the rutile phase, as a photocatalyst.
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