Abstract:
Devices formed of or including biocompatible polyhydroxylkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws (including interference screws), bone plates and bone plating system, surgical mesh, repair patches, slings, cardiovascular patches, orthopedic pins (including bone filling augmentation material), adhesion barriers, stents, guided tissue repair/regeneration devices, articular cartilage repair devices, nerve guides, tendon repair devices, atrial septal defect repair devices, pericardial patches, bulking and filling agents, vein valves, bone marrow scaffolds, meniscus regeneration devices, ligament and tendon grafts, ocular cell implants, spinal fusion cages, skin substitutes, dural substitutes, bone graft substitutes, bone dowels, wound dressings, and hemostats. The polyhydroxyalkanoates can contain additives, be formed of mixtures of monomers or include pendant groups or modifications in their backbones, or can be chemically modified, all to alter the degradation rates. The polyhydroxyalkanoate compositions also provide favorable mechanical properties, biocompatibility, and degradation times within desirable time frames under physiological conditions.
Abstract:
A method of manufacturing a flexible intrinsically antimicrobial absorbent porosic composite controlling for an effective pore size using removable pore-forming substances and physically incorporated, non-leaching antimicrobials. A flexible intrinsically antimicrobial absorbent porosic composite controlled for an effective pore size composited physically incorporated, high-surface area, non-leaching antimicrobials, optionally in which the physically incorporated non-leaching antimicrobial exposes nanopillars on its surface to enhance antimicrobial activity. A kit that enhances the effectiveness of the intrinsically antimicrobial absorbent porosic composite by storing the composite within an antimicrobial container.
Abstract:
Provided is a separator including a separator which consists of a porous polyolefin of 95 wt % or more and an organic additive. A temperature-increase convergence time of the first layer is equal to or longer than 2.9 s·m2/g and equal to or shorter than 5.7 s·m2/g when the first layer is irradiated with a microwave having a frequency of 2455 MHz and an output power of 1800 W after dipping the first layer in N-methylpyrrolidone containing 3 wt % of water, whereas a white index is equal to or more than 86 and equal to or less than 98.
Abstract:
The present invention concerns methods of treating systemic, regional, or local inflammation from a patient suffering or at risk of inflammation comprising administration of a therapeutically effective dose of a sorbent that sorbs an inflammatory mediator in said patient. In some preferred embodiments, the sorbent is a biocompatible organic polymer.
Abstract:
A cellulose sponge cloth containing a net or grid as internal reinforcement is provided, with the sponge cloth further including a uniform distribution of fibers and/or durably softening polymers that are not water-leachable. The sponge cloth is produced by the viscose process by mixing with the fibers and/or the softening polymers and the pore former with cellulose xanthate and forming the resulting sponge cloth raw material into a thin layer. The grid or net is placed onto this layer, followed by a further layer of the sponge cloth raw material. Coagulation and regeneration baths and optional wash baths are used to dissolve the pore former out of the sponge cloth and regenerate the cellulose. The sponge cloth is bend-resistant, it does not break in the dry state. The sponge cloth is envisioned for cleaning and decontamination.
Abstract:
The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
Abstract:
The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
Abstract:
The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
Abstract:
A method for continuously producing sponge bodies (1) made of regenerated cellulose using at least partially agglomerated pore inducers made of sodium sulphate decahydrate is provided. First, a viscose solution is provided. A pore inducer is added to said viscose solution. The viscose solution is laid onto a conveyer belt which is continuously moving. The viscose solution is led through baths on the conveyor belt, resulting in a porous mass made of regenerated cellulose.
Abstract:
The present invention provides a resinous porous article having a high interconnected hole porosity and capable of retaining a large amount of a lubricating oil and does not rust iron and steel, even though an unextracted portion of a pore-forming substance bleeds out when the resinous porous article is used as parts which contact a metal portion or the like and a method of producing the resinous porous article. The resinous porous article is formed by a producing method of molding a resin containing the pore-forming substance into a molding, and extracting the pore-forming substance from the molding with a solvent which does not dissolve the resin therein. The resinous porous article has an interconnected hole porosity not less than 30%. The pore-forming substance consists of an alkali compound.