Abstract:
PURPOSE: A composition containing herb extract for skin care or plasty is provided to promoter differentiation of mesenchymal stem cells to adipocytes. CONSTITUTION: A composition for promoting differentiation to adipocytes contains Cinnamomum cassia extract as an active ingredient. The composition increases fat tissue. The mesenchymal stem cells are human bone marrow stem cells.
Abstract:
PURPOSE: A cosmetic composition containing bee venom or bee venom extract is provided to improve anti-oxidation, anti-aging, and anti-wrinkle. CONSTITUTION: A cosmetic composition contains bee venom or bee venom extract as an active ingredient. The content of the bee venom or bee venom extract is 0.0001-30 weight%. The venom extract is isolated using water, organic solvent or mixture solvent thereof. The organic solvent is ethanol, methanol, butanol, ether, ethyl acetate, or chloroform. The mixture solvent is 10-90%(v/v) ethanol.
Abstract:
PURPOSE: A screening method of a skin improvement material is provided to effectively screen the skin improvement material capable of preventing skin ageing, maintaining skin moisture, and improving skin barrier function. CONSTITUTION: A screening method of a skin improvement material comprises the following steps: processing a candidate material to a skin cell; detecting an expression amount change of MAP17(membrane-associated protein 17kd); and selecting the candidate material which induces the change of the expression amount as the skin improvement material. The skin cell is a skin keratinocyte.
Abstract:
PURPOSE: A method for effectively manufacturing blue pigments from gardenia jasminoids is provided to prepare blue pigments from gardenia jasminoids in a short time and to generate genipin by removing sugar from geniposide. CONSTITUTION: A method for effectively manufacturing blue pigments from gardenia jasminoids comprises the steps of: (i) preparing gardenia jasminoids extract by extracting gardenia jasminoids fruits with methanol or ethanol; (ii) obtaining genipin from which sugar is removed by reacting the gardenia jasminoids extract with enzymes in an ionic liquid; and (iii) reacting the genipin with amino acid, primary amine or peptide. The ionic liquid is [BMIM][BF4] or [BMIM][PF6].
Abstract:
PURPOSE: A composition for suppressing differentiation and growth of adipocytes is provided to treat or prevent circulatory system disease or ischemic heart disease. CONSTITUTION: A composition for suppressing differentiation or growth of adipocytes contains 0.00001 to 15 weight% of chemerin. The adipocyte is human bone marrow mesenchymal stem cell. A pharmaceutical composition is used in the form of oral administration formulation or injection. The oral administration formulation is formulated in capsule, tablet, suspension, syrup or powder. A functional health food composition for preventing or treating diabetes, hyperlipidemia, hypercholesterolemia, circulatory system diseases contains 0.00001-10 weight% of chemerin. The health food is used in the form of caramel, chocolate, diet bar or snack. A cosmetic composition for treating obesity contains 0.00001-10 weight% of chemerin as an active ingredient. The cosmetic composition is used in the form of massage cream, body lotion, body cream, body oil, or body essence.
Abstract:
PURPOSE: A skin external composition containing medicinal herb extract is provided to promote regeneration of wound tissue and suppress skin injury and aging. CONSTITUTION: A skin external composition for anti-inflammation contains medicinal herbs including Taraxacum platycarpum H. Dahlsi, Cimicifuga heracleifolia, Dioscorea opposite, or Angelica tenuissima Nakai extract as an active ingredient. The skin external composition for wound healing and anti-aging contains the medicinal herbs. The medicinal herb extract is obtained using water or organic solvent. The organic solvent is ethanol, methanol, butanol, ether, ethylacetate, or chloroform.
Abstract:
PURPOSE: A composition containing pharbitidis seed, Anthriscs aemula Schisch and their mixture for body sliming is provided to suppress adipocyte differentiation and reduce lipid level. CONSTITUTION: A composition for body sliming contains pharbitidis seed extract, Anthriscs aemula Schisch extract or their mixture as an active ingredient. A composition for suppressing adipocyte differentiation contains the pharbitidis seed extract, Anthriscs aemula Schisch extract or their mixture as an active ingredient. Mesenchymal stem cells from human bone marrow are differentiated to adipocytes. The composition for sliming is used in the form of cosmetic composition, health food or pharmaceutical composition.
Abstract:
PURPOSE: A skin external composition for anti-aging containing pine extract is provided to smooth wrinkle and use in skin care and cosmetic product. CONSTITUTION: A skin external composition contains 0.0001 - 10 weight% of pine extract as an active ingredient. The composition is a composition for preventing aging and wrinkle. A method for producing the skin external composition containing the pine extract comprises: a step of pulverizing the pine; a step of extracting through cooling or heating with low irritative solvent; and a step of concentrating the extract in a distillation device with a cooling condenser. The low irritative solvent is hydrous or anhydrous low alcohol of 1-4 carbon atoms, acetone, ethylacetate, diethylacetate, benzene, chloroform, or hexane.
Abstract:
PURPOSE: A cosmetic composition containing Sctellaria baicalensis georgi extract is provided to suppress expression of elastase and collagenase and prevent aging. CONSTITUTION: A cosmetic composition for anti-aging contains Sctellaria baicalensis georgi extract. A method for producing Sctellaria baicalensis georgi extract comprises: a step of boiling, steaming, roasting, and frying the Sctellaria baicalensis georgi in fire through processing herbal medicine; and a step of extracting Sctellaria baicalensis georgi extract using water or organic solvent to obtain extract. The organic solvent is ethanol, methanol, butanol, ether, ethyl acetate or chloroform.