Abstract:
Improved devices, systems (14), and methods for sensing and/or identifying signals from within a signal detection region are well-suited for identification of spectral codes. Large numbers of independently identifiable spectral codes can be generated by quite small bodies (12a, 12b), and a plurality of such bodies or probes (12a, 12b) may be present within a detection region. Simultaneously imaging of identifiable spectra (60) from throughout the detection region allows the probes (12a, 12b) to be identified. As the identifiable spectra can be treated as being generated from a point source within a much larger detection field, a prism, diffractive grading, holographic transmissive grading, or the like (56) can spectrally disperse the images of the labels across a sensor surface. A CCD (18) can identify the relative wavelengths of signals making up the spectra. Absolute signal wavelengths may be determined by determining positions of the labels, by an internal wavelength reference within the spectra (60), or the like.
Abstract:
A microassay card (10) includes an upper layer (12) containing wells (14) for receiving a liquid sample (16). A second layer (20) of the card (10), beneath the first layer (12), includes a supporting surface (223) bound to a reactive species (114). A third layer (26) includes a superabsorbent support (26) impregnated with an indicator (228). Typically, the indicator (228) is a substrate (228) for an enzyme (16), such as a reduced dye precursor and a source of hydrogen peroxide necessary for the action of the enzyme (116), upon the substrate to cause a spectral change in the absorbent layer (26). By selecting the structure of the first (12) and second (20) layers, the card (10) can be formatted for a displacement assay or a competitive assay. The microassay card (10) of the present invention is particularly useful for drug testing.
Abstract:
An apparatus (10) for inspecting the surface of an object S moving in the direction of travel (23) relative to the apparatus comprises a modular sensing head assembly (11) including a plurality of sensing head modules (12, 13), each of which includes a number of sensing stations (16 - 21). Each sensing station includes a light source (77, 81, 84) for generating a line of light extending across substantially the width of the surface of the object and a plurality of optical detector means for detecting light scattered from the line of light by the surface of the object. The optical detectors are positioned and oriented to receive scattered light scattered along paths lying in detection planes which are perpendicular to each other and perpendicular to the surface of the object. Signal processing electronics are provided to convert the light received by the detectors into analog signals which are multiplexed, converted to digital signals, filtered and then compared to preselected thresholds to determine the existence of any defects in the surface.
Abstract:
Appareil (10) servant à examiner la surface d'un objets se déplaçant dans un sens de parcours (23) par rapport à l'appareil. Ledit appareil (10) est constitué d'un ensemble tête de détection (11) modulaire comprenant une pluralité de modules (12, 13) de tête de détection qui comportent chacun plusieurs unités de détection (16, 21). Chaque unité de détection comprend une source de lumière (77, 81, 84) qui génère un rayon de lumière s'étendant pratiquement sur la largeur de la surface de l'objet, et plusieurs détecteurs optiques qui détectent la lumière du rayon de lumière qui est dispersée par la surface de l'objet. Les détecteurs optiques sont positionnés et orientés de manière à recevoir la lumière dispersée selon des trajectoires situées dans des plans de détection qui sont perpendiculaires entre eux et par rapport à la surface de l'objet. Des systèmes électroniques de traitement des signaux sont prévus pour transformer la lumière reçue par les détecteurs en signaux analogiques qui sont multiplexés, convertis en signaux numériques, filtrés et ensuite comparés à des seuils présélectionnés pour déterminer la présence d'un quelconque défaut dans cette surface.
Abstract:
Le dispositif selon l'invention comporte une pluralité de cartouches (1) contenant du sérum et des réactifs en sachet ; ces cartouches sont insérées dans un dispositif de traitement automatique (40) permettant la mise en contact du sérum avec les différents réactifs et la lecture des réactions obtenues.
Abstract:
An apparatus responsive to optical changes in a waveguide when the latter is contacted with an analyte capable of reacting with a specific reactant thereto attached to the surface of said guide involves, for containing the analyte, an interchangeable round bottomed cuvette temporarily held by a suitably shaped carrier in working relationship with the optical components of the apparatus, this arrangement ensuring a correct optical orientation thereof relative to said component whenever the exact positioning of the cuvette.
Abstract:
A method for the measurement of luminescence radiation in which the radiation is measured vertically above of a vessel so that the vessel and the optical system leading to the detector is protected from external radiation.