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    Interchangeable tip-open cell fluorometer
    201.
    发明申请
    Interchangeable tip-open cell fluorometer 有权
    可互换尖端开细胞荧光计

    公开(公告)号：US20050168741A1

    公开(公告)日：2005-08-04

    申请号：US10769631

    申请日：2004-01-30

    Applicant: Rodney Banks

    Inventor： Rodney Banks

    IPC: G01N21/64

    CPC classification number: G01N21/645 ,  G01N33/18 ,  G01N2021/157 ,  G01N2021/6482 ,  G01N2201/0221 ,  G01N2201/024 ,  G01N2201/062 ,  G01N2201/064

    Abstract: Described and claimed is an interchangeable tip-open cell fluorometer comprising a housing and a fluorometric probe tip interchangeably connected to the housing, the probe tip including a probe tip housing defining an open cell and enclosing a probe optical arrangement, the probe optical arrangement including an excitation source and a fluorescence detector wherein the excitation source is aimed directly into the fluorescence detector such that a sample can be fluorometrically detected. Also claimed is a method of using this interchangeable tip-open cell fluorometer for detecting fluorescent signals emitted by one or more fluorophores from samples from a natural or industrial water system. The fluorometer, when coupled with a controller, is capable of monitoring and optionally controlling an industrial process or system.

    Abstract translation: 描述和要求保护的是可互换的尖端开孔单元荧光计，其包括壳体和可互换地连接到壳体的荧光探针尖端，探针尖端包括限定开放单元并包围探针光学布置的探针尖端壳体，探针光学布置包括 激发源和荧光检测器，其中激发源直接瞄准荧光检测器，使得样品可被荧光测量。 还要求保护的是使用这种可互换的尖端开放式荧光计来从天然或工业水系统的样品中检测由一种或多种荧光团发射的荧光信号的方法。 当与控制器耦合时，荧光计能够监测和可选地控制工业过程或系统。

    Multiplexed, absorbance-based capillary electrophoresis system and method
    202.
    发明申请
    Multiplexed, absorbance-based capillary electrophoresis system and method 有权
    多重吸光度毛细管电泳系统及方法

    公开(公告)号：US20040070758A1

    公开(公告)日：2004-04-15

    申请号：US10269646

    申请日：2002-10-11

    Inventor： Jeremy R. Kenseth ,  Ho-Ming Pang ,  Roy F. Strasburg

    IPC: G01N021/00

    CPC classification number: G01N27/44721 ,  G01N27/44782 ,  G01N2021/0346 ,  G01N2201/064

    Abstract: A multiplexed, absorbance-based electrophoresis system for analyzing multiple samples simultaneously without use of a mask or slit comprising a light source, a planar array of capillary tubes and a detector positioned off-axis with the light source and positioned on-axis with and parallel to the planar array of capillary tubes. Other embodiments include vacuum use attached to the capillary tubes to increase the speed of detection.

    Abstract translation: 一种复用的基于吸光度的电泳系统，用于同时分析多个样品而不使用掩模或狭缝，其包括光源，毛细管的平面阵列和与光源离轴定位的检测器并且与轴平行 到毛细管的平面阵列。 其他实施例包括附着到毛细管的真空使用以增加检测速度。

    Flow cells utilizing photometric techniques
    203.
    发明申请
    Flow cells utilizing photometric techniques 有权
    采用光度测量技术的流动池

    公开(公告)号：US20030174322A1

    公开(公告)日：2003-09-18

    申请号：US10068683

    申请日：2002-02-06

    Inventor： Yuri Gerner ,  Carl W. Sims ,  Thomas J. Thielen

    IPC: G01N021/05

    CPC classification number: G01N21/05 ,  G01N21/0317 ,  G01N2021/0346 ,  G01N2201/064

    Abstract: A flow cell for transporting fluid in a radiant energy field includes a cell structure having a tube extending therethrough including a radiant energy blocking portion integral therewith. In a particular embodiment, the cell structure includes one or more end caps having a protrusion extending therefrom, wherein the protrusion may be inserted into the tube to create a fluid seal, the end caps including open channels for transporting fluid and radiant energy therethrough, and the tube in the cell structure includes an efficient radiant energy transmission lining that is spaced from the end cap protrusions, thereby forming a gap volume in the flow cell open channel, which gap volume may be calibrated such that radiant energy losses may be standardized in respective flow cells transporting fluids having various indexes of refraction.

    Abstract translation: 用于在辐射能场中传输流体的流动池包括具有延伸穿过其中的管的电池结构，其包括与其成一体的辐射能阻挡部。 在特定实施例中，电池结构包括一个或多个具有从其延伸的突起的端盖，其中突出部可以插入管中以产生流体密封，端盖包括用于输送流体和辐射能的开口通道，以及 电池结构中的管包括与端盖突起间隔开的有效的辐射能传输衬里，从而在流动池开放通道中形成间隙体积，该间隙体积可以被校准，使得辐射能量损失可以在相应的 输送具有各种折射率的流体的流动池。

    On-line titration using colorimetric end point detection
    204.
    发明授权
    On-line titration using colorimetric end point detection 失效
    使用比色终点检测进行在线滴定

    公开(公告)号：US5181082A

    公开(公告)日：1993-01-19

    申请号：US514061

    申请日：1990-04-24

    Applicant: Anthony C. Jeannotte ,  Anthony C. Gilby ,  M. Charles Cheney ,  Barry J. Meneghelli

    Inventor： Anthony C. Jeannotte ,  Anthony C. Gilby ,  M. Charles Cheney ,  Barry J. Meneghelli

    IPC: G01N21/27 ,  G01N21/05 ,  G01N21/77 ,  G01N21/83 ,  G01N21/85 ,  G01N31/16

    CPC classification number: G01N21/83 ,  G01N21/8507 ,  G01N2021/054 ,  G01N2021/1744 ,  G01N2201/064 ,  G01N2201/0642 ,  G01N2201/08 ,  G01N2201/084

    Abstract: Radiant energy is transmitted to a probe element including an interior conical reflecting surface and a fluid sample chamber. Portions of the light which have been transmitted, partially attenuated, or scattered by a fluid sample in the sample chamber are directed by at least a portion of the interior conical reflecting surface to means for collecting the transmitted, partially attenuated, or scattered light. A stilling valve incorporated into the probe element enables elimination of entrained gas bubbles from the chamber. A specific application of the probe is disclosed in which a titration analyzer is combined with electro-optic signal conversion and processing circuits and a probe according to the invention to provide titration colorimetric endpoint determination in measuring the free fatty acid content of a fluid such as a edible oil or fat.

    Abstract translation: 辐射能量传递到包括内部锥形反射表面和流体样品室的探针元件。 通过样品室中的流体样品透射，部分衰减或散射的光的部分由内部锥形反射表面的至少一部分引导到用于收集透射的，部分衰减的或散射的光的装置。 结合到探针元件中的静止阀能够消除来自腔室的夹带的气泡。 公开了探针的具体应用，其中滴定分析仪与电光信号转换和处理电路组合，根据本发明的探针结合以提供滴定比色终点测定，以测量流体的游离脂肪酸含量，例如 食用油或脂肪。

    Turbidimeter employing a semiconductor laser diode and a photodiode
    205.
    发明授权
    Turbidimeter employing a semiconductor laser diode and a photodiode 失效
    浊度计采用半导体激光二极管和光电二极管

    公开(公告)号：US4725148A

    公开(公告)日：1988-02-16

    申请号：US739319

    申请日：1985-05-30

    Applicant: Isao Endo ,  Teruyuki Nagamune ,  Ichiro Inoue ,  Kozo Inoue ,  Tadashi Nohira ,  Ikuzo Kagami ,  Tatsuya Iwakura

    Inventor： Isao Endo ,  Teruyuki Nagamune ,  Ichiro Inoue ,  Kozo Inoue ,  Tadashi Nohira ,  Ikuzo Kagami ,  Tatsuya Iwakura

    IPC: G01N21/59 ,  G01N21/53 ,  G01N21/85 ,  G01N21/84

    CPC classification number: G01N21/8507 ,  G01N21/534 ,  G01N2201/0621 ,  G01N2201/0631 ,  G01N2201/064

    Abstract: In a turbidimeter for measuring a turbidity of a test solution to be measured i.e. culture solution in a fermentation apparatus, a semiconductor laser diode and a semiconductor photodiode are integrally arranged in a detection portion of the turbidimeter in such a manner that a laser beam emitted from the semiconductor laser diode is made incident upon the semiconductor photodiode through the test solution. Moreover, a protection circuit for the semiconductor laser diode and the semiconductor photodiode is also arranged in the turbidimeter to cut off a current flowed therethrough when an environmental temperature becomes above a predetermined temperature. Therefore, the turbidimeter can be made small in size and light in weight, and the turbidity can be measured accurately over wide range.

    Abstract translation: 在浊度计中，用于测量待测试的测试溶液的浊度，即发酵设备中的培养溶液，半导体激光二极管和半导体光电二极管一体地布置在浊度计的检测部分中，使得从 半导体激光二极管通过测试溶液入射到半导体光电二极管上。 此外，当环境温度高于预定温度时，用于半导体激光二极管和半导体光电二极管的保护电路也布置在浊度计中以截断流过其中的电流。 因此，可以使浊度计尺寸小，重量轻，并且可以在宽范围内精确地测量浊度。

    Selective collector for the wide-angle portion of a radiation beam
    206.
    发明授权
    Selective collector for the wide-angle portion of a radiation beam 失效
    用于辐射束的宽角度部分的选择性收集器

    公开(公告)号：US3622796A

    公开(公告)日：1971-11-23

    申请号：US3622796D

    申请日：1969-11-13

    Applicant: TE CO THE

    Inventor： HARRIS CLYDE W

    IPC: G01J3/02 ,  G01N21/64 ,  G01N21/22

    CPC classification number: G01J3/02 ,  G01J3/0216 ,  G01N21/645 ,  G01N2021/6463 ,  G01N2201/064

    Abstract: Radiation-translating devices such as resonance backscatter cells and other fluorescent bodies receive incident radiation in a concentrated beam and emit processed radiation in diffuse form. The present system separates such processed radiation from any unprocessed incident radiation specularly reflected from the cell window by receiving both in an optical light pipe coaxial with the unwanted radiation. The light pipe is laterally immersed in an optical medium of such index that the unwanted radiation is retained by total reflection in the pipe and a major portion of the initially diffuse processed radiation is transmitted through the sidewalls to form an annular beam of moderate solid angle suitable for further processing by conventional optics. The same light pipe may also supply the beam of incident radiation to the translating device.

    蛍光検出装置及び蛍光検出方法
    210.
    发明专利
    蛍光検出装置及び蛍光検出方法 有权
    荧光检测器和荧光检测方法

    公开(公告)号：JP2015064281A

    公开(公告)日：2015-04-09

    申请号：JP2013198192

    申请日：2013-09-25

    Applicant: 株式会社日立ハイテクノロジーズ

    Inventor： 内保 裕一 ,  穴沢 隆 ,  芳賀 孝信

    IPC: G01N21/64

    CPC classification number: G01N21/645 ,  G01N27/44721 ,  G01N21/6452 ,  G01N2201/064 ,  G01N27/44726

    Abstract: 【課題】本発明は、チップ材料からの自家蛍光を低減し、かつ安価で小型な蛍光検出装置を提供することを目的とする。 【解決手段】蛍光検出装置は、基板に保持された少なくとも1つの測定対象からの光を集光するレンズと、前記光を測定する受光器と、前記受光器と前記レンズの間で前記受光素子に対面し、前記レンズの焦点位置に配置された遮光板と、を備える。前記遮光板は、少なくとも1つのピンホールを有し、前記受光器は、前記レンズの焦点から外れた位置に配置された単板の受光素子を備える。前記単板の受光素子には、複数の色の画素を1単位とする画素群が複数個配列されている。前記受光器は、前記ピンホールを通った前記光を前記受光素子によって受光する。 【選択図】図1A

    Abstract translation: 要解决的问题：提供能够降低芯片材料的自发荧光并确保低成本和小尺寸的荧光检测器。解决方案：荧光检测器包括：聚焦来自保持在基板上的至少一个测量对象的光的透镜; 测量光的光接收单元; 以及面对光接收单元和透镜之间的光接收元件并且布置在透镜的焦点位置的屏幕。 屏幕包括至少一个针孔，并且光接收单元包括布置在偏离透镜的焦点的位置处的单个光接收元件。 多个像素组以单个光接收元件的阵列排列，其中多个像素的颜色被设置为一个单位。 光接收单元通过光接收元件接收通过针孔的光。

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