公开(公告)号：CA2158167A1

公开(公告)日：1994-10-13

申请号：CA2158167

申请日：1994-03-19

Applicant: BASF AG

Inventor： TREIBER HANS-JOERG ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: A61K31/495 ,  A61P25/00 ,  A61P25/08 ,  A61P25/20 ,  A61P25/24 ,  A61P25/26 ,  C07D235/00 ,  C07D241/00 ,  C07D487/04

Abstract: Described are imidazoloquinoxalinones of the formula (I) in which A and R1 to R6 are as defined in the description, plus their preparation. The compounds described can be used in the preparation of drugs for use in the treatment of neurodegenerative ailments and neurotoxic disorders of the central nervous system as well as in the preparation of spasmolytics, anti-epileptics, anxiolytics and antidepressants.

公开(公告)号：MX9307736A

公开(公告)日：1994-06-30

申请号：MX9307736

申请日：1993-12-08

Applicant: BASF AG

Inventor： HOFMANN HANS PETER ,  SCHLECKER RAINER ,  TREIBER HANS-JOERG ,  BEHL BERTHOLD

IPC: A61K31/505 ,  A61P25/02 ,  A61P25/20 ,  C07D487/04 ,  A61K31/33

Abstract: PCT No. PCT/EP93/03331 Sec. 371 Date Jun. 1, 1995 Sec. 102(e) Date Jun. 1, 1995 PCT Filed Nov. 27, 1993 PCT Pub. No. WO94/13672 PCT Pub. Date Jun. 23, 1994Novel triazoloquinazolines of the formula I gs stated in the description, and their preparation are described. The compounds are suitable for controlling diseases.

公开(公告)号：MX9303153A

公开(公告)日：1994-04-29

申请号：MX9303153

申请日：1993-05-27

Applicant: BASF AG

Inventor： LUBISCH WILFRED ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: A61K31/495 ,  A61K31/498 ,  A61P25/00 ,  A61P25/08 ,  A61P25/20 ,  A61P25/22 ,  A61P25/24 ,  A61P25/26 ,  C07D241/44 ,  C07D241/52 ,  C07D401/04 ,  C07D403/04 ,  C07D487/12 ,  C07D487/14

Abstract: Quinoxaline-2,3-(1H,4H)diones of the general formula I in which the variables have the following meaning: R is hydrogen; an aliphatic radical having up to 12 C atoms, which can carry one of the following substituents: phenyl, cyclopentyl, cyclohexyl or a group -CO-R , -CO-O-R or -CO-NH-R , where R denotes hydrogen, C1-C4-alkyl, phenyl, benzyl or 1-phenylethyl; a cycloaliphatic radical having up to 12 C atoms, or a phenyl group, where the cyclic groups contained in R can carry up to three of the following substituents: C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy, C1-C4-haloalkoxy, halogen, nitro, cyano, -CO-O-R and -CO-NH-R ; R is a pyrrol-1-yl group which can carry up to two of the following substituents: C1-C4-alkyl, phenyl, phenylsulphonyl, nitro, cyano and one of the groups -CO-O-R , -CO-NH-R , -CH2-O-R , -O-R and -CH=NO-R ; R is identical or different radicals from the following: C1-C4-alkyl, C1-C4-alkoxy, trifluoromethyl, trichloromethyl, trifluoromethoxy, trichloromethoxy, fluorine, chlorine, bromine, iodine, nitro, cyano and one of the groups -CO-O-R and -CO-NH-R and a fused benzene ring; n is 0 to 3. Quinoxaline-2,3-(1H,4H)diones I' in which R has the meaning mentioned. The compounds I and I' are suitable as medicines for human and veterinary medicine.

公开(公告)号：HU9303478D0

公开(公告)日：1994-04-28

申请号：HU9303478

申请日：1993-12-07

Applicant: BASF AG

Inventor： STEINER GERD ,  UNGER LILIANE ,  BEHL BERTHOLD ,  TESCHENDORF HANS-JUERGEN

IPC: A61K31/38 ,  A61K31/395 ,  A61K31/40 ,  C07D209/52 ,  C07D401/04 ,  C07D403/04 ,  C07D409/04

公开(公告)号：CA2107665A1

公开(公告)日：1992-10-17

申请号：CA2107665

申请日：1992-04-04

Applicant: BASF AG

Inventor： STEINER GERD ,  UNGER LILIANE ,  HOFMANN HANS P ,  TESCHENDORF HANS-JUERGEN ,  BEHL BERTHOLD ,  BINDER RUDOLF

IPC: A61K31/445 ,  A61K31/4433 ,  A61K31/451 ,  A61P25/20 ,  A61P25/24 ,  A61P25/26 ,  C07D211/22 ,  C07D211/46 ,  C07D211/48 ,  C07D211/52 ,  C07D211/70 ,  C07D409/04 ,  C07D211/18 ,  A61K31/44 ,  C07D211/44 ,  C07D409/06

Abstract: 2107665 9218480 PCTABS00016 The description relates to compounds of formula (I) in which A-B-D, R1, R2, R3 and n have the meanings given in the specification, and their production. The compounds are suitable for the treatment of diseases.