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    Photoacoustic imaging device, probe unit used in the same, and operation method of photoacoustic imaging device
    222.
    发明专利
    Photoacoustic imaging device, probe unit used in the same, and operation method of photoacoustic imaging device 有权
    照相成像装置，其中使用的探针单元和照相成像装置的操作方法

    公开(公告)号：JP2012168091A

    公开(公告)日：2012-09-06

    申请号：JP2011030741

    申请日：2011-02-16

    Applicant: Fujifilm Corp ,  富士フイルム株式会社

    Inventor： IRISAWA SATORU

    IPC: G01N21/00 ,  A61B8/00

    CPC classification number: G01N21/1702 ,  A61B5/0095 ,  G01N2201/0846

    Abstract: PROBLEM TO BE SOLVED: To facilitate position matching of a plurality of branched light and a plurality of optical fibers in photoacoustic imaging implemented by using the plurality of optical fibers and guiding laser beams.SOLUTION: A photoacoustic imaging device includes a light branching section 12 having a branching diffraction optical element 40 for branching a laser beam Lo incident from an upstream side of the optical system into a plurality of branched beams Ld according to a prescribed branching pattern; and a bundle fiber 14 including a plurality of optical fibers each having a core 13a/clad 13b structure, and in which one end surfaces 13e of a plurality of optical fibers 13 at one end surface 14e of the bundle fiber 14 are arrayed while matching the branching pattern. The bundle fiber 14 is arranged so that the plurality of branched beams Ld are respectively incident to cores 13a of the plurality of optical fibers 13.

    Abstract translation: 要解决的问题：为了促进通过使用多根光纤并引导激光束实现的光声成像中的多个分支光和多个光纤的位置匹配。 光声成像装置包括：光分支部12，其具有分支衍射光学元件40，用于将根据规定的分支图案从光学系统的上游侧入射的激光束Lo分支成多个分支光束Ld ; 以及包括多个光纤的束光纤14，每个光纤具有芯13a /包层13b结构，并且其中在束纤维14的一个端表面14e处的多个光纤13的一个端面13e被排列，同时匹配 分支模式。 束纤维14被布置成使得多个分支束Ld分别入射到多根光纤13的芯13a。版权所有（C）2012，JPO＆INPIT

    Biological measurement apparatus
    225.
    发明专利
    Biological measurement apparatus 有权
    生物测量仪器

    公开(公告)号：JP2009103619A

    公开(公告)日：2009-05-14

    申请号：JP2007276770

    申请日：2007-10-24

    Applicant: Hamamatsu Photonics Kk ,  浜松ホトニクス株式会社

    Inventor： UEDA YUKIO ,  YAMASHITA YUTAKA

    IPC: G01N21/17 ,  A61B10/00

    CPC classification number: G01N21/4795 ,  A61B5/0091 ,  A61B5/4312 ,  G01N2201/0846

    Abstract: PROBLEM TO BE SOLVED: To provide a biological measurement apparatus for measuring a location at which a light adsorber such as a tumor exists in the entire to-be-measured region. SOLUTION: The biological measurement apparatus 10 includes: a vessel 12 for holding an optical interface material 20; a light irradiation means for irradiating the to-be-measured region immersed in the optical interface material 20 with first and second lights having different wavelengths; a light detection means for detecting a diffusion light from the to-be-measured region; and a calculation/control section 14 for calculating internal information from an output signal of the light detection means. The wavelength λ1 of the first light is a wavelength at which an absorption coefficient of the to-be-measured region is substantially equal to an absorption coefficient of a medium. The wavelength λ2 of the second light is a wavelength at which the absorption coefficient of the to-be-measured region is larger than the absorption coefficient of the medium. The calculation/control section 14 calculates the internal information from the output signal related to the diffusion light of the first light, and calculates a boundary between the to-be-measured region and the optical interface material 20 from the output signal related to the diffusion light of the second light. COPYRIGHT: (C)2009,JPO&INPIT

    Abstract translation: 要解决的问题：提供一种用于测量在整个被测量区域中存在肿瘤等光吸收剂的位置的生物测定装置。 生物测定装置10包括：保持光学界面材料20的容器12; 光照射装置，用于用浸没在光学界面材料20中的待测量区域照射具有不同波长的第一和第二光; 光检测装置，用于检测来自待测区域的漫射光; 以及用于根据光检测装置的输出信号计算内部信息的计算/控制部分14。 第一光的波长λ1是待测量区域的吸收系数基本上等于介质的吸收系数的波长。 第二光的波长λ2是待测量区域的吸收系数大于介质的吸收系数的波长。 计算/控制部分14根据与第一光的扩散光相关的输出信号计算内部信息，并根据与扩散相关的输出信号计算被测量区域和光学界面材料20之间的边界 第二个光的光。 版权所有（C）2009，JPO＆INPIT

    System and method for molecule sensing using evanescent light coupling approach
    229.
    发明授权
    System and method for molecule sensing using evanescent light coupling approach 有权

    公开(公告)号：US09921164B2

    公开(公告)日：2018-03-20

    申请号：US15418350

    申请日：2017-01-27

    Applicant: UVic Industry Partnerships Inc.

    Inventor： Tao Lu

    IPC: G01N21/65 ,  G02B6/032 ,  G02B6/255

    CPC classification number: G01N21/658 ,  G01N21/65 ,  G01N2201/0612 ,  G01N2201/08 ,  G01N2201/0846 ,  G02B6/032 ,  G02B6/2551 ,  G02B6/2821 ,  G02B6/2856

    Abstract: A system and a method for optical sensing of single molecule or molecules in various concentrations are provided. The optical sensor system comprises a first fiber, a second fiber, a light source and a detection device. The first fiber and the second fiber are fused together to form an optical coupler. The first fiber serves as the passageway for the analyte, while the second fiber serves as the waveguide for the light that will interact with the said analyte. One end of the second fiber is connected to the light source (e.g. laser), and the opposite end is connected to the detection device (e.g. spectrometer). The analyte is introduced into the first fiber through one of its ends, and is allowed to flow through inside the hollow core of the said first fiber. When light is delivered through the input end of the second fiber, the evanescent light is formed in the optical coupler and is allowed to interact with the analyte in the first fiber. One scenario in this analyte-light interaction results in, for example, the generation of Raman emission that is used as the probing signal. The spectrum of the Raman emission is analyzed by the detection device to determine the presence of target molecule.

    FOOD INTEGRITY PROBE HEAD
    230.
    发明申请
    FOOD INTEGRITY PROBE HEAD 审中-公开

    公开(公告)号：US20170328770A1

    公开(公告)日：2017-11-16

    申请号：US15592274

    申请日：2017-05-11

    Applicant: OCEAN OPTICS, INC.

    Inventor： THOMAS HOPKINS ,  DIETER BINGEMANN ,  DAVID CREASEY

    IPC: G01J3/02 ,  G01N33/02

    CPC classification number: G01J3/0218 ,  G01N21/49 ,  G01N21/55 ,  G01N21/8806 ,  G01N33/02 ,  G01N2201/0846

    Abstract: A food integrity probe design comprising two illumination fiber rings, allowing for two different simultaneous measurements wherein the inner illumination ring generates a surface reflectance signal on the central detection fibers and the outer illumination ring allows for an additional interactance measurement, probing deeper into the sample than the surface reflectance alone while partially eliminating specular reflection, which reduces the signal quality, through the addition of a ring-shaped diffusor onto the inner illumination ring is disclosed.

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