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公开(公告)号：US20230407373A1
公开(公告)日：2023-12-21
申请号：US18034908
申请日：2021-11-02
Inventor： V. Narry KIM , Sungyul LEE , Young-suk LEE
IPC: C12Q1/6816 , C12Q1/70
CPC classification number: C12Q1/6816 , C12Q1/701 , C12Q2600/136 , C12Q2600/158 , C12Y304/21004
Abstract: The present invention relates to an RNA interactome capturing protocol and an antiviral composition discovered using same. When used, the antiviral composition and pharmaceutical composition of the present invention can effectively inhibit viral infection and suppress viral proliferation in vivo after viral infection.
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公开(公告)号：US20230272057A1
公开(公告)日：2023-08-31
申请号：US18045964
申请日：2022-10-12
Inventor： Gou Young Koh , Jeomil Bae , Mi Jeong Kim , Jin-Sung Park , Su Jin Seo , Jaeryung Kim , Jang Ryul Park , Pilhan Kim , Wangyuhl Oh
IPC: C07K16/22 , A61P35/00 , A61K39/395 , A61K45/06
CPC classification number: C07K16/22 , A61P35/00 , A61K39/3955 , A61K45/06 , A61K2039/505
Abstract: The present invention relates to mouse antibodies that bind to angiopoietin-2 (Ang2), humanized anti-Ang2 antibodies derived therefrom, and the use thereof. The anti-Ang2 antibodies have a dual function of activating the Tie2 receptor together with neutralizing Ang2. The anti-Ang2 antibodies show the property of normalizing abnormal and pathological blood vessels, and thus exhibits therapeutic efficacy against various diseases and disorders associated with abnormal blood vessels. The present invention further provides an angiogenesis inhibitor and a composition for treatment of diseases associated with abnormal Ang2 expression and Tie2 dysregulation, which comprise the antibody as an active ingredient, and a composition for diagnosing diseases associated with Ang2 inhibition and Tie2 activation, which comprises the antibody.
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233.发明公开公开(公告)号：US20230226604A1
公开(公告)日：2023-07-20
申请号：US17997879
申请日：2021-05-07
Inventor： Taeghwan HYEON , Yung-Eun SUNG , Tae Yong YOO , Ji Mun YOO
CPC classification number: B22F1/054 , B22F1/142 , B01J35/0013 , B01J23/8906 , B01J37/088 , B22F1/16 , B01J21/18 , B01J37/32 , B22F2301/35
Abstract: Alloy nanoparticles, and a method for forming the alloy nanoparticles, an alloy nanocatalyst comprising the alloy nanoparticles are provided. The alloy nanoparticles are formed by a method comprising mixing a first metal complex including a first metal and a second metal complex including a second metal to form a multimetal compound and heat-treating the multimetal compound to form an alloy compound. The first metal and the second metal comprise transition metal, the first metal complex comprises a pyridine-based ligand, and a carbon shell containing N is formed on the surface of the alloy compound by the heat treatment.
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公开(公告)号：US20230175122A1
公开(公告)日：2023-06-08
申请号：US18047970
申请日：2022-10-19
Inventor： Jungwon PARK , Jihoon KIM
IPC: C23C16/30 , C23C16/02 , C23C16/458 , C23C16/46
CPC classification number: C23C16/305 , C23C16/0272 , C23C16/4582 , C23C16/46
Abstract: A compound structure and a forming method thereof are provided. The method of forming a compound structure according to embodiments of the present invention comprises loading a metal precursor on a substrate, providing a chalcogen precursor to the substrate, and reacting the chalcogen precursor with the metal precursor. The compound structure according to embodiments of the present invention is formed by the method and has a 2-dimensional structure.
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公开(公告)号：US20230096378A1
公开(公告)日：2023-03-30
申请号：US17911018
申请日：2021-03-12
Inventor： Kyungjae MYUNG , Taejoon KWON , In-Joon BAEK , Jae Sun RA , Yong Hwan PARK , Woojae JUNG , Daniyar OTARBAYEV , Seungwoo CHO
IPC: A61K48/00 , A61K31/7105 , A61K38/46 , A61P35/00 , C12N15/86
Abstract: The present invention relates to at least one delivery vehicle comprising: either a plurality of cleavaging agents that specifically recognize a plurality of nucleic acid sequences including unique sequences, which do not exist in normal cells, among variant region sequences specific for cells having genomic sequence variation in the cells having genomic sequence variation, or polynucleotides encoding the cleavaging agents; and a nuclease or a polynucleotide encoding the nuclease. The present invention also relates to a composition containing the delivery vehicle, and a method of inducing apoptosis of cells having genomic sequence variation by using the delivery vehicle or the composition.
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Patent Agency Ranking
236.发明申请公开(公告)号：US20220381695A1
公开(公告)日：2022-12-01
申请号：US17772305
申请日：2020-10-12
Inventor： Won-Shik CHOI , Seok-Chan YOON , Ho-Jun LEE
Abstract: A focus scan type imaging device for imaging a target object in a sample that induces aberration proposed. The device includes: a light source unit for emitting a beam; an optical interferometer for splitting the beam emitted from the light source into a sample wave and a reference wave, and providing an interference wave formed by interference between a reflection wave that is the sample wave reflected from the sample and the reference wave; a camera module for imaging the interference wave; a scanning mirror disposed on an optical path of the sample wave of the optical interferometer and configured to reflect the sample wave to cause the sample wave to scan the sample; a wavefront shaping modulator disposed on the optical path of the sample wave of the optical interferometer; and an imaging controller configured to operate in a phase map calculation mode and in an imaging mode.
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公开(公告)号：US11491327B2
公开(公告)日：2022-11-08
申请号：US16643429
申请日：2018-09-04
Inventor： Daehyeong Kim , Taeghwan Hyeon , Suji Choi , Sangihn Han , Dongjun Jung
Abstract: A bio electrode and a method of forming the same are provided. The bio electrode comprises a first core-shell nanowire/polymer composite comprising a first core-shell nanowire and a first polymer. The method of forming a bio electrode comprises a step of forming a core-shell nanowire by carrying out epitaxial growth of a biocompatible metal on a surface of a core comprising a conductive metal.
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公开(公告)号：US11437616B2
公开(公告)日：2022-09-06
申请号：US16352334
申请日：2019-03-13
Inventor： Hee Cheul Choi , Hyungki Kim
IPC: H01M4/38 , C22C28/00 , C22F1/16 , H01M10/0525 , H01M4/134
Abstract: The disclosure describes a nanowire for an anode material of a lithium ion cell and a method of preparing the same. The nanowire includes silicon (Si) and germanium (Ge). The nanowire has a content of the silicon (Si) higher than a content of the germanium (Ge) at a surface thereof, and has the content of germanium (Ge) higher than the content of the silicon (Si) at an inner part thereof.
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公开(公告)号：US20220257964A1
公开(公告)日：2022-08-18
申请号：US17674753
申请日：2022-02-17
Inventor： Jin Woo CHEON , Jae Hyun LEE , Jung Uk LEE
Abstract: The system for modulating the activity of cells according to an exemplary embodiment of the present invention may include a rotating magnetic field generating device which has an internal space in which a magnetic force generating unit and a living body can be disposed and forms a rotating magnetic field which satisfies Relationship Formulas 1 and 2 below; and magnetic particles disposed in the living body and capable of binding to a bioactive material and generating a torque when a rotating magnetic field is applied to transmit the torque to the bioactive material. |Mc|≥1 mT [Relationship Formula 1] |M75−Mc|/D75≤5.0 T/m [Relationship Formula 2] In Relationship Formulas 1 and 2 above, Mc is the strength of the magnetic field at the position of the rotation axis, D75 is the distance from the rotation axis to the 75% position of the distance to the magnetic force generating unit, and M75 is the strength of the magnetic field at the position D75.
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240.发明授权公开(公告)号：US11417516B2
公开(公告)日：2022-08-16
申请号：US16225432
申请日：2018-12-19
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , INSTITUTE FOR BASIC SCIENCE , ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Seong Keun Kim , Woo Chui Lee , Sang Tae Kim , Hyun Cheol Song , Seung Hyub Baek , Ji Won Choi , Jin Sang Kim , Chong Yun Kang , Christopher W. Bielawski , Jung Hwan Yum , Eric S. Larsen
IPC: C01F3/02 , H01L21/02 , H01L27/108 , H01L49/02
Abstract: Provided is a dielectric layer that has a rock salt structure in a room temperature stable phase. The dielectric layer is made of a compound having a chemical formula of BexM1-xO, where M includes one of alkaline earth metals and x has a value greater than 0 and not greater than 0.19. A semiconductor memory device also is provided that includes a capacitor composed of a lower electrode; a dielectric layer disposed on the lower electrode; and an upper electrode disposed on the dielectric layer, wherein the dielectric layer has a rocksalt structure in a room temperature stable phase and is made of a compound having a chemical formula shown below, BexM1-xO, where M comprises an alkaline earth metal and x has a value greater than 0 and not greater than 0.19.
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