公开(公告)号：US20160245830A1

公开(公告)日：2016-08-25

申请号：US14902075

申请日：2014-07-16

Applicant: PALO ALTO HEALTH SCIENCES, INC.

Inventor： Leslie E. MACE ,  Elizabeth K. SIEGELMAN ,  Debra L. REISENTHEL ,  Simon W.H. THOMAS

IPC: G01N33/84 ,  A61M21/02 ,  G01N21/78

CPC classification number: G01N33/84 ,  A61B5/0075 ,  A61B5/0816 ,  A61B5/082 ,  A61B5/0836 ,  A61B5/097 ,  A61B5/1032 ,  A61B5/4836 ,  A61B5/486 ,  A61B5/7415 ,  A61B2560/0223 ,  A61M16/0051 ,  A61M16/024 ,  A61M21/02 ,  A61M2021/0027 ,  A61M2021/0088 ,  A61M2205/3303 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2230/432 ,  G01N21/3151 ,  G01N21/78 ,  G01N21/783 ,  G01N2021/7773 ,  G01N2201/0231 ,  G01N2201/062 ,  G01N2201/1211 ,  G16H20/30 ,  G16H20/40 ,  G16H40/40 ,  G16H40/63 ,  G16H40/67 ,  G16H50/20 ,  H04M1/7253

Abstract: Quantitative colorimetric carbon dioxide detection and measurement systems are disclosed. The systems can include a gas conduit, a colorimetric indicator adapted to exhibit a color change in response to exposure to carbon dioxide gas, a temperature controller operatively coupled to the colorimetric indicator and configured to control the temperature of the colorimetric indicator, an electro-optical sensor assembly including a light source or sources adapted to transmit light to the colorimetric indicator, and a photodiode or photodiodes configured to detect light reflected from the colorimetric indicator and to generate a measurement signal, and a processor in communication with the electro-optical sensor assembly. The processor can be configured to receive the measurement signal generated by the electro-optical sensor assembly and to compute a concentration of carbon dioxide based on the measurement signal. Methods for using the systems are also disclosed including providing a breathing therapy to a patient or user.

Abstract translation: 公开了定量比色二氧化碳检测和测量系统。 所述系统可以包括气体导管，适于显示响应于暴露于二氧化碳气体的颜色变化的比色指示器，温度控制器，其可操作地耦合到比色指示器并且被配置为控制比色指示器的温度，电光学 传感器组件，包括适于将光传输到比色指示器的光源或光源;以及光电二极管或光电二极管，被配置为检测从比色指示器反射的光并产生测量信号;以及处理器，其与电光传感器组件 。 处理器可以被配置为接收由电光传感器组件产生的测量信号，并且基于测量信号计算二氧化碳的浓度。 还公开了使用该系统的方法，包括向患者或用户提供呼吸治疗。

公开(公告)号：US20160216288A1

公开(公告)日：2016-07-28

申请号：US14744778

申请日：2015-06-19

Applicant: H2Optx Inc.

Inventor： Rudolf J. Hofmeister ,  Donald A. Ice ,  Scott W. Tandy

IPC: G01N35/10 ,  G01N21/01 ,  G01N23/00

CPC classification number: G01J3/42 ,  B01D46/0002 ,  B01D46/42 ,  G01J3/00 ,  G01J3/0267 ,  G01J3/0291 ,  G01J3/06 ,  G01J3/10 ,  G01J3/44 ,  G01N1/06 ,  G01N21/01 ,  G01N21/25 ,  G01N21/253 ,  G01N21/33 ,  G01N21/3504 ,  G01N21/3577 ,  G01N21/65 ,  G01N23/00 ,  G01N33/15 ,  G01N35/10 ,  G01N2021/0106 ,  G01N2201/0231

Abstract: In some aspects, a device for apportioning granular samples includes a sample feeder defining a conduit, the conduit including a first opening to receive the granular samples and a second opening. The device includes a shuttle operably coupled to the sample feeder to receive the granular samples from the conduit via the second opening. The shuttle is configured to apportion the granular samples to incrementally enter a sample chamber to be analyzed. The device includes an outlet conduit fluidly coupled to the sample chamber and configured to permit the sample chamber to be evacuated.

Abstract translation: 在一些方面，用于分配颗粒样品的装置包括限定导管的样品进料器，所述导管包括用于接收颗粒样品的第一开口和第二开口。 该装置包括可操作地连接到样品供给器的穿梭器，以经由第二开口从导管接收颗粒样品。 梭子被配置成分配颗粒样品以递增地进入待分析的样品室。 该装置包括流体耦合到样品室并被配置为允许样品室被排空的出口导管。

公开(公告)号：US09354167B2

公开(公告)日：2016-05-31

申请号：US14507979

申请日：2014-10-07

Applicant: Vivian Hoi Nga Yuen ,  Edmund K H Woo ,  Gordon S Y Chiu

Inventor： Vivian Hoi Nga Yuen ,  Edmund K H Woo ,  Gordon S Y Chiu

IPC: G01N21/00 ,  G01N21/51 ,  G01N21/03 ,  G01N21/84

CPC classification number: G01N21/51 ,  G01N15/1434 ,  G01N15/1463 ,  G01N21/0332 ,  G01N21/15 ,  G01N21/84 ,  G01N25/02 ,  G01N33/2811 ,  G01N2015/0092 ,  G01N2021/151 ,  G01N2021/1761 ,  G01N2021/513 ,  G01N2201/0231 ,  G01N2201/0233

Abstract: An apparatus and method for the measurement of wax appearance temperature and wax disappearance temperature. The apparatus includes the following. The sample receptacle having a receptacle opening, including a bottom, at least one side and an open top. The sample receptacle including an inlet and an outlet for sample insertion and removal. The at least one side about the receptacle opening being light absorbing. The sample receptacle including a transparent cover mounted over the open top. The bottom of the receptacle opening having a reflective upper surface. A thermo device temperature change of the sample. A thermometer to register current temperature of the sample. A viewing chamber above the transparent cover, where the viewing chamber is surrounded by material that is light absorbing. A light emitting device to project light through the viewing chamber and the transparent cover.

Abstract translation: 用于测量蜡外观温度和蜡消失温度的装置和方法。 该装置包括以下装置。 样品容器具有容器开口，包括底部，至少一侧和敞开的顶部。 样品容器包括用于样品插入和取出的入口和出口。 围绕容器开口的至少一侧是光吸收。 样品容器包括安装在开口顶部上的透明盖。 容器开口的底部具有反射的上表面。 样品的热敏元件温度变化。 用于记录样品当前温度的温度计。 在透明盖上方的观察室，其中观察室由吸光材料包围。 一种用于通过观察室和透明盖突出光的发光装置。

公开(公告)号：US09228933B2

公开(公告)日：2016-01-05

申请号：US12624399

申请日：2009-11-23

Applicant: Victor Joseph ,  Amjad Huda ,  Alnoor Shivji ,  Jie Zhou

Inventor： Victor Joseph ,  Amjad Huda ,  Alnoor Shivji ,  Jie Zhou

IPC: C12M1/00 ,  C12M3/00 ,  C12M1/34 ,  G01N21/03 ,  B01L3/00 ,  B82Y30/00 ,  C12Q1/68 ,  G01N35/00 ,  B01L7/00 ,  G01N21/64 ,  G01N21/76 ,  G01N35/04

CPC classification number: C12Q1/686 ,  B01L3/50851 ,  B01L3/50853 ,  B01L7/52 ,  B01L7/54 ,  B01L2200/0689 ,  B01L2300/044 ,  B01L2300/0636 ,  B01L2300/0654 ,  B01L2300/0819 ,  B01L2300/0829 ,  B01L2300/18 ,  B01L2300/1822 ,  B01L2300/1827 ,  B82Y30/00 ,  C12Q1/6806 ,  C12Q1/6844 ,  G01N21/01 ,  G01N21/0332 ,  G01N21/6408 ,  G01N21/6452 ,  G01N21/76 ,  G01N35/0099 ,  G01N2021/6417 ,  G01N2021/6484 ,  G01N2035/0405 ,  G01N2201/0231 ,  H01L27/1443 ,  H01L31/0203 ,  H01L31/02325 ,  H01L31/024 ,  H01L31/105 ,  H01L31/18 ,  C12Q2565/501

Abstract: The present invention provides miniaturized instruments for conducting chemical reactions where control of the reaction temperature is desired or required. Specifically, this invention provides chips and optical systems for performing and monitoring temperature-dependent chemical reactions. The apparatus and methods embodied in the present invention are particularly useful for high-throughput and low-cost amplification of nucleic acids.

公开(公告)号：US09194793B2

公开(公告)日：2015-11-24

申请号：US13002664

申请日：2009-07-30

Applicant: Sakuichiro Adachi ,  Kunio Harada ,  Isao Yamazaki ,  Masaharu Kiyama ,  Takeshi Fujita

Inventor： Sakuichiro Adachi ,  Kunio Harada ,  Isao Yamazaki ,  Masaharu Kiyama ,  Takeshi Fujita

IPC: G01N21/59 ,  G01N21/25 ,  G01N35/02 ,  G01N21/03 ,  G01N35/00 ,  G01N35/04

CPC classification number: G01N21/253 ,  G01N21/0332 ,  G01N21/255 ,  G01N35/025 ,  G01N2035/00386 ,  G01N2035/0455 ,  G01N2201/0231 ,  G01N2201/0415 ,  G01N2201/0453 ,  G01N2201/0624 ,  G01N2201/0627

Abstract: Using an LED element as a light source, a photometric unit including the light source, a light receiving element and other components therebetween is reduced in size. A holder 30 detachable from the device as a unit holds a light emission unit 15 formed of an LED and a light receiving element 21, and the holder is placed inside a thermostatic chamber 18 which holds a constant temperature fluid 17. Thus, the photometric unit is reduced in size.

Abstract translation: 使用LED元件作为光源，包括光源，光接收元件和其间的其它部件的光度单元的尺寸减小。 从装置作为一个单元可拆卸的保持器30保持由LED和光接收元件21形成的发光单元15，并且保持器放置在保持恒温流体17的恒温室18内部。因此，测光单元 尺寸减小。

公开(公告)号：US09188510B2

公开(公告)日：2015-11-17

申请号：US13623877

申请日：2012-09-21

Applicant: Jeffrey Haas ,  Douglas Haas

Inventor： Jeffrey Haas ,  Douglas Haas

IPC: G01N21/75 ,  G01N1/02 ,  G01N35/00 ,  G01N21/78 ,  G01N25/00 ,  G01N33/22 ,  G01N33/94

CPC classification number: G01N1/02 ,  G01N21/78 ,  G01N25/00 ,  G01N33/22 ,  G01N33/227 ,  G01N33/94 ,  G01N35/00009 ,  G01N35/00722 ,  G01N2001/022 ,  G01N2001/028 ,  G01N2035/00425 ,  G01N2035/0091 ,  G01N2035/0097 ,  G01N2201/0231 ,  Y10T436/25375

Abstract: A portable chemical analytical apparatus to analyze a test swipe having a base; a chemically treated pad containing the swiped sample positioned in a white zone above the base; and a tab attached to one side of the base. The apparatus includes a heater to warm the test swipe to a predetermined temperature; a clamp to secure the test swipe to the heater; one or more pumps to dispense one or more chemicals onto the test swipe from a disposable cartridge; a fan to remove chemical vapors rising a predetermined distance from the test swipe; and a camera to capture an image of the test swipe for un-biased automated analysis, and displayed on an LCD screen.

Abstract translation: 一种用于分析具有基底的测试滑动的便携式化学分析装置; 化学处理的垫，其包含位于基底上方的白色区域中的被擦拭的样品; 以及附接到基座的一侧的突片。 该装置包括加热器，以将测试滑动加热至预定温度; 用于将测试滑动固定到加热器的夹具; 一个或多个泵将一种或多种化学品从一次性药筒分配到测试刷卡上; 用于去除从测试滑动上升预定距离的化学气体的风扇; 以及相机捕获测试滑动的图像以进行无偏压的自动分析，并显示在LCD屏幕上。

公开(公告)号：US20150211995A1

公开(公告)日：2015-07-30

申请号：US14677170

申请日：2015-04-02

Applicant: SYSMEX CORPORATION

Inventor： Norimasa YAMAMOTO ,  Takashi YAMATO ,  Naohiko MATSUO ,  Satoshi IGUCHI

IPC: G01N21/59 ,  G01N21/31 ,  G01N21/03

CPC classification number: G01N35/00594 ,  G01N21/0332 ,  G01N21/17 ,  G01N21/31 ,  G01N21/59 ,  G01N33/5302 ,  G01N33/86 ,  G01N35/00603 ,  G01N35/025 ,  G01N2035/00465 ,  G01N2201/0231 ,  G01N2201/062 ,  Y10S436/815 ,  Y10S436/817 ,  Y10T436/11 ,  Y10T436/112499 ,  Y10T436/113332 ,  Y10T436/146666

Abstract: A specimen analyzing method and a specimen analyzing apparatus capable of measuring interference substances before analyzing a specimen. The method comprises a step for sucking the specimen stored in a specimen container (150) and sampling it in a first container (153), a step for optically measuring the specimen in the first container, a step for sampling the specimen in a second container (154) and preparing a specimen for measurement by mixing the specimen with a reagent in the second container, and a step for analyzing the specimen for measurement according to the results of the optical measurement of the specimen.

Abstract translation: 一种能够在分析试样之前测量干扰物质的试样分析方法和试样分析装置。 该方法包括：将存储在样本容器（150）中的样本抽吸并在第一容器（153）中取样的步骤，用于光学测量第一容器中的样本的步骤，将第二容器 （154），并通过将试样与第二容器中的试剂混合来制备测量样本，以及根据样品的光学测量结果分析测量样本的步骤。

公开(公告)号：US20150176070A1

公开(公告)日：2015-06-25

申请号：US14414235

申请日：2013-07-11

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Yuichiro Ota ,  Tomohiro Shoji ,  Michiru Fujioka ,  Takanobu Haga

IPC: C12Q1/68 ,  G01N21/03 ,  G01N15/14 ,  G01N21/64

CPC classification number: C12Q1/6869 ,  G01N15/1436 ,  G01N15/1459 ,  G01N15/1484 ,  G01N21/0332 ,  G01N21/05 ,  G01N21/6428 ,  G01N21/645 ,  G01N33/5436 ,  G01N2015/0038 ,  G01N2015/1006 ,  G01N2021/6482 ,  G01N2201/0231 ,  G01N2201/061

Abstract: In a biomaterial analysis, erroneous detection of a particle emitting fluorescence is prevented, and highly sensitive and highly accurate optical detection in biomaterial analysis is performed. A flow cell (104) for biomaterial analysis includes: a light-transmissive upper substrate (310); an antireflective lower substrate (313); and an inner layer section interposed between the upper substrate (310) and the lower substrate (313) and including a flow path (311) in which a particle (312) configured to emit fluorescence is provided. A biomaterial analysis device includes: a flow cell (104) for biomaterial analysis as described above; and an irradiation unit configured to irradiate excitation light; and an optical detection unit (106) configured to detect fluorescence emitted by the particle (312).

Abstract translation: 在生物材料分析中，防止发射荧光的颗粒的错误检测，并且进行生物材料分析中的高灵敏度和高精度的光学检测。 用于生物材料分析的流动池（104）包括：透光上基板（310）; 抗反射下基板（313）; 以及插入在上基板（310）和下基板（313）之间的内层部分，并且包括设置有发射荧光的颗粒（312）的流路（311）。 生物材料分析装置包括：如上所述的用于生物材料分析的流动池（104）; 以及被配置为照射激发光的照射单元; 以及被配置为检测由所述粒子（312）发射的荧光的光学检测单元（106）。

公开(公告)号：US08545760B2

公开(公告)日：2013-10-01

申请号：US11905328

申请日：2007-09-28

Applicant: Norimasa Yamamoto ,  Takashi Yamato ,  Naohiko Matsuo ,  Satoshi Iguchi

Inventor： Norimasa Yamamoto ,  Takashi Yamato ,  Naohiko Matsuo ,  Satoshi Iguchi

IPC: G01N21/00

CPC classification number: G01N35/00594 ,  G01N21/0332 ,  G01N21/17 ,  G01N21/31 ,  G01N21/59 ,  G01N33/5302 ,  G01N33/86 ,  G01N35/00603 ,  G01N35/025 ,  G01N2035/00465 ,  G01N2201/0231 ,  G01N2201/062 ,  Y10S436/815 ,  Y10S436/817 ,  Y10T436/11 ,  Y10T436/112499 ,  Y10T436/113332 ,  Y10T436/146666

Abstract: A specimen analyzing method and a specimen analyzing apparatus capable of measuring interference substances before analyzing a specimen. The method comprises a step for sucking the specimen stored in a specimen container (150) and sampling it in a first container (153), a step for optically measuring the specimen in the first container, a step for sampling the specimen in a second container (154) and preparing a specimen for measurement by mixing the specimen with a reagent in the second container, and a step for analyzing the specimen for measurement according to the results of the optical measurement of the specimen.

公开(公告)号：US20130062530A1

公开(公告)日：2013-03-14

申请号：US13228061

申请日：2011-09-08

Applicant: Yu Chih CHANG

Inventor： Yu Chih CHANG

IPC: G01J1/42 ,  H01J40/14

CPC classification number: G01N21/01 ,  G01N21/554 ,  G01N2201/0231

Abstract: A biochemical material detection system is provided, which is used to detect biochemical materials. A material to be detected is placed above a sensor module in the system. A light source is guided in by a light emitting device to measure a refractive index of the material to be detected or other parameters related to the material to be detected. Furthermore, a heat source generated by the light emitting device in the system is further isolated outside the sensor module, thereby preventing the heat source from influencing a sensed result to improve the accuracy of the sensed result.

Abstract translation: 提供生化材料检测系统，用于检测生化材料。 要检测的材料放置在系统中的传感器模块上方。 光源通过发光装置被引导以测量待检测材料的折射率或与待检测材料相关的其它参数。 此外，由系统中的发光器件产生的热源进一步隔离在传感器模块的外部，从而防止热源影响感测结果，以提高感测结果的精度。