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    Dual containment system for transferring sterile fluids to and from a container
    241.
    发明授权
    Dual containment system for transferring sterile fluids to and from a container 失效
    用于将无菌流体输送到容器的双重密封系统

    公开(公告)号：US5687993A

    公开(公告)日：1997-11-18

    申请号：US331696

    申请日：1994-10-31

    Applicant: Larry H. Brim

    Inventor： Larry H. Brim

    IPC: F16L39/02 ,  F16L39/00 ,  F16L47/00

    CPC classification number: F16L39/02 ,  F16L2201/44

    Abstract: A dual containment system is taught for adding sterile or caustic chemical, pharmaceutical, and biological fluids to and withdrawing them from a container. Included is a dual containment enabling fitting having a set of small diameter barbs at each end of a hollow conduit and a set of enlarged inner barbs at each end of a raised portion at the center of the hollow conduit. A port plate with a barbed spout is affixed to an aperture on the container. Also included is a dip tube with one end attached to a small diameter barb on the fitting and the other end extending into the container through the port plate spout. A connecting sheath encompasses the external portion of the dip tube and is attached at one end to a large diameter barb on the fitting and at the other end to the barbed spout. This creates a secondary containment chamber between the dip tube and the connecting sheath. The fitting may also be connected in series with a distal similarly functioning fitting creating a secondary containment chamber that allows the dual containment transfer of fluids. The secondary containment chamber prevents leakage and contamination and may be used for coaxial fluid flow, to effect a gas exchange with the fluid contents, and to cool or heat the fluid.

    Abstract translation: 教导了一种双重遏制系统，用于将无菌或苛性化学，制药和生物流体加入容器中并将其从容器中取出。 包括双重容纳配件，其能够在中空导管的每个端部处具有一组小直径倒钩，并且在中空导管的中心处的凸起部分的每个端部处具有一组放大的内倒钩。 具有倒刺喷嘴的端口板固定在容器上的孔上。 还包括一个汲取管，其一端附接到配件上的小直径倒钩，另一端通过端口板喷口延伸到容器中。 连接护套包围汲取管的外部部分，并且在一端附接到配件上的大直径倒钩上，另一端连接到有倒钩的喷口。 这在汲取管和连接护套之间产生二次容纳室。 配件还可以与远程类似功能的配件串联连接，从而形成允许流体的双重容纳传递的二级容纳室。 次级容纳室防止泄漏和污染，并且可以用于同轴流体流动，以与流体内容物进行气体交换，并且冷却或加热流体。

    Fluid connectors
    242.
    发明授权
    Fluid connectors 失效
    流体连接器

    公开(公告)号：US4022205A

    公开(公告)日：1977-05-10

    申请号：US412553

    申请日：1973-11-05

    Applicant: Francis J. Tenczar

    Inventor： Francis J. Tenczar

    IPC: F16L29/00 ,  A61M39/02 ,  A61M39/14 ,  F16L37/02 ,  F16L37/30 ,  A61M5/00 ,  F16L47/00

    CPC classification number: A61M39/14 ,  F16L37/02 ,  F16L37/30 ,  A61M2039/1027 ,  F16L2201/44 ,  Y10S285/901 ,  Y10S285/915 ,  Y10S604/905 ,  Y10T29/49833

    Abstract: A connector means for conveying fluid from a supply source to a delivery location, said connectors having one conduit extending to the supply source and another conduit extending to the delivery location. Each terminal part has a cylindrical housing with a closed end to which the conduit is joined, and having an opposite operable end which is closed by a penetrable barrier. The barrier and closed end of the housing define an interior environment safe from external contaminants. A male tubular coupler is in one housing, a female tubular coupler is in the other housing, and a penetrator element is disposed around one of the tubular connectors. The penetrable barriers have a film of covered adhesive. The exposed adhesive films are placed in face to face contact to coaxially align the housing parts and bond the barrier membranes to exclude the environment. The penetrator element pierces the adhering barriers by either moving the penetrator element from one housing into the coaxially aligned housing, or by telescoping the housing cylinders so that the adhering barriers are contacted by the fixed penetrator element. The male tubular connector then engages the female tubular connector within a protected environment to effect connection between the supply source and the delivery location.

    Abstract translation: 一种用于将流体从供应源输送到输送位置的连接器装置，所述连接器具有延伸到供应源的一个导管和延伸到输送位置的另一导管。 每个端子部分具有圆柱形壳体，其具有封闭端，导管连接到该封闭端，并且具有由可穿透屏障封闭的相对的可操作端。 外壳的屏障和封闭端限定了外部污染物的内部环境。 一个外壳中的一个公管耦合器，另一个壳体中有一个阴管耦合器，一个管状连接器周围设有穿透元件。 可穿透的屏障具有覆盖粘合剂的薄膜。 暴露的粘合剂膜被放置成面对面接触以同轴地对准壳体部分并结合阻隔膜以排除环境。 穿透元件通过将穿透元件从一个壳体移动到同轴对准的外壳中，或者通过使壳体圆柱体伸缩使得粘附的屏障被固定的穿透元件接触来刺穿粘附的屏障。 然后，公形管状连接器在受保护环境内接合母管状连接器，以实现供应源和输送位置之间的连接。

    Aseptic joints
    243.
    发明授权
    Aseptic joints 失效
    ASEPTIC JOINTS

    公开(公告)号：US3563571A

    公开(公告)日：1971-02-16

    申请号：US3563571D

    申请日：1969-07-09

    Applicant: LADISH CO

    Inventor： WERRA BRUNO H

    IPC: F16L23/10 ,  F16L23/16 ,  F16L53/00

    CPC classification number: F16L23/16 ,  F16L23/10 ,  F16L2201/44

    Abstract: An aseptic joint has a sealing gasket interposed between the flanges of two pipe ends, there being a rubber ring around the gasket to form an annular steam chamber between the rubber ring and the OD of the gasket, and there being means including a steam inlet and outlet nipple with a dam between for continuously circulating steam throughout the length of the steam chamber. A clamping ring acts on the flanges of the two pipe ends to engage the gasket and rubber ring therebetween, the clamping ring having a slot through which the steam nipple projects.

    Aseptic coupling devices
    246.
    发明授权
    Aseptic coupling devices 有权

    公开(公告)号：US12042621B2

    公开(公告)日：2024-07-23

    申请号：US17838436

    申请日：2022-06-13

    Applicant: Colder Products Company

    Inventor： Jeremy Henry Nichols ,  Blair D. Plackner ,  Loi T. Truong ,  Randall Scott Williams

    IPC: A61M39/18 ,  A61M39/10 ,  A61M39/16 ,  F16L37/098 ,  F16L37/30

    CPC classification number: A61M39/18 ,  A61M39/10 ,  A61M39/165 ,  F16L37/098 ,  F16L37/30 ,  F16L2201/10 ,  F16L2201/44 ,  F16L2201/80

    Abstract: An aseptic coupling arrangement can include a first coupling device and a second aseptic coupling device. In one embodiment, the first and second coupling devices are substantially similar, each having a main body defining a front face and a fluid passageway therethrough. A first connecting feature disposed on the main body of each coupling device may be provided for aligning and coupling the aseptic devices together. Each coupling device may also include a sealing member received in the main body and a membrane removably coupled to the main body front face to cover the sealing member. The first aseptic coupling device may also include a rotatable protective cover that is removably attached to the main body and connected to the membrane. In one embodiment, the removal of the protective covers away from two coupled main bodies, in a direction parallel to the front faces, causes removal of the membranes.

    ASEPTIC CONNECT AND DISCONNECT COUPLER
    248.
    发明公开
    ASEPTIC CONNECT AND DISCONNECT COUPLER 审中-公开

    公开(公告)号：US20240084937A1

    公开(公告)日：2024-03-14

    申请号：US18238793

    申请日：2023-08-28

    Applicant: Avantor Fluid Handling LLC

    Inventor： Tat M. Yuen

    IPC: F16L29/00

    CPC classification number: F16L29/002 ,  F16L29/007 ,  F16L2201/44

    Abstract: A coupler for aseptically coupling and controlling fluid communication between at least two components. The coupler includes a first connector housing with an inner concave surface. A first connector extends from the top of the first connector housing and is adapted to connect to a first component. A first connector conduit extends through the first connector and into the first connector housing so as to define a fluid passageway to an inner opening on the inner surface of the first connector housing. A rotary valve is located within an inner cavity of the first connector housing and includes at least two rotary valve segments. The rotary valve segments are configured to rotate within the cavity. At least one of the rotary valve segments includes a fluid conduit extending through the at least one rotary valve segment.

    ASEPTIC FLUID COUPLINGS
    249.
    发明公开
    ASEPTIC FLUID COUPLINGS 审中-公开

    公开(公告)号：US20230375116A1

    公开(公告)日：2023-11-23

    申请号：US18200118

    申请日：2023-05-22

    Applicant: Colder Products Company

    Inventor： Jack T. Stangl ,  Loi T. Truong

    IPC: F16L37/32

    CPC classification number: F16L37/32 ,  F16L2201/44

    Abstract: Some fluid coupling devices described herein are configured for use in fluid systems for purposes of providing a single-use, aseptic disconnection functionality that substantially prevents fluid spillage when being disconnected. In some embodiments, the coupling portions cannot be functionally reconnected to each other after being disconnected from each other.

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