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公开(公告)号：CZ9900619A3
公开(公告)日：2000-02-16
申请号：CZ61999
申请日：1997-09-02
Applicant: BASF AG
Inventor： AMBERG WILHELM , JANSEN ROLF , KLING ANDREAS , KLINGE DAGMAR , RIECHERS HARTMUT , HERGENROEDER STEFAN , RASCHACK MANFRED , UNGER LILIANE
IPC: A61K31/505 , A61P9/12 , C07D237/22 , C07D239/34 , C07D239/60 , C07D239/70 , C07D491/04
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公开(公告)号：CZ9803261A3
公开(公告)日：2000-01-12
申请号：CZ326198
申请日：1997-04-04
Applicant: BASF AG
Inventor： AMBERG WILHEM , KLING ANDREAS , KLINGE DAGMAR , RIECHERS HARTMUT , BAUMANN ERNST , UNGER LILIANE , RASCHACK MANFRED , HERGENROEDER STEFAN , SCHULT SABINE
IPC: A61K31/505 , A61P9/10 , A61P9/12 , C07D239/34 , C07D239/52 , C07D239/60 , C07D239/70 , C07D405/12
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公开(公告)号：CZ326298A3
公开(公告)日：2000-01-12
申请号：CZ326298
申请日：1997-04-04
Applicant: BASF AG
Inventor： AMBERG WILHEM , KLING ANDREAS , KLINGE DAGMAR , RIECHERS HARTMUT , BAUMANN ERNST , UNGER LILIANE , RASCHACK MANFRED , HERGENROEDER STEFAN , SCHULT SABINE
IPC: A61K31/505 , A61P9/00 , A61P13/08 , A61P13/12 , C07D215/22 , C07D239/34 , C07D239/60
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公开(公告)号：ZA9805277B
公开(公告)日：1999-12-20
申请号：ZA9805277
申请日：1998-06-18
Applicant: BASF AG
Inventor： AMBERG WILHELM , KLING ANDREAS , KLINGE DAGMAR , RIECHERS HARTMUT , HERGENROEDER STEFAN , RASCHACK MANFRED , UNGER LILIAN
IPC: C07D251/16 , A61K31/4965 , A61K31/50 , A61K31/505 , A61K31/517 , A61K31/519 , A61K31/53 , A61P7/02 , A61P9/02 , A61P9/04 , A61P9/10 , A61P9/12 , A61P11/06 , A61P13/08 , A61P13/12 , A61P25/06 , A61P35/00 , A61P35/04 , A61P43/00 , C07C247/12 , C07D213/68 , C07D237/14 , C07D237/16 , C07D239/34 , C07D239/52 , C07D239/56 , C07D239/60 , C07D239/70 , C07D239/80 , C07D239/95 , C07D241/18 , C07D251/22 , C07D251/34 , C07D251/52 , C07D253/06 , C07D403/12 , C07D491/048 , C07D , A61K , C07C
CPC classification number: C07D403/12 , C07C247/12 , C07D237/16 , C07D239/34 , C07D239/52 , C07D239/70 , C07D251/22
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公开(公告)号：NO996268D0
公开(公告)日：1999-12-17
申请号：NO996268
申请日：1999-12-17
Applicant: BASF AG
Inventor： AMBERG WILHELM , KLING ANDREAS , KLINGE DAGMAR , RIECHERS HARTMUT , HERGENROEDER STEFAN , RASCHACK MANFRED , UNGER LILIANE
IPC: C07D251/16 , A61K31/4965 , A61K31/50 , A61K31/505 , A61K31/517 , A61K31/519 , A61K31/53 , A61P7/02 , A61P9/02 , A61P9/04 , A61P9/10 , A61P9/12 , A61P11/06 , A61P13/08 , A61P13/12 , A61P25/06 , A61P35/00 , A61P35/04 , A61P43/00 , C07C247/12 , C07D213/68 , C07D237/14 , C07D237/16 , C07D239/34 , C07D239/52 , C07D239/56 , C07D239/60 , C07D239/70 , C07D239/80 , C07D239/95 , C07D241/18 , C07D251/22 , C07D251/34 , C07D251/52 , C07D253/06 , C07D403/12 , C07D491/048 , C07D
Abstract: The invention relates to carboxylic acid derivatives of formula (I) wherein the constituents have the meaning given in the description. The invention also relates to the production of said derivatives, and to their use as endothelin receptor antagonists.
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Patent Agency Ranking
公开(公告)号：BG102770A
公开(公告)日：1999-11-30
申请号：BG10277098
申请日：1998-09-15
Applicant: BASF AG
Inventor： AMBERG WILHELM , KLING ANDREAS , KLINGE DAGMAR , RIECHERS HARTMUT , BAUMANN ERNST , UNGER LILIANE , RASCHACK MANFRED , HERGENRODER STEFAN , SCHULT SABINE
IPC: A61K31/00 , A61K31/47 , A61K31/505 , A61P9/00 , A61P9/12 , A61P13/00 , A61P13/12 , C07D215/22 , C07D215/227 , C07D239/34 , C07D239/60 , C07D401/12 , C07D403/12
Abstract: The invention relates to derivatives of caboxylic acids withthe formulawhere the radicals have the meanings listed in the descriptionwell as to their preparation and to application as medicamentousforms.10 claims
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公开(公告)号：SK25999A3
公开(公告)日：1999-09-10
申请号：SK25999
申请日：1997-09-02
Applicant: BASF AG
Inventor： AMBERG WILHELM , JANSEN ROLF , KLING ANDREAS , KLINGE DAGMAR , RIECHERS HARTMUT , HERGENRODER STEFAN , RASCHACK MANFRED , UNGER LILIANE
IPC: A61K31/505 , A61K31/506 , A61K31/519 , A61P9/04 , A61P9/08 , A61P9/12 , A61P43/00 , C07C59/66 , C07C69/734 , C07D239/34 , C07D239/52 , C07D239/60 , C07D239/70 , C07D491/04 , C07D491/048
Abstract: The invention relates to carboxylic acid derivatives of the formula Iwhere the radicals have the meanings stated in the description, and to their use as drugs.
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公开(公告)号：CA2322541A1
公开(公告)日：1999-09-10
申请号：CA2322541
申请日：1999-02-25
Applicant: BASF AG
Inventor： HERGENRODER STEFAN , RASCHACK MANFRED , RIECHERS HARTMUT , UNGER LILIANE , KLINGE DAGMAR , AMBERG WILHELM , JANSEN ROLF
IPC: C07D251/22 , A61K31/192 , A61K31/216 , A61K31/505 , A61K31/506 , A61K31/519 , A61K31/53 , A61P9/04 , A61P9/06 , A61P9/10 , A61P9/12 , A61P11/06 , A61P13/08 , A61P13/12 , A61P35/00 , A61P43/00 , C07C59/66 , C07C59/68 , C07C69/734 , C07D213/63 , C07D239/34 , C07D239/52 , C07D239/60 , C07D405/12 , C07D491/048 , C07D403/12 , C07D213/64
Abstract: The invention relates to carboxylic acid derivatives of formula (I), wherein R1-R6, Q, W, X, Y and Z have the meanings given in the description. The novel compounds are suitable for combating diseases.
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公开(公告)号：CA2321182A1
公开(公告)日：1999-08-26
申请号：CA2321182
申请日：1999-02-05
Applicant: BASF AG
Inventor： KLINGE DAGMAR , KLING ANDREAS , AMBERG WILHELM , UNGER LILIANE , RIECHERS HARTMUT , JANSEN ROLF , RASCHACK MANFRED , HERGENRODER STEFAN
IPC: A61K31/505 , A61K31/506 , A61P5/14 , A61P9/02 , A61P9/10 , A61P9/12 , A61P11/06 , A61P13/12 , A61P35/00 , A61P43/00 , C07D239/34 , C07D239/46 , C07D239/52 , C07D239/60 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07D239/36
Abstract: The invention relates to carboxylic acid derivatives of formula (I), wherein the substituents have the following meanings; R1= tetrazole or a group (1); R = a radical OR7(2), (3), a 5-membe red heteroaromatic bonded by a nitrogen atom such a pyrrolyl, pyrazolyl, imidazolyl and trizolyl; R2, R3 = hydrogen, hydroxy, NH2, NH(C1-C4-alkyl), N(C1-C4-alkyl)2, halogen, C1-C4-alkyl, C2-C4-alkenyl, C2-C4-alkinyl, C1-C4-hydroxyalkyl, C1-C4-alkoxy, C1-C4-halogen alkyl, C1-C4-alkoxy, C1-C4-halogen alkoxy or C1-C4-alkythio; X = halogen, C1-C4-halogen alkyl, hydroxy; R4 and R5 = phenyl or naphthyl, C3-C7-cycloalkyl, phenyl or naphthyl which are bonded in ortho position by a direct bond, a methylene, ethylene or ethenylene group, an oxygen or sulfur atom or an SO2-NH or an N-alkyl group or a 5-membered or 6-membered heteroaromatic; R6 = hydrogen, phenyl or naphthyl, a five or six-membered heteroaromatic, C1-C8-alkyl, C3-C6-alkenyl, C3-C6-alkinyl or C3-C8-cycloalkyl, whereby said radicals can be substituted once or many times, with the proviso that R6 can only stand for hydrogen if Z does not represent a single bond; Z = sulfur, oxygen or a single bond, in addition to the physiologically compatible salts and the enantiomeric-pure and diastereomeric-pure forms. The novel compounds are suitable for combating diseases, especially as endothelin antagonists.
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公开(公告)号：TR9900486T2
公开(公告)日：1999-06-21
申请号：TR9900486
申请日：1997-09-02
Applicant: BASF AG
Inventor： AMBERG WILHELM , JANSEN ROLF , KLING ANDREAS , KLINGE DAGMAR , RIECHERS HARTMUT , HERGENROEDER STEFAN , RASCHACK MANFRED , UNGER LILIANE
IPC: A61K31/505 , A61K31/506 , A61K31/519 , A61P9/04 , A61P9/08 , A61P9/12 , A61P43/00 , C07C59/66 , C07C69/734 , C07D239/34 , C07D239/52 , C07D239/60 , C07D239/70 , C07D491/04 , C07D491/048 , C07D237/52
CPC classification number: C07D239/70 , C07C59/66 , C07C69/734 , C07D239/34 , C07D239/52 , C07D239/60 , C07D491/04
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