画像処理装置、顕微鏡システム、内視鏡システム及び画像処理方法
    262.
    发明申请
    画像処理装置、顕微鏡システム、内視鏡システム及び画像処理方法 审中-公开
    图像处理装置,显微镜系统,内窥镜系统和图像处理方法

    公开(公告)号:WO2013187148A1

    公开(公告)日:2013-12-19

    申请号:PCT/JP2013/062648

    申请日:2013-04-30

    Inventor: 金子 善興

    Abstract:  染色を行うことなく取得された生体の観察画像に基づいて生体の異常等の判断を行うことができる画像処理装置、顕微鏡システム、及び画像処理方法を提供する。画像処理装置10は、腺管に励起光を照射し、該腺管から発生する蛍光を観察することにより取得された画像を表す画像情報を取得する画像取得部12と、画像情報に基づいて、蛍光の強度に対応する値として蛍光強度を算出する蛍光強度算出部151と、蛍光強度算出部151により算出された蛍光強度に基づいて、上記腺管の異常を判定する画像判定部152とを備える。

    Abstract translation: 提供了一种图像处理装置,显微镜系统和图像处理方法,其能够基于未染色的活体的观察图像来确定例如生物体的异常。 图像处理装置(10)包括:图像获取单元(12),用于获得表示通过用激发光照射腺体管并且通过观察从腺体管产生的荧光而获得的图像的图像信息; 荧光强度计算单元,基于所述图像信息,计算荧光强度作为与荧光强度对应的值; 以及基于由荧光强度计算部(151)计算出的荧光强度,确定腺体管道的异常的图像判定部(152)。

    乳房撮像装置
    263.
    发明申请
    乳房撮像装置 审中-公开
    妈妈设备

    公开(公告)号:WO2013080773A1

    公开(公告)日:2013-06-06

    申请号:PCT/JP2012/079120

    申请日:2012-11-09

    Abstract:  乳房撮像装置1は、被検者Aの乳房Bに光を照射し、拡散光を検出することにより乳房Bの内部情報を取得する装置であって、乳房Bを囲む容器3と、容器3の内側へ向けて取り付けられ光の照射及び検出を行う複数の光ファイバ11とを備える。容器3は、開口30aを有するベース部材30と、開口30aと連通して連続配置された複数の環状部材40と、ベース部材30から最も離れた環状部材40の内側に配置された底部部材50とを有する。各環状部材40及び底部部材50は、ベース部材30側に隣接する環状部材40若しくはベース部材30に対して相対的に連通方向に変位可能に構成されている。複数の光ファイバ11の少なくとも一部は、複数の環状部材40に取り付けられている。

    Abstract translation: 一种用光照射被检体(A)的乳房(B)的乳房照相装置(1),并且通过检测散射光来获取乳房(B)的内部的信息,包括:包围乳房的容器(3) B),以及多个光纤(11),其朝向容器(3)的内侧安装并进行照明和光的检测。 容器(3)还包括设置有开口(30a)的基部构件(30),与开口(30a)连通并且串联定位的多个环形构件(40)和底部构件 (50),其位于距离基部构件(30)最远的环状构件(40)的内侧。 每个环形构件(40)和底部构件(50)构造成在与基部构件(30)侧相邻的环形构件(40)的相对方向或基部 会员(30)。 所述多个光纤(11)的至少一部分被附接到所述多个环状部件(40)。

    APPARATUS AND METHOD FOR MEASURING AN ANALYTE SUCH AS BILIRUBIN, USING LIGHT
    264.
    发明申请
    APPARATUS AND METHOD FOR MEASURING AN ANALYTE SUCH AS BILIRUBIN, USING LIGHT 审中-公开
    用于测量分析物如BILIRUBIN的装置和方法,使用光

    公开(公告)号:WO2011148280A1

    公开(公告)日:2011-12-01

    申请号:PCT/IB2011/051856

    申请日:2011-04-27

    Abstract: An analyte measuring device (5) for monitoring, for example, levels of a tissue analyte (e.g., bilirubin), includes a number of narrow band light sources (10), each narrow band light source being structured to emit a spectrum of light covering a number of wavelengths, and a number of detector assemblies (15) configured to receive light reflected from the transcutaneous tissues of a subject. Each of the detector assemblies includes a filter (20) and a photodetector (25), each filter being structured to transmit a main transmission band and one or more transmission sidebands, wherein for each narrow band light source the spectrum thereof includes one or more wavelengths that fall within the transmission band of at least one of the filters, and wherein for each narrow band light source the spectrum thereof does not include any wavelengths that fall within the one or more transmission sidebands of any of the optical filters.

    Abstract translation: 用于监测例如组织分析物(例如,胆红素)的水平的分析物测量装置(5)包括多个窄带光源(10),每个窄带光源被构造成发射光谱覆盖 多个波长和多个检测器组件(15),其被配置为接收从受试者的经皮组织反射的光。 每个检测器组件包括滤波器(20)和光电检测器(25),每个滤波器被构造为传输主传输频带和一个或多个传输边带,其中对于每个窄带光源,其频谱包括一个或多个波长 其落在至少一个滤波器的传输频带内,并且其中对于每个窄带光源,其频谱不包括落入任何光学滤波器的一个或多个传输边带内的任何波长。

    IMAGING DEVICE AND METHOD FOR OPTOACOUSTIC IMAGING OF SMALL ANIMALS
    265.
    发明申请
    IMAGING DEVICE AND METHOD FOR OPTOACOUSTIC IMAGING OF SMALL ANIMALS 审中-公开
    小动物光学成像的成像装置和方法

    公开(公告)号:WO2011012274A1

    公开(公告)日:2011-02-03

    申请号:PCT/EP2010/004542

    申请日:2010-07-23

    Abstract: An imaging device (100) being configured for optoacoustic imaging of an object (1) comprises an illumination device (10) including optical components arranged for illuminating the object (1), a detector device (20) arranged for detecting acoustic signals created in the object (1), and a container device (50) including a tank (51) arranged for accommodating the detector device (20), the object (1) and a matching transmission medium (53), wherein the container device (50) further includes a holding device (55) being adapted for positioning and moving the object (1) relative to the illumination device (10) and the detector device (20), the optical components are arranged in the tank (51) for illuminating the object (1) from different directions, and the detector device (20) comprises an array (21) of detector elements (22) which is arranged in the tank (51). According to a preferred embodiment, the holding device comprises a membrane (55) arranged for accommodating the object (1), wherein the membrane separates the object (1) and the matching transmission medium (53) from each other. Furthermore, an imaging method of optoacoustic imaging of an object (1) using the imaging device (100) is described.

    Abstract translation: 被配置为用于物体(1)的光声成像的成像装置(100)包括照明装置(10),其包括布置成用于照射物体(1)的光学部件;检测器装置(20),被布置成用于检测在 物体(1)和容纳装置(50),其包括布置成容纳检测器装置(20)的容器(51),物体(1)和匹配传输介质(53),其中容器装置(50)进一步 包括适于相对于所述照明装置(10)和所述检测装置(20)定位和移动所述物体(1)的保持装置(55),所述光学部件布置在所述罐(51)中用于照亮所述物体 检测器装置(20)包括布置在罐(51)中的检测器元件(22)的阵列(21)。 根据优选实施例,保持装置包括布置成容纳物体(1)的膜(55),其中膜将物体(1)和匹配传播介质(53)彼此分离。 此外,描述使用成像装置(100)对物体(1)的光声成像的成像方法。

    AN APPARATUS AND METHOD FOR DETECTING SURFACE DEFECTS ON A WORKPIECE SUCH AS A ROLLED/DRAWN METAL BAR
    267.
    发明申请
    AN APPARATUS AND METHOD FOR DETECTING SURFACE DEFECTS ON A WORKPIECE SUCH AS A ROLLED/DRAWN METAL BAR 审中-公开
    用于检测工件上的表面缺陷的设备和方法,如轧制/拉制金属棒

    公开(公告)号:WO2007016544A2

    公开(公告)日:2007-02-08

    申请号:PCT/US2006/029884

    申请日:2006-07-31

    CPC classification number: G01N21/952 G01N2201/0826 G01N2201/084 H04N7/18

    Abstract: The present invention is directed to solving the problems associated with the detection of surface defects on metal bars as well as the problems associated with applying metal flat inspection systems to metal bars for non-destructive surface defects detection. A specially designed imaging system, which is comprised of a computing unit, line lights and high data rate line scan cameras, is developed for the aforementioned purpose. The target application is the metal bars (1) that have a circumference/cross-section-area ratio equal to or smaller than 4.25 when the cross section area is unity for the given shape, (2) whose cross-sections are round, oval, or in the shape of a polygon, and (3) are manufactured by mechanically cross-section reduction processes. The said metal can be steel, stainless steel, aluminum, copper, bronze, titanium, nickel, and so forth, and/or their alloys. The said metal bars can be at the temperature when they are being manufactured. A removable cassette includes various mirrors. A protection tube isolates the moving metal bar from the line light assembly and image acquisition camera. assembly and image acquisition camera. A contaminant reduction mechanism applies a vacuum to remove airborne contaminants.

    Abstract translation: 本发明旨在解决与检测金属条上的表面缺陷相关的问题以及与将金属平坦检查系统应用于金属棒以进行非破坏性表面缺陷检测相关的问题。 为了上述目的而开发了一种专门设计的成像系统,其由计算单元,线灯和高数据速率线扫描相机组成。 目标应用是当横截面面积对于给定形状为单位时具有等于或小于4.25的圆周/横截面积比的金属棒(1),(2)其横截面为圆形,椭圆形 ,或多边形的形状,(3)通过机械横截面缩小工艺制造。 所述金属可以是钢,不锈钢,铝,铜,青铜,钛,镍等,和/或它们的合金。 所述金属棒在制造时可处于该温度。 一个可移动的卡带包括各种镜子。 保护管将移动的金属条与线照明组件和图像采集相机隔离开来。 组装和图像采集相机。 污染物减少机制应用真空去除空气污染物。

    INSTRUMENTATION AND METHOD ADAPTED FOR OPTICAL MEASUREMENT OF AN AMPLIFIED LUMINESCENT PROXIMITY HOMOGENEOUS ASSAY
    268.
    发明申请
    INSTRUMENTATION AND METHOD ADAPTED FOR OPTICAL MEASUREMENT OF AN AMPLIFIED LUMINESCENT PROXIMITY HOMOGENEOUS ASSAY 审中-公开
    适用于放大的LUMINESCENT近似均质测定的光学测量的仪器和方法

    公开(公告)号:WO2006027406A1

    公开(公告)日:2006-03-16

    申请号:PCT/FI2004/000525

    申请日:2004-09-10

    Inventor: KIVELÄ, Petri

    Abstract: The present invention relates generally to the field of biochemical laboratory instrumentation for different applications of measuring properties of samples on e.g. microtitration plates and corresponding sample supports. The object of the invention is achieved by providing an optical measurement instrumentation wherein a sample (281-285) is activated (212AS, 218AS) and the emission is detected (291, 292), wherein between the activation and detection phases of measuring the sample, a shift is made in the relative position between the sample and means (218) directing the activation radiation to the sample as well as in the relative position between the sample and the means (293) receiving the emission radiation from the sample. This can be implemented e.g. by moving (299) the sample assay plate and/or a measuring head between the activation and emission phases of a sample. The invention allows a simultaneous activation of a first sample and detecting emission from a second sample thus enhancing efficiency of the measurement.

    Abstract translation: 本发明一般涉及生物化学实验室仪器领域,用于不同应用样品的测量性质。 微量滴定板和相应的样品支架。 本发明的目的是通过提供一种光学测量仪器实现的,其中样品(281-285)被激活(212AS,218AS)并且检测到发射(291,292),其中在测量样品的激活和检测阶段之间 在样品和将激活辐射指向样品的装置(218)之间的相对位置以及样品和接收来自样品的发射辐射的装置(293)之间的相对位置进行位移。 这可以被实现。 通过在样品的活化和发射阶段之间移动(299)样品测定板和/或测量头。 本发明允许同时激活第一样品并检测来自第二样品的发射,从而提高测量的效率。

    MODIFICATION OF THE NORMALIZED DIFFERENCE METHOD FOR REAL-TIME OPTICAL TOMOGRAPHY
    269.
    发明申请
    MODIFICATION OF THE NORMALIZED DIFFERENCE METHOD FOR REAL-TIME OPTICAL TOMOGRAPHY 审中-公开
    用于实时光学测量的正则化差分方法的修改

    公开(公告)号:WO2003088133A1

    公开(公告)日:2003-10-23

    申请号:PCT/US2003/010524

    申请日:2003-04-07

    Abstract: Computation -saving techniques and stability-adding techniques provide for fast, accurate reconstructions of a time series of images involving large scale 3D problems, such as real-time image recovery in an optical tomography imaging system. A system equation for a target medium (116) such as a tissue is solved using a Normalized Difference Method (NDM) (250). Because of the inherent stability of the NDM solutions, a weight matrix (W) of the system equation can be provided for a given point in a time series (220), then reused without recalculation at subsequent points. Further saving are achieved by decomposing W using singular value decomposition or direst matrix decomposition, transforming it to reduce its dimensions, and/or scaling it to achieve a more stable numerical solution. Values of measured energy (112) emerging from the target medium are back-substituted into the system equation for the different points to obtain the target medium properties.

    Abstract translation: 计算保存技术和稳定性添​​加技术可以快速,准确地重建涉及大规模3D问题的时间序列图像,例如光学层析成像系统中的实时图像恢复。 使用归一化差分法(NDM)(250)解决诸如组织的目标介质(116)的系统方程式。 由于NDM解决方案的固有稳定性,可以为时间序列(220)中的给定点提供系统方程的权重矩阵(W),然后在后续点重新计算。 通过使用奇异值分解或直接矩阵分解来分解W来实现进一步节省,将其变换以减小其尺寸和/或缩放以实现更稳定的数值解。 从目标介质出现的测量能量(112)的值被替代为不同点的系统方程,以获得目标介质特性。

    METHOD FOR DIRECT MEASUREMENT OF POLYCARBONATE COMPOSITIONS BY FLUORESCENCE
    270.
    发明申请
    METHOD FOR DIRECT MEASUREMENT OF POLYCARBONATE COMPOSITIONS BY FLUORESCENCE 审中-公开
    通过荧光直接测量聚碳酸酯组合物的方法

    公开(公告)号:WO01022065A1

    公开(公告)日:2001-03-29

    申请号:PCT/US2000/025751

    申请日:2000-09-20

    Abstract: The present invention provides a method for directly determining the concentration of a target species, such as Fries product, in a composition comprising aromatic carbonate chain units. In an exemplary embodiment, the method includes the steps of irradiating a portion of the composition with electromagnetic radiation at an excitation wavelength sufficient to cause the target species to emit a fluorescence spectrum; detecting at least a portion of the fluorescence spectrum; and determining the concentration of the target species form the fluorescence spectrum. In addition to detecting Fries product in formed polycarbonate materials, the method can also be utilized to directly determine the concentration of a target species in parallel polycarbonate reactor systems.

    Abstract translation: 本发明提供了一种在包含芳族碳酸酯链单元的组合物中直接测定目标物种如Fries产品的浓度的方法。 在示例性实施例中,该方法包括以足以引起目标物质发射荧光光谱的激发波长的电磁辐射照射组合物的一部分的步骤; 检测至少一部分荧光光谱; 并确定靶物种的浓度形成荧光光谱。 除了在形成的聚碳酸酯材料中检测Fries产品之外,该方法还可以用于直接确定平行聚碳酸酯反应器系统中的靶物种的浓度。

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