Abstract:
The present invention relates to a device and a method for simultaneously measuring the molecular binding characteristics of low molecular bio substances and the refractive index of a buffer solution using an ellipsometry under an immersed microchannel environment and, more specifically, to a device and a method for simultaneously measuring the refractive index of a buffer solution and the dynamic binding characteristics of bio substances at high sensitiveness by introducing polarized incident beams to an adsorption layer formed of the bio substances on substrate substances for semiconductors using a prism structure and a microchannel under p-wave non-reflective conditions. The device comprises: a microchannel structure; a sample injection part for forming the adsorption layer of a sample on a substrate by injecting the buffer solution containing the sample of the bio substances to the microchannel; a polarized beam generation part for radiating the incident beams polarized through the incident surface of a prism to the adsorption layer at an incident angle satisfying the p-wave non-reflective conditions; and a polarized beam detection part for detecting the polarized beam variation of reflected beams after the reflected beams of the adsorption layer are introduced through the reflection surface of the prism. The microchannel structure comprises: the substrate composed of a support, and semiconductors or dielectric substances formed on the support; a cover part formed as the prism structure and installed in the support; and the microchannel formed on one among the upper part of the support and the bottom of the cover part.
Abstract:
A measurement apparatus includes a light source assembly configured to emit light to a sample, a measuring device configured to measure reflected light, and a stage on which the sample is provided, where the light source assembly includes a first plate, a plurality of light sources connected to the first plate and a blocking panel comprising a hole, and one of the plurality of light sources is aligned with the hole in a first direction.
Abstract:
A light intensity measurement system includes a light source unit configured to emit coherent light to aqueous humor of a subject eye, a polarization control unit that is arranged between the light source unit and the subject eye, and configured to control a polarization state of the coherent light, and a measurement unit configured to measure light intensity of scattered light in the aqueous humor of the coherent light. With this configuration, a light intensity measurement system that can non-invasively measure the concentration of substances contained in aqueous humor of a subject eye is provided.
Abstract:
Devices, systems and methods are described that enable formation of microscopic images with enhanced resolution and high specificity, which among other features and benefits can lead to increased diagnostic accuracy of skin diseases, and decrease the time needed for rendering a diagnosis and the time required for training medical personnel. One optical imaging device includes a condenser, a polarizing beam splitter, an objective lens, and an immersion medium that are arranged in a configuration that allows cross polarization imaging of a sample. The described devices can be implemented using inexpensive optoelectrical components, as well as using existing optical and processing components of commonly used mobile devices, which makes it possible to construct the microscopy devices and systems at low cost for use in a wide range of clinical settings.