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21.发明公开상황버섯 균사체와 산삼 배양근 혼합 추출물을 유효성분으로 함유하는 폐암 예방 또는 치료용 약학적 조성물 有权用于预防或治疗含有PHELLINUS LINTEUS MYCELIUM和培养的PANAX GINSENG CAMEYER作为活性成分的混合提取物的癌症的药物组合物
公开(公告)号：KR1020110119606A
公开(公告)日：2011-11-02
申请号：KR1020110105871
申请日：2011-10-17
Applicant: 주식회사한국신약
IPC: A61K36/07 , A61K36/258 , A23L1/30 , A23L1/28
Abstract: PURPOSE: A neutraceutical composition containing mixture extract of Phellinus linteus mycelium and cultured wild ginseng roots for anti-cancer is provided. CONSTITUTION: A pharmaceutical composition for anti-cancer contains mixture extract of Phellinus linteus mycelium powder and cultured wild ginseng roots mixed in a weight ratio of 1:1-5:1. The mixture extract is isolated using water, organic solvent or mixture solvent thereof. The organic solvent is C1-C4 alcohol, ethyl acetate, methylene chloride, or chloroform. The ethanol is 40-60% ethanol. A pharmaceutical composition for preventing or treating cancer contains the mixture extract as an active ingredient.
Abstract translation: 目的：提供含有桑黄菌丝体的混合提取物和培养的人参根用于抗癌的药物组合物。 构成：用于抗癌的药物组合物含有以1:1-5:1的重量比混合的桑黄菌丝体和培养的人参根的混合提取物。 使用水，有机溶剂或其混合溶剂分离混合物萃取物。 有机溶剂是C1-C4醇，乙酸乙酯，二氯甲烷或氯仿。 乙醇为40-60％乙醇。 用于预防或治疗癌症的药物组合物含有混合物提取物作为活性成分。
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公开(公告)号：KR101062172B1
公开(公告)日：2011-09-05
申请号：KR1020080137698
申请日：2008-12-31
Applicant: 주식회사한국신약
CPC classification number: A23L33/105 , A23L5/00 , A23L31/00 , A23L33/10
Abstract: 본 발명은, 버섯 발효 인삼 분말을 함유하는 항암용 건강식품에 관한 것으로, 인삼을 건조하는 단계; 상기 인삼을 멸균하는 단계; 상기 인삼에 버섯종균을 접종 및 발효시켜 발효물을 만드는 단계; 상기 발효물을 분쇄하는 단계를 포함한다. 이로써, 발효인삼은 종래의 인삼과 버섯종균을 발효시킴으로써 암세포의 신생을 억제하고, 암세포의 자살을 유도하며, 전이를 억제하는 등의 항암작용과 혈당을 낮추는 작용에 더 효과적이다.
버섯종균, 인삼, 발효인삼, 사포닌, 항암작용-
公开(公告)号：KR101033671B1
公开(公告)日：2011-05-12
申请号：KR1020080137733
申请日：2008-12-31
Applicant: 주식회사한국신약
Abstract: 본 발명은 상황버섯 추출물과 동충하초 추출물을 포함하는 암 예방 또는 개선용 건강식품에 관한 것으로서, 상황버섯과 동충하초 균사체가 1:5 내지 5:1의 중량비율로 혼합된 혼합물의 에탄올 추출물을 포함한다. 본 발명에 따른 상황버섯과 동충하초 추출물이 포함된 건강식품을 섭취함으로서, 암세포 자체의 억제와 번식속도를 억제하는 효과를 나타내 면역증강 및 항암효과가 있다. 따라서, 기존의 항암제와 병행할 때 이상적인 치료효과를 볼 수 있다.
상황버섯, 동충하초, 항암효과, LLC세포, 건강식품-
24.发明公开
公开(公告)号：KR1020110043195A
公开(公告)日：2011-04-27
申请号：KR1020090100207
申请日：2009-10-21
Applicant: 주식회사한국신약
IPC: A61K31/192 , A61P17/18 , A61K31/216 , A61K8/36
Abstract: PURPOSE: A composition containing caffeoyl quinic acid derivatives and pharmaceutically acceptable salt thereof is provided to effectively suppress elastase activity of human neutrophil and to ensure anti-wrinkling. CONSTITUTION: A composition contains caffeoyl quinic acid derivatives and pharmaceutically acceptable salt thereof as an active ingredient. The composition is derived from one selected from the group consisting of (1S,3R,4R,5R)-3,4-bis((E)-3-(3,4-dihydroxyphenyl)acryloyloxy)-1,5 dihydroxycyclohexane carboxylic acid, (1S,3R,4R,5R)-methyl-3,4-bis((E)-3-(3,4-dihydroxyphenyl)acryloyloxy)-1,5-dihydroxycyclohexanecarboxylate, (1R,3R,4S,5R)-methyl-4,5-bis((E)-3-(3,4-dihydroxyphenyl)acryloyloxy)-1,5-dihydroxycyclohexanecarboxylate, (1S,3R,4S,5R)-3,5-bis((E)-3-(3,4-dihydroxyphenyl)acryloyloxy)-1,4-dihydroxycyclohexanecarboxylic acid, and (1S,3R,4S,5R)-methyl-3,5-bis((E)-3-(3,4-dihydroxyphenyl)acryloyloxy)-1,4-dihydroxycyclohexanecarboxylate.
Abstract translation: 目的：提供含有咖啡酰奎尼酸衍生物及其药学上可接受的盐的组合物，以有效抑制人嗜中性粒细胞的弹性蛋白酶活性并确保抗皱纹。 构成：组合物含有咖啡酰奎尼酸衍生物及其药学上可接受的盐作为活性成分。 该组合物衍生自选自（1S，3R，4R，5R）-3,4-双（（E）-3-（3,4-二羟基苯基）丙烯酰氧基）-1,5-二羟基环己烷羧酸 ，（1S，3R，4R，5R） - 甲基-3,4-二（（E）-3-（3,4-二羟基苯基）丙烯酰氧基）-1,5-二羟基环己烷羧酸酯，（1R，3R，4S，5R） （（E）-3-（3,4-二羟基苯基）丙烯酰氧基）-1,5-二羟基环己烷羧酸酯，（1S，3R，4S，5R）-3,5-双（（E） -3-（3,4-二羟基苯基）丙烯酰氧基）-1,4-二羟基环己烷羧酸和（1S，3R，4S，5R） - 甲基-3,5-双（（E） 二羟基苯基）丙烯酰氧基）-1,4- dihydroxycyclohexanecarboxylate。
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公开(公告)号：KR1020110043194A
公开(公告)日：2011-04-27
申请号：KR1020090100206
申请日：2009-10-21
Applicant: 주식회사한국신약
IPC: A61K36/185 , A61P17/18 , A61K8/97 , A23L1/30
Abstract: PURPOSE: A composition containing Ilex paraguayensis extract or fraction thereof is provided to effectively suppress elastase activity and to ensure anti-wrinkling effect. CONSTITUTION: A composition contains Ilex paraguayensis extract or fraction thereof as an active ingredient. The extract is isolated using water, organic solvent, or mixture thereof. A method for preparing a pharmaceutical composition containing Ilex paraguayensis extract and fraction for anti-wrinkling comprises: a step of extracting Ilex paraguayensis with water, organic solvent, or mixture solvent thereof; and a step of fractioning the extract with n-hexane and ethyl acetate.
Abstract translation: 目的：提供含有白藜芦醇提取物或其馏分的组合物以有效抑制弹性蛋白酶活性并确保抗起皱效果。 构成：组合物含有作为活性成分的白藜芦醇提取物或其分数。 使用水，有机溶剂或其混合物分离提取物。 一种制备含有白僵菌提取物和用于抗皱的部分的药物组合物的方法包括：用水，有机溶剂或其混合溶剂萃取白藜芦醇的步骤; 和用正己烷和乙酸乙酯分级提取物的步骤。
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Patent Agency Ranking26.发明公开
公开(公告)号：KR1020100112598A
公开(公告)日：2010-10-19
申请号：KR1020107016851
申请日：2007-12-07
Applicant: 주식회사한국신약
CPC classification number: A61K36/07
Abstract: PURPOSE: A composition for suppressing immunity containing Phellinus linteusau extract or composition for preventing and treating dermatitis are provided to suppress generation amount of antibody without side effects and toxicity. CONSTITUTION: A composition for suppressing immunity contains Phellinus linteusau extract as an active ingredient. The Phellinus linteusau includes Phellinuse Linteus, Phellinus Baumii or Phellinus Igniarius. The composition is administered by oral administration, intravenous administration or intraperitoneal injection. A composition for preventing and treating dermatitis contains Phellinus Igniarius extract as an active ingredient.
Abstract translation: 目的：提供用于抑制含有桑黄提取物或用于预防和治疗皮炎的组合物的免疫力的组合物，以抑制抗体的产生量而没有副作用和毒性。 构成：用于抑制免疫的组合物含有桑黄提取物作为活性成分。 桑黄素包括Phellinuse Linteus，Phellinus Baumii或Phellinus Igniarius。 组合物通过口服给药，静脉内给药或腹膜内注射给药。 用于预防和治疗皮炎的组合物含有作为活性成分的桑黄提取物。
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公开(公告)号：KR1020100112597A
公开(公告)日：2010-10-19
申请号：KR1020107016849
申请日：2007-12-07
Applicant: 주식회사한국신약
IPC: A61K36/068 , A61K36/066 , A61P17/00 , A61P37/00
CPC classification number: A61K36/068
Abstract: PURPOSE: A composition for suppressing immunity or preventing and treating dermatitis containing Cordyceps sinensis extract is provided to use as an inhibitor during organ transplantation without side effects. CONSTITUTION: A composition for suppressing immunity contains Cordyceps sinensis extract as an active ingredient. The composition is administered by oral administration, intravenous administration or intraperitoneal injection. The amount of administration is 550-2,200 mg/day. A composition for preventing and treating dermatitis contains Cordyceps sinensis extract as an active ingredient. The dermatitis includes atopy, allergy, decubitus, or smallpox.
Abstract translation: 目的：提供一种用于抑制免疫力或预防和治疗含有冬虫夏草提取物的皮炎的组合物，用作器官移植期间的抑制剂，无副作用。 构成：用于抑制免疫的组合物含有冬虫夏草提取物作为活性成分。 组合物通过口服给药，静脉内给药或腹膜内注射给药。 给药量为550-2200mg /天。 用于预防和治疗皮炎的组合物含有冬虫夏草提取物作为活性成分。 皮炎包括特应性，过敏，褥疮或天花。
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公开(公告)号：KR1020100079303A
公开(公告)日：2010-07-08
申请号：KR1020080137733
申请日：2008-12-31
Applicant: 주식회사한국신약
Abstract: PURPOSE: Anticancer health food including Phellinus linteus and Cordyceps militaris is provided to prevent cancer or treat cancer with pills by mixing mixed extract of Phellinus linteus and Cordyceps militaris with excipient. CONSTITUTION: Health food for prevention and improving cancer contains extract of Phellinus linteus and Cordyceps militaris with a weight ratio of 1:5 ~ 5:1 as a beneficial component. The extract contains aqueous and ethanolic extract of Phellinus linteus and Cordyceps militaris mycelium mixture as the beneficial component. An ethanol water solution contains the ethanol water solution extract of 40 ~ 60% as the beneficial component.
Abstract translation: 目的：通过将桑黄和冬虫夏草的混合提取物与赋形剂混合，提供包括桑黄和冬虫夏草在内的抗癌保健食品，用于预防癌症或用药丸治疗癌症。 构成：预防和改善癌症的保健食品含有以1:5〜5:1的重量比作为有益成分的桑黄和冬虫夏草提取物。 提取物含有桑黄和冬虫夏草菌丝体混合物的水溶液和乙醇提取物作为有益成分。 乙醇水溶液含有40〜60％的乙醇水溶液提取物作为有益成分。
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公开(公告)号：KR100766433B1
公开(公告)日：2007-10-11
申请号：KR1020050053080
申请日：2005-06-20
Applicant: 주식회사한국신약
IPC: A61K36/07
Abstract: 본 발명은 비늘버섯(
Pholiota squarrosa ) 추출물을 포함하는 항암 및 암전이 억제용 조성물에 관한 것으로서, 본 발명에 따른 비늘버섯 추출물은 암세포에 대한 독성이 강하고, 암세포에서 Bcl-2와 같은 세포사멸 억제 단백질의 발현에는 영향을 미치지 않는 반면, 카스파아제 Ⅲ과 같은 세포사멸 유도 단백질의 발현을 증가시키고, 매트릭스메탈로프로테아제(MMP) 중 MMP-2 및 MMP-9의 발현을 억제하므로, 항암 및 암전이 억제 효과가 우수한 의약품 및 건강식품으로 유용하게 사용될 수 있다.-
公开(公告)号：KR100596827B1
公开(公告)日：2006-07-03
申请号：KR1020030100576
申请日：2003-12-30
Applicant: 주식회사한국신약
IPC: A23L1/30
Abstract: 본 발명은 홍삼 및 펠리누스 속(
Phellinus sp. ) 균주의 균사체에서 추출한 다당류를 유효성분으로 함유하는 식품첨가물에 관한 것이다. 본 발명의 식품첨가물은 면역력 증강, 항암, 항스트레스 및 혈장 콜레스테롤 감소 작용 등에 관여하는 성분들을 함유하고 있어 다양한 질병에 대한 치료 및 예방의 건강식품에 사용될 수 있다.
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