公开(公告)号：WO2009099450A1

公开(公告)日：2009-08-13

申请号：PCT/US2008/058650

申请日：2008-03-28

Applicant: COLGATE-PALMOLIVE COMPANY ,  ROBINSON, Richard, Scott ,  SULLIVAN, Richard, J. ,  PRENCIPE, Michael ,  VAN RYCKE, Isabelle ,  LOVELL, Richard ,  KOHLI, Rajnish ,  LEITE, Sergio ,  SIMON, Eric, A. ,  SANTARPIA, Ralph, Peter, III ,  CUMMINS, Diane ,  MELLO, Sarita, V. ,  CHOPRA, Suman, K. ,  DEPIERRO, Karen ,  ZAIDEL, Lynette ,  CHRISTOPOULOU, Constantina ,  SUBRAMANYAM, Ravi ,  WU, Donghui ,  MORGAN, Andre, M. ,  WANG, Qin ,  TAMBS, Gary, Edward ,  BARNES, Virginia, Monsul

Inventor： ROBINSON, Richard, Scott ,  SULLIVAN, Richard, J. ,  PRENCIPE, Michael ,  VAN RYCKE, Isabelle ,  LOVELL, Richard ,  KOHLI, Rajnish ,  LEITE, Sergio ,  SIMON, Eric, A. ,  SANTARPIA, Ralph, Peter, III ,  CUMMINS, Diane ,  MELLO, Sarita, V. ,  CHOPRA, Suman, K. ,  DEPIERRO, Karen ,  ZAIDEL, Lynette ,  CHRISTOPOULOU, Constantina ,  SUBRAMANYAM, Ravi ,  WU, Donghui ,  MORGAN, Andre, M. ,  WANG, Qin ,  TAMBS, Gary, Edward ,  BARNES, Virginia, Monsul

IPC: A61K8/44 ,  A61Q11/00 ,  A61K31/198 ,  A61P1/02

CPC classification number: A61K8/44 ,  A61K31/198 ,  A61Q11/00

Abstract: The invention includes methods of cleaning an oral surface, maintaining oral health and/or increasing oral health. Such methods encompass contacting an oral surface with a primary oral care composition at least once daily, contacting the oral surface with a periodic oral care maintenance composition at least once monthly, wherein the periodic oral care maintenance composition comprises a basic amino acid, in free or salt form and optionally contacting the oral surface with a periodic oral care cleaning composition at least once monthly. The periodic oral care cleaning compositions suitable for use in the method comprise an abrasive system.

Abstract translation: 本发明包括清洁口腔表面，维持口腔健康和/或增加口腔健康的方法。 这样的方法包括每天至少一次使口腔表面与主要口腔护理组合物接触，使口腔表面与定期的口腔护理维持组合物每月至少一次接触，其中定期口腔护理维持组合物包含游离或 任选地使口腔表面与定期的口腔护理清洁组合物每月至少一次接触。 适用于该方法的定期口腔护理清洁组合物包括研磨系统。

公开(公告)号：WO2009100264A3

公开(公告)日：2009-11-05

申请号：PCT/US2009033290

申请日：2009-02-06

Applicant: COLGATE PALMOLIVE CO ,  KOHLI RAJNISH ,  ROBINSON RICHARD ,  SULLIVAN RICHARD ,  CUMMINS DIANE

Inventor： KOHLI RAJNISH ,  ROBINSON RICHARD ,  SULLIVAN RICHARD ,  CUMMINS DIANE

IPC: A61K8/44 ,  A61K8/20 ,  A61Q11/00

CPC classification number: A61Q11/00 ,  A61K8/21 ,  A61K8/44 ,  A61K31/09 ,  A61K31/198 ,  A61K33/16 ,  A61K2300/00

Abstract: This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form and a low dosage of fluoride and to methods of using such compositions.

Abstract translation: 本发明涉及包含游离或盐形式的有效量的碱性氨基酸和低剂量的氟化物的口腔护理组合物以及使用这种组合物的方法。

公开(公告)号：WO2009099454A1

公开(公告)日：2009-08-13

申请号：PCT/US2008/058704

申请日：2008-03-28

Applicant: COLGATE-PALMOLIVE COMPANY ,  PRENCIPE, Michael ,  SUBRAMANYAM, Ravi ,  MELLO, Sarita, V. ,  WU, Donghui ,  CHOPRA, Suman, K. ,  MORGAN, Andre, M. ,  CUMMINS, Diane ,  SULLIVAN, Richard, J. ,  SANTARPIA, Ralph, Peter III ,  ZAIDEL, Lynette ,  WANG, Qin ,  TAMBS, Gary, Edward ,  BARNES, Virginia, Monsul ,  KOHLI, Rajnish ,  ROBINSON, Richard, Scott ,  LEITE, Sergio ,  SIMON, Eric, A.

Inventor： PRENCIPE, Michael ,  SUBRAMANYAM, Ravi ,  MELLO, Sarita, V. ,  WU, Donghui ,  CHOPRA, Suman, K. ,  MORGAN, Andre, M. ,  CUMMINS, Diane ,  SULLIVAN, Richard, J. ,  SANTARPIA, Ralph, Peter III ,  ZAIDEL, Lynette ,  WANG, Qin ,  TAMBS, Gary, Edward ,  BARNES, Virginia, Monsul ,  KOHLI, Rajnish ,  ROBINSON, Richard, Scott ,  LEITE, Sergio ,  SIMON, Eric, A.

IPC: A61K8/44 ,  A61K8/34 ,  A61Q11/00 ,  A61K31/198 ,  A61P1/02 ,  A61K31/085

CPC classification number: A61K8/44 ,  A61K8/19 ,  A61K8/21 ,  A61K8/24 ,  A61K31/198 ,  A61Q11/00

Abstract: This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an antibacterial agent, and to methods of using and of making such compositions.

Abstract translation: 本发明涉及包含游离或盐形式的有效量的碱性氨基酸与抗菌剂的口腔护理组合物，以及使用和制备这些组合物的方法。

公开(公告)号：WO2009099453A1

公开(公告)日：2009-08-13

申请号：PCT/US2008/058696

申请日：2008-03-28

Applicant: COLGATE-PALMOLIVE COMPANY ,  KOHLI, Rajnish ,  ROBINSON, Richard, Scott ,  LEITE, Sergio ,  SIMON, Eric, A. ,  SULLIVAN, Richard, J. ,  SANTARPIA III, Ralph, Peter ,  PRENCIPE, Michael ,  SUBRAMANYAM, Ravi ,  MELLO, Sarita, V. ,  WU, Donghui ,  CHOPRA, Suman, K. ,  MORGAN, Andre, M. ,  CUMMINS, Diane ,  ZAIDEL, Lynette ,  WANG, Qin ,  TAMBS, Gary, Edward ,  BARNES, Virginia, Monsul

Inventor： KOHLI, Rajnish ,  ROBINSON, Richard, Scott ,  LEITE, Sergio ,  SIMON, Eric, A. ,  SULLIVAN, Richard, J. ,  SANTARPIA III, Ralph, Peter ,  PRENCIPE, Michael ,  SUBRAMANYAM, Ravi ,  MELLO, Sarita, V. ,  WU, Donghui ,  CHOPRA, Suman, K. ,  MORGAN, Andre, M. ,  CUMMINS, Diane ,  ZAIDEL, Lynette ,  WANG, Qin ,  TAMBS, Gary, Edward ,  BARNES, Virginia, Monsul

IPC: A61K8/44 ,  A61K8/21 ,  A61K8/24 ,  A61K8/19 ,  A61Q11/00 ,  A61K31/198 ,  A61P1/02

CPC classification number: A61K8/44 ,  A61K8/19 ,  A61K8/21 ,  A61K8/24 ,  A61K31/198 ,  A61Q11/00

Abstract: This invention relates to oral care compositions comprising an effective amount of a salt of a basic amino acid, the salt having a pH in an unbuffered solution of less than about 7.5: an effective amount of a soluble fluoride salt: and a particulate material which has a pH in an unbuffered solution of less than about 7.5; and to methods of using and of making such compositions.

Abstract translation: 本发明涉及口腔护理组合物，其包含有效量的碱性氨基酸盐，所述盐的无缓冲溶液中的pH小于约7.5：有效量的可溶性氟化物盐和具有 无缓冲溶液中的pH小于约7.5; 以及使用和制备这种组合物的方法。

公开(公告)号：WO2009045952A1

公开(公告)日：2009-04-09

申请号：PCT/US2008/078101

申请日：2008-09-29

Applicant: COLGATE-PALMOLIVE COMPANY ,  CUMMINS, Diane

Inventor： CUMMINS, Diane

IPC: A61K36/15 ,  A61K36/35 ,  A61K36/67 ,  A61K36/18 ,  A61K36/45 ,  A61K36/77 ,  A61K36/23 ,  A61K36/53 ,  A61K36/82 ,  A61K36/28 ,  A61K36/537 ,  A61K36/9066 ,  A61K36/324 ,  A61K36/539 ,  A61P31/02

CPC classification number: A61K36/15 ,  A61K36/18 ,  A61K36/23 ,  A61K36/28 ,  A61K36/324 ,  A61K36/35 ,  A61K36/45 ,  A61K36/53 ,  A61K36/537 ,  A61K36/539 ,  A61K36/67 ,  A61K36/77 ,  A61K36/82 ,  A61K36/9066

Abstract: The disclosure provides oral compositions having at least two botanical active ingredients derived from plants. The oral composition also includes an orally acceptable vehicle to deliver an effective amount of the at least two active ingredients in vivo. The botanical active ingredients provide particularly efficacious antimicrobial (antibacterial, antiviral, and/or antifungal), antioxidant, anti-inflammatory, anti-ageing, and or healing properties to the oral compositions.

Abstract translation: 本公开提供了具有至少两种衍生自植物的植物活性成分的口服组合物。 口服组合物还包括口服可接受的载体以在体内递送有效量的至少两种活性成分。 植物活性成分为口服组合物提供特别有效的抗微生物（抗菌，抗病毒和/或抗真菌），抗氧化，抗炎，抗衰老和/或愈合。