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    Device for mixing a medical paste
    24.
    发明授权
    Device for mixing a medical paste 有权

    公开(公告)号：US12059139B2

    公开(公告)日：2024-08-13

    申请号：US17056595

    申请日：2019-06-26

    Applicant: Ferrosan Medical Devices A/S

    Inventor： Kristian Larsen ,  Peter Lund Hammershøj

    IPC: A61B17/00 ,  A61J1/20

    CPC classification number: A61B17/00491 ,  A61J1/2037 ,  A61J1/2055 ,  A61J1/2062 ,  A61J1/2089 ,  A61J1/2096 ,  A61B2017/00495

    Abstract: The invention regards a device for reconstituting a bioactive agent and forming a paste, the device comprising:—a container (2) containing the bioactive agent,—a first syringe (4) containing a liquid,—a second syringe (5) containing a paste forming material,—a connector element (6) configured for establishing sequential fluid connections between 1) the first syringe and the container, 2) the container and the second syringe, and 3) the first and second syringes, such that the liquid can be transferred from the first syringe to the container to reconstitute the bioactive agent, whereupon the reconstituted bioactive agent can be transferred from the container into the second syringe to form a paste, and the paste can be transferred to the first syringe.

    Syringe for mixing two components and for retaining a vacuum in a storage condition
    26.
    发明授权
    Syringe for mixing two components and for retaining a vacuum in a storage condition 有权

    公开(公告)号：US10918796B2

    公开(公告)日：2021-02-16

    申请号：US15580181

    申请日：2016-06-30

    Applicant: Ferrosan Medical Devices A/S

    Inventor： Kristian Larsen ,  Lise Sjørup Elle ,  Thomas Ingemann Jensen

    IPC: A61M5/20 ,  A61M5/24 ,  A61M5/315 ,  A61M5/28 ,  A61M5/168 ,  A61M3/00

    Abstract: A syringe for mixing two substances which have been retained separately inside the syringe is described, for instance in a storage condition. The syringe is used for 1) retaining a dry composition in a vacuum, and 2) mixing the dry composition with an aqueous medium to form a flowable substance. One embodiment, a syringe for retaining and mixing first and second substances comprises a barrel comprising a sealable and/or closable distal outlet and a vacuum chamber for holding a first substance, a plunger incorporating a reservoir chamber for holding a second substance and configured to be axially displaced through a proximal end of the barrel, a membrane separating the vacuum chamber and the reservoir chamber, and a pointed member, such as one or more needles, for penetrating the membrane, wherein the syringe is configured such that the membrane and the pointed member are axially slidable in relation to each other.

    Syringe for retaining and mixing first and second substances
    27.
    发明授权
    Syringe for retaining and mixing first and second substances 有权

    公开(公告)号：US10653837B2

    公开(公告)日：2020-05-19

    申请号：US15534801

    申请日：2015-12-21

    Applicant: Ferrosan Medical Devices A/S

    Inventor： Kristian Larsen

    IPC: A61M5/19 ,  A61M5/24 ,  A61M5/315 ,  A61B17/00 ,  A61M5/31

    Abstract: The present disclosure relates to a syringe for retaining and/or mixing two substances which have been retained separately inside the syringe. In particular the present disclosure relates to a syringe for 1) retaining a dry composition in a vacuum, and 2) mixing the dry composition with an aqueous medium to form a flowable substance. One embodiment relates to a syringe for mixing first and second substances comprising a barrel comprising a vacuum chamber for holding a first substance, a plunger incorporating a reservoir chamber for holding a second substance and configured to be axially displaced in the vacuum chamber, and a valve for controlling and/or establishing a fluid connection between the vacuum chamber and the reservoir chamber.

    Dry Composition Comprising An Extrusion Enhancer
    28.
    发明申请
    Dry Composition Comprising An Extrusion Enhancer 审中-公开

    公开(公告)号：US20190015546A1

    公开(公告)日：2019-01-17

    申请号：US16129334

    申请日：2018-09-12

    Applicant: Ferrosan Medical Devices A/S

    Inventor： Kristian Larsen

    IPC: A61L26/00 ,  A61L24/10 ,  A61L24/00

    Abstract: Disclosed is a dry composition comprising one or more polyols, which upon addition of an aqueous medium forms a substantially homogenous paste suitable for use in haemostasis procedures. The paste reconstitutes spontaneously upon addition of the liquid; hence no mechanical mixing is required for said paste to form. The composition may further comprise an extrusion enhancer, such as albumin. Also disclosed are methods of preparing said dry composition, a paste obtained from said dry composition and uses of said dry composition or paste for medical and surgical purposes.

    Syringe for Retaining and Mixing First and Second Substances
    29.
    发明申请
    Syringe for Retaining and Mixing First and Second Substances 审中-公开

    公开(公告)号：US20180264194A1

    公开(公告)日：2018-09-20

    申请号：US15534801

    申请日：2015-12-21

    Applicant: Ferrosan Medical Devices A/S

    Inventor： Kristian Larsen

    IPC: A61M5/19 ,  A61M5/24 ,  A61M5/315

    CPC classification number: A61M5/19 ,  A61B2017/00495 ,  A61M5/2448 ,  A61M5/31501 ,  A61M5/31511 ,  A61M5/31596 ,  A61M2005/3128

    Abstract: The present disclosure relates to a syringe for retaining and/or mixing two substances which have been retained separately inside the syringe. In particular the present disclosure relates to a syringe for 1) retaining a dry composition in a vacuum, and 2) mixing the dry composition with an aqueous medium to form a flowable substance. One embodiment relates to a syringe for mixing first and second substances comprising a barrel comprising a vacuum chamber for holding a first substance, a plunger incorporating a reservoir chamber for holding a second substance and configured to be axially displaced in the vacuum chamber, and a valve for controlling and/or establishing a fluid connection between the vacuum chamber and the reservoir chamber.

    Device for promotion of hemostasis and/or wound healing
    30.
    发明授权
    Device for promotion of hemostasis and/or wound healing 有权
    促进止血和/或伤口愈合的装置

    公开(公告)号：US09533069B2

    公开(公告)日：2017-01-03

    申请号：US14136578

    申请日：2013-12-20

    Applicant: Ferrosan Medical Devices A/S

    Inventor： Kristian Larsen ,  Mads Sabra

    IPC: A61F13/00 ,  A61L24/00 ,  A61L26/00 ,  A61L24/10

    CPC classification number: A61L24/0036 ,  A61L24/0015 ,  A61L24/102 ,  A61L24/104 ,  A61L26/0066 ,  A61L26/0085 ,  A61L2300/254 ,  A61L2300/418

    Abstract: Disclosed is a matrix material comprising a pharmaceutical composition such as a matrix material with a pharmaceutical composition printed on the surface. In one embodiment the pharmaceutical composition comprises thrombin. Further disclosed is a method for making the matrix material with a pharmaceutical composition printed on the surface and use of said matrix material for promotion of hemostasis and/or wound healing. Also disclosed is a kit-of-parts comprising a matrix with a pharmaceutical composition and a container with a peelable lid.

    Abstract translation: 公开了一种基质材料，其包含药物组合物，例如在表面上印刷有药物组合物的基质材料。 在一个实施方案中，药物组合物包含凝血酶。 进一步公开的是制备具有印刷在表面上的药物组合物的基质材料并使用所述基质材料促进止血和/或伤口愈合的方法。 还公开了一种试剂盒，其包含具有药物组合物的基质和具有可剥离盖的容器。

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