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公开(公告)号：JP5654606B2
公开(公告)日：2015-01-14
申请号：JP2012533498
申请日：2010-09-13
Applicant: フェロサン メディカル デバイセズ アー/エスFerrosan Medical Devices A/S , フェロサン メディカル デバイセズ アー/エスFerrosan Medical Devices A/S
Inventor： フレミング ライススィー イェンスン , フレミング ライススィー イェンスン , ベッティーナ メツラー , ベッティーナ メツラー , マルティン ブエ ベルテルセン , マルティン ブエ ベルテルセン , ラスムス コーストロプ トーアコウ , ラスムス コーストロプ トーアコウ
CPC classification number: A61M25/005 , A61M35/003 , A61M2205/0216 , Y10T29/49826 , Y10T83/0596
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公开(公告)号：JP2013507994A
公开(公告)日：2013-03-07
申请号：JP2012533498
申请日：2010-09-13
Inventor： フレミング ライススィー イェンスン , ベッティーナ メツラー , マルティン ブエ ベルテルセン , ラスムス コーストロプ トーアコウ
CPC classification number: A61M25/005 , A61M35/003 , A61M2205/0216 , Y10T29/49826 , Y10T83/0596
Abstract: 可鍛性チップを備える、薬剤を標的部位に塗布するためのアプリケータデバイスであって、可鍛性チップは、看護包帯剪刀または同様の種類の剪刀で、ある長さに切断することができ、看護包帯剪刀または同様の種類の剪刀で、ある長さに切断することができる変形可能な管を備える、アプリケータデバイス。 可鍛性チップは、流体が通過するように構成され、可鍛性部材を含む。 可鍛性部材は、ある構成に曲げられた後、チップの形状を維持する程度の強度があるが、看護包帯剪刀または同等物で容易に切断される程度の軟質で弱い軟質金属でできている。 手術中または手術前に薬剤を標的部位に塗布するために好適である、アプリケータデバイスを準備するための方法は、アプリケータデバイスに変形可能なチップを提供することと、該チップを所望の形状に変形することと、看護包帯剪刀または同様の種類の剪刀で、該変形可能なチップを所望の長さに切断することとを含む。
【選択図】図６-
公开(公告)号：WO2020002438A1
公开(公告)日：2020-01-02
申请号：PCT/EP2019/067018
申请日：2019-06-26
Applicant: FERROSAN MEDICAL DEVICES A/S
Inventor： LARSEN, Kristian , HAMMERSHØJ, Peter, Lund
Abstract: The invention regards a device for reconstituting a bioactive agent and forming a flowable paste, the device comprising: - a base configured for receiving: - a first container containing a liquid, and - a second container containing the bioactive agent, - a syringe containing a paste forming material, the syringe being attachable to the base, wherein the base has a first conduit for fluidly connecting the first container with the second container and a second conduit for fluidly connecting the second container with the syringe, and wherein the first container is configured to be pressurizable such that when the first and second containers are received at the base, the liquid is forced through the first conduit into the second container, thereby reconstituting the bioactive agent, and the reconstituted bioactive agent is forced through the second conduit into the syringe, such that a paste is formed.
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公开(公告)号：WO2016058612A1
公开(公告)日：2016-04-21
申请号：PCT/DK2015/050311
申请日：2015-10-13
Applicant: FERROSAN MEDICAL DEVICES A/S
Inventor： LARSEN, Kristian , JENSEN, Flemming Reissig , MORTENSEN, Michael Wrang
IPC: A61L26/00
CPC classification number: A61L26/0038 , A61L26/0085
Abstract: The present disclosure relates to a dry composition which reconstitutes without mechanical mixing to form a flowable paste having a soft and light consistency suitable for use in haemostasis and wound healing procedures upon addition of an aqueous medium. The disclosure further relates to methods of preparing the dry composition, methods for reconstituting the dry composition and medical use of the composition.
Abstract translation: 本公开涉及一种干组合物，其在没有机械混合的情况下重组，以形成具有适于在加入水性介质的止血和伤口愈合过程中的柔软和轻度稠度的可流动糊剂。 本公开还涉及制备干组合物的方法，用于重构干组合物的方法和组合物的医疗用途。
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公开(公告)号：WO2015086028A1
公开(公告)日：2015-06-18
申请号：PCT/DK2014/050421
申请日：2014-12-10
Applicant: FERROSAN MEDICAL DEVICES A/S
Inventor： LARSEN, Kristian
IPC: A61L26/00
CPC classification number: A61L26/0066 , A61L24/0036 , A61L24/104 , A61L26/0009 , A61L26/0019 , A61L26/0038 , A61L26/0047 , A61L26/0052 , A61L26/0085 , A61L2300/254 , A61L2300/418 , A61L2400/04 , A61L2430/34
Abstract: Disclosed is a dry composition comprising one or more polyols, which upon addition of an aqueous medium forms a substantially homogenous paste suitable for use in haemostasis procedures. The paste reconstitutes spontaneously upon addition of the liquid;hence no mechanical mixing is required for said paste to form. The composition may further comprise an extrusion enhancer, such as albumin. Also disclosed are methods of preparing said dry composition, a paste obtained from said dry composition and uses of said dry composition or paste for medical and surgical purposes.
Abstract translation: 公开了一种干组合物，其包含一种或多种多元醇，其在加入水性介质时形成适合用于止血程序的基本均匀的糊剂。 糊剂在加入液体时自发地重新组装，因此不需要机械混合来形成所述糊料。 组合物还可以包含挤出增强剂，例如白蛋白。 还公开了制备所述干组合物的方法，由所述干组合物获得的糊剂以及所述干组合物或糊剂用于医疗和外科用途的用途。
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Patent Agency Ranking
公开(公告)号：WO2023285589A1
公开(公告)日：2023-01-19
申请号：PCT/EP2022/069720
申请日：2022-07-14
Applicant: FERROSAN MEDICAL DEVICES A/S
Inventor： HAMMERSHØJ, Peter Lund , IGWEBUIKE, Henning Uzoma , DEMANT, Lisbeth Nøhr , BRÜEL, Christian , ENGMARK, Mikael , BHATIA, Vikram Kjøller , AXELSSON, Lars Tamstrup , BATCHELOR, Simon
Abstract: The present disclosure relates to a laparoscopic applicator for dispensing a substance, e.g. a substance comprising a haemostatic agent, at a selected site by means of a surgical robotic arm, the laparoscopic applicator comprising a delivery tube; and an applicator tip connected to a distal end of the delivery tube, wherein the applicator tip is configured for being controllable operated by the robotic arm by a grip section in axial extension of the delivery tube, the grip section having a perimeter transverse to the axis comprising an apex shaped section, such that the grip section is configured forbeing clamped and spatially manipulated by the robotic arm.
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公开(公告)号：WO2022152824A1
公开(公告)日：2022-07-21
申请号：PCT/EP2022/050707
申请日：2022-01-14
Applicant: FERROSAN MEDICAL DEVICES A/S
Inventor： HAMMERSHØJ, Peter Lund , IGWEBUIKE, Henning Uzoma , DEMANT, Lisbeth Nøhr , BRÜEL, Christian , ENGMARK, Mikael , BHATIA, Vikram Kjøller , AXELSSON, Lars Tamstrup
Abstract: The present disclosure relates to a laparoscopic applicator for dispensing a substance, e.g. a substance comprising a haemostatic agent, at a selected site by means of a surgical robotic arm, the laparoscopic applicator comprising a delivery tube configured for holding the substance under a pressure; and an applicator tip connected to a distal 5end of the delivery tube, wherein the applicator tip is configured for being controllable operated by the robotic arm by being spatially manipulated by the robotic arm, and controllably releasing the substance from the delivery tube by the robotic arm.
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公开(公告)号：WO2022112543A1
公开(公告)日：2022-06-02
申请号：PCT/EP2021/083281
申请日：2021-11-29
Applicant: FERROSAN MEDICAL DEVICES A/S
IPC: A61J1/20
Abstract: The invention regards a vial adapter, comprising two chamber parts in axial extension of each other, wherein the first chamber part is configured for slidably receiving at least a part of the vial crown, and the second chamber part is configured for slidably receiving at least a part of the vial body, wherein the first chamber part and/or the second chamber part comprises one or more ribs extending radially inwardly of the chamber wall.
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公开(公告)号：WO2019215274A1
公开(公告)日：2019-11-14
申请号：PCT/EP2019/061903
申请日：2019-05-09
Applicant: FERROSAN MEDICAL DEVICES A/S , ETHICON INC.
Inventor： HAMMERSHØJ, Peter, Lund , LARSEN, Kristian , JOHNS, Douglas, B. , SMITH, Nicole , CARDINALE, Michael , FERRARA, Gabriella , ZHANG, Guanghui
Abstract: The present disclosure relates to a method for preparing a haemostatic composition comprising thrombin, the method comprising the step of reconstituting a dry thrombin directly in a paste, such as a paste comprising a biocompatible polymer. The haemostatic composition comprising thrombin may be prepared from a dry thrombin composition and a paste in a single step operation and be used for treatment of a wound.
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公开(公告)号：WO2011113436A1
公开(公告)日：2011-09-22
申请号：PCT/DK2011/050082
申请日：2011-03-14
Applicant: FERROSAN MEDICAL DEVICES A/S , LARSEN, Kristian
Inventor： LARSEN, Kristian
CPC classification number: A61L15/44 , A61L15/325 , A61L15/425 , A61L24/0015 , A61L24/0036 , A61L24/104 , A61L2300/412 , A61L2300/418
Abstract: The present invention relates to a matrix material comprising a pharmaceutical composition such as a matrix material with a pharmaceutical composition applied by ultrasonic spray technology on the surface. In one embodiment the pharmaceutical composition comprises thromb in. The invention further describes a method for making the matrix material which has a pharmaceutical composition coated onto the surface of the matrix material using ultrasonic spray technology. In one specific embodiment the invention also relates to the use of said matrix material for promotion of hemostasis and/or wound healing. The invention also relates to a kit-of-parts comprising a matrix with a pharmaceutical composition and a container with a peelable lid.
Abstract translation: 本发明涉及一种基质材料，其包含药物组合物，例如具有通过超声波喷涂技术在表面上施用的药物组合物的基质材料。 在一个实施方案中，药物组合物包含血栓。本发明进一步描述了使用超声波喷涂技术制备基质材料的方法，该基质材料具有涂覆在基质材料的表面上的药物组合物。 在一个具体实施方案中，本发明还涉及所述基质材料用于促进止血和/或伤口愈合的用途。 本发明还涉及包含具有药物组合物的基质和具有可剥离盖的容器的成分试剂盒。
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