公开(公告)号：GB2126464A

公开(公告)日：1984-03-28

申请号：GB8320950

申请日：1983-08-03

Applicant: PENTON ELLIOTT ,  STONE DAVID GEORGE PETER

Inventor： PENTON ELLIOTT ,  STONE DAVID GEORGE PETER

IPC: A01G9/16 ,  A01G13/02 ,  E04H15/40 ,  E04B1/347

Abstract: A portable or lightweight enclosure has a flexible cover sheet (1) which is anchored to a base (2) or to the ground. A number of flexurally stressed or spring-loaded arched supports (6) are located within the cover sheet, the lower of the supports being free and braced against the inside of the cover sheet (1) by the stressing or loading of the supports so as to maintain the cover sheet in tension. The opposite longitudinal edges (5) of the sheet may be attached to respective longitudinal base members (3) which may be filled with ballast. The lower ends of the arched supports (6) may be interconnected by longitudinal elements (7) through which irrigation water may be supplied.

公开(公告)号：GB2458710A

公开(公告)日：2009-09-30

申请号：GB0809104

申请日：2008-05-20

Applicant: STONE DAVID JOHN

Inventor： STONE DAVID JOHN

IPC: F28D1/03 ,  F21V29/02

Abstract: The heat exchanger 1 has a pair of spaced circular inner and outer walls 4,5 joined by a series of spaced ribs 6 extending in an axial direction between the opposite ends 2, 3 to form a series of parallel passageways 7. Interconnecting ports (e.g. 14a, fig 3) are milled or formed between adjacent passageways (fig 3), or groups of adjacent passageways (fig 4), at opposite ends of the extrusion, such that in one embodiment the fluid flows in opposite directions in the adjacent passageways or groups of adjacent passageways. A pair of end caps 9,10 close the ends 2,3 and have a respective fluid inlet 11 and a fluid outlet 12. An alternative embodiment (fig 5) has helical passageways. The heat exchanger may be an extrusion, moulding or welded; may be transparent or partially/wholly coloured black to absorb heat; and can be cylindrical, curved or flat. The ribs may be inclined to form a triangular cross-section passage (fig 7). The heat exchanger may be a radiator, solar panel, fireproof wall or part of a food processing machine; or cool a horticultural or industrial light bulb, or a chimney.

公开(公告)号：GB0806576D0

公开(公告)日：2008-05-14

申请号：GB0806576

申请日：2008-04-11

Applicant: STONE DAVID J

公开(公告)号：GB9517740D0

公开(公告)日：1995-11-01

申请号：GB9517740

申请日：1995-08-31

Applicant: STONE DAVID

IPC: B23Q11/00 ,  B25D17/14

公开(公告)号：GB9418342D0

公开(公告)日：1994-11-02

申请号：GB9418342

申请日：1994-09-12

Applicant: STONE DAVID

公开(公告)号：CA2042318A1

公开(公告)日：1992-10-11

申请号：CA2042318

申请日：1991-05-10

Applicant: MACADAM ANDREW J ,  MINOR PHILIP D ,  STONE DAVID M ,  ALMOND JEFFREY W

Inventor： MACADAM ANDREW J ,  MINOR PHILIP D ,  STONE DAVID M ,  ALMOND JEFFREY W

IPC: A61K39/00 ,  A61K39/13 ,  C07K14/105 ,  C12N7/01 ,  C12N7/04 ,  C12N15/43

Abstract: ATTENUATED VIRUSES An attenuated poliovirus in which the 5' non-coding region of the genome is: (a) the 5' non-coding region of poliovirus type 3 Leon strain modified by the provision of the bases uracil and adenine at positions 472 and 537 thereof respectively, or (b) the 5' non-coding region of another poliovirus modified by the provision of the bases uracil and adenine at respective positions corresponding to position 472 and 537 of the 5' non-coding region of poliovirus type 3 Leon strain.

公开(公告)号：GB9117558D0

公开(公告)日：1991-10-02

申请号：GB9117558

申请日：1991-08-14

Applicant: STONE DAVID W

公开(公告)号：GB189509739A

公开(公告)日：1896-03-28

申请号：GB189509739D

申请日：1895-05-16

Applicant: STONE DAVID WILLIAM ,  CHAPLIN BERTRAM

Inventor： STONE DAVID WILLIAM ,  CHAPLIN BERTRAM

公开(公告)号：WO2017185122A1

公开(公告)日：2017-11-02

申请号：PCT/AU2016/050316

申请日：2016-04-29

Applicant: STONE, David

Inventor： STONE, David

IPC: B41J29/36 ,  B41J2/00

CPC classification number: B41J29/02 ,  B41J11/002 ,  B41J29/36

Abstract: This invention relates to a printing method and apparatus for implementing the method and, in particular, a method of performing ultra-violet print techniques for altering the appearance of a surface of a medium using solvent-free, UV-curable ink. The apparatus includes an ink- discharging print head that direct ink at a surface to be treated and a diode that directs UV radiation at the surface in a frequency range selected for causing curing of the ink. The apparatus preferably also contains a marking detector that locates undesired markings on the surface for obliteration using the ink.

Abstract translation: 本发明涉及一种用于实施该方法的印刷方法和设备，具体涉及一种使用无溶剂，无溶剂，无溶剂，无溶剂，无溶剂， UV固化油墨。 该设备包括将墨水引导到待处理表面的排墨打印头和在选定用于使墨固化的频率范围内的表面处引导UV辐射的二极管。 该设备最好还包含一个标记检测器，该标记检测器在表面上定位不希望的标记用于使用墨水进行消除。

公开(公告)号：WO2013066764A3

公开(公告)日：2014-08-21

申请号：PCT/US2012062218

申请日：2012-10-26

Applicant: MERCK SHARP & DOHME ,  LOBODA ANDREY ,  NEBOZHYN MICHAEL ,  PODTELEZHNIKOV ALEXEI ,  STONE DAVID J ,  TANIS KEITH ,  RAY WILLIAM J

Inventor： LOBODA ANDREY ,  NEBOZHYN MICHAEL ,  PODTELEZHNIKOV ALEXEI ,  STONE DAVID J ,  TANIS KEITH ,  RAY WILLIAM J

IPC: C12Q1/68 ,  A01K67/00 ,  G01N33/00

CPC classification number: C12Q1/6883 ,  A01K67/0275 ,  C12Q2600/158 ,  G01N33/6896

Abstract: Methods, biomarkers, and expression signatures are disclosed for assessing the disease progression of Alzheimer's disease (AD). In one embodiment, BioAge (biological age), NdStress (neurodegenerative stress), Alz (Alzheimer), and Inflame (inflammation) are used as biomarkers of AD progression. In another aspect, the invention comprises a gene signature for evaluating disease progression. In still another embodiment, methods for evaluating disease progression are provided. In yet another embodiment, the invention can be used to identify animal models for use in the development and evaluation of therapeutics for the treatment of AD.

Abstract translation: 公开了评估阿尔茨海默氏病（AD）疾病进展的方法，生物标志物和表达特征。 在一个实施方案中，使用BioAge（生物学年龄），NdStress（神经变性应激），Alz（阿尔茨海默）和Inflame（炎症））作为AD进展的生物标志物。 另一方面，本发明包括用于评估疾病进展的基因特征。 在另一个实施方案中，提供了评估疾病进展的方法。 在另一个实施方案中，本发明可用于鉴定用于开发和评估用于治疗AD的治疗剂的动物模型。