公开(公告)号：US10811736B2

公开(公告)日：2020-10-20

申请号：US16318826

申请日：2017-07-21

Applicant: HYDRO-QUÉBEC ,  TRANSFERT PLUS, S.E.C.

Inventor： Nicolas Delaporte ,  Diby Benjamin Ossonon ,  Karim Zaghib ,  Daniel Belanger

IPC: H01M10/54 ,  H01M4/131 ,  H01M4/136 ,  H01M4/62

Abstract: A process for recycling an electrode material comprising graphene and an electrochemically active material is described. The process comprises a step of adding, in any order, water and a non-miscible solvent to the electrode material, thereby forming a biphasic system comprising an organic phase and an aqueous phase; and a step of separating and filtering the organic phase to recover graphene. The process optionally comprises additional steps of washing, drying, and/or thermally treating. Also described are electrodes including the recycled graphene, as well as the electrochemical cells and their uses.

公开(公告)号：US20190288260A1

公开(公告)日：2019-09-19

申请号：US16318878

申请日：2017-07-21

Applicant: HYDRO-QUÉBEC ,  Transfert Plus, S.E.C.

Inventor： Nicolas DELAPORTE ,  Diby Benjamin OSSONON ,  Karim ZAGHIB ,  Daniel BELANGER

IPC: H01M2/16 ,  H01M2/14 ,  H01M4/62 ,  H01M10/0525 ,  H01M4/04

Abstract: This application describes a process for the preparation of flexible electrode-separator elements or assemblies, which includes the application of an electrode material on the separator. The electrode material comprises graphene, for instance produced by graphite exfoliation. The electrode-separator elements obtained by the process as well as their use in electrochemical cells are also described.

公开(公告)号：US20180138512A1

公开(公告)日：2018-05-17

申请号：US15576126

申请日：2016-01-04

Applicant: HYDRO-QUÉBEC ,  TRANSFERT PLUS, S.E.C.

Inventor： Daniel BÉLANGER ,  Nicolas DELAPORTE ,  Karim ZAGHIB

IPC: H01M4/62 ,  H01M4/58 ,  H01M4/485 ,  H01M4/36 ,  C25D11/00

CPC classification number: H01M4/628 ,  C25D11/00 ,  H01M4/366 ,  H01M4/485 ,  H01M4/5825 ,  H01M4/62 ,  H01M4/622 ,  H01M10/052 ,  H01M2300/004 ,  H01M2300/0082 ,  H01M2300/0085

Abstract: Described is a method or process for modifying the surface of carbon-coated electrochemically active materials such as complex oxides like olivine-type cathode materials. For instance, the surface of the carbon-coated powder material is modified to increase its hydrophobic characteristics. Also, specific groups may be grafted on the carbon surface of cathode material using the diazonium chemistry, for instance, by the spontaneous grafting of aryl ions generated in situ by the diazotization of an arylamine compound.

公开(公告)号：US20150107993A1

公开(公告)日：2015-04-23

申请号：US14396218

申请日：2013-04-18

Applicant: Transfert Plus, s.e.c.

Inventor： Ricardo Izquierdo ,  Philippe Juneau ,  Florent Lefèvre

IPC: G01N33/18 ,  G01N27/30 ,  G01N21/64

CPC classification number: G01N33/1866 ,  C12M21/02 ,  C12M23/16 ,  C12Q1/02 ,  G01N21/64 ,  G01N21/6486 ,  G01N27/30 ,  G01N33/1893 ,  G01N2033/184 ,  G01N2201/0628 ,  G01N2201/068 ,  G01N2520/00

Abstract: There are provided methods and apparatuses for evaluating water pollution. The apparatus comprises at least one light source for exciting or causing activity of at least one type of microorganism or biological material; at least one photodetector for detecting a level of fluorescent light; and a chip disposed between the at least one light source and the detector, the chip comprising at least one microfluidic channel disposed for being exposed to light from the at least one light source and dimensioned for receiving a composition comprising the at least one type of microorganism or biological material and a water sample to be evaluated.

Abstract translation: 提供了评估水污染的方法和设备。 该装置包括用于激发或引起至少一种类型的微生物或生物材料的活性的至少一个光源; 用于检测荧光水平的至少一个光电检测器; 以及设置在所述至少一个光源和所述检测器之间的芯片，所述芯片包括至少一个微流体通道，所述至少一个微流体通道被设置用于暴露于来自所述至少一个光源的光，并被设计成用于接收包含所述至少一种类型的微生物 或生物材料和要评估的水样。

公开(公告)号：US11780882B2

公开(公告)日：2023-10-10

申请号：US17239544

申请日：2021-04-23

Applicant: TRANSFERT PLUS, S.E.C.

Inventor： Richard Béliveau ,  Borhane Annabi ,  Michel Demeule ,  Alain Larocque ,  Jean-Christophe Currie ,  Cyndia Charfi

IPC: C07K7/08 ,  A61K47/64 ,  A61P35/00 ,  A61K31/337 ,  C07K1/06 ,  C07K14/00 ,  A61K38/00

CPC classification number: C07K7/08 ,  A61K31/337 ,  A61K47/64 ,  A61P35/00 ,  C07K1/061 ,  C07K14/001 ,  A61K38/00

Abstract: The present disclosure relates to peptide compounds and conjugate compounds, processes, methods and uses thereof for treating cancer. For example, the compounds can comprise compounds of formula













X1X2X3X4X5GVX6AKAGVX7NX8FKSESY
(SEQ ID NO: 1)


(I)






(X9)nGVX10AKAGVX11NX12FKSESY
(SEQ ID NO: 2)


(II)






YKX13LRRX14APRWDX15PLRDPALRX16X17L
(SEQ ID NO: 3)


(III)






YKX18LRR(X19)nPLRDPALRX20X21L
(SEQ ID NO: 4)


(IV)






IKLSGGVQAKAGVINMDKSESM
(SEQ ID NO: 5)


(V)






IKLSGGVQAKAGVINMFKSESY
(SEQ ID NO: 6)


(VI)






IKLSGGVQAKAGVINMFKSESYK
(SEQ ID NO: 7)


(VII)






GVQAKAGVINMFKSESY
(SEQ ID NO: 8)


(VIII)






GVRAKAGVRNMFKSESY
(SEQ ID NO: 9)


(IX)






GVRAKAGVRN(Nle)FKSESY
(SEQ ID NO: 10)


(X)






YKSLRRKAPRWDAPLRDPALRQLL
(SEQ ID NO: 11)


(XI)






YKSLRRKAPRWDAYLRDPALRQLL
(SEQ ID NO: 12)


(XII)






YKSLRRKAPRWDAYLRDPALRPLL
(SEQ ID NO: 13)


(XIII)











wherein X1 to X21 and n can have various different values
and wherein at least one protecting group and/or at least one labelling agent is optionally connected to said peptide compound at an N- and/or C-terminal end.

公开(公告)号：US20200157151A1

公开(公告)日：2020-05-21

申请号：US16616098

申请日：2018-05-24

Applicant: TRANSFERT PLUS, S.E.C.

Inventor： Richard BÉLIVEAU ,  Borhane ANNABI ,  Michel DEMEULE ,  Alain LAROCQUE ,  Jean-Christophe CURRIE ,  Sylvie LAMY

IPC: C07K14/195 ,  A61K47/64 ,  A61K47/66 ,  C07K7/08 ,  A61P29/00 ,  A61K31/12

Abstract: The present disclosure relates to peptide compounds and conjugate compounds, processes, methods and uses thereof for treating inflammation. For example, the compounds can comprise compounds; IKLSGGVQAKAGVINMDKSESM, formula (V) as set forth in SEQ ID NO: 5, GVRAKAGVRN(Nle)FKSESY, formula (X) as set forth in SEQ ID NO: 10 and YKSLRRK.APRWDAPLRDPALRQLL, formula (XI) as set forth in SEQ ID NO: 11 wherein at least one protecting group and/or at least one labelling agent is connected to said peptide compound at an N- and/or C-terminal end, for use in inhibiting or decreasing TNF-alpha-induced COX-2 expression in cells expression sortilin.

公开(公告)号：US20190288349A1

公开(公告)日：2019-09-19

申请号：US16318826

申请日：2017-07-21

Applicant: HYDRO-QUÉBEC ,  TRANSFERT PLUS, S.E.C.

Inventor： Nicolas DELAPORTE ,  Diby Benjamin OSSONON ,  Karim ZAGHIB ,  Daniel BELANGER

IPC: H01M10/54 ,  H01M4/136 ,  H01M4/131 ,  H01M4/62

Abstract: A process for recycling an electrode material comprising graphene and an electrochemically active material is described. The process comprises a step of adding, in any order, water and a non-miscible solvent to the electrode material, thereby forming a biphasic system comprising an organic phase and an aqueous phase; and a step of separating and filtering the organic phase to recover graphene. The process optionally comprises additional steps of washing, drying, and/or thermally treating. Also described are electrodes including the recycled graphene, as well as the electrochemical cells and their uses.

公开(公告)号：WO2018014137A1

公开(公告)日：2018-01-25

申请号：PCT/CA2017/050881

申请日：2017-07-21

Applicant: HYDRO-QUÉBEC ,  TRANSFERT PLUS, S.E.C.

Inventor： DELAPORTE, Nicolas ,  OSSONON, Diby Benjamin ,  ZAGHIB, Karim ,  BELANGER, Daniel

IPC: H01M4/139 ,  H01M10/052

Abstract: Ce document décrit un procédé pour la préparation d'éléments ou assemblages électrode-séparateur flexibles, qui inclus l'application d'un matériau d'électrode sur le séparateur. Le matériau d'électrode comprend du graphène, par exemple produit par exfoliation de graphite. Les éléments électrode-séparateur obtenus par le procédé de même que leur utilisation dans des cellules électrochimiques sont aussi décrits.

Abstract translation:

该文件描述了一个程序。 用于制备柔性电极组件或组件，其包括将电极材料施加到分离器。 电极材料包含石墨烯，例如通过石墨剥离产生。 通过处理过程获得的电除臭元件 即使它们在电化学电池中的使用也被描述。

公开(公告)号：WO2017088058A1

公开(公告)日：2017-06-01

申请号：PCT/CA2016/051379

申请日：2016-11-24

Applicant: TRANSFERT PLUS, S.E.C.

Inventor： BÉLIVEAU, Richard ,  ANNABI, Borhane ,  DEMEULE, Michel ,  LAROCQUE, Alain ,  CURRIE, Jean-christophe ,  CHARFI, Cyndia

IPC: C07K14/195 ,  A61K47/66 ,  A61P35/00 ,  C07C43/295 ,  C07D305/14 ,  C07H15/252 ,  C07K1/06 ,  C07K1/113 ,  C07K14/00 ,  C07K14/47 ,  C07K17/00 ,  C07K7/08 ,  C40B40/10 ,  A61K9/127

CPC classification number: C07K7/08 ,  A61K9/127 ,  A61K9/5107 ,  A61K38/00 ,  C07C43/295 ,  C07D305/14 ,  C07K1/113 ,  C07K7/083 ,  C07K14/00 ,  C40B40/10 ,  Y02P20/55

Abstract: The present disclosure relates to peptide compounds and conjugate compounds, processes, methods and uses thereof for treating cancer and increasing cellular internalization of said peptide compounds. The peptide compounds are selected from the following group consisting of; GVRAKAGVRNMFKSESY as set forth in SEQ ID NO: 9; GVRAKAGVRN(Nle)FKSESY as set forth in SEQ ID NO: 10; and YKSLRRKAPRWDAPLRDPALRQLL as set forth in SEQ ID NO: 11; and wherein at least one protecting group and/or at least one labelling agent is connected to said peptide compound.

Abstract translation: 本公开涉及用于治疗癌症并增加所述肽化合物的细胞内化的肽化合物和缀合物化合物，其工艺，方法和用途。 肽化合物选自下组： 如SEQ ID NO：9所示的GVRAKAGVRNMFKSESY; 如SEQ ID NO：10所示的GVRAKAGVRN（Nle）FKSESY; 和如SEQ ID NO：11所示的YKSLRRKAPRWDAPLRDPALRQLL; 并且其中至少一个保护基团和/或至少一个标记试剂与所述肽化合物连接。

公开(公告)号：WO2013159189A1

公开(公告)日：2013-10-31

申请号：PCT/CA2013/000383

申请日：2013-04-18

Applicant: TRANSFERT PLUS, S.E.C.

Inventor： LEFÈVRE, Florent ,  IZQUIERDO, Ricardo ,  JUNEAU, Philippe

IPC: G01N21/76 ,  C12M1/12 ,  C12M1/34 ,  C12M1/42 ,  C12Q1/02 ,  G01N1/00 ,  G01N21/00 ,  G01N21/01 ,  G01N27/00

CPC classification number: G01N33/1866 ,  C12M21/02 ,  C12M23/16 ,  C12Q1/02 ,  G01N21/64 ,  G01N21/6486 ,  G01N27/30 ,  G01N33/1893 ,  G01N2033/184 ,  G01N2201/0628 ,  G01N2201/068 ,  G01N2520/00

Abstract: There are provided methods and apparatuses for evaluating water pollution. The apparatus comprises at least one light source for exciting or causing activity of at least one type of microorganism or biological material; at least one photodetector for detecting a level of fluorescent light; and a chip disposed between the at least one light source and the detector, the chip comprising at least one microfluidic channel disposed for being exposed to light from the at least one light source and dimensioned for receiving a composition comprising the at least one type of microorganism or biological material and a water sample to be evaluated.

Abstract translation: 提供了评估水污染的方法和设备。 该装置包括用于激发或引起至少一种类型的微生物或生物材料的活性的至少一个光源; 用于检测荧光水平的至少一个光电检测器; 以及设置在所述至少一个光源和所述检测器之间的芯片，所述芯片包括至少一个微流体通道，所述至少一个微流体通道被设置用于暴露于来自所述至少一个光源的光并被设计成用于接收包含所述至少一种类型的微生物 或生物材料和要评估的水样。