公开(公告)号：US20140039223A1

公开(公告)日：2014-02-06

申请号：US14110450

申请日：2011-12-06

Applicant: Florian Klasovsky ,  Thomas Haas ,  Thomas Tacke ,  Jan Christoph Pfeffer ,  Michael Rimbach ,  Michael Volland ,  Michiel Janssen ,  Roger Sheldon ,  Juergen Haberland

Inventor： Florian Klasovsky ,  Thomas Haas ,  Thomas Tacke ,  Jan Christoph Pfeffer ,  Michael Rimbach ,  Michael Volland ,  Michiel Janssen ,  Roger Sheldon ,  Juergen Haberland

IPC: C07C45/59

CPC classification number: C07C45/59 ,  C07D493/04

Abstract: The invention relates to a method for the oxidation of a primary or secondary alcohol, preferably to form an aldehyde or ketone, comprising the following steps: a) providing a catalyst composition comprising at least one compound containing a nitroxyl radical, at least one NO source, at least one carbon or mineral acid or an anhydride of a carbon or mineral acid; b) producing a reaction mixture by adding at least one primary or secondary alcohol and a gas comprising oxygen and optionally one or more than one solvent to the catalyst composition from step a) or step e); c) incubating the reaction mixture from step b) at a temperature of between 0 and 100° C. or at the boiling point of the solvent; d) simultaneously with or subsequent to step c): crystallizing the reaction product; and e) recovering the catalyst composition by removing the crystallized reaction product from the reaction mixture obtained in step d).

Abstract translation: 本发明涉及氧化伯醇或仲醇，优选形成醛或酮的方法，包括以下步骤：a）提供包含至少一种含有硝酰基的化合物的催化剂组合物，至少一种NO源 ，至少一种碳或无机酸或碳或无机酸的酸酐; b）通过从步骤a）或步骤e）向催化剂组合物中加入至少一种伯醇或仲醇和包含氧气和任选的一种或多种溶剂的气体产生反应混合物; c）在0-100℃的温度或溶剂的沸点下温育来自步骤b）的反应混合物; d）与步骤c）同时或之后步骤：使反应产物结晶; 和e）通过从步骤d）中获得的反应混合物中除去结晶的反应产物来回收催化剂组合物。

公开(公告)号：US08378127B2

公开(公告)日：2013-02-19

申请号：US13142883

申请日：2010-01-26

Applicant: Uwe Dingerdissen ,  Jan Pfeffer ,  Thomas Tacke ,  Thomas Haas ,  Harald Schmidt ,  Michael Volland ,  Michael Rimbach ,  Christian Lettmann ,  Roger Sheldon ,  Michiel Janssen

Inventor： Uwe Dingerdissen ,  Jan Pfeffer ,  Thomas Tacke ,  Thomas Haas ,  Harald Schmidt ,  Michael Volland ,  Michael Rimbach ,  Christian Lettmann ,  Roger Sheldon ,  Michiel Janssen

IPC: C07D493/02

CPC classification number: C07D493/04

Abstract: The invention relates to a method for producing 2,6-dioxabicyclo-(3.3.0)-octane-4,8-dione (I), comprising the oxidation of dianhydrohexitols (II-IV), or of corresponding hydroxy ketones, with an oxygen-containing gas in the presence of a catalyst composition, the reaction proceeding without the addition of halogen sources.

Abstract translation: 本发明涉及2,6-二氧杂二环 - （3.3.0） - 辛烷-4,8-​​二酮（I）的制备方法，其中包括二脱氧己氮醇（II-IV）或相应的羟基酮氧化， 含氧气体在催化剂组合物的存在下进行，反应进行而不添加卤素源。

公开(公告)号：US20110269977A1

公开(公告)日：2011-11-03

申请号：US13142883

申请日：2010-01-26

Applicant: Uwe Dingerdissen ,  Jan Pfeffer ,  Thomas Tacke ,  Thomas Haas ,  Harald Schmidt ,  Michael Volland ,  Michael Rimbach ,  Christian Lettmann ,  Roger Sheldon ,  Michiel Janssen

Inventor： Uwe Dingerdissen ,  Jan Pfeffer ,  Thomas Tacke ,  Thomas Haas ,  Harald Schmidt ,  Michael Volland ,  Michael Rimbach ,  Christian Lettmann ,  Roger Sheldon ,  Michiel Janssen

IPC: C07D493/04

CPC classification number: C07D493/04

Abstract: The invention relates to a method for producing 2,6-dioxabicyclo-(3.3.0)-octane-4,8-dione (I), comprising the oxidation of dianhydrohexitols (II-IV), or of corresponding hydroxy ketones, with an oxygen-containing gas in the presence of a catalyst composition, the reaction proceeding without the addition of halogen sources.

Abstract translation: 本发明涉及2,6-二氧杂二环 - （3.3.0） - 辛烷-4,8-​​二酮（I）的制备方法，其中包括二脱氧己氮醇（II-IV）或相应的羟基酮氧化， 含氧气体在催化剂组合物的存在下进行，反应进行而不添加卤素源。

公开(公告)号：US06821922B1

公开(公告)日：2004-11-23

申请号：US09404537

申请日：1999-09-24

Applicant: Thomas Tacke ,  Helmfried Krause ,  Hermanus G. J. Lansink Rotgerink ,  Francis Daly ,  Martin Reisinger ,  Helmut Mangold

Inventor： Thomas Tacke ,  Helmfried Krause ,  Hermanus G. J. Lansink Rotgerink ,  Francis Daly ,  Martin Reisinger ,  Helmut Mangold

IPC: B01J2358

CPC classification number: B01J37/0018 ,  B01J21/063 ,  B01J21/066 ,  B01J21/08 ,  B01J23/52 ,  B01J23/58 ,  B01J23/60 ,  B01J23/66 ,  B01J35/1014 ,  B01J35/1019 ,  B01J35/1038 ,  B01J35/1042 ,  C07C67/055 ,  C07C69/01 ,  C07C69/15

Abstract: Moldings based on pyrogenically produced mixed oxide having the following physicochemical parameters: External diameter 0.8-25 mm BET surface area 5-400 m2/g Pore Volume 0.2-1.8 ml/g Fracture strength 5 to 350 N Composition At least two oxides selected from the group SiO2, Al2O3, TiO 2 and ZrO2 in any desired combination but with the exception of SiO2/Al2O3 mixed oxides, in which > 75 wt. % of SiO2 is present. Other constituents

Abstract translation: 基于具有以下物理化学参数的热解产生的混合氧化物的模制品是通过根据需要将一种或多种化合物与一种或多种来自甲基纤维素，甲基羟乙基纤维素，蜡，聚乙二醇，硬脂酸镁和/或硬脂酸铝的化合物均化， 水，在70-150℃的温度下干燥产物，任选地粉碎干燥的产物以产生粉末，任选地压缩粉末以产生模制品并在400℃的温度下进行0.5至10小时的热处理 °至1200℃。然后用合适的催化活性组分掺杂这些模制品，用于使用气相法生产乙酸乙烯酯单体。

公开(公告)号：US06316383B1

公开(公告)日：2001-11-13

申请号：US09344488

申请日：1999-06-25

Applicant: Thomas Tacke ,  Peter Schinke ,  Hermanus Lansink Rotgerink ,  Helmfried Kraus

Inventor： Thomas Tacke ,  Peter Schinke ,  Hermanus Lansink Rotgerink ,  Helmfried Kraus

IPC: B01J2108

CPC classification number: B01J35/026 ,  B01J19/30 ,  B01J21/08 ,  B01J2219/30223 ,  B01J2219/30416 ,  B01J2219/30475 ,  B01J2219/312 ,  C07C67/055 ,  Y10T428/131 ,  Y10T428/1317 ,  C07C69/01 ,  C07C69/15

Abstract: Moldings based on silica having a hollow cylindrical configuration with internal reinforcing stays or spokes leading from an inner wall of a hollow cylinder to the center of the molding or in the form of miniliths having passageway channels therethrough, are produced by homogenizing silica with methyl hydroxyethyl cellulose, wax and/or polyethylene glycol. Water and optionally aqueous alkaline ammonia solution are added, and the mixture is subjected to kneading and forming, extruding, optionally cutting the extrudate to the desired length by means of a cutting device, drying at a temperature from 20 to 150° C., and annealing for a period from 30 minutes to 10 hours at a temperature of 400 to 1200° C. The moldings can be used as catalyst supports for the production of unsaturated esters from olefins, organic acids and oxygen in the gas phase and and can be used in particular for the production of vinyl acetate monomer.

Abstract translation: 基于二氧化硅的模制品具有中空圆柱形构造，其具有从中空圆柱体的内壁到模制中心或具有通道通道的微透镜形式的内部加强支柱或辐条，其通过用甲基羟乙基纤维素 ，蜡和/或聚乙二醇。 加入水和任选的碱性氨水溶液，将混合物进行捏合和成形，挤出，任选地通过切割装置将挤出物切割成所需长度，在20至150℃的温度下干燥，以及 在400〜1200℃的温度下退火30分钟〜10小时。成型体可以用作在气相中由烯烃，有机酸和氧气生产不饱和酯的催化剂载体，并且可以使用 特别是用于生产乙酸乙烯酯单体。

公开(公告)号：US06232511B1

公开(公告)日：2001-05-15

申请号：US09424979

申请日：1999-12-02

Applicant: Thomas Haas ,  Dahai Yu ,  Jorg Sauer ,  Dietrich Arntz ,  Andreas Freund ,  Thomas Tacke

Inventor： Thomas Haas ,  Dahai Yu ,  Jorg Sauer ,  Dietrich Arntz ,  Andreas Freund ,  Thomas Tacke

IPC: C07C2941

CPC classification number: C07C29/141 ,  C12C11/02 ,  C07C31/205

Abstract: A process for the production of 1,3-propanediol by heterogeneously catalyzed hydrogenation of 3-hydroxypropionaldehyde in an aqueous solution at 30 to 180° C., at a hydrogenation pressure of 5 to 300 bar and a pH value of 2.5 to 7.0, wherein ruthenium on an oxide support is used as the catalyst.

Abstract translation: 一种在30〜180℃，氢化压力为5〜300巴，pH值为2.5〜7.0的水溶液中，3-羟基丙醛异构催化氢化制备1,3-丙二醇的方法，其中 氧化物载体上的钌用作催化剂。

公开(公告)号：US06156933A

公开(公告)日：2000-12-05

申请号：US155660

申请日：1999-02-18

Applicant: Martyn Poliakoff ,  Thomas M. Swan ,  Thomas Tacke ,  Martin G. Hitzler ,  Stephen K. Ross ,  Stefan Wieland

Inventor： Martyn Poliakoff ,  Thomas M. Swan ,  Thomas Tacke ,  Martin G. Hitzler ,  Stephen K. Ross ,  Stefan Wieland

IPC: B01J3/00 ,  C07B35/02 ,  C07B43/04 ,  C07B61/00 ,  C07C29/132 ,  C07C29/141 ,  C07C29/145 ,  C07C29/20 ,  C07C45/58 ,  C07C209/36 ,  C07D317/66 ,  C07C209/00 ,  C07C5/00 ,  C07C37/00

CPC classification number: C07C29/145 ,  B01J3/008 ,  C07B35/02 ,  C07B43/04 ,  C07C209/36 ,  C07C29/132 ,  C07C29/141 ,  C07C29/20 ,  C07C45/58 ,  C07D317/66 ,  C07C2101/14 ,  Y02P20/544

Abstract: Process for the selective hydrogenation of alphatic or aromatic substrates under supercritical or near critical conditions. Hydrogenation is effected using a heterogeneous catalyst in a continuous flow reactor containing a supercritical or near critical reaction medium and selectively of product formation is achieved by varying one or more of the temperature, pressure, catalyst and flow rate.

Abstract translation: PCT No.PCT / GB97 / 01014 Sec。 371日期1999年2月18日 102（e）1999年2月18日PCT 1997年4月11日PCT PCT。 出版物WO97 / 38955 日期1997年10月23日在超临界或接近临界条件下选择性氢化脂肪或芳香族底物的方法。 在包含超临界或近临界反应介质的连续流动反应器中使用非均相催化剂进行氢化，并且通过改变一种或多种温度，压力，催化剂和流速来实现产物形成的选择性。

公开(公告)号：US5981767A

公开(公告)日：1999-11-09

申请号：US102758

申请日：1998-06-23

Applicant: Herbert Tanner ,  Karlheinz Drauz ,  Gerhard Sator ,  Horst Bethge ,  Roland Moller ,  Frank Hubner ,  Thomas Tacke ,  Claus Rehren

Inventor： Herbert Tanner ,  Karlheinz Drauz ,  Gerhard Sator ,  Horst Bethge ,  Roland Moller ,  Frank Hubner ,  Thomas Tacke ,  Claus Rehren

IPC: A61K31/385 ,  A61P25/00 ,  A61P25/04 ,  A61P29/00 ,  C07D339/04 ,  C07D333/24

CPC classification number: C07D339/04 ,  Y02P20/544

Abstract: The present invention is relative to a method of producing dry thioctic acid in which a raw material in which concentrated thioctic acid is present is treated with liquid or supercritical CO.sub.2, thus yielding thioctic acid with low residual solvent contents in a simple industrial method.

Abstract translation: 本发明涉及一种生产干硫辛酸的方法，其中存在浓硫硫酸的原料用液体或超临界CO 2处理，从而以简单的工业方法产生具有低残留溶剂含量的硫辛酸。

公开(公告)号：US08927773B2

公开(公告)日：2015-01-06

申请号：US13820803

申请日：2011-08-23

Applicant: Florian Klasovsky ,  Jan Christoph Pfeffer ,  Thomas Tacke ,  Thomas Haas ,  Andreas Martin ,  Jens Deutsch ,  Angela Koeckritz

Inventor： Florian Klasovsky ,  Jan Christoph Pfeffer ,  Thomas Tacke ,  Thomas Haas ,  Andreas Martin ,  Jens Deutsch ,  Angela Koeckritz

IPC: C07C209/00 ,  C07C209/16 ,  C07C213/02 ,  C07D493/04

CPC classification number: C07C209/16 ,  C07C213/02 ,  C07D493/04

Abstract: The invention relates to a process for preparing primary amines which comprises the process steps A) provision of a solution of a secondary alcohol in a fluid, nongaseous phase, B) contacting of the phase with free ammonia and/or at least one ammonia-releasing compound and a homogeneous catalyst and optionally C) isolation of the primary amine formed in process step B), characterized in that the volume ratio of the volume of the liquid phase to the volume of the gas phase in process step B is greater than or equal to 0.25, and/or in that the ammonia is used in process step B) in a molar ratio based on the hydroxyl groups in the secondary alcohol of at least 5:1.

Abstract translation: 本发明涉及一种制备伯胺的方法，其包括以下工艺步骤：A）将仲醇在流体，非气相中提供，B）使相与游离氨和/或至少一种氨释放的相接触 化合物和均相催化剂，并任选地C）分离方法步骤B）中形成的伯胺，其特征在于在工艺步骤B中液相的体积与气相体积的体积比大于或等于 至0.25，和/或其中氨在工艺步骤B）中以基于仲醇中羟基的摩尔比至少为5:1。

公开(公告)号：US08809576B2

公开(公告)日：2014-08-19

申请号：US13141456

申请日：2010-02-01

Applicant: Alexander Schraven ,  Thomas Tacke ,  Thomas Haas ,  Christoph Kobler ,  Dieter Buss ,  Axel Ronneburg ,  Olivier Zehnacker

Inventor： Alexander Schraven ,  Thomas Tacke ,  Thomas Haas ,  Christoph Kobler ,  Dieter Buss ,  Axel Ronneburg ,  Olivier Zehnacker

IPC: C07F9/22

CPC classification number: C07C51/02 ,  C07C59/00 ,  C07C55/10 ,  C07C59/01 ,  C07C55/00 ,  C07C65/00 ,  C07C59/08 ,  C07C63/00

Abstract: The invention relates to an improved method for releasing an organic acid, preferably a carbon, sulfone or phosphone acid, particularly an alpha or beta hydroxycarbon acid, from the ammonia salt thereof by releasing and removing ammoniac and simultaneous extraction of the released acid, having an amine as a suitable extraction means from the aqueous phase. This method corresponds to a reactive extraction. The reactive extraction of an organic acid from the aqueous ammonia salt solution thereof can be significantly improved by the use of a strip medium or carrier gas, such as nitrogen, air, water vapor or inert gases such as argon. The released ammoniac is removed from the aqueous solution by the continuous gas flow and can be resupplied into a production process. The free acid can be obtained by a method such as distillation, rectification, crystallization, reextraction, chromatography, adsorption or by a membrane method from the extraction means.

Abstract translation: 本发明涉及通过释放和除去氨和同时提取释放的酸的有机酸，优选碳，砜或膦酸，特别是α或β羟基碳酸从其氨盐中释放的改进方法，其具有 胺作为来自水相的合适的提取方法。 该方法对应于反应萃取。 通过使用带状介质或载气如氮气，空气，水蒸汽或惰性气体如氩气，可以显着地改善有机酸从其氨水溶液中的反应萃取。 通过连续气流将释放的氨水从水溶液中除去，并且可以再供给到生产过程中。 游离酸可以通过蒸馏，精馏，结晶，再萃取，色谱法，吸附法或从提取方法通过膜法等方法得到。