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公开(公告)号：WO2003064628A3
公开(公告)日：2003-08-07
申请号：PCT/US2003/003401
申请日：2003-02-03
Applicant: CURAGEN CORPORATION , ALSOBROOK, John, P., II , BADER, Joel, S. , BERGHS, Constance , BURGESS, Catherine, E. , CASMAN, Stacie, J. , CATTERTON, Elina , CHAUDHURI, Amitabha , EDINGER, Shlomit, R. , ELLERMAN, Karen , GERLACH, Valerie, L. , GORMAN, Linda , GUO, Xiaojia , HERRMANN, John, L. , JI, Weizhen , KHRAMTSOV, Nikolai, V. , LI, Li , MILLER, Charles, E. , ORT, Tatiana , PATTURAJAN, Meera , RASTELLI, Luca , RIEGER, Daniel, K. , SHENOY, Suresh, G. , SHIMKETS, Richard, A. , SPYTEK, Kimberly, A. , VERNET, Corine, A., M. , ZHONG, Haihong , ZHONG, Mei
Inventor： ALSOBROOK, John, P., II , BADER, Joel, S. , BERGHS, Constance , BURGESS, Catherine, E. , CASMAN, Stacie, J. , CATTERTON, Elina , CHAUDHURI, Amitabha , EDINGER, Shlomit, R. , ELLERMAN, Karen , GERLACH, Valerie, L. , GORMAN, Linda , GUO, Xiaojia , HERRMANN, John, L. , JI, Weizhen , KHRAMTSOV, Nikolai, V. , LI, Li , MILLER, Charles, E. , ORT, Tatiana , PATTURAJAN, Meera , RASTELLI, Luca , RIEGER, Daniel, K. , SHENOY, Suresh, G. , SHIMKETS, Richard, A. , SPYTEK, Kimberly, A. , VERNET, Corine, A., M. , ZHONG, Haihong , ZHONG, Mei
Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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公开(公告)号：WO2003064628A2
公开(公告)日：2003-08-07
申请号：PCT/US2003/003401
申请日：2003-02-03
Applicant: CURAGEN CORPORATION , ALSOBROOK, John, P., II , BADER, Joel, S. , BERGHS, Constance , BURGESS, Catherine, E. , CASMAN, Stacie, J. , CATTERTON, Elina , CHAUDHURI, Amitabha , EDINGER, Shlomit, R. , ELLERMAN, Karen , GERLACH, Valerie, L. , GORMAN, Linda , GUO, Xiaojia , HERRMANN, John, L. , JI, Weizhen , KHRAMTSOV, Nikolai, V. , LI, Li , MILLER, Charles, E. , ORT, Tatiana , PATTURAJAN, Meera , RASTELLI, Luca , RIEGER, Daniel, K. , SHENOY, Suresh, G. , SHIMKETS, Richard, A. , SPYTEK, Kimberly, A. , VERNET, Corine, A., M. , ZHONG, Haihong , ZHONG, Mei
Inventor： ALSOBROOK, John, P., II , BADER, Joel, S. , BERGHS, Constance , BURGESS, Catherine, E. , CASMAN, Stacie, J. , CATTERTON, Elina , CHAUDHURI, Amitabha , EDINGER, Shlomit, R. , ELLERMAN, Karen , GERLACH, Valerie, L. , GORMAN, Linda , GUO, Xiaojia , HERRMANN, John, L. , JI, Weizhen , KHRAMTSOV, Nikolai, V. , LI, Li , MILLER, Charles, E. , ORT, Tatiana , PATTURAJAN, Meera , RASTELLI, Luca , RIEGER, Daniel, K. , SHENOY, Suresh, G. , SHIMKETS, Richard, A. , SPYTEK, Kimberly, A. , VERNET, Corine, A., M. , ZHONG, Haihong , ZHONG, Mei
IPC: C12N
CPC classification number: C12Q1/6876 , A61K38/00 , C07K14/47 , C12Q2600/156
Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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公开(公告)号：WO2003064589A3
公开(公告)日：2003-08-07
申请号：PCT/US2002/024483
申请日：2002-08-02
Applicant: CURAGEN CORPORATION , KEKUDA, Ramesh , MILLER, Charles, E. , PATTURAJAN, Meera , PENA, Carol, E., A. , RIEGER, Daniel, K. , SHIMKETS, Richard, A. , ZERHUSEN, Bryan, D. , LI, Li , JI, Weizhen , PADIGARU, Muralidhara , CASMAN, Stacie, J. , VOSS, Edward, Z. , BOLDOG, Ferenc, L. , GORMAN, Linda , LEITE, Mario, W. , VERNET, Corine, A., M. , ANDERSON, David, W. , GUO, Xiaojia , ZHONG, Mei , GERLACH, Valerie, L. , HJALT, Tord , RASTELLI, Luca , SPYTEK, Kimberley, A. , EDINGER, Shlomit, R. , ELLERMAN, Karen , MALYANKAR, Uriel, M. , MACDOUGALL, John, R. , STONE, David, J. , ALSOBROOK, John, P., II , LEPLEY, Denise, M. , BURGESS, Catherine, E. , WOLENC, Adam, R. , SMITHSON, Glennda
Inventor： KEKUDA, Ramesh , MILLER, Charles, E. , PATTURAJAN, Meera , PENA, Carol, E., A. , RIEGER, Daniel, K. , SHIMKETS, Richard, A. , ZERHUSEN, Bryan, D. , LI, Li , JI, Weizhen , PADIGARU, Muralidhara , CASMAN, Stacie, J. , VOSS, Edward, Z. , BOLDOG, Ferenc, L. , GORMAN, Linda , LEITE, Mario, W. , VERNET, Corine, A., M. , ANDERSON, David, W. , GUO, Xiaojia , ZHONG, Mei , GERLACH, Valerie, L. , HJALT, Tord , RASTELLI, Luca , SPYTEK, Kimberley, A. , EDINGER, Shlomit, R. , ELLERMAN, Karen , MALYANKAR, Uriel, M. , MACDOUGALL, John, R. , STONE, David, J. , ALSOBROOK, John, P., II , LEPLEY, Denise, M. , BURGESS, Catherine, E. , WOLENC, Adam, R. , SMITHSON, Glennda
IPC: C07K14/47
Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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公开(公告)号：WO2003064589A2
公开(公告)日：2003-08-07
申请号：PCT/US2002/024483
申请日：2002-08-02
Applicant: CURAGEN CORPORATION , KEKUDA, Ramesh , MILLER, Charles, E. , PATTURAJAN, Meera , PENA, Carol, E., A. , RIEGER, Daniel, K. , SHIMKETS, Richard, A. , ZERHUSEN, Bryan, D. , LI, Li , JI, Weizhen , PADIGARU, Muralidhara , CASMAN, Stacie, J. , VOSS, Edward, Z. , BOLDOG, Ferenc, L. , GORMAN, Linda , LEITE, Mario, W. , VERNET, Corine, A., M. , ANDERSON, David, W. , GUO, Xiaojia , ZHONG, Mei , GERLACH, Valerie, L. , HJALT, Tord , RASTELLI, Luca , SPYTEK, Kimberley, A. , EDINGER, Shlomit, R. , ELLERMAN, Karen , MALYANKAR, Uriel, M. , MACDOUGALL, John, R. , STONE, David, J. , ALSOBROOK, John, P., II , LEPLEY, Denise, M. , BURGESS, Catherine, E. , MAJUMDER, Kumud , WOLENC, Adam, R. , SMITHSON, Glennda
Inventor： KEKUDA, Ramesh , MILLER, Charles, E. , PATTURAJAN, Meera , PENA, Carol, E., A. , RIEGER, Daniel, K. , SHIMKETS, Richard, A. , ZERHUSEN, Bryan, D. , LI, Li , JI, Weizhen , PADIGARU, Muralidhara , CASMAN, Stacie, J. , VOSS, Edward, Z. , BOLDOG, Ferenc, L. , GORMAN, Linda , LEITE, Mario, W. , VERNET, Corine, A., M. , ANDERSON, David, W. , GUO, Xiaojia , ZHONG, Mei , GERLACH, Valerie, L. , HJALT, Tord , RASTELLI, Luca , SPYTEK, Kimberley, A. , EDINGER, Shlomit, R. , ELLERMAN, Karen , MALYANKAR, Uriel, M. , MACDOUGALL, John, R. , STONE, David, J. , ALSOBROOK, John, P., II , LEPLEY, Denise, M. , BURGESS, Catherine, E. , MAJUMDER, Kumud , WOLENC, Adam, R. , SMITHSON, Glennda
IPC: C12N
CPC classification number: C07K14/705 , A61K38/00
Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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公开(公告)号：WO0246229A3
公开(公告)日：2003-07-10
申请号：PCT/US0146530
申请日：2001-12-05
Applicant: CURAGEN CORP , CASMAN STACIE J , PADIGARU MURALIDHARA , BURGESS CATHERINE E , SHIMKETS RICHARD A , SPYTEK KIMBERLY A , GILBERT JENNIFER A , MAYOTTE JANE E , BAUMGARTNER JASON C , MISHRA VISHNU , VERNET CORINE A M , DICKINSON KEVIN S , BALLINGER ROBERT A , WOLENC ADAM R
Inventor： CASMAN STACIE J , PADIGARU MURALIDHARA , BURGESS CATHERINE E , SHIMKETS RICHARD A , SPYTEK KIMBERLY A , GILBERT JENNIFER A , MAYOTTE JANE E , BAUMGARTNER JASON C , MISHRA VISHNU , VERNET CORINE A M , DICKINSON KEVIN S , BALLINGER ROBERT A , WOLENC ADAM R
CPC classification number: C07K14/705 , A61K38/00
Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these human nucleic acids and proteins.
Abstract translation: 本文公开了编码新型多肽的核酸序列。 还公开了由这些核酸序列编码的多肽，以及免疫特异性结合多肽的抗体以及上述多肽，多核苷酸或抗体的衍生物，变体，突变体或片段。 本发明还公开了用于诊断，治疗和预防涉及这些人核酸和蛋白质中的任何一种的病症的治疗，诊断和研究方法。
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Patent Agency Ranking
公开(公告)号：WO0200691A3
公开(公告)日：2003-02-27
申请号：PCT/US0120510
申请日：2001-06-27
Applicant: CURAGEN CORP , VERNET CORINE A M , TCHERNEV VELIZAR , PATTURAJAN MEERA , MALYANKAR URIEL M , GUSEV VLADIMIR , HERRMANN JOHN L , MACDOUGALL JOHN R , RASTELLI LUCA , ZHONG HAIHONG , SPYTEK KIMBERLY A , SHENOY SURESH , GERLACH VALERIE L , GANGOLLI ESHA A , STONE DAVID J , SMITHSON GLENNDA
Inventor： VERNET CORINE A M , TCHERNEV VELIZAR , PATTURAJAN MEERA , MALYANKAR URIEL M , GUSEV VLADIMIR , HERRMANN JOHN L , MACDOUGALL JOHN R , RASTELLI LUCA , ZHONG HAIHONG , SPYTEK KIMBERLY A , SHENOY SURESH , GERLACH VALERIE L , GANGOLLI ESHA A , STONE DAVID J , SMITHSON GLENNDA
IPC: G01N33/50 , A61K38/00 , A61K39/395 , A61K47/48 , A61K48/00 , A61P1/04 , A61P1/14 , A61P3/00 , A61P3/04 , A61P3/10 , A61P7/00 , A61P9/02 , A61P9/04 , A61P9/10 , A61P9/12 , A61P11/06 , A61P13/00 , A61P13/08 , A61P19/08 , A61P19/10 , A61P25/00 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61P27/00 , A61P27/02 , A61P29/00 , A61P31/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P33/02 , A61P35/00 , A61P37/04 , A61P37/08 , C07K14/47 , C07K14/705 , C07K16/18 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/36 , C12N15/09 , C12N15/12 , C12P21/08 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C12N15/85
CPC classification number: C12N9/2462 , A61K47/6829 , A61K47/6851 , A61K47/6869 , A61K2039/505 , C07K14/47 , C07K14/705 , C07K16/18 , C12N2799/026
Abstract: Disclosed herein are nucleic acid sequences. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
Abstract translation: 本文公开了核酸序列。 还公开了由这些核酸序列编码的多肽，以及免疫特异性结合多肽的抗体以及上述多肽，多核苷酸或抗体的衍生物，变体，突变体或片段。 本发明还公开了用于诊断，治疗和预防与这些新型人核酸和蛋白质中的任一种相关的病症的治疗，诊断和研究方法。
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公开(公告)号：WO2003000842A3
公开(公告)日：2003-01-03
申请号：PCT/US2002/017443
申请日：2002-06-04
Applicant: CURAGEN CORPORATION , AGEE, Michele, L. , ANDERSON, David, W. , BERGHS, Constance , CASMAN, Stacie, J. , CATTERTON, Elina , DIPIPPO, Vincent, A. , EDINGER, Shlomit, R. , EISEN, Andrew , ELLERMAN, Karen , GANGOLLI, Esha, A. , GERLACH, Valerie, L. , GORMAN, Linda , GUO, Xiaojia , HERRMANN, John, L. , HJALT, Tord , JI, Weizhen , KEKUDA, Ramesh , KHRAMTSOV, Nikolai, V. , LI, Li , LIU, Xiaohong , MALYANKAR, Uriel, M. , MILLER, Charles, E. , MILLET, Isabelle , ORT, Tatiana , PADIGARU, Muralidhara , PATTURAJAN, Meera , PENA, Carol, E., A. , RASTELLI, Luca , RIEGER, Daniel, K. , ROTHENBERG, Mark, E. , SHENOY, Suresh, G. , SHIMKETS, Richard, A. , SMITHSON, Glennda , SPADERNA, Steven, K. , SPYTEK, Kimberly, A. , STONE, David, J. , VERNET, Corine, A., M. , ZHONG, Haihong , ZHONG, Mei , ALSOBROOK, John, P., II , BURGESS, Catherine, E. , LEPLEY, Denise, M.
Inventor： AGEE, Michele, L. , ANDERSON, David, W. , BERGHS, Constance , CASMAN, Stacie, J. , CATTERTON, Elina , DIPIPPO, Vincent, A. , EDINGER, Shlomit, R. , EISEN, Andrew , ELLERMAN, Karen , GANGOLLI, Esha, A. , GERLACH, Valerie, L. , GORMAN, Linda , GUO, Xiaojia , HERRMANN, John, L. , HJALT, Tord , JI, Weizhen , KEKUDA, Ramesh , KHRAMTSOV, Nikolai, V. , LI, Li , LIU, Xiaohong , MALYANKAR, Uriel, M. , MILLER, Charles, E. , MILLET, Isabelle , ORT, Tatiana , PADIGARU, Muralidhara , PATTURAJAN, Meera , PENA, Carol, E., A. , RASTELLI, Luca , RIEGER, Daniel, K. , ROTHENBERG, Mark, E. , SHENOY, Suresh, G. , SHIMKETS, Richard, A. , SMITHSON, Glennda , SPADERNA, Steven, K. , SPYTEK, Kimberly, A. , STONE, David, J. , VERNET, Corine, A., M. , ZHONG, Haihong , ZHONG, Mei , ALSOBROOK, John, P., II , BURGESS, Catherine, E. , LEPLEY, Denise, M.
IPC: C12N9/00
Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases.
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公开(公告)号：WO0162928A3
公开(公告)日：2002-12-05
申请号：PCT/US0106151
申请日：2001-02-26
Applicant: CURAGEN CORP , VERNET CORINE A M , FERNANDES ELMA , SHIMKETS RICHARD A , MACDOUGALL JOHN , SPADERNA STEVEN K
Inventor： VERNET CORINE A M , FERNANDES ELMA , SHIMKETS RICHARD A , MACDOUGALL JOHN , SPADERNA STEVEN K
IPC: A61K38/00 , A61K48/00 , C07K14/47 , C07K14/81 , C12N9/12 , C12N15/12 , C12N15/54 , A61K38/17 , C07K16/18 , C07K16/40 , C12Q1/68 , G01N33/53 , G01N33/68
CPC classification number: C12N9/1205 , A61K38/00 , A61K48/00 , C07K14/47 , C07K14/811
Abstract: The present invention provides novel isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
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公开(公告)号：WO2002094870A2
公开(公告)日：2002-11-28
申请号：PCT/US2001/051580
申请日：2001-11-02
Applicant: CURAGEN CORPORATION , GROSSE, William, M. , MACDOUGALL, John, R. , SMITHSON, Glennda , MILLET, Isabelle , STONE, David, J. , GUNTHER, Erik , ELLERMAN, Karen , ALSOBROOK, John, P., II , LEPLEY, Denise, M. , BURGESS, Catherine, E. , SPYTEK, Kimberly, A. , EDINGER, Schlomit, R. , GANGOLLI, Esha, A. , GORMAN, Linda , TAUPIER, Raymond, J., Jr. , LI, Li , GUO, Xiaojia , FERNANDES, Elma, R. , VERNET, Corine, A., M. , TCHERNEV, Velizar, T. , CASMAN, Stacie, J. , SHENOY, Suresh , MISHRA, Vishnu , FURTAK, Katarzyna , BAUMGARTNER, Jason, C. , COLMAN, Steven, D.
Inventor： GROSSE, William, M. , MACDOUGALL, John, R. , SMITHSON, Glennda , MILLET, Isabelle , STONE, David, J. , GUNTHER, Erik , ELLERMAN, Karen , ALSOBROOK, John, P., II , LEPLEY, Denise, M. , BURGESS, Catherine, E. , SPYTEK, Kimberly, A. , EDINGER, Schlomit, R. , GANGOLLI, Esha, A. , GORMAN, Linda , TAUPIER, Raymond, J., Jr. , LI, Li , GUO, Xiaojia , FERNANDES, Elma, R. , VERNET, Corine, A., M. , TCHERNEV, Velizar, T. , CASMAN, Stacie, J. , SHENOY, Suresh , MISHRA, Vishnu , FURTAK, Katarzyna , BAUMGARTNER, Jason, C. , COLMAN, Steven, D.
IPC: C07K14/47
Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
Abstract translation: 本文公开了编码新多肽的核酸序列。 还公开了由这些核酸序列编码的多肽，以及与多肽免疫特异性结合的抗体，以及前述多肽，多核苷酸或抗体的衍生物，变体，突变体或片段。 本发明进一步公开了诊断，治疗和预防涉及任何一种这些新型人核酸和蛋白质的疾病的治疗，诊断和研究方法。
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30.发明申请
公开(公告)号：WO2002090504A2
公开(公告)日：2002-11-14
申请号：PCT/US2002/014342
申请日：2002-05-02
Applicant: CURAGEN CORPORATION , ALSOBROOK, John, P., II , ANDERSON, David, W. , BOLDOG, Ferenc, L. , BURGESS, Catherine, E. , CASMAN, Stacie, J. , CHAPOVAL, Andrei , EDINGER, Schlomit , GERLACH, Valerie , GORMAN, Linda , GUNTHER, Erik , GUO, Xiaojia , KEKUDA, Ramesh , LEPLEY, Denise, M. , LI, Li , LIU, Xiaohong , MALYANKAR, Uriel, M. , MILLER, Charles, E. , MILLET, Isabelle , PADIGARU, Muralidhara , PATTURAJAN, Meera , PENA, Carol, E., A. , RIEGER, Daniel, K. , SHENOY, Suresh, G. , SHIMKETS, Richard, A. , SPYTEK, Kimberly, A. , TAUPIER, Raymond, J., Jr. , VERNET, Corine, A., M. , VOSS, Edward, Z. , ZERHUSEN, Bryan, D.
Inventor： ALSOBROOK, John, P., II , ANDERSON, David, W. , BOLDOG, Ferenc, L. , BURGESS, Catherine, E. , CASMAN, Stacie, J. , CHAPOVAL, Andrei , EDINGER, Schlomit , GERLACH, Valerie , GORMAN, Linda , GUNTHER, Erik , GUO, Xiaojia , KEKUDA, Ramesh , LEPLEY, Denise, M. , LI, Li , LIU, Xiaohong , MALYANKAR, Uriel, M. , MILLER, Charles, E. , MILLET, Isabelle , PADIGARU, Muralidhara , PATTURAJAN, Meera , PENA, Carol, E., A. , RIEGER, Daniel, K. , SHENOY, Suresh, G. , SHIMKETS, Richard, A. , SPYTEK, Kimberly, A. , TAUPIER, Raymond, J., Jr. , VERNET, Corine, A., M. , VOSS, Edward, Z. , ZERHUSEN, Bryan, D.
IPC: C12N
CPC classification number: C07K14/47 , A61K38/00 , C07K14/705
Abstract: Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids, polypeptides, or antibodies, or fragments thereof.
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