公开(公告)号：TW201521718A

公开(公告)日：2015-06-16

申请号：TW103138861

申请日：2010-08-20

Applicant: 逸達研究及發達展公司 ,  YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED

Inventor： 克林格爾 艾堤 ,  KLINGER, ETY

IPC: A61K31/195 ,  A61P37/00

CPC classification number: A61K9/0019 ,  A61K31/19 ,  A61K31/785 ,  A61K38/02 ,  A61K38/07 ,  A61K38/16

Abstract: 本發明係關於一種減輕罹患復發-緩解型多發性硬化之人類病患或曾經歷第一次臨床發作且確定為具高風險發展成臨床明確多發性硬化之病患復發-緩解型多發性硬化症狀之方法，該方法包含在七天期間對該人類病患投與三次皮下注射治療有效劑量格拉替雷(glatiramer)醋酸鹽，每次皮下注射間隔至少一天，藉此減輕病患之症狀。

Abstract in simplified Chinese: 本发明系关于一种减轻罹患复发-缓解型多发性硬化之人类病患或曾经历第一次临床发作且确定为具高风险发展成临床明确多发性硬化之病患复发-缓解型多发性硬化症状之方法，该方法包含在七天期间对该人类病患投与三次皮下注射治疗有效剂量格拉替雷(glatiramer)醋酸盐，每次皮下注射间隔至少一天，借此减轻病患之症状。

公开(公告)号：TWI477273B

公开(公告)日：2015-03-21

申请号：TW099128023

申请日：2010-08-20

Applicant: 逸達研究及發達展公司 ,  YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED

Inventor： 克林格爾 艾堤 ,  KLINGER, ETY

IPC: A61K31/195 ,  A61P37/00

CPC classification number: A61K9/0019 ,  A61K31/19 ,  A61K31/785 ,  A61K38/02 ,  A61K38/07 ,  A61K38/16

公开(公告)号：AU636608B2

公开(公告)日：1993-05-06

申请号：AU5514190

申请日：1990-05-17

Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED

Inventor： DAVID WALLACH ,  HARMUT ENGELMANN ,  DAN ADERKA ,  DANIELA NOVICK ,  MENACHEM RUBINSTEIN

IPC: G01N33/53 ,  A61K38/00 ,  A61K38/17 ,  A61K38/19 ,  A61K39/395 ,  A61P37/00 ,  C07K1/14 ,  C07K1/16 ,  C07K1/20 ,  C07K1/22 ,  C07K7/06 ,  C07K14/00 ,  C07K14/435 ,  C07K14/46 ,  C07K14/47 ,  C07K14/52 ,  C07K14/525 ,  C07K14/715 ,  C07K16/00 ,  C07K16/18 ,  C07K16/24 ,  C07K16/28 ,  C12N1/21 ,  C12N5/10 ,  C12N15/09 ,  C12N15/12 ,  C12N15/28 ,  C12N15/63 ,  C12P21/00 ,  C12P21/02 ,  C12P21/08 ,  C12R1/19 ,  C12R1/91 ,  G01N33/564 ,  G01N33/577

Abstract: Tumor Necrosis Factor (TNF) Binding Protein is isolated and substantially purified. It has the ability to inhibit the cytotoxic effect of TNF and/or to maintain its prolonged beneficial effects. TNF Binding Protein II and salts, functional derivatives, precursors and active fractions thereof can be used to antagonize the deleterious effects of TNP and to prolong its beneficial effects Polyclonal and monoclonal antibodies to the TNF Binding Protein II are produced. They be used as pharmaceutical agents and in diagnostic assays.

公开(公告)号：ES2006714T3

公开(公告)日：1993-04-01

申请号：ES87302951

申请日：1987-04-03

Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED

Inventor： BOHAK, ZVI ,  KADOURI, AVINOAM ,  MAROUDAS, GEORGE NICHOLAS

IPC: C02F3/10 ,  C12M3/04 ,  C12N5/00 ,  C12N5/02

Abstract: The invention relates to packing material for use in the cultivation of anchorage-dependent cells, which require a solid surface for proliferation. The packing material of the invention is provided in the form of units of curved sheet material (Figures 1 to 4), which individual units generally have a thickness of about 0.05 mm to 0.25 mm, the other dimensions being of the order of one to a few millimeter maximum dimensions. Various shapes can be used, such as twisted rectangles, segments of cylinders, convulated ribbons, twisted shapes, ring shape and the like.

公开(公告)号：AU631111B2

公开(公告)日：1992-11-19

申请号：AU2859789

申请日：1989-01-18

Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED

Inventor： ADI SHAMIR

IPC: G09C1/00 ,  G07F7/10 ,  H04L9/00 ,  H04L9/32

公开(公告)号：AU3187093A

公开(公告)日：1993-07-29

申请号：AU3187093

申请日：1993-01-19

Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED

Inventor： AVI KRIBUS ,  JACOB KARNI

IPC: F24J2/04 ,  B01J19/12 ,  F24J2/00 ,  F24S20/20

Abstract: A central solar receiver comprising a housing (1) with a window (6) for the admission of incident concentrated solar radiation, a volumetric solar absorber (30) within the housing (1) comprising a base body (31) holding an array of absorber members (32) spaced from each other and projecting from one face thereof with their free ends facing said window (6), means (33,42) for the injection of working fluid into the volumetric solar absorber (30) in flow directions which intersect the absorber members (32) and means (35,36) for the withdrawal of heated working fluid. The window (6) of the central solar receiver is a tubular frusto-conical body coaxial with the housing (1), whereby the receiver is adapted for operation at elevated pressure.

公开(公告)号：AU2960792A

公开(公告)日：1993-06-03

申请号：AU2960792

申请日：1992-11-24

Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED

Inventor： AVNER YAYON ,  DAVID GIVOL

IPC: C12N15/09 ,  A61K38/00 ,  C07K14/705 ,  C07K14/71 ,  C07K16/28 ,  C07K19/00 ,  C12N5/10 ,  C12N15/12 ,  C12P21/02 ,  C12R1/91

公开(公告)号：WO1995006116A1

公开(公告)日：1995-03-02

申请号：PCT/US1994009854

申请日：1994-08-26

Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED ,  RYCUS, Avigail ,  ZIPORI, Dov

Inventor： YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED ,  RYCUS, Avigail

IPC: C12N15/00

CPC classification number: C07K16/24 ,  C07K14/52 ,  C07K2317/34

Abstract: New mammalian proteins are disclosed, found in stromal cells and designated herein as stromalin. One such protein has been isolated from murine cells and two such proteins from human cells.

Abstract translation: 公开了新的哺乳动物蛋白质，其在基质细胞中发现并且在本文中被指定为基质蛋白。 已经从鼠细胞和人类细胞中分离了两种这样的蛋白质中的一种这样的蛋白质。

公开(公告)号：WO1995001799A1

公开(公告)日：1995-01-19

申请号：PCT/US1994007510

申请日：1994-07-06

Applicant: SHOSHAN, Herbert, Z. ,  RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. ,  YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED ,  ZAMIR, Nadav ,  EISENBACH, Michael ,  NAOR, Zvi

Inventor： SHOSHAN, Herbert, Z. ,  RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. ,  YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED

IPC: A61K37/02

CPC classification number: C12N5/0612 ,  A61K31/70 ,  A61K33/00 ,  A61K38/2242 ,  G01N33/5005 ,  G01N33/56966 ,  A61K2300/00

Abstract: A method and pharmaceutical composition for modulating sperm cell fertility. The modulating can be enhancement of sperm cells' fertility by contacting them with atrial natriuretic peptide (ANP), an agonist thereof, cGMP or a permeable analogue thereof or agents which raise the level of cGMP in cell. The modulation can be inhibition of sperm cell fertility and in this case the sperm cells are contacted with an antagonist of ANP or an agent which lowers the levels of, or inhibits formation of cGMP in cells.

Abstract translation: 用于调节精子细胞生育力的方法和药物组合物。 调节可以通过将它们与心房钠尿肽（ANP），其激动剂，cGMP或其可渗透类似物或提高细胞中cGMP水平的试剂接触来提高精子细胞的生育力。 调节可以是精子细胞生殖力的抑制，并且在这种情况下，精子细胞与ANP的拮抗剂或降低细胞中cGMP的水平或抑制cGMP形成的试剂接触。

公开(公告)号：EP2046366B1

公开(公告)日：2016-08-31

申请号：EP07766829.1

申请日：2007-06-28

Applicant: Yeda Research And Development Company Limited

Inventor： EISENBACH-SCHWARTZ, Michal ,  BUTOVSKY, Oleg

IPC: A61K35/12 ,  A61K35/14 ,  A61K35/15 ,  A61K35/17 ,  A61K38/02 ,  A61K38/07 ,  A61K38/10 ,  A61K38/16 ,  A61K38/20 ,  A61K39/00

CPC classification number: A61K39/0007 ,  A61K35/12 ,  A61K35/15 ,  A61K35/17 ,  A61K38/02 ,  A61K38/07 ,  A61K38/10 ,  A61K38/16 ,  A61K38/2026 ,  C07K5/10 ,  C07K7/00 ,  C07K14/5406 ,  C12N5/0636

Abstract: The invention provides methods and compositions for treatment of age-related macular degeneration, which comprises causing T cells that produce IL-4 to accumulate in the eye by administration of an agent such as Copolymer-1, IL-4, cells activated with IL-4, IL-13 or up to 20 ng/ml IFN-g, or a pathogenic self-antigen associated with a T-cell-mediated specific autoimmune disease of the eye or a peptide derived therefrom, and any combination of such agents.