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公开(公告)号：KR1020140055401A
公开(公告)日：2014-05-09
申请号：KR1020120122155
申请日：2012-10-31
Abstract: The present invention relates to a method for screening skin whitening substances, and more specifically, to a method for screening skin whitening substances comprising a step of treating a test substance on a melanin-producing cell; and a step of checking relative expression level of one or more proteins selected from a group consisting of tyrosinase, integrin alpha 6, and MITF in a cell treated with the test substance of the step.
Abstract translation: 本发明涉及一种用于筛选皮肤美白物质的方法，更具体地，涉及一种用于筛选皮肤美白物质的方法，包括在黑色素产生细胞上处理测试物质的步骤; 以及在用该步骤的测试物质处理的细胞中检查选自由酪氨酸酶，整联蛋白α6和MITF组成的组中的一种或多种蛋白质的相对表达水平的步骤。
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公开(公告)号：KR101384497B1
公开(公告)日：2014-04-10
申请号：KR1020110029587
申请日：2011-03-31
Applicant: (주)아모레퍼시픽
IPC: A61K36/484 , A61K36/48 , A61P25/28 , A61P25/00
CPC classification number: A61K31/35 , A61K31/366 , A61K36/48
Abstract: 본 발명은 쿠메스트롤 또는 쿠메스트롤을 포함하는 콩 추출물을 유효 성분으로 포함하여 지방 세포의 분화를 억제하며, 신체 면역을 증진시키고, 독성 물질을 해독하며, 퇴행성 신경 장애를 예방 또는 개선하는 조성물을 개시한다.
Abstract translation: 本发明涉及一种组合物，其包含作为活性成分的香草雌酚或含有香豆素的豆提取物，其中脂肪细胞分化被抑制，身体的免疫系统得到改善，有毒物质被清除，并且可以预防或改善神经变性疾病。
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公开(公告)号：KR1020110110054A
公开(公告)日：2011-10-06
申请号：KR1020110029587
申请日：2011-03-31
Applicant: (주)아모레퍼시픽
IPC: A61K36/484 , A61K36/48 , A61P25/28 , A61P25/00
CPC classification number: A61K31/35 , A61K31/366 , A61K36/48
Abstract: 본 발명은 쿠메스트롤 또는 쿠메스트롤을 포함하는 콩 추출물을 유효 성분으로 포함하여 지방 세포의 분화를 억제하며, 신체 면역을 증진시키고, 독성 물질을 해독하며, 퇴행성 신경 장애를 예방 또는 개선하는 조성물을 개시한다.
Abstract translation: 本发明涉及一种组合物，其包含作为活性成分的香草雌酚或含有香豆素的豆提取物，其中脂肪细胞分化被抑制，身体的免疫系统得到改善，有毒物质被清除，并且可以预防或改善神经变性疾病。
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公开(公告)号：KR1020100134381A
公开(公告)日：2010-12-23
申请号：KR1020090052982
申请日：2009-06-15
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A composition for promoting the alcoholysis inside a human body is provided to use a post-heating fermented tea extract as an active ingredient for reducing hangover. CONSTITUTION: A composition for promoting the alcoholysis contains a post-heating fermented tea extract using non-pathogenic microorganisms as an active ingredient. The non-pathogenic microorganisms are selected from the group consisting of yeast, lactobacillus, saccharomyces genus, bacillus genus, and aspergillus genus. The composition promotes the activity of alcohol dehydrogenase and acetaldehyde dehydrogenase.
Abstract translation: 目的：提供一种用于促进人体内醇解的组合物，使用后加热发酵茶提取物作为减少宿醉的活性成分。 构成：用于促进醇解的组合物包含使用非致病微生物作为活性成分的后加热发酵茶提取物。 非病原微生物选自酵母，乳杆菌属，酵母属，芽孢杆菌属和曲霉属。 该组合物促进醇脱氢酶和乙醛脱氢酶的活性。
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公开(公告)号：KR1020100127728A
公开(公告)日：2010-12-06
申请号：KR1020100049181
申请日：2010-05-26
Applicant: (주)아모레퍼시픽
CPC classification number: A61K36/48 , A23L2/52 , A23L33/105 , A61K2236/333 , A23V2200/30
Abstract: PURPOSE: A composition containing soybean extract isolated with low alcohol is provided to improve blood circulation and to treat obesity, diabetes, and hyperlipidemia. CONSTITUTION: A composition for improving blood circulation contains soybean extract isolating with 1-7% of C1-5 alcohol or fraction. The C1-5 alcohol is methanol, ethanol, isopropylalcohol, n-propylalcohol, n-butanol or isobutanol. The soybean extract or fraction contains adenosine. The fraction is an ethylacetate or butanol fraction. The composition suppresses thrombosis or cholesterol generation.
Abstract translation: 目的：提供含有用低分子量分离的大豆提取物的组合物，以改善血液循环和治疗肥胖症，糖尿病和高脂血症。 构成：用于改善血液循环的组合物含有用1-7％的C1-5醇或级分分离的大豆提取物。 C 1-5醇是甲醇，乙醇，异丙醇，正丙醇，正丁醇或异丁醇。 大豆提取物或级分含有腺苷。 馏分是乙酸乙酯或丁醇馏分。 该组合物抑制血栓形成或胆固醇的产生。
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Patent Agency Ranking
公开(公告)号：KR1020100010916A
公开(公告)日：2010-02-02
申请号：KR1020090067159
申请日：2009-07-23
CPC classification number: C12Q1/6883 , C12Q2600/158
Abstract: PURPOSE: A method for screening dynamic stimulation for improving skin function is provided to measure biochemical change against external stimulation and screen kind, form, size, intensity, and time of dynamic stimulation. CONSTITUTION: A method for screening dynamic stimulation for improving skin function comprises: a first step of performing repeatitive dynamic stimulation to skin; a second step of measuring biochemical change of skin by dynamic stimulation; and a third step of selecting useful dynamic stimulation based on biochemical change. The measurement is performed by measuring mRNA expression level of fibroblast-derived gene. In the third step, nerve growth factor, neurotrophin 3, TIMP 1, TrkA, TrkC, TGF alpha, TGF beta1, TGF beta2 or TGF beta3 gene is selected as dynamic stimulation.
Abstract translation: 目的：提供一种用于筛选动态刺激以改善皮肤功能的方法，以测量对外部刺激和屏幕种类，形态，大小，强度和动态刺激时间的生物化学变化。 构成：用于筛选动态刺激以改善皮肤功能的方法包括：对皮肤进行重复动态刺激的第一步骤; 通过动态刺激测量皮肤生化变化的第二步; 以及基于生物化学变化选择有用的动态刺激的第三步。 通过测量成纤维细胞衍生基因的mRNA表达水平进行测量。 在第三步中，选择神经生长因子，神经营养因子3，TIMP1，TrkA，TrkC，TGFα，TGFβ1，TGFβ2或TGFβ3基因作为动态刺激。
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公开(公告)号：KR1020070028902A
公开(公告)日：2007-03-13
申请号：KR1020050083666
申请日：2005-09-08
Applicant: (주)아모레퍼시픽
Abstract: A cosmetic composition for suppressing sebum comprising catechins and kaempferol is provided to reduce activity of PPAR-gamma(peroxisome proliferator-activated receptor gamma) and suppress production of sebum, so that acnes symptom is alleviated. The cosmetic composition for suppressing sebum comprises catechins and kaempferol derived from green tea leaf, wherein the catechin is selected from (-)EGCG(epigallocatechin gallate), (-)GCG(gallocatechin gallate), (-)ECG(epicatechin gallate), (-)CG(catechin gallate), (-)EGC(epigallocatechin), (-)GC(gallocatechin), (-)EC(epicatechin), (+)EC(epicatechin), (-)CA(catechin) and (+)CA(catechin). The mixing ratio of catechins and kaempferol is 1:0.1-10, and the amounts of catechins and kaempferol are 0.001-30 wt.% respectively based on the total weight of the composition.
Abstract translation: 提供了用于抑制含有儿茶素和山奈酚的皮脂的化妆品组合物，以降低PPAR-γ（过氧化物酶体增殖物激活受体γ）的活性并抑制皮脂的产生，从而减轻痤疮症状。 用于抑制皮脂的化妆品组合物包括来自绿茶叶的儿茶素和山奈酚，其中儿茶素选自（ - ）EGCG（表没食子儿茶素没食子酸酯），（ - ）GCG（没食子儿茶素没食子酸酯），（ - ）ECG（表儿茶素没食子酸酯），（ - ）CG（儿茶素没食子酸酯），（ - ）EGC（儿茶素没食子酸酯），（ - ）GC（gallocatechin），（ - ）EC（表儿茶素），（+）EC ）CA（儿茶素）。 儿茶素和山奈酚的混合比为1：0.1-10，儿茶素和山奈酚的含量分别为组合物总重量的0.001-30重量％。
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公开(公告)号：KR100692099B1
公开(公告)日：2007-03-12
申请号：KR1020060024862
申请日：2006-03-17
Applicant: (주)아모레퍼시픽
Abstract: A skin cosmetic composition is provided to inhibit activity of 3beta-hydroxysteroid dehydrogenase and metabolic pathway thereof, thereby decreasing dihydrotestosterone(DHT), which is a final metabolite and being effective for improving sebum metabolism or acne. The skin cosmetic composition for inhibiting activity of 3beta-hydroxysteroid dehydrogenase comprises 0.001-30 wt.% of at least one selected from the group consisting of epigallocatechingallate(EGCG), gallocatechingallate(GCG), quercetin, kaempferol and myricetin as an effective ingredient.
Abstract translation: 提供皮肤化妆品组合物以抑制3β-羟基类固醇脱氢酶及其代谢途径的活性，从而降低作为最终代谢物的二氢睾酮（DHT），并有效改善皮脂代谢或痤疮。 用于抑制3β-羟基类固醇脱氢酶活性的皮肤化妆品组合物包含0.001-30重量％的选自表没食子儿茶素没食子酸酯（EGCG），没食子儿茶素没食子酸酯（GCG），槲皮素，山奈酚和杨梅黄酮作为有效成分。
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公开(公告)号：KR102200014B1
公开(公告)日：2021-01-08
申请号：KR1020140053471
申请日：2014-05-02
Applicant: (주)아모레퍼시픽
Abstract: 본발명은쿠메스트롤을포함하는콩 추출물을유효성분으로포함하는갱년기질환의예방등에대한조성물에관한것으로, 보다상세하게는쿠메스트롤을포함하는발아발효콩추출물을포함하는갱년기질환의예방등에대한조성물에관한것이다.
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公开(公告)号：KR1020170010885A
公开(公告)日：2017-02-01
申请号：KR1020170009868
申请日：2017-01-20
Applicant: (주)아모레퍼시픽
IPC: A61K36/48 , A23L33/105 , A23L2/52
CPC classification number: A61K36/48 , A23L2/52 , A23L33/105 , A61K2236/333
Abstract: 본발명은저농도저급알코올로추출한콩 추출물또는그 분획물을함유하는조성물에관한것이다. 상기조성물은혈액순환개선효과가우수하고, 비만상태를개선시키며, 당뇨및 고질혈증등의예방, 증상의완화또는치료에효과적이다.
Abstract translation: 本发明涉及含有由低浓度，低等级醇或其馏分提取的豆提取物的组合物。 该组合物在改善血液循环，改善肥胖症和预防糖尿病，高脂血症等方面表现出优异的效果，并且显示减轻或治疗糖尿病，高脂血症等症状的效果。 本发明还涉及一种改善血液循环和血管健康的方法。
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