Abstract:
The present invention relates to a low viscous cosmetic composition using a natural emulsifying agent and, more specifically, to a cosmetic composition which uses natural saccharide surfactants instead of using chemical surfactants and implements a low-viscous formulation whereby it is safe for the skin and provides a feeling of use that the absorption is fast. In addition, the formulation is stable and is effective in enhancing the moisture of the skin.
Abstract:
PURPOSE: A Hibiscus abelmoschus extract and Betula platyphylla var. japonica sap are provided to normalize expression of a gene of which expression is reduced by UV rays, to maintain homeostasis, and to effectively prevent aging. CONSTITUTION: A cosmetic composition for maintaining skin homeostasis contains one or more kinds from a Hibiscus abelmoschus extract and Betula platyphylla var. japonica sap as active ingredients. A cosmetic composition for improving skin elasticity contains one or more kinds from the Hibiscus abelmoschus extract and Betula platyphylla var. japonica sap as active ingredients. A cosmetic composition for antioxidation or antiaging contains one or more kinds from the Hibiscus abelmoschus extract and Betula platyphylla var. japonica sap as active ingredients. [Reference numerals] (AA) Bmal1 expression as compared with 0 hour, %; (BB) Time, h; (CC) UVB 20mJ Betula platyphylla var. japonica sap 50ppm; (DD) UVB 20mJ Hibiscus abelmoschus extract 100ppm
Abstract:
PURPOSE: A measuring method of a skin regeneration effect using a skin equivalent is provided to directly evaluate a skin regeneration effect of a material by performing a wound treatment analysis using a punch biopsy. CONSTITUTION: A dermis layer of a skin regeneration comprises an inside dermis layer and an outside dermis layer. The inside dermis layer comprises a collagen and a fibroblast. The outside dermis layer comprises a collagen. The skin equivalent suppresses a contraction of the dermis. A measuring method of a skin regeneration effect comprises the following steps: a step of making a wound in a epidermis layer of a skin equivalent; a step in which a testing material is processed in a generated wound for 5-10 days; and a step of observing an epimorphic regeneration state of the skin equivalent with time with performing H&E stain(Hematoxylin and Eosin stain) at 2-3 days intervals after processing the testing material. [Reference numerals] (AA) Epidermis layer; (BB) Damaged portion of epidermis; (CC) Dermis layer
Abstract:
PURPOSE: A composition containing a mixture extract of Lycium chinense Miller and Pinus densiflora Siebold et Zuccarini for antiaging through activation of a retinoic acid receptor is provided to ensure excellent skin antiaging or anti-wrinkling. CONSTITUTION: A cosmetic composition for antiaging contains a mixture extract of Lycium chinense Miller and Pinus densiflora Siebold et Zuccarini as an active ingredient. The mixture extract contains 40-60 wt% of the Lycium chinense Miller extract and 40-60 wt% of the Pinus densiflora Siebold et Zuccarini extract. The composition activates a retinoic acid receptor. The composition also prevents wrinkles by suppressing collagenase expression.
Abstract translation:目的:提供含有枸杞子和松果松混合提取物的组合物,用于通过活化视黄酸受体进行抗衰老以确保优异的皮肤抗衰老或抗皱纹。 构成:用于抗衰老的化妆品组合物含有枸杞的混合物提取物和松果松(Siebold et Zuccarini)作为活性成分。 混合物提取物含有40-60重量%的枸杞提取物和40-60重量%的松属松属Siebold和Zuccarini提取物。 该组合物激活视黄酸受体。 该组合物还通过抑制胶原酶表达来防止皱纹。
Abstract:
PURPOSE: A kit and a method for diagnosing seborrheic keratosis are provided to quickly diagnose seborrheic keratosis occurrence using a marker gene. CONSTITUTION: A kit for diagnosing seborrheic keratosis contains polynucleotide containing 10 or more continuous nucleotides or a complementary polynucleotide thereof; and a solid phase support on which a polynucleotide is conjugated on the surface. A kit for diagnosing seborrheic keratosis contains: a polynucleotide containing 18-22 continuous nucleotides as a polynucleotide fragment of WISP2(AK074695); and one or more polynucleotides containing the 18-22 continuous nucleotides, which are a complementary polynucleotide. The kit is used for diagnosing seborrheic keratosis. A method for providing necessary information for diagnosing seborrheic keratosis comprises a step of determining seborrheic keratosis when the expression level of WISP2(AK07495) gene on a subject epidermis is lower than the level on a control group.
Abstract:
PURPOSE: A composition for skin anti-aging is provided to suppress matrix metalloprotease activation without skin irritation. CONSTITUTION: A composition for skin anti-aging contains 0.01-20 weight% of compound of chemical formula 1, isomer or pharmaceutically acceptable salt thereof as an active ingredient. The composition is used for preventing or treating wrinkling and skin aging. The composition is a pharmaceutical composition or cosmetic composition. The pharmaceutical composition is manufactured in the form of lotion, ointment, gel, cream, patch or spray. The cosmetic composition is used in the form of essence, nutrition cream, massage cream, pack, gel, essence, eye cream, cleansing cream, cleansing foam, pack, and powder.