Abstract:
본 발명은 피부 항상성 유지에 도움을 주는 화장료 조성물에 관한 것으로, 보다 상세하게는 자작나무 추출물을 함유하여 자외선에 의해 발현이 감소된 유전자의 발현을 정상화시킴으로써 피부세포의 항상성 유지 효과를 가지는 화장료 조성물에 관한 것이다. 자작나무, Clock, bmal1/mop3, 피부 온도, 피부 혈류량, 피부 수분량, 피부 항상성
Abstract:
Cosmetic compositions containing the extract of white birch are provided to normalize reduction of skin gene expression caused by ultraviolet rays without side effects, thereby maintaining skin homeostasis. A cosmetic composition for maintaining skin homeostasis comprises 0.001-30 wt.% of the white birch extract which normalizes the expressions of Clock or bmal1/mop3 genes reduced by ultraviolet rays, and are prepared by pulverizing white birch, dipping pulverized white birch in a solvent selected from purified water, methanol, ethanol, propanol, butanol, glycerol, propyleneglycol, 1,3-butyleneglycol, methylacetate, ethylacetate, benzene, hexane, diethylether and dichloromethane for 5 days, and filtering, concentrating and freeze-drying the extract. The composition is formulated as cleanser, oil, lotion, soft lotion, nutrition lotion, nutrition cream, massage cream, pack, gel or essence.