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公开(公告)号：KR101654977B1
公开(公告)日：2016-09-07
申请号：KR1020140091212
申请日：2014-07-18
Applicant: 연세대학교 산학협력단
IPC: A61K36/28 , A61K31/045 , A61P3/04 , A61P3/00
Abstract: 본발명은키레놀(kirenol) 또는이를함유하는시게스벡키아오리엔탈리스(Siegesbeckia orientalis L.) 추출물을유효성분으로포함하는비만예방, 개선또는치료용조성물에관한것이다. 본발명에따른키레놀(kirenol), 또는이를함유하는시게스벡키아오리엔탈리스추출물또는이의분획물은지방세포내에서지방세포분화에관여하는주요전사인자(PPARγ, C/EBPα, 및 SREBP-1c)의발현을감소시킴에따라, 비만에우수한효과가있다. 또한, 본발명은천연물이므로부작용없이안전하게사용될수 있어, 의약품또는식품으로사용될수 있다.
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22.发明公开
公开(公告)号：KR1020150145332A
公开(公告)日：2015-12-30
申请号：KR1020140074397
申请日：2014-06-18
Applicant: 연세대학교 산학협력단
IPC: A61K36/9068 , A61K31/122 , A61P1/02 , A61P1/00
CPC classification number: A61K36/9068 , A61K31/122
Abstract: 본발명은캠페리아파비플로라 () 추출물또는이의분획물을유효성분으로포함하는치주질환의예방, 개선또는치료용조성물, 및하기화학식 1 내지 3으로표시되는화합물로이루어진군으로부터선택된하나이상의플라본계화합물또는이의약학적으로허용가능한염을유효성분으로포함하는치주질환의예방, 개선또는치료용조성물에관한것으로, 이들유효성분은교원질분해효소및 골흡수효소의생성을억제하여치주질환및 구강관리에매우유용하게사용될수 있다: [화학식 1], [화학식 2], 및 [화학식 3].
Abstract translation: 本发明涉及一种用于预防，减轻或治疗牙龈炎的组合物，其中含有山奈酚提取物或其部分作为活性成分，以及用于预防，减轻或治疗牙周炎的组合物，所述组合物含有至少一种选自化合物 表示为化学式1〜3或其药学上可接受的盐作为活性成分。 通过抑制胶原降解酶和骨吸收酶的产生，活性成分可以有效地用于治疗口腔和牙周病。
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公开(公告)号：KR1020150113687A
公开(公告)日：2015-10-08
申请号：KR1020140038037
申请日：2014-03-31
Applicant: 연세대학교 산학협력단 , 주식회사 제이솔
IPC: A23L1/30 , A61K36/8962 , A61P19/10
CPC classification number: A23L19/00 , A23V2002/00 , A23V2200/306 , A61K36/8962
Abstract: 본발명은삼채() 추출물을유효성분으로포함하는골다공증예방및 치료/개선용조성물에관한것으로, 보다상세하게는삼채추출물을유효성분으로포함하는골다공증예방및 치료/개선용조성물에관한것이다. 본발명의삼채추출물은조골세포분화조절유전자(ALP 및 ColA1)의발현을증가시킴으로서골다공증에우수한예방및 치료효과를보인다. 따라서천연물이므로부작용없이안전하게사용될수 있으며, 조골세포분화유전자를조절하여골다공증예방및 치료/개선에탁월한효과를보이는조성물을제공한다.
Abstract translation: 本发明涉及一种用于预防和治疗/减轻骨质疏松症的组合物，其含有作为活性成分的hook i提取物。 本发明的葱属提取物增加了成骨细胞分化调节基因（ALP和ColA1）的表达，表现出优异的预防和治疗骨质疏松症的作用。 因此，组合物是天然材料，因此安全地使用而没有副作用。 调整成骨细胞分化基因，因此组合物表现出优异的预防和治疗/缓解骨质疏松症的作用。
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公开(公告)号：KR101476761B1
公开(公告)日：2014-12-29
申请号：KR1020110052191
申请日：2011-05-31
Applicant: 씨제이제일제당 (주) , 연세대학교 산학협력단
Abstract: 본발명은지방세포의 UCP 활성으로인한발열작용으로항비만에효과적인식품및 약제조성물에관한것으로, 구체적으로는파이퍼레트로프락텀(Vahl)의추출물을함유하는조성물의신규용도에관한것으로, 체중및 체지방감소를통한항비만에효과적인식품조성물또는약제학적조성물에관한것이다.
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公开(公告)号：KR1020130136053A
公开(公告)日：2013-12-12
申请号：KR1020120059581
申请日：2012-06-04
Applicant: 연세대학교 산학협력단
IPC: A61K31/56 , A61K31/575 , A61P3/04 , A61P3/00
CPC classification number: A61K31/575 , Y10S514/909
Abstract: The present invention relates to a use of fucosterol, more specifically an anti-obesity composition comprising fucosterol. The fucosterol improves the lipogenesis control and heating activity for providing an excellent effect in anti-obesity. [Reference numerals] (AA) Fucosterol (쨉M)
Abstract translation: 本发明涉及岩藻甾醇的用途，更具体地说，涉及包含岩藻甾醇的抗肥胖组合物。 岩藻甾醇改善了脂肪生成控制和加热活性，为抗肥胖提供了极好的效果。 （AA）福斯特醇（쨉M）
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Patent Agency Ranking26.发明公开캠페리아 파비플로라 추출물 또는 플라본계 화합물을 함유하는 근육 질환 예방 및 치료용 또는 근 기능 개선용 조성물 有权用于预防和治疗肌肉疾病的组合物或改善包含加利福尼亚芽孢杆菌提取物或FLAVONE化合物的音乐功能
公开(公告)号：KR1020130128349A
公开(公告)日：2013-11-26
申请号：KR1020130056024
申请日：2013-05-16
Applicant: 연세대학교 산학협력단
IPC: A61K36/9068 , A61K31/352 , A61P21/00
CPC classification number: A61K36/906 , A61K31/35 , A61K31/352
Abstract: The present invention relates to a pharmaceutical composition containing Kaempferia parviflora Wall. extract or flavone-based compound for muscular diseases treatment and, more specifically, a pharmaceutical composition containing the Kaempferia parviflora Wall. extract or flavone-based compound which is dissociated therefrom and presented by the chemical formula 4, as an active ingredient, for muscular diseases treatment and a food composition for improving muscular functions and exercise performance ability. The Kaempferia parviflora Wall. extract and flavone-based compound dissociated therefrom are effective in manufacturing the pharmaceutical composition for muscular diseases treatment or the food composition for improving muscular functions since the components decrease protein catabolism of muscles and increase muscle cell differentiation and anabolism. [Reference numerals] (AA) 5,7-dimethoxyflavone (쨉M)
Abstract translation: 本发明涉及含有山茱萸叶的药物组合物。 用于肌肉疾病治疗的提取物或基于黄酮的化合物，更具体地说，是含有山莨菪碱壁的药物组合物。 提取物或黄酮类化合物，其由化学式4分解并作为活性成分提供用于肌肉疾病治疗和用于改善肌肉功能和运动性能的食物组合物。 Kaempferia parviflora墙。 从其分解的提取物和基于黄酮的化合物在制备用于肌肉疾病治疗的药物组合物或用于改善肌肉功能的食物组合物中是有效的，因为该成分降低肌肉的蛋白质分解代谢并增加肌肉细胞分化和合成代谢。 （AA）5,7-二甲氧基黄酮（쨉M）
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公开(公告)号：KR1020110119482A
公开(公告)日：2011-11-02
申请号：KR1020100039225
申请日：2010-04-27
Applicant: (주)뉴트리 , 연세대학교 산학협력단
IPC: A61K31/357 , A61K36/185 , A23L1/30 , A61K8/97
CPC classification number: A61K31/357 , A23L33/105 , A23V2200/304 , A23V2200/324 , A61K8/97 , A61K36/185
Abstract: PURPOSE: A composition containing macelignan, nutmeg extract, or salt thereof for preventing and treating allergic diseases is provided to relieve excessive immune response. CONSTITUTION: A pharmaceutical composition for preventing and treating allergic diseases contains macelignan or pharmaceutically acceptable salt thereof as an active ingredient. A food compoisiton for preventing and relieving allergic diseases contains macelignan or salt thereof as an active ingredient. A cosmetic composition for preventing and treating allergic diseases contains macelignan or salt thereof as an active ingredient. A pharmaceutical composition for preventing and treating allergic diseases contains nutmeg extract as an active ingredient.
Abstract translation: 目的：提供含有肉豆蔻衣木脂素，肉豆蔻提取物或其盐的组合物，用于预防和治疗过敏性疾病以减轻过度的免疫应答。 构成：用于预防和治疗过敏性疾病的药物组合物含有肉豆蔻衣木素或其药学上可接受的盐作为活性成分。 用于预防和缓解过敏性疾病的食物副产物含有肉豆蔻衣木脂素或其盐作为活性成分。 用于预防和治疗过敏性疾病的化妆品组合物含有肉豆蔻衣木脂素或其盐作为活性成分。 用于预防和治疗过敏性疾病的药物组合物含有肉豆蔻提取物作为活性成分。
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公开(公告)号：KR1020080018855A
公开(公告)日：2008-02-28
申请号：KR1020070086169
申请日：2007-08-27
Applicant: 연세대학교 산학협력단 , (주)에스.앤.디
IPC: A61K31/05 , A61K31/047 , A61K31/04 , A61P31/04
CPC classification number: A61K31/122
Abstract: A Panduratin A isolated from the extract of Kaempferia pandurata or its derivative is provided to inhibit growth of bacteria including acne-causing bacteria in the skin without side effects, so that it is useful for treatment of acnes effectively. An antibacterial composition comprises a Panduratin A compound isolated from the extract of Kaempferia pandurata, represented by the formula(1) or the formula(2), or its derivative, and inhibits growth of Propionibacterium acnes, Staphylococcus epidermis, Micrococcus luteus, Staphylococcus aureus, Staphylococcus warneri, Staphylococcus haemolyticus, Staphylococcus xylosus, Staphylococcus hominis and Staphylococcus saprophyticus, wherein the extract of Kaempferia pandurata is prepared by extracting Kaempferia pandurata with water or a C1-C6 organic solvent selected from alcohol, acetone, ether, benzene, chloroform, ethyl acetate, methylene chloride, hexane, cyclohexane and petroleum ether.
Abstract translation: 提供从山羊皮或其衍生物提取物中分离出的潘多汀A，以抑制细菌生长，包括皮肤中的痤疮细菌，无副作用，有效治疗痤疮。 抗菌组合物包含从由式（1）或式（2）表示的山羊皮提取物或其衍生物中分离出的潘多汀A化合物，抑制痤疮丙酸杆菌，表皮葡萄球菌，藤黄微球菌，金黄色葡萄球菌， 葡萄球菌，溶血葡萄球菌，葡萄球菌，腐生葡萄球菌和腐生葡萄球菌，其中通过用水或选自醇，丙酮，乙醚，苯，氯仿，乙酸乙酯的C1-C6有机溶剂萃取山楂提取物， ，二氯甲烷，己烷，环己烷和石油醚。
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公开(公告)号：KR100756669B1
公开(公告)日：2007-09-10
申请号：KR1020060010166
申请日：2006-02-02
Applicant: 이화여자대학교 산학협력단 , 연세대학교 산학협력단
Abstract: 본 발명은 복숭아 나무 (
Prunus
persica (L.) BATSCH)의 과실, 즉 도자 (
Persicae
fructus )의 구성 중 도인 (amygdalin)을 제외한 과피 및 과육 추출물을 유효성분으로 함유하는 조성물에 관한 것으로, 구체적으로 본 발명의 도자 추출물은 시험관 내 (
in vitro ) 실험에서 우수한 티로시나제 저해활성을 나타내며 생체 내 (
in
vivo ) 실험에서 멜라닌 합성 저해 활성을 나타내는 바 피부 미백용 화장료 조성물로 유용하게 이용될 수 있다.
도자, 미백, 티로시나제, 멜라닌, 화장료 조성물-
公开(公告)号：KR1020070079467A
公开(公告)日：2007-08-07
申请号：KR1020060010166
申请日：2006-02-02
Applicant: 이화여자대학교 산학협력단 , 연세대학교 산학협력단
Abstract: A cosmetic composition with whitening activity is provided to have excellent tyrosinase inhibition activity and excellent melanogenesis inhibition activity by comprising an extract of Persicae fructus. The cosmetic composition comprises 0.001-90 wt.% of an extract of Persicae fructus which is prepared from pericarp and flesh of the Persicae fructus except amygdalin by using at least one solvent selected from the group consisting of water, C1-4 alcohol, propylene glycol, ethyl acetate, butylene glycol, ether, and chloroform.
Abstract translation: 提供具有增白活性的化妆品组合物，其具有优异的酪氨酸酶抑制活性和优异的黑素生成抑制活性，其包括芍药提取物。 化妆品组合物包含0.001-90重量％的柿子提取物，其通过使用选自水，C 1-4醇，丙二醇中的至少一种溶剂制备，除了杏仁核以外，由柿果皮和肉制成 ，乙酸乙酯，丁二醇，乙醚和氯仿。
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