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公开(公告)号：KR1020130114877A
公开(公告)日：2013-10-21
申请号：KR1020120037273
申请日：2012-04-10
Applicant: (주)아모레퍼시픽
IPC: C07D493/04 , A61K31/34 , A61P35/00
CPC classification number: C07D493/04
Abstract: PURPOSE: A method for manufacturing a furofuran lignan compound is provided to selectively manufacture (+)-furofuran lignan and (-)-furofuran lignan, which is an optical isomer thereof. CONSTITUTION: A method for manufacturing a furofuran lignan compound comprises the step of O-alkylating one selected from a compound in Chemical Formula 1 and an optical isomer thereof. The furofuran lignan compound comprises a compound in Chemical Formula 7 or 8. The optical isomer of the compound in Chemical Formula 1 is manufactured by a reaction of a compound in Chemical Formula 11 and (+)-diisopropyltryptamine (DIPT) or (-)-DIPT.
Abstract translation: 目的：提供呋喃呋喃木酚素化合物的制备方法，以选择性地制备（+） - 呋喃呋喃木酚素和（ - ） - 呋喃呋喃木酚素，其为其光学异构体。 构成：制备呋喃呋喃木酚素化合物的方法包括将选自化学式1中的化合物和其旋光异构体中的一种O-烷基化的步骤。 呋喃呋喃木酚素化合物包含化学式7或8中的化合物。化学式1中化合物的光学异构体是通过化学式11中的化合物和（+） - 二异丙基色胺（DIPT）或（ - ） - DIPT。
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公开(公告)号：KR1020130045631A
公开(公告)日：2013-05-06
申请号：KR1020110109961
申请日：2011-10-26
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A composition containing syringaresinol for treating immune diseases is provided to promote SIRT 1 expression in immunocytes and differentiation to type 2 immunocytes, and to prevent or treat immune diseases. CONSTITUTION: A composition for preventing or treating immune diseases contains 1-80 wt% of syringaresinol as an active ingredient. The immune diseases include one or more among allergy, atopic dermatitis, hay fever, and rheumatoid arthritis. Syringaresinol is contained in one or more extracts selected among a linseed extract, a Phellodendri cortex extract, a sesame extract, and a ginseng fruit extract. [Reference numerals] (AA) MRNA of SIRT1 compared to a control group; (BB) 20uM syringaresinol; (CC) 50uM syringaresinol; (DD) 100uM syringaresinol
Abstract translation: 目的：提供一种含有用于治疗免疫疾病的丁香麻醇的组合物，用于促进免疫细胞中的SIRT1表达，分化为2型免疫细胞，并预防或治疗免疫疾病。 构成：用于预防或治疗免疫疾病的组合物含有1-80重量％的作为活性成分的丁香麻醇。 免疫疾病包括过敏，特应性皮炎，花粉症和类风湿性关节炎中的一种或多种。 苯丁酸钠含有选自亚麻子提取物，黄柏提取物，芝麻提取物和人参果实提取物中的一种或多种提取物。 [参考数字] SIRT1与对照组相比的（AA）MRNA; （BB）20uM syringaresinol; （CC）50uM syringaresinol; （DD）100uM syringaresinol
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公开(公告)号：KR101918143B1
公开(公告)日：2018-11-15
申请号：KR1020120037273
申请日：2012-04-10
Applicant: (주)아모레퍼시픽
IPC: C07D493/04 , A61K31/34 , A61P35/00
CPC classification number: C07D493/04
Abstract: 본발명은에폭시알코올화합물및 그광학이성질체를선택하여알킬화하는단계를포함하는푸로푸란리그난화합물의제조방법을개시한다. 상기방법은 (+)-푸로푸란리그난과그의광학이성질체인 (-)-푸로푸란리그난을선택적으로제조할수 있게한다.
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公开(公告)号：KR101433539B1
公开(公告)日：2014-08-27
申请号：KR1020130134953
申请日：2013-11-07
Applicant: (주)아모레퍼시픽
IPC: A61K36/484 , A61K36/48 , A61P25/00 , A61P19/00
CPC classification number: A61K31/35 , A23L2/52 , A23L33/10 , A23L33/105 , A23L33/15 , A23P10/28 , A23P10/30 , A61K9/0095 , A61K31/37 , A61K36/48
Abstract: 본 발명은 쿠메스트롤 또는 쿠메스트롤을 포함하는 콩 추출물을 유효 성분으로 포함하는 미토콘드리아 활성화용 조성물을 개시한다.
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公开(公告)号：KR1020130108853A
公开(公告)日：2013-10-07
申请号：KR1020120030643
申请日：2012-03-26
Applicant: (주)아모레퍼시픽
CPC classification number: A61K36/82 , A23L33/105 , A23V2200/326 , A23V2200/328 , A23V2200/332 , A61K2236/33 , Y10S514/824 , Y10S514/866 , Y10S514/909
Abstract: PURPOSE: A composition containing triterpenoid saponin extracted from a methanol extract of Camellia sinensis roots is provided to effectively prevent or treat diabetes, obesity, and hypertension and to be used in food and medical fields. CONSTITUTION: A composition for preventing and treating diabetes contains 0.01-20 wt% of triterpenoid saponin extracted from a methanol extract of Camellia sinensis roots as an active ingredient. Triterpenoid saponin is denoted by chemical formulas 1-10. The composition is a pharmaceutical composition and a health food composition. [Reference numerals] (AA) Green tea ponin R1; (BB) Green tea ponin R2; (CC) Green tea ponin R3; (DD) Green tea ponin R4; (EE) Green tea ponin R5; (FF) Green tea ponin R6; (GG) Green tea ponin R7; (HH) Green tea ponin R8; (II) Green tea ponin R9; (JJ) Green tea ponin R10
Abstract translation: 目的：提供从山茶根的甲醇提取物中提取的三萜皂苷的组合物，以有效预防或治疗糖尿病，肥胖和高血压，并用于食品和医疗领域。 构成：用于预防和治疗糖尿病的组合物含有0.01-20重量％的从山茶根的甲醇提取物中提取的三萜皂苷作为活性成分。 三萜皂苷由化学式1-10表示。 组合物是药物组合物和保健食品组合物。 [参考数字]（AA）绿茶叶素R1; （BB）绿茶茶素R2; （CC）绿茶茶素R3; （DD）绿茶茶素R4; （EE）绿茶色素R5; （FF）绿茶叶素R6; （GG）绿茶叶素R7; （HH）绿茶ponin R8; （二）绿茶色素R9; （JJ）绿茶叶素R10
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Patent Agency Ranking
公开(公告)号：KR1020130103882A
公开(公告)日：2013-09-25
申请号：KR1020120024869
申请日：2012-03-12
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: An antiobesity agent containing a hot water extract of Piper longum L. is provided to promote lipolysis of subcutaneous adipocytes and to suppress fat accumulation in the subcutaneous adipocytes, thereby preventing or suppressing obesity. CONSTITUTION: An antiobesity agent contains 1-80 wt% of a hot water extract of Piper longum L. as an active ingredient. The extract promotes the decomposition of subcutaneous fat. The obesity is caused by lipid intake. The hot water used for preparing the extract is water of 80-120°C. [Reference numerals] (AA) Degree of fat breakdown (comparing to negative control group); (BB) Hot water 10; (CC) Hot water 50; (DD) Hot water 100; (EE) Alcohol 10; (FF) Alcohol 50; (GG) Alcohol 100
Abstract translation: 目的：提供含有琵琶龙肝的热水提取物的抗肥胖剂，以促进皮下脂肪细胞的脂肪分解，并抑制皮下脂肪细胞中的脂肪蓄积，从而预防或抑制肥胖。 构成：抗肥胖剂含有1-80重量％的琵琶龙虾热水提取物作为活性成分。 提取物促进皮下脂肪的分解。 肥胖是由脂质摄入引起的。 用于制备提取物的热水为80-120℃的水。 （AA）脂肪分解程度（与阴性对照组相比）; （BB）热水10; （CC）热水50; （DD）热水100; （EE）醇10; （FF）酒精50; （GG）酒精100
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公开(公告)号：KR1020130044707A
公开(公告)日：2013-05-03
申请号：KR1020110108904
申请日：2011-10-24
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A composition containing syringaresinol is provided to suppress fatty acid synthesis, to promote fatty acid oxidation, to enhance PGC 1 expression, and to prevent and treat obesity and hyperlipidemia. CONSTITUTION: A composition for preventing or treating dysbolism contains 1-80 wt% of syringaresinol as an active ingredient. Dysbolism includes disorders of carbohydrate metabolism or lipid metabolism, selected from the group consisting of obesity, type 2 diabetes, hyperlipidemia, and fatty liver. Syringaresinol is contained in extracts which is prepared using one or more selected among linseed, Phellodendron amurense Ruprecht, Acanthopanax senticosus, sesame seeds, and ginseng fruits. [Reference numerals] (AA) mRNA expression of relative SIRT 1; (BB) Fat cell; (CC) Liver cell; (DD) Muscle cell
Abstract translation: 目的：提供含有丁香胺的组合物，以抑制脂肪酸合成，促进脂肪酸氧化，增强PGC 1表达，并预防和治疗肥胖和高脂血症。 构成：用于预防或治疗dysbolism的组合物含有1-80重量％的作为活性成分的丁香胺。 嗜睡症包括选自肥胖症，2型糖尿病，高脂血症和脂肪肝的碳水化合物代谢或脂质代谢紊乱。 提取物中含有辛伐他汀，该提取物使用亚麻籽，黄柏，麻黄，芝麻，人参果实中的一种或多种进行制备。 （AA）相对于SIRT1的mRNA表达; （BB）脂肪细胞; （CC）肝细胞; （DD）肌肉细胞
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公开(公告)号：KR1020110110053A
公开(公告)日：2011-10-06
申请号：KR1020110029585
申请日：2011-03-31
Applicant: (주)아모레퍼시픽
IPC: A61K36/484 , A61K36/48 , A61P25/00 , A61P19/00
CPC classification number: A61K31/35 , A23L2/52 , A23L33/10 , A23L33/105 , A23L33/15 , A23P10/28 , A23P10/30 , A61K9/0095 , A61K31/37 , A61K36/48
Abstract: 본 발명은 쿠메스트롤 또는 쿠메스트롤을 포함하는 콩 추출물을 유효 성분으로 포함하는 미토콘드리아 활성화용 조성물을 개시한다.
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公开(公告)号：KR101886350B1
公开(公告)日：2018-09-11
申请号：KR1020120030643
申请日：2012-03-26
Applicant: (주)아모레퍼시픽
IPC: A61K36/82 , A23L33/105
Abstract: 본발명은차나무뿌리에서추출한트리테르페노이드사포닌을함유하는조성물에관한것으로서, 보다상세하게는차나무뿌리의메탄올추출물에서분리한트리테르페노이드사포닌을함유함으로써당뇨, 비만, 고혈압등의치료또는예방효과를제공할수 있어식품및 의약분야에서다양하게활용가능한건식조성물에관한것이다.
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公开(公告)号：KR1020150110378A
公开(公告)日：2015-10-02
申请号：KR1020150038323
申请日：2015-03-19
Applicant: (주)아모레퍼시픽
Abstract: 본명세서는후발효차추출물을유효성분으로포함하는조성물을제공한다. 본명세서에따른조성물은비만, 염증, 또는당뇨의치료, 개선또는예방용조성물일 수있으며, 구체적으로이러한조성물은약학조성물또는식품조성물일수 있다. 본명세서에따른조성물은지방세포분화억제또는중성지방축적억제효과를가지므로비만치료에관한분야에서유용하게사용될수 있다. 또한본 명세서에따른조성물은장내의간균의비율을조절하는효과를나타내며, 이에따라체질개선에효과를나타낼수 있다.
Abstract translation: 提供了包含发酵后茶提取物作为活性成分的组合物。 根据本说明书的组合物可以是用于治疗，减轻或预防肥胖，炎症或糖尿病的组合物。 更具体地，组合物可以是药物组合物或食物组合物。 根据本说明书的组合物具有抑制脂肪细胞分化或抑制甘油三酯积聚的效果，因此有利地用于与肥胖症治疗有关的领域。 此外，根据本说明书的组合物可以显示调节肠杆菌的比例的效果，因此显示出改善体质的效果。
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