公开(公告)号：KR101473644B1

公开(公告)日：2014-12-18

申请号：KR1020120113128

申请日：2012-10-11

Applicant: 강원대학교산학협력단

Inventor： 우흥명 ,  양세란 ,  박성민

IPC: C12N5/077 ,  C12N5/16 ,  A61K35/32

Abstract: 본발명은 Bglap(bone gamma carboxyglutamte protein) 유전자를이용한지방유래중간엽줄기세포를골아세포로분화시키는방법에관한것이다.본발명에따른지방에서채취한줄기세포를골세포로분화시키는방법에관한본 발명은종래골수로부터채취한줄기세포를골세포로분화시키는방법에따른문제들을해결할수 있어, 이를이용하여골조직의재생이필요한다양한질환에응용이가능하다.

公开(公告)号：KR1020140046858A

公开(公告)日：2014-04-21

申请号：KR1020120113037

申请日：2012-10-11

Applicant: 강원대학교산학협력단

Inventor： 우흥명 ,  박성민 ,  안철

IPC: A61D1/00 ,  A61F2/10 ,  A61B17/322 ,  A61D7/00

CPC classification number: A61D1/00 ,  A61B17/322 ,  A61D7/00 ,  A61F2/105

Abstract: The present invention relate to a skin transplantation method for facilitating a collection of skin tissue comprising transplants when transplanting an animal skin. When using the skin transplantation method according to the present invention, a graft is firmly fixed to an implant site whereby risk of loss is small; and abundant samples can be acquired from a small number of animals, thereby enabling an effective application in research of transplant rejection in animals, etc.

Abstract translation: 本发明涉及一种皮肤移植方法，用于在移植动物皮肤时促进包含移植物的皮肤组织的收集。 当使用根据本发明的皮肤移植方法时，移植物牢固地固定到植入部位，由此损失的风险小; 可以从少量动物获得丰富的样品，从而有效应用于动物等中的移植排斥研究。

公开(公告)号：KR1020130086734A

公开(公告)日：2013-08-05

申请号：KR1020120007634

申请日：2012-01-26

Applicant: 강원대학교산학협력단

Inventor： 우흥명 ,  박성민 ,  안철 ,  박경미

IPC: A61L27/56 ,  A61L27/38

CPC classification number: A61L27/56 ,  A61L27/38 ,  A61L2430/28 ,  A61L2430/40

Abstract: PURPOSE: A method for removing heterologous immunogens and retrovirus from a bioscaffold is provided to prevent acute immune rejection or infection of retrovirus. CONSTITUTION: A method for removing heterologous immunogens and retrovirus from a bioscaffold comprises the following steps: preparing an internal organ to make a bioscaffold; and dipping the internal organ in a surfactant. The internal organ is the liver of a pig. The surfactant is 0.1-0.25% concentration of sodium dodecyl sulfate.

Abstract translation: 目的：提供从生物支架中去除异源免疫原和逆转录病毒的方法，以防止急性免疫排斥反应或感染逆转录病毒。 构成：从生物支架中除去异源免疫原和逆转录病毒的方法包括以下步骤：制备内部器官以制备生物支架; 并将内部器官浸入表面活性剂中。 内脏是猪的肝脏。 表面活性剂的浓度为0.1-0.25％十二烷基硫酸钠。

公开(公告)号：KR1020130007489A

公开(公告)日：2013-01-18

申请号：KR1020120113087

申请日：2012-10-11

Applicant: 강원대학교산학협력단

Inventor： 우흥명 ,  박성민 ,  박경미 ,  안철

IPC: A61L27/56 ,  A61L27/38 ,  A61F2/02

CPC classification number: A61L27/56 ,  A61F2/02 ,  A61L27/38

Abstract: PURPOSE: A manufacturing method of bio scaffold is provided to remove major heteroimmunity antigen and manhole cask virus pathogen. CONSTITUTION: A manufacturing method of bio scaffold comprises the following steps: preparing an organ which will be manufactured into bio scaffold; and dipping the organ into SDS (sodium dodecyl sulfate). The organ is selected from a group consisting of anthropoid, pig, cow, sheep, and goat. When the organ is belong to pig, liver is used. The concentration of the SDS is 0.05-0.25 %.

Abstract translation: 目的：提供生物支架的制造方法，以去除主要的异种免疫抗原和人孔病毒病毒病原体。 构成：生物支架的制造方法包括以下步骤：制备将制成生物支架的器官; 并将器官浸入SDS（十二烷基硫酸钠）中。 器官选自人类，猪，牛，绵羊和山羊。 当器官属于猪时，使用肝脏。 SDS的浓度为0.05-0.25％。