-
公开(公告)号：KR101576992B1
公开(公告)日：2015-12-14
申请号：KR1020130138333
申请日：2013-11-14
Applicant: 대한민국(농촌진흥청장)
Abstract: 본발명은개의꼬리뼈형질진단을유전자마커및 이를이용한진단방법에관한것이다. 본발명에따른표지인자를활용하면표현형가에의한선발효과에비해더 정확한유전능측정이가능하며, 개의꼬리뼈형질을조기에예측할수 있다. 또한, 반려견의꼬리모양에대한애견가들의선호도를충족시킬수 있고, 개의꼬리가없는무미나단미의개를생산하기위해무분별한번식을제한할수 있음으로써반려견의보호복지정책에일조함으로서반려견문화정착이가능하며, 개의꼬리의형성에관련된유전자를발굴함으로서동물의진화에대한학술적가치와뼈의재생과관련된의학적기초정보를확보할수 있다.
-
公开(公告)号：KR101353083B1
公开(公告)日：2014-01-17
申请号：KR1020110145794
申请日：2011-12-29
Applicant: 대한민국(농촌진흥청장)
Abstract: 본 발명은 돼지의 다산 개체 선발을 위한 SNP 마커와 이를 이용한 방법으로서, 보다 상세하게는, 돼지의 산자수와 연관관계를 나타내는 SNP 마커, 마이크로어레이, 키트 및 이를 이용한 선별방법에 관한 것이다. 본 발명의 SNP는 돼지의 중요 유전자에 위치하여 많은 경제 형질들과 관련이 있을 것으로 판단된다. 특히 이 SNP들은 엑손부위에서의 변이로서 단백질의 변이를 유발하므로 돼지에게 큰 영향을 미칠 것이라 예상된다. 본 발명에서 제공하는 SNP들은 산자수와 높은 연관성을 나타내고 있으므로, 종돈의 조기선발에 활용할 가치가 대단히 높다.
-
公开(公告)号：KR101316709B1
公开(公告)日：2013-10-15
申请号：KR1020100134804
申请日：2010-12-24
Applicant: 대한민국(농촌진흥청장)
Abstract: 본 발명은 돼지의 일당증체량 확인을 위한 단일염기다형성(SNP) 표지 인자, 이를 이용한 돼지의 일당증체량 확인을 위한 키트, 돼지의 일당증체량에 관한 정보를 제공하는 방법 및 종돈의 선발 방법에 관한 것으로, 본 발명에 따르면, 돼지의 성장과 관련된 원인유전자 검출 및 육종가 추정을 통한 돼지 종돈 선발이 매우 유용하고, 선발의 정확성을 제고할 수 있어 유전능력 개량을 극대화 할 수 있다. 또한 표현형평가에 의한 종래의 선발 방법보다 25~35% 더 정확한 유전능력 측정이 가능하여 종돈의 유전능력 개량량을 획기적으로 늘릴 수 있으며, 일당증체량은 현재 돼지의 성장 정도를 평가하는 중요한 기준으로 활용되고 있으므로 우수 종돈의 국내 육성에 크게 기여할 수 있다.
-
公开(公告)号：KR1020130077207A
公开(公告)日：2013-07-09
申请号：KR1020110145794
申请日：2011-12-29
Applicant: 대한민국(농촌진흥청장)
CPC classification number: C12Q1/6888 , C12Q2600/124 , C12Q2600/156
Abstract: PURPOSE: A SNP marker for polyacid entity selection of pig and an evaluation method using the same are provided to have high value on use at pre-selection of breeding pig by expressing high connection with a litter size, and to be predectied to have a big influence on the pig with SNP by generating protein variation on the exon region. CONSTITUTION: A pig polyacid entity selection method uses any selected one group a group comprised with SNP of sequence number of 1 through 54. A discriminating method of the pid polyacid entity is i) an extracting step of DNA from a subject; ii) an amplifying step of DNA including the base part of the sequcne number of 1 through 54 or the complemental strand of the base pair at the base mutation; iii) a determining step of the base mutation on the base sequence. The SNP set comprises the complex of any SNP comprised with the sequence number 1 through 54 for determining the pig polyacid entity. The primer set for the pig polyacid entity selection comprises an oligonucleotide including a base region of the sequence number 1 through 54 or the base region of the base mutation comprising the complementary strand with the base pair, or the base region with the sequence number 1 through 54 or the oligonucleotide having the base sequence of non-continuouse sequence of base 1 adjacent to the base mutation comoprising the complementary strand with the base pair.
Abstract translation: 目的：提供猪多聚体实体选择的SNP标记和使用其的评价方法，通过表达高度连带的仔猪大小，预先选择繁殖猪具有较高的价值，并被预测为具有较大的 通过在外显子区域产生蛋白质变异对SNP的猪产生影响。 构成：猪多酸实体选择方法使用任意选择的一个组，序列号为1至54的SNP组成的组。多肽实体的鉴别方法是i）来自受试者的DNA的提取步骤。 ii）在碱基突变时，包含1至54的序列的碱基部分或碱基对的互补链的DNA的扩增步骤; iii）碱基序列上的碱基突变的确定步骤。 SNP组包含用于确定猪多元酸实体的序列号1至54所包含的任何SNP的复合物。 猪多酸实体选择的引物组包括包含序列号1至54的碱基区域的碱基区域或包含与碱基对的互补链的碱基突变的碱基区域或序列号1至 54或与碱基突变相邻的碱基1的非连续序列的碱基序列与碱基对互补的寡核苷酸。
-
公开(公告)号：KR1020130077198A
公开(公告)日：2013-07-09
申请号：KR1020110145779
申请日：2011-12-29
Applicant: 대한민국(농촌진흥청장)
CPC classification number: C12Q1/6888 , C12Q2600/124 , C12Q2600/156
Abstract: PURPOSE: A single nucleotide polymorphism genetic marker for an object identification and a history management of pic, and a diagnostic method are provided to increase reliability of analysis by being capable of having concurrent genetic analyzing method and functional object identification tool of RFID, using a genetic analyzing method for a pork history management, and even more accurate heredity measurement than selection effect by phenotypic value. CONSTITUTION: An object identification method of a pig comprises a verification of a single nucleotide polymorphism which is 61st nucleotice sequence of polynucleotide selected among the sequence number 1 thorugh 38. The step of verifying the single nucleotide polymorphism is performed by selected group comprised of allelespecific probe hybridization, allele-specific amplification, sequencing, 5' nuclease digestion, molecular beacon assay, oligonucleotide ligation assay, size analysis, and single-stranded conformation polymorphism. A microarray for the single nucleotide polymorphism detection comprises the polynucleotide for detecting base sequence of the single nucleotide polymorphism, and and the polypeptde encoded thereby or the cDNA of the polynucleotide. A kit for detecting the single nucleotide polymorphism comprises the polynucleotide for detecting the base sequence of the single nucleotide polymorphism, and the polypeptde encoded thereby or the cDNA of the polynucleotide.
Abstract translation: 目的：提供一种用于对象识别和pic历史管理的单核苷酸多态性遗传标记，并提供诊断方法，通过能够使用遗传分析的并行遗传分析方法和功能对象识别工具提高分析的可靠性，使用遗传 猪肉历史管理的分析方法，甚至比表型价值的选择效果更准确的遗传度测量。 构成：猪的物体识别方法包括核苷酸序列号1第36号中选择的多核苷酸的第61位核苷酸序列的单核苷酸多态性。核苷酸多态性的检验步骤由选自由等位基因特异性探针 杂交，等位基因特异性扩增，测序，5'核酸酶消化，分子信标测定，寡核苷酸连接测定，大小分析和单链构象多态性。 用于单核苷酸多态性检测的微阵列包括用于检测单核苷酸多态性的碱基序列的多核苷酸，以及由其编码的多肽或多核苷酸的cDNA。 用于检测单核苷酸多态性的试剂盒包含用于检测单核苷酸多态性的碱基序列的多核苷酸，以及由此编码的多肽或多核苷酸的cDNA。
-
Patent Agency Ranking
公开(公告)号：KR1020130055039A
公开(公告)日：2013-05-28
申请号：KR1020110118294
申请日：2011-11-14
Applicant: 대한민국(농촌진흥청장)
CPC classification number: C12Q1/6827 , C12Q1/6837 , C12Q1/6876 , C12Q2600/124
Abstract: PURPOSE: A genetic marker for identifying individual and bloodline of cattle is provided to improve reliability and to test DNA identity by alternating a functional individual identification tool and a DNA analysis method. CONSTITUTION: A marker for identifying individual and bloodline of cattle contains: a polynucleotide containing 8-500 continuous nucleotides with each SNP base among a polynucleotide selected from the group consisting of sequence numbers 1-36; or a complementary polynucleotide thereof. An SNP is 201th base. A microarray or a kit for identifying individual and bloodline of cattle contains the polynucleotide or a polypeptide encoded by the polynucleotide, and cDNA of the polynucleotide. A method for identifying individual in cattle comprises: a step of providing an isolated nucleic acid sample; and a step of determining allele genotype of SNP.
Abstract translation: 目的：提供用于鉴定牛的个体和血型的遗传标记，以通过交替功能性个体识别工具和DNA分析方法来提高可靠性和测试DNA鉴别。 构成：用于鉴定牛的个体和血型的标记物含有：选自序列号1-36的多核苷酸中含有每个SNP碱基的8-500个连续核苷酸的多核苷酸; 或其互补多核苷酸。 SNP是第201个基地。 用于鉴定牛的个体和血型的微阵列或试剂盒含有由多核苷酸编码的多核苷酸或多肽和多核苷酸的cDNA。 用于鉴定牛中个体的方法包括：提供分离的核酸样品的步骤; 以及确定SNP等位基因基因型的步骤。
-
公开(公告)号：KR1020110139011A
公开(公告)日：2011-12-28
申请号：KR1020100059238
申请日：2010-06-22
Applicant: 대한민국(농촌진흥청장)
CPC classification number: C12Q1/6827 , C12Q2600/156
Abstract: PURPOSE: A biomarker for diagnosing the content of pork marbling is provided to determine the content of pork marbling. CONSTITUTION: An SNP biomarker for determining the content of pork marbling contains one among sequences of sequence numbers 1-30. A method for selecting the SNP biomarker comprises: a step of determining SNPs relating to pork marbling content; a step of testing correlation with QTL(quantitative trait loci); and a step of analyzing the characteristic with QTL. A breeding pig is selected using the SNP biomarker. A kit for determining breeding pigs contains the SNP biomarker.
Abstract translation: 目的：提供用于诊断猪大理石花纹含量的生物标志物，以确定猪肉大理石花纹的含量。 构成：用于确定猪排大理石花纹的含量的SNP生物标志物包含序列号1-30的序列之一。 选择SNP生物标志物的方法包括：确定与猪排大花砾含量有关的SNP的步骤; 测定与QTL（数量性状位点）相关性的步骤; 并分析QTL特征的一个步骤。 使用SNP生物标志物选择繁殖猪。 用于确定繁殖猪的试剂盒含有SNP生物标志物。
-
公开(公告)号：KR1020110139009A
公开(公告)日：2011-12-28
申请号：KR1020100059236
申请日：2010-06-22
Applicant: 대한민국(농촌진흥청장)
CPC classification number: C12Q1/6827 , C12Q2600/156
Abstract: PURPOSE: A biomarker for diagnosing pork meat quality is provided to accurately measure genetic ability of a breeding pig and to determine the content of pork belly. CONSTITUTION: An SNP biomarker for determining the content of pork belly contains one or more of sequence numbers 1-10, containing quantitative trait loci(QTL) of pig chromosome No. 6. A method for selecting a biomarker comprises: a step of determining SNPs relating to pig meat quality; a step of detecting correlation with QTL; and a step of analyzing characteristic of pork belly content based on the result. A SNP biomarker is ALGA0103394, ALGA0118524, ALGA0123484, ASGA0029035, ASGA0029182, ASGA0029189, ASGA0029220, ASGA0095594, M1GA0008864, or MARC0043661.
Abstract translation: 目的：提供一种诊断猪肉质量的生物标志物，以准确测量养殖猪的遗传能力并确定猪肚的含量。 构成：用于测定猪肚含量的SNP生物标志物含有一个或多个序列号1-10，其含有猪染色体6的数量性状位点（QTL）。选择生物标志物的方法包括：测定SNP的步骤 涉及猪肉质量; 检测与QTL相关性的步骤; 并根据结果分析猪肚内容的特点。 SNP生物标志物是ALGA0103394，ALGA0118524，ALGA0123484，ASGA0029035，ASGA0029182，ASGA0029189，ASGA0029220，ASGA0095594，M1GA0008864或MARC0043661。
-
公开(公告)号：KR100981357B1
公开(公告)日：2010-09-14
申请号：KR1020100056566
申请日：2010-06-15
Applicant: 대한민국(농촌진흥청장)
Abstract: 본 발명은 한우 근육조직 부위별 특이 단백질 및 단백체의 특이적 조성을 구명하여 프로테옴 분석을 통해 근육의 부위를 판별할 수 있는 바이오 마커 단백질로서, 특히 한우 양지 판별용 바이오 마커 조성물에 관한 것이다.
본 발명에 의하면 한우 등심, 양지 및 홍두깨 근육조직에 대해 프로테옴 분석을 통해 부위판별이 가능하다. 더 나아가 본 발명에 의하면, 한우 등심, 양지 및 홍두깨 조직의 프로테옴 특성을 통한 축적조절기술 및 신약개발에 기초자료 제공할 수 있다.Abstract translation: 本发明涉及的九人于生物标志物蛋白的牛肌肉组织的位点特异性蛋白特异性和特异性组合物通过蛋白质组分析，以确定肌肉的地区，特别是牛肉音符确定的生物标志物为蛋白质组的组成。
-
-
-
-
-
-
-
-
-
Search Results
50
records
(took 0.032 seconds)
