公开(公告)号：KR101362549B1

公开(公告)日：2014-02-25

申请号：KR1020130002647

申请日：2013-01-09

Applicant: 성균관대학교산학협력단

Inventor： 정지훈 ,  이민상

IPC: B82B3/00 ,  B22F9/18

CPC classification number: B22F9/18 ,  A61K9/0009 ,  A61K9/1075 ,  A61K9/143 ,  B01J13/02 ,  B22F2001/0037 ,  B82Y30/00

Abstract: The present invention relates to a manufacturing method for gold nanoparticles which forms the nucleus of gold particles in the shells of micelles by using reductive micelles of nano-scale capturing antioxidants as a template and produces gold particles by growing the same. The gold nanoparticles manufactured by the present invention has projection structures molded on the shell and surface of the micelles by growing the nucleus of the gold particles after forming the nucleus of the gold particles along the high-branched surface structure of the micelles. The gold nanoparticles manufactured by the manufacturing method for gold nanoparticles of the present invention are identical to the surface structure of the micelles, thereby being able to be applied to the visualization of the surface structures of the micelles. The gold particles of the projection structures manufactured by the manufacturing method for gold nanoparticles are able to be applied as drug carriers and probe particles for a Raman spectrophotometer.

Abstract translation: 本发明涉及一种金纳米颗粒的制造方法，其通过使用纳米级捕获抗氧化剂的还原性胶束作为模板，通过生长金颗粒而形成胶束壳中的金颗粒的核。 通过本发明制造的金纳米颗粒通过沿着胶束的高支化表面结构形成金颗粒的核而生长金颗粒的核后，通过在胶粒的外壳和表面上模制凸起结构。 通过本发明的金纳米颗粒的制造方法制造的金纳米颗粒与胶束的表面结构相同，因此能够应用于胶束的表面结构的可视化。 通过金纳米颗粒的制造方法制造的投影结构的金颗粒能够用作拉曼分光光度计的药物载体和探针颗粒。