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公开(公告)号：KR1020170059928A
公开(公告)日：2017-05-31
申请号：KR1020170061215
申请日：2017-05-17
Applicant: 한국과학기술원 , 연세대학교 산학협력단
IPC: C12Q1/68 , G01N33/68 , A01K67/027
Abstract: 본발명은대뇌피질발달기형에의한난치성뇌전증과관련하여, 뇌전증을유발하는뇌 체성유전변이및 이의이용에관한것이다. 보다구체적으로, 본발명은염기서열의변이가일어난 mTOR(Mammalian target of rapamycin) 유전자또는염기서열의변이로인해아미노산서열의변이가일어난 mTOR 단백질에관한것이다. 또한, 본발명은상기유전자또는단백질을이용한대뇌피질발달기형에의한난치성뇌전증의진단기술에관한것이다. 또한, 본발명은유전자또는단백질을이용한대뇌피질발달기형에의한난치성뇌전증의유도기술에관한것이다.
Abstract translation: 本发明涉及导致脑卒中的脑体细胞遗传变异及其与由于大脑皮层发育异常而导致的顽固性脑卒中相关的用途。 更具体地，本发明涉及其中发生碱基序列突变的mTOR（雷帕霉素哺乳动物靶标）基因或其中氨基酸序列由于碱基序列突变而突变的mTOR蛋白。 本发明还涉及使用该基因或蛋白质引起的脑皮质发育畸形所致的难治性脑卒中的诊断技术。 本发明还涉及使用基因或蛋白质通过大脑皮层发育畸形诱导顽固性脑梗塞的技术。
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公开(公告)号：KR1020160108752A
公开(公告)日：2016-09-20
申请号：KR1020150031605
申请日：2015-03-06
Applicant: 한국과학기술원 , 연세대학교 산학협력단
IPC: C12N9/12 , C12Q1/68 , G01N33/53 , A01K67/027
CPC classification number: C12N9/12 , A01K67/0275 , A01K2267/0306 , C12N2310/16 , C12Q1/6883 , C12Q2525/205 , C12Q2600/112 , C12Y207/11001 , G01N33/53
Abstract: 본발명은염기서열의변이가일어난 mTOR 유전자또는염기서열의변이로인해아미노산서열의변이가일어난 mTOR 단백질, 이들을이용한난치성뇌전증또는국소피질이형성증의진단및 이용한난치성뇌전증또는국소피질이형성증의유도기술에관한것이다.
Abstract translation: 本发明涉及产生碱基序列或mTOR蛋白质变异的mTOR基因，其产生由碱基序列的变异引起的氨基酸序列的变异，使用该变异的顽固性癫痫或局灶性皮层发育异常，以及诱导 难治性癫痫或局灶性皮层发育不良的技术使用相同。
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公开(公告)号：KR101098234B1
公开(公告)日：2011-12-28
申请号：KR1020100034211
申请日：2010-04-14
Applicant: 한국과학기술원
Abstract: 본 발명은 IPTV 서비스를 업데이트하는 방법 및 서버에 관한 것으로, 보다 특정하게는 서버에서 IPTV 서비스를 업데이트하고 그 IPTV 서비스의 업데이트 여부를 IPTV 수신 단말에게 알리는 방법 및 서버에 관련된다. 본 발명의 실시 예에 따르면, 서비스 디스커버리 및 선택 기능을 지원하는 IPTV 제공서버는 브로드캐스트 컨텐츠 가이드의 업데이트를 즉각적으로 IPTV 수신 단말에게 알릴 수 있다. 또한, IPTV 수신 단말은 IPTV 제공서버로부터 수신되는 전송 스트림의 헤더를 확인하는 것으로, 어느 브로드캐스트 컨텐츠 가이드가 업데이트되었는 지를 즉시 파악하여 자신의 저장소에 업데이트할 수 있다.
Abstract translation: 用于更新IPTV服务的方法和服务器技术领域本发明涉及用于更新IPTV服务的方法和服务器，并且更具体地涉及用于更新服务器中的IPTV服务并且向IPTV接收终端通知IPTV服务是否被更新的方法和服务器。 根据本发明的实施例，支持服务发现和选择功能的IPTV提供服务器可以立即向IPTV接收终端通知广播内容指南的更新。 另外，IPTV接收终端可以通过检查从IPTV提供服务器接收到的传输流的报头来立即检查哪个广播内容指南已被更新，并且更新存储在其自己的存储库中的信息。
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公开(公告)号：KR1020110020069A
公开(公告)日：2011-03-02
申请号：KR1020090077769
申请日：2009-08-21
Applicant: 한국과학기술원
IPC: H04N21/262 , H04N21/2381 , G06Q30/02
CPC classification number: H04N21/262 , G06Q30/0256 , H04N21/2381
Abstract: PURPOSE: An advertisement providing system based on a user's reaction, and a method thereof are provided to reflect the user's reaction in short time by selecting an advertisement according to the user's input keyword. CONSTITUTION: A keyword extractor(110) extracts the search keyword from a metadata of the transmitted broadcasting content. A web page searcher(120) searches a web page related with the keyword, and selects the keyword. The web page searcher extracts keywords which are related with an advertisement from the searched web page. An advertisement unit(140) searches an advertisement which is related with the keywords. A content service unit(150) offers the media content.
Abstract translation: 目的：提供基于用户反应的广告提供系统及其方法，以通过根据用户的输入关键字选择广告来在短时间内反映用户的反应。 构成：关键词提取器（110）从所发送的广播内容的元数据中提取搜索关键字。 网页搜索器（120）搜索与关键字相关的网页，并选择该关键字。 网页搜索者从搜索到的网页中提取与广告相关的关键词。 广告单元（140）搜索与关键字相关的广告。 内容服务单元（150）提供媒体内容。
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公开(公告)号：KR100864607B1
公开(公告)日：2008-10-22
申请号：KR1020070053080
申请日：2007-05-31
Applicant: 한국과학기술원
Abstract: An apparatus and a method for measuring inertia by using a slope sensor and an angular velocity sensor for a humanoid biped walking robot are provided to facilitate expansion of a system by minimizing an additional interconnection through using controller area network communication. An apparatus(100) for measuring inertia by using a slope sensor and an angular velocity sensor for a humanoid biped walking robot comprises a slope sensor(120) and angular velocity sensors(130,131). The slope sensor measures a slope of a robot relative to the gravity. The angular velocity sensors measure angular velocity of the robot relative to the gravity. A complementary filter receives and filters the slope and angular velocity signals measured in realtime by the slope and angular velocity sensors. A digital signal processor is connected to the complementary filter to perform A/D conversion relative to the slope and angular velocity signals.
Abstract translation: 提供了一种用于通过使用用于人形二足动作机器人的斜率传感器和角速度传感器来测量惯性的装置和方法，以通过使用控制器区域网络通信最小化附加互连来促进系统的扩展。 用于通过使用倾斜传感器和人形二足步行机器人的角速度传感器来测量惯性的装置（100）包括倾斜传感器（120）和角速度传感器（130,131）。 斜率传感器测量机器人相对于重力的斜率。 角速度传感器测量机器人相对于重力的角速度。 互补滤波器接收并过滤由斜率和角速度传感器实时测量的斜率和角速度信号。 数字信号处理器连接到互补滤波器，以相对于斜率和角速度信号执行A / D转换。
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Patent Agency Ranking
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公开(公告)号：KR101838394B1
公开(公告)日：2018-03-14
申请号：KR1020160110128
申请日：2016-08-29
Applicant: 연세대학교 산학협력단 , 한국과학기술원
IPC: C12Q1/68 , A01K67/027
Abstract: 본발명은뇌실하영역(subventricular zone, SVZ)에서암 유전자돌연변이발현수준을측정하여교모세포종(gliblastoma; GBM)의조직기원을예측하는방법을제공하고, 더나아가상기교모세포종진단을위한정보를제공하는방법을제공한다. 또한, 암유전자돌연변이를주입하여교모세포종이유도된동물모델을제공한다. 상기뇌실하영역(Subventricular Zone; SVZ)의특정암 유전자돌연변이의발현수준을측정하여 IDH-정상교모세포종의조직기원을예측함을통해상기교모세포종에대한적절한치료전략수립을가능하게할 수있다. 또한, 본발명에따른뇌실하영역의특정돌연변이유전자를포함하는동물모델을통하여교모세포종환자의발생원인, 치료및 예방방법에대한연구를수행하여교모세포종을극복할수 있는연구기반을제시할수 있다.
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公开(公告)号：KR101678961B1
公开(公告)日：2016-11-23
申请号：KR1020140107639
申请日：2014-08-19
Applicant: 한국과학기술원 , 연세대학교 산학협력단
Abstract: 본발명은뇌전증유도용조성물및 이의이용에관한것이다. 보다구체적으로, 본발명은염기서열의변이가일어난 mTOR(Mammalian target of rapamycin) 유전자또는아미노산서열의변이가일어난 mTOR 단백질을포함하는뇌전증유도용조성물, 상기유전자를포함하는재조합벡터, 상기벡터가도입된세포또는배아, 상기벡터로형질전환된뇌전증이유도된동물및 이의제조방법. 그리고이를이용한뇌전증치료제의스크리닝방법에관한것이다.
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公开(公告)号：KR1020150026623A
公开(公告)日：2015-03-11
申请号：KR1020130105712
申请日：2013-09-03
Applicant: 한국과학기술원 , 연세대학교 산학협력단
CPC classification number: C07K14/47 , C12N15/115 , C12Q1/6844 , C12Q1/6883 , G01N33/5302 , G01N33/5308
Abstract: The present invention relates to a biomarker for diagnosing epilepsy, and a usage thereof. More specifically, the present invention relates to an mammalian target of rapamycin (mTOR) gene having variation in the base sequence, or an mTOR protein having variation in the amino acid sequence due to variation of the base sequence. Also, the present invention relates to a composition and a kit for diagnosing epilepsy including formulations capable of detecting the gene or the protein. Furthermore, the present invention relates to a method of detecting the gene and the protein which are a biomarker for diagnosing epilepsy from a sample of a patient in order to provide information necessary for the epilepsy diagnosis. According to an embodiment of the present invention, the biomarker for diagnosing epilepsy is a gene consisting of a base sequence including at least one type of variation selected from the group consisting of the substitution of guanine (G) at the 4448th position with adenine (A), the substitution of G at the 7255th position with A, and the substitution of thymine (T) at the 7280th position with cytosine (C) in the base sequence of sequence 1.
Abstract translation: 本发明涉及用于诊断癫痫的生物标志物及其用途。 更具体地，本发明涉及具有碱基序列变异的雷帕霉素（mTOR）基因的哺乳动物靶标或由于碱基序列的变化而具有氨基酸序列变化的mTOR蛋白质。 此外，本发明还涉及用于诊断癫痫的组合物和试剂盒，其包括能够检测基因或蛋白质的制剂。 此外，本发明涉及一种检测基因和蛋白质的方法，所述基因和蛋白质是用于诊断来自患者样品的癫痫的生物标志物，以提供癫痫诊断所需的信息。 根据本发明的实施方案，用于诊断癫痫的生物标志物是由碱基序列组成的基因，所述碱基序列包括至少一种类型的变体，所述变体选自第4448位的鸟嘌呤（G）与腺嘌呤（A ），用A取代第7255位的G，并在序列1的碱基序列中用胞嘧啶（C）取代第7280位的胸腺嘧啶（T）。
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公开(公告)号：KR101131244B1
公开(公告)日：2012-04-12
申请号：KR1020090077769
申请日：2009-08-21
Applicant: 한국과학기술원
IPC: H04N21/262 , H04N21/2381 , G06Q30/02
Abstract: PURPOSE: An advertisement providing system based on a user's reaction, and a method thereof are provided to reflect the user's reaction in short time by selecting an advertisement according to the user's input keyword. CONSTITUTION: A keyword extractor(110) extracts the search keyword from a metadata of the transmitted broadcasting content. A web page searcher(120) searches a web page related with the keyword, and selects the keyword. The web page searcher extracts keywords which are related with an advertisement from the searched web page. An advertisement unit(140) searches an advertisement which is related with the keywords. A content service unit(150) offers the media content.
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