Abstract:
The present invention relates to a read sequence alignment method and a read sequence alignment apparatus using the same and, more specifically, to a method for aligning a read sequence with respect to a reference genome using a seed and a read sequence alignment apparatus using the same. The read sequence alignment apparatus according to the present invention comprises a seed creating unit for creating seeds from read sequences; a duplicate seed removal unit for searching duplicate seeds among the seeds, indexing the seeds based on information on the duplicate seeds and generating a seed set obtained by removing the duplicate seeds from the seeds; a seed alignment unit for aligning the seed set with respect to the reference genome; and a read sequence alignment unit for aligning the read sequences with respect to the reference genome by referring to the index result of the seeds and the alignment result of the seed set. The read sequence alignment method and the read sequence alignment apparatus using the same according to the present invention can perform efficient calculation using correlation among the seeds.
Abstract:
PURPOSE: A gait training system, data processing unit thereof, and an operating method of the data processing unit are provided to prevent generation of disease relating to a musculoskeletal system. CONSTITUTION: A wireless communication unit(210) receives acceleration data from a gait sensor device(100). The wireless communication unit receives acceleration data of the moving direction of a pedestrian, acceleration data of the left and right direction of a pedestrian and acceleration data of the upward and downward direction of a pedestrian from the gait sensor device. A 11-shaped gait detection unit(230) judges whether a pedestrian walk in a 11 shape or not using the acceleration data. A display unit(240) provides the information of whether the 11-shaped gait is kept or not. [Reference numerals] (100) Gait sensor device; (110) Acceleration sensor device; (120,210) Wireless communication unit; (200) Data processing device; (220) Preprocessing unit; (230) 11-shaped gait detection unit; (240) Display unit; (250) Data storage unit; (260) Control unit
Abstract:
PURPOSE: A method for analyzing a walking pattern is provided to calculate correctly a moving track of a COP(Center Of Pressure) by reflecting a characteristic of an FSR(Force Sensing Resistor) sensor and a characteristic of a frame structure of a foot. CONSTITUTION: A plurality of FSR sensors measures a foot pressure value(S310). The output values of the FSR sensors are pre-processed(S320). A maximum pressure local region is searched(S330). A COP calculation process for the maximum pressure local region is performed(S340). The calculated COP is added to a COP moving track (S350).
Abstract:
PURPOSE: Smart footwear is provided to remove an inconvenience of elderly people wearing new apparatus and to measure an active mass and a sense of isolation in a daily life. CONSTITUTION: The smart footwear includes a film type leading sensor(110), which measures a change of power added to a smart footwear user as a resistance value, an acceleration sensor(120) measuring an acceleration value according to movement changes of the user, and a microcontroller(130), which predicts a current state and activity mass of the user by using the resistance value and the acceleration value, and creates status information and active mass information of user.
Abstract:
PURPOSE: A motion recognizing system using footwear for recognizing a motion is provided to correct the posture of a wearer by using information about the motion of a foot, a three dimensional position and the balance of the body of the wearer. CONSTITUTION: Motion recognition footwear(10) measures a height, an acceleration, and the pressure of a foot, preprocesses the measured signal, and transmits the signal to the outside. An information processing terminal(20) analyzes the signal received from the motion recognition footwear, obtains the three dimensional position, the motion of the foot, and the balance of the body of wearer, and provides an application service based on the obtained information.
Abstract:
A method for clustering gene using gene expression profile is provided to obtain an accurate clustering result with low calculation complexity without directly designating complicated and detrimental input variations determining quality of a clustering result by clustering a time series gene expression profile data set into a gene group having the similar function. A method for clustering gene using gene expression profile comprises the steps of: (a) calculating a parameter value of each orders of a linear regression model when the gene expression profile is inputted; (b) calculating an F-distribution based probability regarding each of the parameter value calculated linear regression model; and (c) after selecting the linear regression model having a minimum value of the calculated F-distribution based probability, clustering the gene in accordance with the order of the selected linear regression model, wherein the gene is clustered by an increase function or a decrease function according to a sign of the corresponding parameter value when the order of the finally selected linear regression model is 1st(linear) or at least 3rd. or is clustered by a concave function or a convex function according to the sign of the corresponding parameter value when the order of the finally selected linear regression model is 2nd(parabola).
Abstract:
본 발명은 유전자의 발현 패턴 데이터와 단백질 상호작용 데이터를 이용하여 생물학적으로 같은 특정 목적을 수행하는 패스웨이를 예측하는 방법 및 시스템에 관한 것이다. 본 발명에 따른 유전자의 패스웨이 예측 방법은 유전자의 발현 패턴 데이터로부터 유전자 간 패스웨이 추출 알고리즘을 통해 부분 패스웨이를 생성하고, 이 부분 패스웨이를 매칭시켜 그래프 구조로 표시하는 제 1 단계, 유전자의 단백질 상호작용 데이터로부터 패스웨이 추출 알고리즘을 통해 부분 패스웨이를 생성하고, 이 부분 패스웨이를 매칭시켜 그래프 구조로 표시하는 제 2 단계, 및 제 1 단계의 그래프 구조와 제 2 단계의 그래프 구조를 그래프 매칭 알고리즘을 통해 융합하여 그래프 구조로 표시하는 제 3 단계를 포함한다. 이와 같이 본 발명에 따른 패스웨이 예측 방법은 질병 발병 기전이나 경로에 대한 것을 생물학적인 많은 실험을 통한 것이 아니라, 해당 mRNA 발현 패턴과 기존에 밝혀져 있는 단백질 상호작용 데이터를 통해서 예측함으로 시간과 비용을 효율적으로 줄일 수 있으며, 또한, 두 가지 이상의 생물학적 데이터를 사용함으로써 예측 결과의 신뢰성이 향상될 수 있다. 유전자, 발현 패턴, 단백질 상호작용, 패스웨이, 예측