公开(公告)号：EP1380843A3

公开(公告)日：2010-01-13

申请号：EP03021137.9

申请日：1993-03-24

Applicant: ABBOTT LABORATORIES

Inventor： Clark, Frederic L. ,  Clift, Gilbert ,  Hendrick, Kendall B. ,  Kanewske, William J.III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  Mitchell, James E. ,  Moore, Larry W ,  Pennington, Charles D. ,  Walker, Edna S. ,  Smith, Jane B. ,  Tayi, Apparao ,  Vaught, James A. ,  Yost, David A ,  Merriam, Richard A. ,  Walker, Donny Ray ,  McDowell, Douglas D. ,  Rumbaugh, William A. ,  Clemens, John M.

IPC: G01N35/02

CPC classification number: G01N35/0095 ,  B01L3/08 ,  B01L3/5025 ,  B01L3/5085 ,  B01L3/50853 ,  B01L9/06 ,  B01L2200/142 ,  B01L2300/042 ,  B01L2300/043 ,  B29C45/00 ,  B29K2995/0032 ,  B29L2023/22 ,  G01N21/03 ,  G01N21/253 ,  G01N33/5302 ,  G01N33/537 ,  G01N33/538 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0092 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2035/00168 ,  G01N2035/00277 ,  G01N2035/00287 ,  G01N2035/00356 ,  G01N2035/00386 ,  G01N2035/00455 ,  G01N2035/00475 ,  G01N2035/00495 ,  G01N2035/00524 ,  G01N2035/00752 ,  G01N2035/0093 ,  G01N2035/0405 ,  G01N2035/0436 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0448 ,  G01N2035/0453 ,  G01N2035/0465 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

Abstract: A liquid level sensing device for sensing the level of a liquid in a container and an automated, continuous and random access analytical system containing such liquid level sensing device and capable of simultaneously effecting multiple assays of a plurality of liquid samples are disclosed. The liquid level sensing device comprises: (a) means for producing an electrical sinusoidal signal; (b) means for evaluating the amount of signal as it propagates from a probe to a sense antenna; (c) circuit means for creating an electrical signal wherein said electrical signal changes when a probe contacts liquid; (d) signal processing means for enhancing the electrical signal and for degrading and suppressing signals not associated with the probe contacting said liquid; (e) decision circuit means for causing a basic digital output indicating either the presence or absence of liquid; and (f) means for utilizing the digital signal for controlling motion, and wherein said sensing device detects signal change and rate of signal change.

公开(公告)号：EP1205756B1

公开(公告)日：2006-04-12

申请号：EP02001046.8

申请日：1994-09-22

Applicant: ABBOTT LABORATORIES

Inventor： Clark, Frederick L. ,  Clemens, John M. ,  Hance, Robert B. ,  Hendrick, Kendall B. ,  Tayi, Apparao ,  Kanewske, William J., III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  McDowell, Douglas D. ,  Merriam, Richard A. ,  Moore, Larry W. ,  Oleksak, Carl M. ,  Pennington, Charles D. ,  Raymoure, William J. ,  Rumbaugh, William D. ,  Schmidt, Linda S. ,  Schrier, Paul R. ,  Smith, Jane B. ,  Spronk, Adrian M. ,  Walker, Edna S. ,  Vaught, James A. ,  Vickstrom, Richard L. ,  Walker, Donny Ray ,  Watkins, William E., III ,  Winter, Gary E. ,  Wohlford, Robert A. ,  Clift, Gilbert ,  Cloonan, Kevin M. ,  Mitchell, James E. ,  Stanton, Alyn K. ,  Yost, David A. ,  Hills, David B.

IPC: G01N35/10 ,  G01F23/284

CPC classification number: G01N35/0092 ,  B01F11/0022 ,  B01L3/5025 ,  B29C45/00 ,  G01N21/6445 ,  G01N21/6452 ,  G01N21/76 ,  G01N33/5302 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2021/6482 ,  G01N2035/00148 ,  G01N2035/00356 ,  G01N2035/0405 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0446 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

公开(公告)号：EP1028320B1

公开(公告)日：2006-03-01

申请号：EP00108051.4

申请日：1994-09-22

Applicant: ABBOTT LABORATORIES

Inventor： Clark, Frederick L. ,  Clemens, John M. ,  Hance, Robert B. ,  Hendrick, Kendall B. ,  Tayi, Apparao ,  Kanewske, William J. III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  McDowell, Douglas D. ,  Merriam, Richard A. ,  Moore, Larry W. ,  Oleksak, Carl M. ,  Pennington, Charles D. ,  Raymoure, William J. ,  Rumbaugh, William D. ,  Schmidt, Linda S. ,  Schrier, Paul R. ,  Smith B., Jane ,  Spronk, Adrian M. ,  Walker, Edna S. ,  Vaught, James A. ,  Vickstrom Richard L. ,  Walker, Donny Ray ,  Watkins, William E. III ,  Winter, Gary E. ,  Wohlford, Robert A. ,  Clift, Gilbert ,  Cloonan, Kevin M. ,  Mitchell, James E. ,  Stanton, Alyn K. ,  Yost, David A. ,  Hills, David B.

IPC: G01N35/02

CPC classification number: G01N35/0092 ,  B01F11/0022 ,  B01L3/5025 ,  B29C45/00 ,  G01N21/6445 ,  G01N21/6452 ,  G01N21/76 ,  G01N33/5302 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2021/6482 ,  G01N2035/00148 ,  G01N2035/00356 ,  G01N2035/0405 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0446 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

公开(公告)号：EP1450161A8

公开(公告)日：2004-11-10

申请号：EP04010901.9

申请日：1993-03-24

Applicant: ABBOTT LABORATORIES

Inventor： Clark, Frederic L. ,  Clift, Gilbert ,  Hendrick, Kendall B. ,  Kanewske, William J. III. ,  Lagocki, Peter A. ,  Martin, Richard R. ,  Mitchell, James E. ,  Moore, Larry W. ,  Pennington, Charles D. ,  Walker, Edna S. ,  Smith, Jane B. ,  Tayi, Apparao ,  Vaught, James A. ,  Yost, David A. ,  Winter, Gary E. ,  Hance, Robert B. ,  Stanton, Alyn K. ,  Oleksak, Carl M. ,  Watkins, William E. III. ,  Vickstrom, Richard L. ,  Cloonan, Kevin M. ,  Wohlford Robert A. ,  Hills, David B. Jr. ,  Schrier, Paul R. ,  Rumbaugh, William

IPC: G01N35/02 ,  B65B7/00

CPC classification number: G01N21/0303 ,  B01L3/08 ,  B01L3/5025 ,  B01L3/5085 ,  B01L3/50853 ,  B01L9/06 ,  B01L2200/142 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/043 ,  G01N21/253 ,  G01N33/5302 ,  G01N33/537 ,  G01N33/538 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0092 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/026 ,  G01N35/1004 ,  G01N2001/007 ,  G01N2035/00287 ,  G01N2035/00356 ,  G01N2035/00386 ,  G01N2035/00455 ,  G01N2035/00475 ,  G01N2035/00495 ,  G01N2035/00524 ,  G01N2035/00752 ,  G01N2035/0093 ,  G01N2035/0405 ,  G01N2035/0436 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0448 ,  G01N2035/0453 ,  G01N2035/0465 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

Abstract: A method for controlling evaporation and contamination of reagents used in automated diagnostic systems is disclosed as well as an apparatus for opening and closing reagent containers contained within a reagent pack having cover and cap means for such controlling of evaporation and contamination. The method comprises (a) moving reagent packs containing reagents in closed reagent containers mounted in a reagent pack carousel to an opening and closing station, (b) forcing open the evaporatively closed reagent containers contained in the reagent pack by the opening and closing station, (c) locking in an open position the reagent containers cover and cap which is affixed to the reagent containers, (d) moving the locked open reagent containers from the opening and closing station on the reagent pack carousel to a position wherein the system has access to the reagents, (e) withdrawing reagents from the reagent containers for system use, (f) returning the reagent pack and reagent containers on the reagent pack carousel to the opening and closing station, (g) unlocking the lock open cover and cap of the reagent containers, (h) force closing the cover and cap of the reagent containers of the reagent pack, and (i) removing the reagent pack from the opening and closing station.

Abstract translation: 公开了一种用于控制自动诊断系统中使用的试剂的蒸发和污染的方法以及一种用于打开和关闭容纳在试剂包内的试剂容器的设备，该试剂容器具有用于控制蒸发和污染的盖和盖装置。 该方法包括：（a）将包含试剂的试剂包在安装在试剂包转盘中的封闭的试剂容器中移动到打开和关闭站，（b）通过打开和关闭站强制打开包含在试剂包中的蒸发封闭的试剂容器， （c）将试剂容器盖和盖固定在试剂容器上的锁定打开位置，（d）将锁定的打开的试剂容器从试剂容器转盘上的打开和关闭站移动到系统可以进入的位置 （e）从用于系统使用的试剂容器中取出试剂，（f）将试剂包转盘上的试剂包和试剂容器返回到打开和关闭站，（g）解锁锁定打开盖和盖 试剂容器，（h）强制关闭试剂包的试剂容器的盖子和盖子，以及（i）从开闭站取出试剂包。

公开(公告)号：EP1450162A3

公开(公告)日：2004-09-15

申请号：EP04010903.5

申请日：1993-03-24

Applicant: ABBOTT LABORATORIES

Inventor： Clark, Frederick L. ,  Clift, Gilbert ,  Hendrick, Kendall B. ,  Kanewske, William J. III. ,  Lagocki, Peter A. ,  Martin, Richard R. ,  Mitchell, James E. ,  Moore, Larry W. ,  Pennington, Charles D. ,  Walker, Edna S. ,  Smith, Jane B. ,  Tayi, Apparao ,  Vaught, James A. ,  Yost, David A. ,  Rumbaugh, William ,  Winter, Gary E. ,  Hance, Robert B. ,  Stanton, Alyn K. ,  Oleksak, Carl M. ,  Watkins, William E. III. ,  Vickstrom, Richard L. ,  Cloonan, Kevin M. ,  Wohlford Robert A. ,  Hills, David B. Jr. ,  Schrier, Paul R.

IPC: G01N35/04 ,  B65G47/14 ,  B65G47/256

CPC classification number: G01N21/0303 ,  B01L3/08 ,  B01L3/5025 ,  B01L3/5085 ,  B01L3/50853 ,  B01L9/06 ,  B01L2200/142 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/043 ,  G01N21/253 ,  G01N33/5302 ,  G01N33/537 ,  G01N33/538 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0092 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/026 ,  G01N35/1004 ,  G01N2001/007 ,  G01N2035/00287 ,  G01N2035/00356 ,  G01N2035/00386 ,  G01N2035/00455 ,  G01N2035/00475 ,  G01N2035/00495 ,  G01N2035/00524 ,  G01N2035/00752 ,  G01N2035/0093 ,  G01N2035/0405 ,  G01N2035/0436 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0448 ,  G01N2035/0453 ,  G01N2035/0465 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

Abstract: A cartridge feeder apparatus for automated diagnostic systems is disclosed. The apparatus comprises a cartridge hopper means for receiving, storing and feeding cartridges (68) to a cartridge orientation mechanism, the cartridge orientation mechanism comprised of two opposed engageable orientation means (239) for engaging and disengaging a cartridge at each end of the cartridge. The cartridge has a funnel opening at a first end and a generally flat bottom at a second end.

Abstract translation: 公开了一种用于自动诊断系统的盒式供料器设备。 该装置包括一个用于容纳，存储盒子并将盒子（68）供给盒子定位机构的盒子盒装置，盒子定位机构包括两个相对的可啮合定向装置（239），用于啮合和脱离盒子两端的盒子。 盒在第一端具有漏斗开口，在第二端具有通常平坦的底部。

公开(公告)号：EP1450161A2

公开(公告)日：2004-08-25

申请号：EP04010901.9

申请日：1993-03-24

Applicant: ABBOTT LABORATORIES

Inventor： Clark, Frederick L. ,  Clift, Gilbert ,  Hendrick, Kendall B. ,  Kanewske, William J. III. ,  Lagocki, Peter A. ,  Martin, Richard R. ,  Mitchell, James E. ,  Moore, Larry W. ,  Pennington, Charles D. ,  Walker, Edna S. ,  Smith, Jane B. ,  Tayi, Apparao ,  Vaught, James A. ,  Yost, David A. ,  Winter, Gary E. ,  Hance, Robert B. ,  Stanton, Alyn K. ,  Oleksak, Carl M. ,  Watkins, William E. III. ,  Vickstrom, Richard L. ,  Cloonan, Kevin M. ,  Wohlford Robert A. ,  Hills, David B. Jr. ,  Schrier, Paul R. ,  Rumbaugh, William

IPC: G01N35/02 ,  B65B7/00

CPC classification number: G01N21/0303 ,  B01L3/08 ,  B01L3/5025 ,  B01L3/5085 ,  B01L3/50853 ,  B01L9/06 ,  B01L2200/142 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/043 ,  G01N21/253 ,  G01N33/5302 ,  G01N33/537 ,  G01N33/538 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0092 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/026 ,  G01N35/1004 ,  G01N2001/007 ,  G01N2035/00287 ,  G01N2035/00356 ,  G01N2035/00386 ,  G01N2035/00455 ,  G01N2035/00475 ,  G01N2035/00495 ,  G01N2035/00524 ,  G01N2035/00752 ,  G01N2035/0093 ,  G01N2035/0405 ,  G01N2035/0436 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0448 ,  G01N2035/0453 ,  G01N2035/0465 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

Abstract: A method for controlling evaporation and contamination of reagents used in automated diagnostic systems is disclosed as well as an apparatus for opening and closing reagent containers contained within a reagent pack having cover and cap means for such controlling of evaporation and contamination. The method comprises (a) moving reagent packs containing reagents in closed reagent containers mounted in a reagent pack carousel to an opening and closing station, (b) forcing open the evaporatively closed reagent containers contained in the reagent pack by the opening and closing station, (c) locking in an open position the reagent containers cover and cap which is affixed to the reagent containers, (d) moving the locked open reagent containers from the opening and closing station on the reagent pack carousel to a position wherein the system has access to the reagents, (e) withdrawing reagents from the reagent containers for system use, (f) returning the reagent pack and reagent containers on the reagent pack carousel to the opening and closing station, (g) unlocking the lock open cover and cap of the reagent containers, (h) force closing the cover and cap of the reagent containers of the reagent pack, and (i) removing the reagent pack from the opening and closing station.

Abstract translation: 公开了一种用于控制自动诊断系统中使用的试剂的蒸发和污染的方法，以及用于打开和关闭包含在具有盖和用于控制蒸发和污染的盖装置的试剂盒内的试剂容器的装置。 该方法包括：（a）将安装在试剂盒转盘中的封闭式试剂容器中的试剂盒移动到开闭站，（b）通过开闭站强制打开包含在试剂包中的蒸发封闭的试剂容器， （c）在打开位置锁定固定在试剂容器上的试剂容器盖和帽，（d）将锁定的打开的试剂容器从试剂盒转盘上的打开和关闭站移动到系统有通路的位置 （e）从用于系统使用的试剂容器中取出试剂;（f）将试剂盒转盘上的试剂盒和试剂容器返回到打开和关闭站，（g）将锁定开盖和盖 试剂容器（h）强制关闭试剂容器的试剂容器的盖和盖，以及（i）从打开和关闭工位移除试剂盒。

公开(公告)号：EP1205756A3

公开(公告)日：2002-08-07

申请号：EP02001046.8

申请日：1994-09-22

Applicant: Abbott Laboratories

Inventor： Clark, Frederick L. ,  Clemens, John M. ,  Hance, Robert B. ,  Hendrick, Kendall B. ,  Tayi, Apparao ,  Kanewske, William J., III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  McDowell, Douglas D. ,  Merriam, Richard A. ,  Moore, Larry W. ,  Oleksak, Carl M. ,  Pennington, Charles D. ,  Raymoure, William J. ,  Rumbaugh, William D. ,  Schmidt, Linda S. ,  Schrier, Paul R. ,  Smith, Jane B. ,  Spronk, Adrian M. ,  Walker, Edna S. ,  Vaught, James A. ,  Vickstrom, Richard L. ,  Walker, Donny Ray ,  Watkins, William E., III ,  Winter, Gary E. ,  Wohlford, Robert A. ,  Clift, Gilbert ,  Cloonan, Kevin M. ,  Mitchell, James E. ,  Stanton, Alyn K. ,  Yost, David A. ,  Hills, David B.

IPC: G01N35/10 ,  G01F23/284

CPC classification number: G01N35/0092 ,  B01F11/0022 ,  B01L3/5025 ,  B29C45/00 ,  G01N21/6445 ,  G01N21/6452 ,  G01N21/76 ,  G01N33/5302 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2021/6482 ,  G01N2035/00148 ,  G01N2035/00356 ,  G01N2035/0405 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0446 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

Abstract: The invention relates to an automated liquid level sensing system for detecting the presence of liquid in a container, said liquid level sensing system comprising: a vertically oriented, electrically conductive probe positioned above said container; means for vertically moving said probe into and out of said container; a signal source electrically connected to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; a receiving antenna positioned below said container for receiving said transmitted electrical signal; means for analyzing said received electrical signal for indications that said probe has contacted liquid in said container; means for transferring said received electrical signal from said receiving antenna to said analyzing means; and means for indicating that liquid has been detected. Further, the invention also provides for a method for automatically detecting the presence of liquid in a container, said method comprising the steps of: vertically positioning an electrically conductive probe above said container; vertically moving said probe into and out of said container; electrically connecting a signal source to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; positioning a receiving antenna below said container for receiving said transmitted electrical signal; analyzing said received electrical signal for indications that said probe has contacted liquid in said container; transferring said received electrical signal from said receiving antenna to said analyzing means; and indicating that liquid has been detected.