公开(公告)号：DE59407859D1

公开(公告)日：1999-04-08

申请号：DE59407859

申请日：1994-05-28

Applicant: BASF AG

Inventor： EBEL KLAUS DR ,  SCHROEDER JUERGEN DR ,  GROENING CARSTEN DR ,  DOCKNER TONI DR ,  MERKLE HANS RUPERT DR

IPC: B01J21/12 ,  C07B61/00 ,  C07D231/12 ,  C07D521/00

公开(公告)号：DE19735682A1

公开(公告)日：1999-02-25

申请号：DE19735682

申请日：1997-08-19

Applicant: BASF AG

Inventor： MERKLE HANS RUPERT DR ,  WOERZ OTTO DR ,  FRETSCHNER ERICH ,  HANSEN HANSPETER DR ,  MUELLER ALBRECHT DR ,  BENZ KURT

IPC: C07D285/24 ,  C07D285/16

Abstract: Production of 3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one-2,2-dioxide (I) from anthranilic acid isopropylamide (II) in a single step is claimed. Production of the benzothiadiazinone-dioxide of formula (I) comprises reacting anthranilic acid isopropylamide of formula (II) simultaneously with (a) sulphur trioxide or chlorosulphonic acid in the presence of an organic base, or with adducts of SO3 and organic base; and (b) phosphorus oxychloride. The reaction is carried out at from 50 deg C to the reflux temperature, and the (I) produced is optionally converted to its salt.

公开(公告)号：CZ239597A3

公开(公告)日：1998-06-17

申请号：CZ239597

申请日：1996-02-01

Applicant: BASF AG

Inventor： MERKLE HANS RUPERT DR ,  DUREIN ALFONS ,  HANSEN HANSPETER DR ,  JAGER KARL-FRIDRICH DR

IPC: A01N43/00 ,  C07D285/16

Abstract: Prepn. of 3-isopropyl-2,1,3-benzothiadiazin-4-one-2,2-dioxide salts (A) of formula (I; Q = NHR1R2R3) comprises reacting 3-isopropyl-2,1,3-benzothiadiazin-4-one-2,2-dioxide of formula (IIa) with an amine of formula NR1R2R3 (IIIa) in an organic solvent. R1-R3 = H or lower (hydroxy)alkyl. Also claimed is the prepn. of salts (B) of formula (I; Q = NR1R2R3R4) by reacting (IIa) with (IIIa) or an ammonium salt of formula (NR1R2R3R4ÜnX (IIIb) in a solvent that is practically immiscible with water, opt. in the presence of water; and extracting (I) with water. R4 = as R1; X = the anion of an acid with pKa greater than 4 or esp. the OH ion; n = the charge on X. Also claimed is the prepn. of (B) by reacting (IIa) with (IIIb), or (I; Q = Na) with an ammonium salt of formula (NR1R2R3R4ÜmY (IIIc), in water. Y = the anion of an acid; m = the charge on Y.

公开(公告)号：DE19509958A1

公开(公告)日：1996-09-19

申请号：DE19509958

申请日：1995-03-18

Applicant: BASF AG

Inventor： MERKLE HANS RUPERT DR ,  FRETSCHNER ERICH ,  SCHROEDER JUERGEN DR

IPC: C07D231/12 ,  C07D521/00

Abstract: The prepn. of an N-substd. pyrazole deriv. of formula (I) comprises reacting pyrazole deriv. of formula (II) with an alcohol of formula R1OH (III) at 50-400 deg C in the presence of a catalyst. The mole ratio (II): (III) is 0.001-1:1 and reaction is carried out in the liq. phase at a pressure of below atmos. to 250 bar. The catalyst is an acid and/or its alkyl ester or anhydride. The mole ratio catalyst:(II) is 0.0001-0.5:1. R1 = 1-12C alkyl or 7-20C phenylalkyl; R2-R4 = H, 1-12C alkyl, 7-20C phenylalkyl or opt. substd. aryl.

公开(公告)号：ES2074988T3

公开(公告)日：1995-10-01

申请号：ES88108661

申请日：1988-05-31

Applicant: BASF AG

Inventor： MERKLE HANS RUPERT DR ,  MULLER ALBRECHT DR ,  REISSENWEBER GERNOT DR

IPC: B01J27/08 ,  C07B61/00 ,  C07D215/04 ,  C07D215/18

Abstract: Quinolines are prepared by reaction of anilines with alpha , beta -unsaturated aldehydes or ketones in approximately 70 to 85 % by weight sulphuric acid in the presence of catalytic amounts of iodine at elevated temperature.

公开(公告)号：ES2062181T3

公开(公告)日：1994-12-16

申请号：ES90110517

申请日：1990-06-02

Applicant: BASF AG

Inventor： MERKLE HANS RUPERT DR ,  FRETSCHNER ERICH

IPC: C07D231/06 ,  C07D231/12

Abstract: Pyrazole and its derivs. (I) are produced by dehydrogenation of the corresp. 2-pyrazoline (II) with the aid of sulphuric acid in the presence of iodine or an iodine cpd. (III) at 50-250 deg.C. (II) is produced in situ in the reaction medium by reaction of glycerol or acrolein or a deriv. thereof with hydrazine or a hydrazine deriv.; amt. of (III) is 0.01-10 mol. equiv. w.r.t. (II) or the corresp. hydrazine; 30-99 wt.% H2SO4 is used.

公开(公告)号：ES2056537T3

公开(公告)日：1994-10-01

申请号：ES91114026

申请日：1991-08-22

Applicant: BASF AG

Inventor： MERKLE HANS RUPERT DR ,  FRETSCHNER ERICH

IPC: B01J27/06 ,  C07B61/00 ,  C07D231/12 ,  C07D521/00

Abstract: Production of 3-methylpyrazole and its derivatives by reacting butenediols or ethynylalkylcarbinols or their acylates in 30 to 100% by weight of sulphuric acid, with optionally substituted hydrazine or its salts, in the presence of catalytic amounts of iodine or of an iodine compound.

公开(公告)号：DK0474037T3

公开(公告)日：1994-08-15

申请号：DK91114026

申请日：1991-08-22

Applicant: BASF AG

Inventor： MERKLE HANS RUPERT DR ,  FRETSCHNER ERICH

IPC: B01J27/06 ,  C07B61/00 ,  C07D231/12 ,  C07D521/00

Abstract: Production of 3-methylpyrazole and its derivatives by reacting butenediols or ethynylalkylcarbinols or their acylates in 30 to 100% by weight of sulphuric acid, with optionally substituted hydrazine or its salts, in the presence of catalytic amounts of iodine or of an iodine compound.

公开(公告)号：AT100799T

公开(公告)日：1994-02-15

申请号：AT90110517

申请日：1990-06-02

Applicant: BASF AG

Inventor： MERKLE HANS RUPERT DR ,  FRETSCHNER ERICH

IPC: C07D231/06 ,  C07D231/12

公开(公告)号：DE4028393A1

公开(公告)日：1992-03-12

申请号：DE4028393

申请日：1990-09-07

Applicant: BASF AG

Inventor： MERKLE HANS RUPERT DR ,  FRETSCHNER ERICH

IPC: B01J27/06 ,  C07B61/00 ,  C07D231/12 ,  C07D521/00

Abstract: Production of 3-methylpyrazole and its derivatives by reacting butenediols or ethynylalkylcarbinols or their acylates in 30 to 100% by weight of sulphuric acid, with optionally substituted hydrazine or its salts, in the presence of catalytic amounts of iodine or of an iodine compound.