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公开(公告)号：HRP20010484A2
公开(公告)日：2003-04-30
申请号：HRP20010484
申请日：2001-06-26
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOEGER THOMAS , SCHULT SABINE , GRANDEL ROLAND , MUELLER REINHOLD
IPC: A61K20060101 , A61K31/4184 , A61K31/454 , A61K31/496 , A61P20060101 , A61P3/12 , A61P9/00 , A61P9/10 , A61P13/12 , A61P17/02 , A61P25/00 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D20060101 , C07D235/30 , C07D401/04 , C07D401/14 , C07D403/04
Abstract: Compounds of the formula Ia or IB where A is a saturated or monounsaturated heterocyclic, 4 - to 8-membered ring which contains one or two nitrogen atoms, and their tautomeric forms, possible enantiomeric and diastereomeric forms, their prodrugs and possible physiologically tolerated salts are useful as inhibitors of the enzyme poly(ADP-ribose)polymerase.
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公开(公告)号：HU0200859A2
公开(公告)日：2002-11-28
申请号：HU0200859
申请日：2000-04-11
Applicant: BASF AG
Inventor： GRANDEL ROLAND , HOERGER THOMAS , KOCK MICHAEL , LUBISCH WILFRIED , MUELLER REINHOLD , SCHULT SABINE
IPC: C07D235/08 , A61K31/4184 , A61K31/4427 , A61K31/4523 , A61K31/496 , A61K31/551 , A61P3/10 , A61P9/00 , A61P9/10 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P35/04 , A61P43/00 , C07D235/10 , C07D235/12 , C07D235/14 , C07D235/16 , C07D401/08 , C07D403/08 , C07D235/06
Abstract: Compounds of the formula I or IIand their tautomeric forms, possible enantiomeric and diastereomeric forms, possible cistrans isomers on the rings in A and prodrugs thereof, pharmaceutical compositions containing these compounds and methods of treating neurodegenerative diseases or neuronal damage with these compounds.
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公开(公告)号：TR200103221T2
公开(公告)日：2002-04-22
申请号：TR200103221
申请日：2000-04-27
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOEGER THOMAS , GRANDEL ROLAND , HOLZENKAMP UTA , SCHULT SABINE , MUELLER REINHOLD
IPC: A61K31/415 , A61K31/4184 , A61K31/422 , A61K31/427 , A61K31/437 , A61K31/4439 , C07D235/20 , A61K31/4709 , A61K31/496 , A61K31/497 , A61P3/10 , A61P9/00 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/10 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D235/18 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D413/14 , C07D417/04 , C07D471/04
Abstract: The present invention relates to novel benzimidazoles, their preparation and their use as inhibitors of the enzyme poly(ADP-ribose) polymerase or PARP (EC 2.4.2.30) for producing drugs.
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公开(公告)号：PL347884A1
公开(公告)日：2002-04-22
申请号：PL34788499
申请日：1999-11-23
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOEGER THOMAS , SCHULT SABINE , GRANDEL ROLAND , MUELLER REINHOLD
IPC: A61K20060101 , A61K31/4184 , A61K31/454 , A61K31/496 , A61P20060101 , A61P3/12 , A61P9/00 , A61P9/10 , A61P13/12 , A61P17/02 , A61P25/00 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D20060101 , C07D235/30 , C07D401/04 , C07D401/14 , C07D403/04
Abstract: Compounds of the formula Ia or IB where A is a saturated or monounsaturated heterocyclic, 4 - to 8-membered ring which contains one or two nitrogen atoms, and their tautomeric forms, possible enantiomeric and diastereomeric forms, their prodrugs and possible physiologically tolerated salts are useful as inhibitors of the enzyme poly(ADP-ribose)polymerase.
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公开(公告)号：NO20021379A
公开(公告)日：2002-03-20
申请号：NO20021379
申请日：2002-03-20
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOEGER THOMAS , GRANDEL ROLAND , MUELLER REINHOLD , SCHULT SABINE
IPC: A61K31/5517 , A61P3/10 , A61P9/00 , A61P9/10 , A61P9/14 , A61P11/00 , A61P13/12 , A61P17/02 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/10 , A61P25/14 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P35/04 , A61P37/02 , A61P43/00 , C07D487/06 , C07D519/00 , C07D487/04
CPC classification number: C07D487/06
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Patent Agency Ranking
公开(公告)号：BR0009948A
公开(公告)日：2002-01-08
申请号：BR0009948
申请日：2000-04-11
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOEGER THOMAS , GRANDEL ROLAND , SCHULT SABINE , MUELLER REINHOLD
IPC: C07D235/08 , A61K31/4184 , A61K31/4427 , A61K31/4523 , A61K31/496 , A61K31/551 , A61P3/10 , A61P9/00 , A61P9/10 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P35/04 , A61P43/00 , C07D235/10 , C07D235/12 , C07D235/14 , C07D235/16 , C07D401/08 , C07D403/08 , C07D235/06
Abstract: Compounds of the formula I or IIand their tautomeric forms, possible enantiomeric and diastereomeric forms, possible cistrans isomers on the rings in A and prodrugs thereof, pharmaceutical compositions containing these compounds and methods of treating neurodegenerative diseases or neuronal damage with these compounds.
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公开(公告)号：NO20014963L
公开(公告)日：2001-11-13
申请号：NO20014963
申请日：2001-10-12
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOEGER THOMAS , GRANDEL ROLAND , SCHULT SABINE , MUELLER REINHOLD
IPC: C07D235/08 , A61K31/4184 , A61K31/4427 , A61K31/4523 , A61K31/496 , A61K31/551 , A61P3/10 , A61P9/00 , A61P9/10 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P35/04 , A61P43/00 , C07D235/10 , C07D235/12 , C07D235/14 , C07D235/16 , C07D401/08 , C07D403/08 , C07D235/06
Abstract: Compounds of the formula I or IIand their tautomeric forms, possible enantiomeric and diastereomeric forms, possible cistrans isomers on the rings in A and prodrugs thereof, pharmaceutical compositions containing these compounds and methods of treating neurodegenerative diseases or neuronal damage with these compounds.
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公开(公告)号：NO20015362L
公开(公告)日：2001-11-02
申请号：NO20015362
申请日：2001-11-02
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOEGER THOMAS , GRANDEL ROLAND , HOLZENKAMP UTA , SCHULT SABINE , MUELLER REINHOLD
IPC: A61K31/415 , C07D235/20 , A61K31/4184 , A61K31/422 , A61K31/427 , A61K31/437 , A61K31/4439 , A61K31/4709 , A61K31/496 , A61K31/497 , A61P3/10 , A61P9/00 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/10 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D235/18 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D413/14 , C07D417/04 , C07D471/04
Abstract: The present invention relates to novel benzimidazoles, their preparation and their use as inhibitors of the enzyme poly(ADP-ribose) polymerase or PARP (EC 2.4.2.30) for producing drugs.
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公开(公告)号：NO20012570D0
公开(公告)日：2001-05-25
申请号：NO20012570
申请日：2001-05-25
Applicant: BASF AG
Inventor： LUBISCH WILFRED , KOCK MICHAEL , HOEGER THOMAS , SCHULT SABINE , GRANDEL ROLAND , MUELLER REINHOLD
IPC: A61K20060101 , A61K31/4184 , A61K31/454 , A61K31/496 , A61P20060101 , A61P3/12 , A61P9/00 , A61P9/10 , A61P13/12 , A61P17/02 , A61P25/00 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D20060101 , C07D235/30 , C07D401/04 , C07D401/14 , C07D403/04 , C07D
Abstract: Compounds of the formula Ia or IB where A is a saturated or monounsaturated heterocyclic, 4 - to 8-membered ring which contains one or two nitrogen atoms, and their tautomeric forms, possible enantiomeric and diastereomeric forms, their prodrugs and possible physiologically tolerated salts are useful as inhibitors of the enzyme poly(ADP-ribose)polymerase.
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公开(公告)号：DE19920936A1
公开(公告)日：2000-11-09
申请号：DE19920936
申请日：1999-05-07
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOEGER THOMAS , GRANDEL ROLAND , MUELLER REINHOLD , SCHULT SABINE , HOLZENKAMP UTA
IPC: C07D235/20 , A61K31/415 , A61K31/4184 , A61K31/422 , A61K31/427 , A61K31/437 , A61K31/4439 , A61K31/4709 , A61K31/496 , A61K31/497 , A61P3/10 , A61P9/00 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/10 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D235/18 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D413/14 , C07D417/04 , C07D471/04
Abstract: The present invention relates to novel benzimidazoles, the production thereof and the utilisation as inhibitors of the enzyme poly(ADP-ribose)polymerase or PARP (EC 2.4.2.30) for producing medicaments.
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