公开(公告)号：DE59808037D1

公开(公告)日：2003-05-28

申请号：DE59808037

申请日：1998-10-14

Applicant: BASF AG

Inventor： GREINDL THOMAS DR ,  SCHERR GUENTER DR ,  SCHNEIDER ROLF DR ,  MUNDINGER KLAUS DR

IPC: C07C277/02 ,  C07C275/70 ,  C07C277/08 ,  C07C279/04 ,  C07C279/08 ,  C07C279/12 ,  C07C279/14 ,  C07C279/16 ,  C07C303/30 ,  C07C303/40 ,  C07C309/76 ,  C07C311/05 ,  C08G65/333 ,  C08G65/337 ,  C08G65/338 ,  C08G73/02

公开(公告)号：AT238276T

公开(公告)日：2003-05-15

申请号：AT98119421

申请日：1998-10-14

Applicant: BASF AG

Inventor： GREINDL THOMAS DR ,  SCHERR GUENTER DR ,  SCHNEIDER ROLF DR ,  MUNDINGER KLAUS DR

IPC: C07C277/02 ,  C07C273/18 ,  C07C275/70 ,  C07C277/08 ,  C07C279/04 ,  C07C279/14 ,  C07C303/22 ,  C07C303/30 ,  C07C309/15 ,  C07C309/69 ,  C07C311/47 ,  C08G65/333 ,  C08G73/02

Abstract: Preparation of guanidine derivatives comprises reacting calcium cyanamide with an alcohol to form an isourea derivative and reacting the isourea derivative with an amine. Preparation of guanidine derivatives of formula H2N-C(=NH)-N(R )(R ) (I) comprises (a) reacting calcium cyanamide with an alcohol of formula R OH to form an isourea derivative of formula H2N-C(=NH)-OR (II), and (b) reacting (II) with an amine of formula HN(R )(R ) (III), where R = H, 1-20C alkyl, 2-10C alkenyl or 3-8C cycloalkyl; R = 1-20C alkyl, 2-10C alkenyl, 3-8C cycloalkyl, ACOOR , ACONR R , ACN, ASO2R or Ä(CH2)mXÜpÄ(CH2)nYÜqÄ(CH2)oÜrZ; A = 1-20C alkylene; m, n and o = 0-10; p, q and r = 0-50000; X = O or NH; Y = NÄ(CH2)mXÜpÄ(CH2)nYÜqÄ(CH2)oÜrZ; Z = OH or NH2; R = H, 1-20C alkyl, 2-10C alkenyl, 3-8C cycloalkyl, 6-18C aryl, Na, K, Li, Ca, Mg or N(R )4; R , R = H, 1-20C alkyl, 2-10C alkenyl, 3-8C cycloalkyl or 6-18C aryl; R = OR or N(R )2; R = H or 1-20C alkyl; R = H, 1-20C alkyl, 2-10C alkenyl, 3-8C cycloalkyl, 6-18C aryl, Na, K, Li, Ca, Mg or N(R )4; R = H, 1-20C alkyl, 2-10C alkenyl, 3-8C cycloalkyl or 6-18C aryl; and R = 1-20C alkyl.

公开(公告)号：DE19748694A1

公开(公告)日：1999-05-06

申请号：DE19748694

申请日：1997-11-04

Applicant: BASF AG

Inventor： GREINDL THOMAS DR ,  SCHERR GUENTER DR ,  SCHNEIDER ROLF DR ,  MUNDINGER KLAUS DR

IPC: C07C277/02 ,  C07C273/18 ,  C07C275/70 ,  C07C277/08 ,  C07C279/04 ,  C07C279/14 ,  C07C303/22 ,  C07C303/30 ,  C07C309/15 ,  C07C309/69 ,  C07C311/47 ,  C08G65/333 ,  C08G73/02 ,  C07C279/08 ,  C07C279/12 ,  C07B43/00 ,  C08G65/26

Abstract: Preparation of guanidine derivatives comprises reacting calcium cyanamide with an alcohol to form an isourea derivative and reacting the isourea derivative with an amine. Preparation of guanidine derivatives of formula H2N-C(=NH)-N(R )(R ) (I) comprises (a) reacting calcium cyanamide with an alcohol of formula R OH to form an isourea derivative of formula H2N-C(=NH)-OR (II), and (b) reacting (II) with an amine of formula HN(R )(R ) (III), where R = H, 1-20C alkyl, 2-10C alkenyl or 3-8C cycloalkyl; R = 1-20C alkyl, 2-10C alkenyl, 3-8C cycloalkyl, ACOOR , ACONR R , ACN, ASO2R or Ä(CH2)mXÜpÄ(CH2)nYÜqÄ(CH2)oÜrZ; A = 1-20C alkylene; m, n and o = 0-10; p, q and r = 0-50000; X = O or NH; Y = NÄ(CH2)mXÜpÄ(CH2)nYÜqÄ(CH2)oÜrZ; Z = OH or NH2; R = H, 1-20C alkyl, 2-10C alkenyl, 3-8C cycloalkyl, 6-18C aryl, Na, K, Li, Ca, Mg or N(R )4; R , R = H, 1-20C alkyl, 2-10C alkenyl, 3-8C cycloalkyl or 6-18C aryl; R = OR or N(R )2; R = H or 1-20C alkyl; R = H, 1-20C alkyl, 2-10C alkenyl, 3-8C cycloalkyl, 6-18C aryl, Na, K, Li, Ca, Mg or N(R )4; R = H, 1-20C alkyl, 2-10C alkenyl, 3-8C cycloalkyl or 6-18C aryl; and R = 1-20C alkyl.

公开(公告)号：DE19637407A1

公开(公告)日：1998-03-19

申请号：DE19637407

申请日：1996-09-13

Applicant: BASF AG

Inventor： KRAMER ANDREAS DR ,  MUNDINGER KLAUS DR ,  BROECKER FRANZ JOSEF DR ,  SIEGEL WOLFGANG DR

IPC: C07D307/88

Abstract: The invention concerns a method for producing phthalides of general formula (I) in which phthalic acid anhydrides of general formula (II) are transformed on hydrogenation catalyzers at temperatures from 50 to 400 DEG C and pressures from 1 to 400 bar in such a way that the transformation is carried out in the liquid phase using phthalides of general formula (I) as solvent. In said formulae (I) and (II) R , R , R and R independently mean hydrogen, C1-4-alkyl or C1-4-alkoxy.