公开(公告)号：AT299505T

公开(公告)日：2005-07-15

申请号：AT99912660

申请日：1999-03-19

Applicant: BASF AG

Inventor： PFRENGLE WALDEMAR

IPC: A01N43/90 ,  C07D487/04 ,  C07D239/00 ,  C07D249/00

公开(公告)号：DE69913104T2

公开(公告)日：2004-06-17

申请号：DE69913104

申请日：1999-02-09

Applicant: BASF AG

Inventor： PFRENGLE WALDEMAR ,  PEES KLAUS-JUERGEN ,  ALBERT GUIDO

IPC: A01N43/00 ,  A01N43/90 ,  C07D487/04

Abstract: A process and intermediates for the preparation of triazolopyrimidine compounds of formula I wherein R , X, L , L , L , L and L are as defined in the description, which comprises reacting alkyl 2-aryl-3-alkyl-3-oxopropionates of formula IV wherein R and L , L , L , L and L are as defined for formula I and R' represents an optionally substituted alkyl group, a) with 2-amino-Ä1,3,4Ü-triazole, and treating the resulting 5-hydroxytriazolopyrimidines of formula I, wherein X represents a hydroxy group, with a halogenating agent, and b) optionally treating the resulting 5-hydroxytriazolopyrimidines with an alcohol or a thioalkohol in the presence of a base, or with a metal amide, a metal alkyl amide or a metal dialkylamide, or a metal cyanide.A process and intermediates for the preparation of triazolopyrimidine compounds of formula I wherein R , X, L , L , L , L and L are as defined in the description, which comprises reacting alkyl 2-aryl-3-alkyl-3-oxopropionates of formula IV wherein R and L , L , L , L and L are as defined for formula I and R' represents an optionally substituted alkyl group, a) with 2-amino-Ä1,3,4Ü-triazole, and treating the resulting 5-hydroxytriazolopyrimidines of formula I, wherein X represents a hydroxy group, with a halogenating agent, and b) optionally treating the resulting 5-hydroxytriazolopyrimidines with an alcohol or a thioalkohol in the presence of a base, or with a metal amide, a metal alkyl amide or a metal dialkylamide, or a metal cyanide.

公开(公告)号：SI1054888T1

公开(公告)日：2004-04-30

申请号：SI9930506

申请日：1999-02-09

Applicant: BASF AG

Inventor： PFRENGLE WALDEMAR ,  PEES KLAUS-JUERGEN ,  ALBERT GUIDO

IPC: A01N43/00 ,  C07D487/04 ,  A01N43/90

公开(公告)号：DK1054888T3

公开(公告)日：2004-04-05

申请号：DK99905905

申请日：1999-02-09

Applicant: BASF AG

Inventor： PFRENGLE WALDEMAR ,  PEES KLAUS-JUERGEN ,  ALBERT GUIDO

IPC: A01N43/00 ,  A01N43/90 ,  C07D487/04

Abstract: A process and intermediates for the preparation of triazolopyrimidine compounds of formula I wherein R , X, L , L , L , L and L are as defined in the description, which comprises reacting alkyl 2-aryl-3-alkyl-3-oxopropionates of formula IV wherein R and L , L , L , L and L are as defined for formula I and R' represents an optionally substituted alkyl group, a) with 2-amino-Ä1,3,4Ü-triazole, and treating the resulting 5-hydroxytriazolopyrimidines of formula I, wherein X represents a hydroxy group, with a halogenating agent, and b) optionally treating the resulting 5-hydroxytriazolopyrimidines with an alcohol or a thioalkohol in the presence of a base, or with a metal amide, a metal alkyl amide or a metal dialkylamide, or a metal cyanide.A process and intermediates for the preparation of triazolopyrimidine compounds of formula I wherein R , X, L , L , L , L and L are as defined in the description, which comprises reacting alkyl 2-aryl-3-alkyl-3-oxopropionates of formula IV wherein R and L , L , L , L and L are as defined for formula I and R' represents an optionally substituted alkyl group, a) with 2-amino-Ä1,3,4Ü-triazole, and treating the resulting 5-hydroxytriazolopyrimidines of formula I, wherein X represents a hydroxy group, with a halogenating agent, and b) optionally treating the resulting 5-hydroxytriazolopyrimidines with an alcohol or a thioalkohol in the presence of a base, or with a metal amide, a metal alkyl amide or a metal dialkylamide, or a metal cyanide.

公开(公告)号：DE69814375T2

公开(公告)日：2003-12-24

申请号：DE69814375

申请日：1998-03-23

Applicant: BASF AG

Inventor： PEES KLAUS-JUERGEN ,  KRUMMEL GUENTER ,  COTTER VAN ,  REHNIG ANNEROSE ,  MAY LESLIE ,  PFRENGLE WALDEMAR ,  ALBERT GUIDO

IPC: A01N43/90 ,  C07D487/04 ,  C07F7/08 ,  C07F7/12

Abstract: The novel compounds of formula (I), wherein R , R , Hal and L through L are defined in the specification, show selective fungicidal activity. The new compounds are processed with carriers and adjuvants to fungicidal compositions.

公开(公告)号：AT255110T

公开(公告)日：2003-12-15

申请号：AT99905905

申请日：1999-02-09

Applicant: BASF AG

Inventor： PFRENGLE WALDEMAR ,  PEES KLAUS-JUERGEN ,  ALBERT GUIDO

IPC: A01N43/00 ,  A01N43/90 ,  C07D487/04 ,  C07D249/00 ,  C07D239/00

Abstract: A process and intermediates for the preparation of triazolopyrimidine compounds of formula I wherein R , X, L , L , L , L and L are as defined in the description, which comprises reacting alkyl 2-aryl-3-alkyl-3-oxopropionates of formula IV wherein R and L , L , L , L and L are as defined for formula I and R' represents an optionally substituted alkyl group, a) with 2-amino-Ä1,3,4Ü-triazole, and treating the resulting 5-hydroxytriazolopyrimidines of formula I, wherein X represents a hydroxy group, with a halogenating agent, and b) optionally treating the resulting 5-hydroxytriazolopyrimidines with an alcohol or a thioalkohol in the presence of a base, or with a metal amide, a metal alkyl amide or a metal dialkylamide, or a metal cyanide.A process and intermediates for the preparation of triazolopyrimidine compounds of formula I wherein R , X, L , L , L , L and L are as defined in the description, which comprises reacting alkyl 2-aryl-3-alkyl-3-oxopropionates of formula IV wherein R and L , L , L , L and L are as defined for formula I and R' represents an optionally substituted alkyl group, a) with 2-amino-Ä1,3,4Ü-triazole, and treating the resulting 5-hydroxytriazolopyrimidines of formula I, wherein X represents a hydroxy group, with a halogenating agent, and b) optionally treating the resulting 5-hydroxytriazolopyrimidines with an alcohol or a thioalkohol in the presence of a base, or with a metal amide, a metal alkyl amide or a metal dialkylamide, or a metal cyanide.

公开(公告)号：DK0975635T3

公开(公告)日：2003-06-02

申请号：DK98914274

申请日：1998-03-23

Applicant: BASF AG

Inventor： PEES KLAUS-JUERGEN ,  KRUMMEL GUENTER ,  REHNIG ANNEROSE ,  PFRENGLE WALDEMAR ,  ALBERT GUIDO ,  COTTER HENRY VAN TUYL ,  MAY LESLIE

IPC: A01N43/90 ,  C07D487/04 ,  C07F7/08 ,  C07F7/12

Abstract: The novel compounds of formula (I), wherein R , R , Hal and L through L are defined in the specification, show selective fungicidal activity. The new compounds are processed with carriers and adjuvants to fungicidal compositions.

公开(公告)号：CA2412010A1

公开(公告)日：2001-12-20

申请号：CA2412010

申请日：2001-06-11

Applicant: BASF AG

Inventor： PEES KLAUS-JUERGEN ,  HEFFERNAN GAVIN ,  PFRENGLE WALDEMAR

IPC: C07D239/42 ,  A01N43/54 ,  A01N47/40 ,  A61K31/519 ,  C07D239/48 ,  C07D401/04 ,  C07D409/12 ,  C07D487/04

Abstract: Pyrimidines of formula (I) in which R1 represents hydrogen or alkyl, haloalkyl, alkenyl, alkynyl, alkadienyl, alkoxy, cycloalkyl, phenyl, or 5- o r 6-membered heteroaryl or 5- or 6-membered heterocyclyl, containing one to fo ur nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom, or tri-alkyl-silyl, formyl or alkoxycarbonyl, wherein R1 groups are unsubstituted or substituted as defined in the specification; R2 represents phenyl, cycloalkyl or 5- or 6-membered heteroaryl, containing one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom, which are unsubstituted or substituted; R3 represents hydrogen, halogen or alkyl, alkoxy, alkylthio, alkylamino or dialkylamino; which are unsubstitute d or substituted; R4 represents hydrogen or alkyl, alkenyl or alkynyl; which a re unsubstituted or substituted; and X represents O, S, NR5 or a single bond, wherein R5 represents hydrogen or alkyl; or R1 and R5 together with the interjacent nitrogen atom form a heterocyclic ring; processes and intermediates for preparing these compounds, to compositions comprising them and to their use for controlling harmful fungi.

公开(公告)号：AU778913B2

公开(公告)日：2004-12-23

申请号：AU7056401

申请日：2001-06-11

Applicant: BASF AG

Inventor： PEES KLAUS-JUERGEN ,  PFRENGLE WALDEMAR ,  HEFFERNAN GAVIN

IPC: C07D239/42 ,  A01N43/54 ,  A01N47/40 ,  A61K31/519 ,  C07D239/48 ,  C07D401/04 ,  C07D409/12 ,  C07D487/04

Abstract: Pyrimidines of formula I in which R 1 represents hydrogen or alkyl, haloalkyl, alkenyl, alkynyl, alkadienyl, alkoxy, cycloalkyl, phenyl, or 5- or 6-membered heteroaryl or 5- or 6-membered heterocyclyl, containing one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom, or tri-alkyl-silyl, formyl or alkoxy-carbonyl, wherein R 1 groups are unsubstituted or substituted as defined in the specification; R 2 represents phenyl, cycloalkyl or 5- or 6-membered heteroaryl, containing one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom, which are unsubstituted or substituted; R 3 represents hydrogen, halogen or alkyl, alkoxy, alkylthio, alkylamino or dialkylamino; which are unsubstituted or substituted; R 4 represents hydrogen or alkyl, alkenyl or alkynyl; which are unsubstituted or substituted; and X represents O, S, NR 5 or a single bond, wherein R 5 represents hydrogen or alkyl; or R 1 and R 5 together with the interjacent nitrogen atom form a heterocyclic ring; processes and intermediates for preparing these compounds, to compositions comprising them and to their use for controlling harmful fungi.

公开(公告)号：PT1054888E

公开(公告)日：2004-02-27

申请号：PT99905905

申请日：1999-02-09

Applicant: BASF AG

Inventor： PEES KLAUS-JURGEN ,  PFRENGLE WALDEMAR ,  ALBERT GUIDO

IPC: A01N43/00 ,  A01N43/90 ,  C07D487/04

Abstract: A process and intermediates for the preparation of triazolopyrimidine compounds of formula I wherein R , X, L , L , L , L and L are as defined in the description, which comprises reacting alkyl 2-aryl-3-alkyl-3-oxopropionates of formula IV wherein R and L , L , L , L and L are as defined for formula I and R' represents an optionally substituted alkyl group, a) with 2-amino-Ä1,3,4Ü-triazole, and treating the resulting 5-hydroxytriazolopyrimidines of formula I, wherein X represents a hydroxy group, with a halogenating agent, and b) optionally treating the resulting 5-hydroxytriazolopyrimidines with an alcohol or a thioalkohol in the presence of a base, or with a metal amide, a metal alkyl amide or a metal dialkylamide, or a metal cyanide.A process and intermediates for the preparation of triazolopyrimidine compounds of formula I wherein R , X, L , L , L , L and L are as defined in the description, which comprises reacting alkyl 2-aryl-3-alkyl-3-oxopropionates of formula IV wherein R and L , L , L , L and L are as defined for formula I and R' represents an optionally substituted alkyl group, a) with 2-amino-Ä1,3,4Ü-triazole, and treating the resulting 5-hydroxytriazolopyrimidines of formula I, wherein X represents a hydroxy group, with a halogenating agent, and b) optionally treating the resulting 5-hydroxytriazolopyrimidines with an alcohol or a thioalkohol in the presence of a base, or with a metal amide, a metal alkyl amide or a metal dialkylamide, or a metal cyanide.