公开(公告)号：US20160176805A1

公开(公告)日：2016-06-23

申请号：US14902890

申请日：2014-06-04

Applicant: BASF SE

Inventor： Timo FRASSETTO ,  Volker MAYWALD ,  Michael RACK ,  Maximilian DOCHNAHL ,  Bernd WOLF

IPC: C07C231/02 ,  C07C51/58

CPC classification number: C07C231/02 ,  C07C51/58 ,  C07C231/00 ,  C07C233/05 ,  C07C53/48

Abstract: The present invention relates to a process for manufacturing haloacetamides of formula (I), comprising sub-step (a): reacting halones of formula (II) with oleum; followed by sub-step (b): reacting the reaction mixture obtained in sub-step(a) with an amine of formula (IV) optionally in the presence of a base; wherein the variables are defined according to the description.

Abstract translation: 本发明涉及一种制备式（I）的卤代乙酰胺的方法，其包括以下步骤（a）：使式（II）的卤酮与发烟硫酸反应; 然后是亚步骤（b）：使在步骤（a）中获得的反应混合物与式（IV）的胺任选地在碱的存在下反应; 其中根据描述定义变量。

公开(公告)号：US20150216166A1

公开(公告)日：2015-08-06

申请号：US14684508

申请日：2015-04-13

Applicant: BASF SE

Inventor： Karsten KOERBER ,  Prashant DESHMUKH ,  Florian KAISER ,  Michael RACK ,  Timo FRASETTO ,  Gemma VEITCH ,  Markus KORDES ,  Marco NAUJOK

IPC: A01N43/56 ,  C07D401/04

CPC classification number: A01N43/56 ,  A01N37/28 ,  A01N41/12 ,  A01N43/50 ,  A01N43/80 ,  C07B2200/13 ,  C07C381/10 ,  C07D401/04 ,  C07D401/14 ,  C07D409/14 ,  C07D413/14

Abstract: The present invention relates to compounds of the formula (I) wherein R1 and R2 independently of one another are hydrogen, C1-C10-alkyl, C1-C10-haloalkyl, C3-C10-cycloalkyl, C3-C10-halocycloalkyl, C2-C10-alkenyl, C2-C10-haloalkenyl or together represent an aliphatic chain, or the like; R3 is halogen, cyano, C1-C8-alkyl, C1-C8-haloalkyl, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C2-C8-alkenyl, C2-C8-haloalkenyl, C1-C8-alkoxy, phenyl, or the like; R4 is hydrogen, C1-C10-alkyl, C1-C10-haloalkyl, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C2-C10-alkenyl, C2-C10-haloalkenyl, phenyl, or the like; t is 0 or 1; p is 0, 1, 2, 3 or 4. The present invention also relates to a process for preparing a compound of the formula (I) which comprises reacting a compound of the formula II with a compound of the formulae III or IV: where t, p, R1 R3, R3 and R4 are as defined in any of claims 1 to 6 and where A− is an equivalent of an anion having a pKB of at least 10 (determined under standard conditions in water).

Abstract translation: 本发明涉及式（I）化合物，其中R 1和R 2彼此独立地是氢，C 1 -C 10 - 烷基，C 1 -C 10 - 卤代烷基，C 3 -C 10 - 环烷基，C 3 -C 10 - 卤代环烷基，C 2 -C 10 烯基，C 2 -C 10 - 卤代链烯基或一起代表脂族链等; R3是卤素，氰基，C1-C8-烷基，C1-C8-卤代烷基，C3-C8-环烷基，C3-C8-卤代环烷基，C2-C8-烯基，C2-C8-卤代烯基，C1-C8-烷氧基，苯基， 或类似物; R4是氢，C1-C10-烷基，C1-C10-卤代烷基，C3-C8-环烷基，C3-C8-卤代环烷基，C2-C10-烯基，C2-C10-卤代烯基，苯基等; t为0或1; 本发明还涉及制备式（I）化合物的方法，其包括使式II化合物与式III或IV化合物反应：其中 t，p，R 1，R 3，R 3和R 4如权利要求1至6中任一项所定义，其中A-是pKB为至少10（在水中标准条件下测定）的阴离子的当量。