公开(公告)号：EP3119874B1

公开(公告)日：2019-05-08

申请号：EP15764058.2

申请日：2015-03-17

Applicant: CJ Cheiljedang Corporation

Inventor： KOH, Eun Sung ,  KWON, Su Yon ,  LEE, Kwang Ho ,  LEE, Ji Sun ,  JANG, Juno ,  LEE, Keun Cheol ,  HONG, Hyeong Pyo

IPC: C12N1/21 ,  C12N15/70 ,  C12P13/04

公开(公告)号：EP2405005B1

公开(公告)日：2018-09-19

申请号：EP10748903.1

申请日：2010-02-16

Applicant: CJ CheilJedang Corporation

Inventor： JU, Jae Yeong ,  LEE, Kwang Ho ,  BAE, Hyun Ae

IPC: C12N15/52 ,  C12N1/21 ,  C12P13/04 ,  C12R1/185

CPC classification number: C12P13/04 ,  C07K14/26 ,  C12N9/1205 ,  C12P13/08

Abstract: The present invention relates to a microorganism belonging to the genus Escherichia sp. and a. method for producing L-amino acid using the same. The microorganism belonging to the genus Escherichia sp. has a sucrose assimilability and L-amino acid producing ability, which is obtained by introducing a gene encoding a sucrose assimilative microorganism-derived sucrose metabolic enzyme to sucrose non-assimilative microorganism belonging to the genus Escherichia sp. having an L-amino acid producing ability and sucrose PTS (phosphoenolpyruvate dependent sucrose phosphotransferase system) activity.

公开(公告)号：EP3336191A1

公开(公告)日：2018-06-20

申请号：EP16792968.6

申请日：2016-05-10

Applicant: CJ Cheiljedang Corporation

Inventor： PARK, Hye Min ,  LEE, Baek Seok ,  LEE, Seok Myung ,  KIM, Kyungrim ,  LEE, Kwang Ho ,  CHEONG, Ki Yong ,  LEE, Keun Cheol ,  HONG, Hyeongpyo

IPC: C12N15/70 ,  C12P13/14

CPC classification number: C12P13/227 ,  C12N9/16 ,  C12N15/71 ,  C12Y301/03

Abstract: The present disclosure relates to a microorganism of the genus Escherichia producing more L-tryptophan by inactivating the activity of phosphatase.
Additionally, the present disclosure relates to a method for producing L-tryptophan using the microorganism of the genus Escherichia.

公开(公告)号：EP3119875A1

公开(公告)日：2017-01-25

申请号：EP15765883.2

申请日：2015-03-17

Applicant: CJ Cheiljedang Corporation

Inventor： LEE, Ji Sun ,  SEO, Chang Il ,  CHEONG, Ki Yong ,  KOH, Eun Sung ,  KWON, Do Hyun ,  LEE, Kwang Ho

IPC: C12N1/21 ,  C12N15/70 ,  C12P13/04

CPC classification number: C12N15/70 ,  C07K14/245 ,  C12N1/20 ,  C12P13/08 ,  C12P13/227

Abstract: Disclosed are a recombinant microorganism having enhanced L-amino acid producibility, wherein the recombinant microorganism is transformed to have an inactivated phage receptor thereof, and a method of producing an L-amino acid using the recombinant microorganism. The use of the recombinant microorganism may enable the production of the L-amino acid in a highly efficient manner.

Abstract translation: 本发明公开了具有增强的L-氨基酸生产性，worin重组微生物转化为具有灭活的噬菌体受体，以及它们的使用重组微生物生产L-氨基酸的方法的重组微生物。 使用该重组微生物的可以使生产L-氨基酸的以高度有效的方式。

公开(公告)号：EP3119874A1

公开(公告)日：2017-01-25

申请号：EP15764058.2

申请日：2015-03-17

Applicant: CJ Cheiljedang Corporation

Inventor： KOH, Eun Sung ,  KWON, Su Yon ,  LEE, Kwang Ho ,  LEE, Ji Sun ,  JANG, Juno ,  LEE, Keun Cheol ,  HONG, Hyeong Pyo

IPC: C12N1/21 ,  C12N15/70 ,  C12P13/04

CPC classification number: C12P13/227 ,  C12N9/2497 ,  C12N9/78 ,  C12P13/08 ,  C12Y302/02004 ,  C12Y305/04004

Abstract: Disclosed are a recombinant microorganism having enhanced L-amino acid productivity, wherein the recombinant microorganism is transformed to have removed or decreased activity of at least one of adenosine deaminase and AMP nucleosidase, and a method of producing an L-amino acid using the recombinant microorganism. The use of the recombinant microorganism may enable the production of the L-amino acid in a highly efficient manner.

Abstract translation: 本发明公开了具有增强的L-氨基酸生产力，worin重组微生物转化到已经移除或减少腺苷脱氨酶和AMP核苷中的至少一种的活性，并且使用所述重组微生物生产L-氨基酸的方法的重组微生物 ， 使用该重组微生物的可以使生产L-氨基酸的以高度有效的方式。

公开(公告)号：EP3078737A1

公开(公告)日：2016-10-12

申请号：EP14870476.0

申请日：2014-12-08

Applicant: CJ Cheiljedang Corporation

Inventor： MOON, Jun Ok ,  PARK, Sang Hee ,  HUH, Lan ,  LEE, Kwang Ho

IPC: C12N1/21 ,  C12N15/77 ,  C12P13/08 ,  C12R1/15

CPC classification number: C12N15/77 ,  C07K14/34 ,  C12P13/08 ,  C12R1/15

Abstract: Provided are a coryneform microorganism with improved ability to produce lysine in which septum formation initiator protein is inactivated, and a method for producing L-lysine using the microorganism.

Abstract translation: 提供与产生其中隔膜形成引发剂蛋白赖氨酸的能力提高失活，以及使用该微生物的L-赖氨酸的方法的棒状杆菌属微生物。

公开(公告)号：EP2233570B1

公开(公告)日：2015-03-18

申请号：EP09700769.4

申请日：2009-01-07

Applicant: CJ CheilJedang Corporation

Inventor： LEE, Kwang Ho ,  JU, Jae Yeong ,  LEE, Ji Sun ,  HWANG, Young Bin ,  JHON, Sung Hoo ,  KOH, Eun Sung ,  KIM, Chul Ha ,  SHIN, Soo An

IPC: C12N15/04 ,  C12N9/10 ,  C12N9/88 ,  C12P13/08

CPC classification number: C12P13/08 ,  C12N9/1085 ,  C12N9/88

公开(公告)号：EP2796555A2

公开(公告)日：2014-10-29

申请号：EP12859882.8

申请日：2012-12-21

Applicant: Cj Cheiljedang Corporation

Inventor： LEE, Kwang Ho ,  LIM, Sang Jo ,  MOON, Jun Ok ,  JANG, Jae Woo ,  PARK, Su Jin ,  PARK, Sang Hee

IPC: C12N15/52 ,  C12N15/63 ,  C12N15/74 ,  C12P13/08

CPC classification number: C12P13/08 ,  C12N9/1022 ,  C12N9/1217 ,  C12N9/93 ,  C12N15/52 ,  C12N15/63 ,  C12N15/74 ,  C12Y202/01001 ,  C12Y207/02004 ,  C12Y604/01001 ,  Y02P20/52

Abstract: The present invention relates to a modified polynucleotide encoding aspartate kinase (EC:2.7.2.4; hereinafter, referred to as LysC), transketolase (EC:2.2.1.1; hereinafter, referred to as Tkt) or pyruvate carboxylase (EC:6.4.1.1; hereinafter, referred to as Pyc), in which the initiation codon is substituted with ATG, a vector including the same, a microorganism transformed with the vector, and a method for producing L-lysine using the same.

Abstract translation: 本发明涉及一种修饰的多核苷酸编码的天冬氨酸激酶（EC：2.7.2.4;在后，由被称为型lysC），转酮醇酶（EC：2.2.1.1;在后，由被称为CLK）或丙酮酸羧化酶（EC：6.4.1.1 ;在后，由被称为比重计），其中，所述起始密码子取代有ATG，包括相同的载体，用该载体转化的微生物，以及使用相同的L-赖氨酸的方法。

公开(公告)号：EP2405005A9

公开(公告)日：2014-10-22

申请号：EP10748903.1

申请日：2010-02-16

Applicant: CJ CheilJedang Corporation

Inventor： JU, Jae Yeong ,  LEE, Kwang Ho ,  BAE, Hyun Ae

IPC: C12N15/52 ,  C12N1/21 ,  C12P13/04 ,  C12R1/185

CPC classification number: C12P13/04 ,  C07K14/26 ,  C12N9/1205 ,  C12P13/08

Abstract: The present invention relates to a microorganism belonging to the genus Escherichia sp. and a. method for producing L-amino acid using the same. The microorganism belonging to the genus Escherichia sp. has a sucrose assimilability and L-amino acid producing ability, which is obtained by introducing a gene encoding a sucrose assimilative microorganism-derived sucrose metabolic enzyme to sucrose non-assimilative microorganism belonging to the genus Escherichia sp. having an L-amino acid producing ability and sucrose PTS (phosphoenolpyruvate dependent sucrose phosphotransferase system) activity.

Abstract translation: 本发明涉及属于埃希氏菌属（Escherichia sp。）的微生物。 和a。 使用其制备L-氨基酸的方法。 属于埃希氏菌属的微生物 具有蔗糖同化性和L-氨基酸生产能力，其通过将编码蔗糖同化微生物来源的蔗糖代谢酶的基因导入属于埃希氏菌属的蔗糖非同化微生物而获得。 具有L-氨基酸生产能力和蔗糖PTS（磷酸烯醇丙酮酸依赖性蔗糖磷酸转移酶系统）活性。

公开(公告)号：EP2405005A2

公开(公告)日：2012-01-11

申请号：EP10748903.1

申请日：2010-02-16

Applicant: CJ CheilJedang Corporation

Inventor： JU, Jae Yeong ,  LEE, Kwang Ho ,  BAE, Hyun Ae

IPC: C12N15/52 ,  C12N1/21 ,  C12P13/04 ,  C12R1/185

CPC classification number: C12P13/04 ,  C07K14/26 ,  C12N9/1205 ,  C12P13/08

Abstract: The present invention relates to a microorganism belonging to the genus Escherichia sp. and a. method for producing L-amino acid using the same. The microorganism belonging to the genus Escherichia sp. has a sucrose assimilability and L-amino acid producing ability, which is obtained by introducing a gene encoding a sucrose assimilative microorganism-derived sucrose metabolic enzyme to sucrose non-assimilative microorganism belonging to the genus Escherichia sp. having an L-amino acid producing ability and sucrose PTS (phosphoenolpyruvate dependent sucrose phosphotransferase system) activity.

Abstract translation: 本发明涉及属于埃希氏杆菌属菌的微生物。 和。 制造方法使用相同的L-氨基酸。 属埃希氏菌属的微生物。 具有通过引入编码蔗糖同化微生物来源蔗糖代谢酶与蔗糖属于埃希氏菌属的属非同化微生物的基因而获得的蔗糖同化性和L-氨基酸产生能力，在所有。 具有L-氨基酸产生能力和蔗糖PTS（磷酸烯醇式丙酮酸依赖蔗糖磷酸转移酶系统）的活性。