公开(公告)号：US10894729B2

公开(公告)日：2021-01-19

申请号：US16095553

申请日：2017-04-20

Applicant: MISSISSIPPI INTERNATIONAL WATER INC. ,  AMAZON WATER INC. ,  Dawei Zhang

Inventor： Dawei Zhang

IPC: C02F11/12 ,  C02F1/52 ,  C02F9/00 ,  C02F101/10 ,  C02F101/16 ,  C02F1/28

Abstract: This disclosure discloses an apparatus of treating a river, comprising a river bed sludge suction device, a container-type sand-stone refuse separation device, a container-type dehydration device, a container-type pulverization device, a storage container, a container-type drying device, a container-type carbonization device, a container-type flocculation device, a container-type precipitation device, a container-type activated coke filtration and adsorption device, a container-type power generation device, a container-type operation and control chamber, and a cleaning ship for floating debris and river bank refuse. This disclosure discloses a method of treating a river using the apparatus described above where a biochar is produced from the separated, dehydrated and dried sludge. The biochar is then delivered back to the river bed to adsorb nitrogen and phosphorus, cleaning the river water, followed by purification treatments on sewage discharged from the dehydration apparatus and discharging the treated sewage water back to the river.

公开(公告)号：US10213817B2

公开(公告)日：2019-02-26

申请号：US15033563

申请日：2014-09-17

Applicant: Mississippi International Water Inc. ,  Amazon Environmental Protection Technology and Equipment PTE. Ltd. ,  Dawei Zhang

Inventor： Dawei Zhang

IPC: C10B1/00 ,  B09B3/00 ,  C05F1/00 ,  C05F1/02 ,  F23G5/027 ,  C02F1/28 ,  C10B7/10 ,  C10B41/00 ,  C10B53/00 ,  C10B57/00 ,  C05F9/00

Abstract: Disclosed is a method for anaerobic pyrolysis treatment of dead-of-disease livestock and municipal organic refuse, which uses an anaerobic pyrolysis device to perform a harmlessness treatment on dead-of-disease pigs, the treatment being a chemical reaction process performed in a sealed, oxygen-free, non-combustible, high-temperature state, comprising heating the bodies of pigs to a high temperature under an anaerobic state, and by the action of thermal decomposition through reactions such as vaporization, pyrolysis, dehydrogenation, thermal condensation and carbonization, evaporating the moisture from the pig bodies, converting the organics therein to combustible gases and organic carbon, and killing various types of bacteria in the bodies of the dead pigs via the high temperature. Thus, a harmlessness and reutilization treatment of the dead-of-disease livestock is achieved, and environmental pollution and propagation of fatal animal diseases, such as foot-and-mouth disease, highly pathogenic avian influenza, highly pathogenic blue-ear pig disease and swine fever are avoided. Also disclosed is a device for realizing the above-mentioned method.

公开(公告)号：US08964589B2

公开(公告)日：2015-02-24

申请号：US13704119

申请日：2011-06-27

Applicant: Nan Li ,  Zhenping Hu ,  Dawei Zhang ,  Jin Xu

Inventor： Nan Li ,  Zhenping Hu ,  Dawei Zhang ,  Jin Xu

IPC: H04J1/16 ,  H04W4/00

CPC classification number: H04W72/044 ,  H04W48/12

Abstract: A method and device for obtaining carrier information and carrier information indication include: a user equipment obtains parameters of uplink carrier information according to the message sent by a network side in broadcast manner, or, the user equipment obtains parameters of uplink carrier information according to the preset information. Time Division Duplex wireless communication system with asymmetry uplink frequency band and downlink frequency band can be supported effectively, guard frequency band near the intersection occurred when the adjacent frequencies coexist is utilized fully, and frequency spectrum utilization rate is improved; further more, Time Division Duplex wireless communication system with unequal uplink band width and downlink band width can be supported, and the application of the Time Division Duplex system is expanded effectively.

Abstract translation: 一种用于获取载波信息和载波信息指示的方法和装置，包括：用户设备根据网络侧以广播方式发送的消息获取上行链路载波信息的参数，或者根据用户设备获取上行链路载波信息的参数 预设信息。 时分双工无线通信系统具有不对称的上行频带和下行频带，可以有效支持邻近频段共存的邻近保护频带，频谱利用率提高; 可以支持上行带宽和下行带宽不等的时分双工无线通信系统，有效扩展时分双工系统的应用。

公开(公告)号：US20130094409A1

公开(公告)日：2013-04-18

申请号：US13704119

申请日：2011-06-27

Applicant: Nan Li ,  Zhenping Hu ,  Dawei Zhang ,  Jin Xu

Inventor： Nan Li ,  Zhenping Hu ,  Dawei Zhang ,  Jin Xu

IPC: H04W72/04

CPC classification number: H04W72/044 ,  H04W48/12

Abstract: A method and device for obtaining carrier information and carrier information indication include: a user equipment obtains parameters of uplink carrier information according to the message sent by a network side in broadcast manner, or, the user equipment obtains parameters of uplink carrier information according to the preset information. Time Division Duplex wireless communication system with asymmetry uplink frequency band and downlink frequency band can be supported effectively, guard frequency band near the intersection occurred when the adjacent frequencies coexist is utilized fully, and frequency spectrum utilization rate is improved; further more, Time Division Duplex wireless communication system with unequal uplink band width and downlink band width can be supported, and the application of the Time Division Duplex system is expanded effectively.

Abstract translation: 一种用于获取载波信息和载波信息指示的方法和装置，包括：用户设备根据网络侧以广播方式发送的消息获取上行链路载波信息的参数，或者根据用户设备获取上行链路载波信息的参数 预设信息。 时分双工无线通信系统具有不对称的上行频带和下行频带，可以有效支持邻近频段共存的邻近保护频带，频谱利用率提高; 可以支持上行带宽和下行带宽不等的时分双工无线通信系统，有效扩展时分双工系统的应用。

公开(公告)号：US08388902B2

公开(公告)日：2013-03-05

申请号：US12809557

申请日：2008-12-16

Applicant: Dawei Zhang

Inventor： Dawei Zhang

IPC: C01B31/08 ,  B01J38/06 ,  B01J8/10

CPC classification number: B01J20/20 ,  B01J20/3416 ,  B01J20/3466 ,  B01J20/3483 ,  C01B32/366 ,  C02F1/283 ,  C02F2303/16 ,  Y02C10/08

Abstract: A method for regenerating activated coke used for treating wastewater or sewage is provided. The method includes loading the activated coke to an environment under 150 to 250° C., heating the activated coke to a temperature of 700 to 850° C. for about 40 to 90 minutes; and providing a steam to the activated coke with a rate of 0.1 to 0.5 m3/(ton of activated coke). When the activated coke is being heated at the temperature, it generates a gas mixture including a steam portion and at least a paraffine gas. The gas mixture flows along a reverse direction relative to a flow of cooling water, so that the steam portion is converted into a part of the cooling water for recycling. The paraffine gas is used as a fuel. An apparatus for regenerating the activated coke used for treating wastewater or sewage is also provided.

Abstract translation: 提供了一种再生用于处理废水或污水的活性焦炭的方法。 该方法包括将活化的焦炭装载到150至250℃的环境中，将活化的焦炭加热至700至850℃的温度约40至90分钟; 并以0.1至0.5m 3 /（tt活性焦炭）的速率向活化焦炭提供蒸汽。 当活化焦炭在该温度下被加热时，其产生包括蒸汽部分和至少一种石蜡气体的气体混合物。 气体混合物相对于冷却水的流动沿相反方向流动，使得蒸汽部分被转化成冷却水的一部分以便再循环。 石蜡气被用作燃料。 还提供了用于再生用于处理废水或污水的活性焦炭的装置。

公开(公告)号：US08183259B2

公开(公告)日：2012-05-22

申请号：US13187154

申请日：2011-07-20

Applicant: Yi Chen ,  Timothy D. Cushing ,  Xiaolin Hao ,  Xiao He ,  Andreas Reichelt ,  Robert M. Rzasa ,  Jennifer Seganish ,  Youngsook Shin ,  Dawei Zhang

Inventor： Yi Chen ,  Timothy D. Cushing ,  Xiaolin Hao ,  Xiao He ,  Andreas Reichelt ,  Robert M. Rzasa ,  Jennifer Seganish ,  Youngsook Shin ,  Dawei Zhang

IPC: A61K31/47

CPC classification number: C07D401/12 ,  C07D401/14

Abstract: Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110δ activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia (T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.

Abstract translation: 取代的双环杂芳基和含有它们的组合物，用于治疗一般炎症，关节炎，风湿性疾病，骨关节炎，炎性肠病，炎症性眼病，炎症性或不稳定性膀胱病，牛皮癣，皮肤炎症成分的投诉，慢性炎性病症 不限于自身免疫疾病如系统性红斑狼疮（SLE），重症肌无力，类风湿性关节炎，急性播散性脑脊髓炎，特发性血小板减少性紫癜，多发性硬化症，Sjoegren综合征和自身免疫性溶血性贫血，包括所有形式的超敏反应的过敏症状 包括但不限于白血病，如急性骨髓性白血病（AML）骨髓增生异常综合征（MDS）骨髓增生性疾病（MPD）慢性骨髓性白血病（MPD），介导，依赖或与p110δ活性相关的癌症的方法 （CML）T细胞急性淋巴细胞白血病（T-ALL）B细胞急性淋巴细胞白血病（B-ALL）非霍奇金淋巴瘤（NHL）B细胞淋巴瘤和实体瘤如乳腺癌。

公开(公告)号：US08183258B2

公开(公告)日：2012-05-22

申请号：US13187135

申请日：2011-07-20

Applicant: Yi Chen ,  Timothy D. Cushing ,  Xiaolin Hao ,  Xiao He ,  Andreas Reichelt ,  Robert M. Rzasa ,  Jennifer Seganish ,  Youngsook Shin ,  Dawei Zhang

Inventor： Yi Chen ,  Timothy D. Cushing ,  Xiaolin Hao ,  Xiao He ,  Andreas Reichelt ,  Robert M. Rzasa ,  Jennifer Seganish ,  Youngsook Shin ,  Dawei Zhang

IPC: A61K31/47

CPC classification number: C07D401/12 ,  C07D401/14

Abstract: Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity. The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110δ activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia (T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.

Abstract translation: 取代的双环杂芳基和含有它们的组合物，用于治疗一般炎症，关节炎，风湿性疾病，骨关节炎，炎性肠病，炎症性眼病，炎症性或不稳定性膀胱病，牛皮癣，皮肤炎症成分的投诉，慢性炎性病症 不限于自身免疫性疾病如系统性红斑狼疮（SLE），重症肌无力，类风湿关节炎，急性播散性脑脊髓炎，特发性血小板减少性紫癜，多发性硬化症，Sjoegren综合征和自身免疫性溶血性贫血，包括所有形式的超敏反应的过敏症状。 本发明还使得能够治疗依赖于p110δ活性或与p110δ活性相关的癌症的方法，包括但不限于白血病，例如急性骨髓性白血病（AML）Myelo-dysplastic综合征（MDS）骨髓增殖性疾病（MPD） 慢性骨髓性白血病（CML）T细胞急性淋巴细胞白血病（T-ALL）B细胞急性淋巴细胞白血病（B-ALL）非霍奇金淋巴瘤（NHL）B细胞淋巴瘤和实体瘤如乳腺癌。

公开(公告)号：US20120040983A1

公开(公告)日：2012-02-16

申请号：US13123889

申请日：2009-10-07

Applicant: Andrew Tasker ,  James R. Falsey ,  Robert M. Rzasa ,  Bradley J. Herberich ,  Dawei Zhang

Inventor： Andrew Tasker ,  James R. Falsey ,  Robert M. Rzasa ,  Bradley J. Herberich ,  Dawei Zhang

IPC: C07D401/04 ,  A61K31/50 ,  C07D413/02 ,  A61P25/28 ,  A61P3/10 ,  A61P11/06 ,  A61P31/12 ,  A61P1/04 ,  A61P19/02 ,  A61P11/00 ,  A61P9/10 ,  A61P31/18 ,  A61P25/00 ,  A61P37/08 ,  A61P17/00 ,  A61P19/00 ,  A61P31/22 ,  A61P17/06 ,  A61K31/501

CPC classification number: C07D401/12 ,  C07D237/30 ,  C07D237/32 ,  C07D237/34 ,  C07D401/04 ,  C07D403/04 ,  C07D413/04

Abstract: The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including inflammation and related conditions. The compounds have a general Formula I wherein A4, L, R1, R2, R3, R5 and m are as defined herein. The invention also comprises pharmaceutical compositions including one or more compounds of Formula I, uses of such compounds and compositions for treatment of p38 map kinase mediated diseases including rheumatoid arthritis, psoriasis, chronic obstructive pulmonary disease, ankylosing spondylitis, pain and other inflammatory disorders, as well as intermediates and processes useful for the preparation of compounds of Formula I.

Abstract translation: 本发明包括一类新的可用于预防和治疗蛋白激酶介导的疾病，包括炎症和相关病症的化合物。 该化合物具有通式I，其中A4，L，R1，R2，R3，R5和m如本文所定义。 本发明还包括药物组合物，其包含一种或多种式I化合物，用于治疗p38地图激酶介导的疾病包括类风湿性关节炎，牛皮癣，慢性阻塞性肺病，强直性脊柱炎，疼痛和其它炎症性疾病的化合物和组合物的用途，如 以及可用于制备式I化合物的中间体和方法。

公开(公告)号：US20110275653A1

公开(公告)日：2011-11-10

申请号：US13187154

申请日：2011-07-20

Applicant: Yi Chen ,  Timothy D. Cushing ,  Xiaolin Hao ,  Xiao He ,  Andreas Reichelt ,  Robert M. Rzasa ,  Jennifer Seganish ,  Youngsook Shin ,  Dawei Zhang

Inventor： Yi Chen ,  Timothy D. Cushing ,  Xiaolin Hao ,  Xiao He ,  Andreas Reichelt ,  Robert M. Rzasa ,  Jennifer Seganish ,  Youngsook Shin ,  Dawei Zhang

IPC: A61K31/506 ,  A61P35/02 ,  A61P35/00

CPC classification number: C07D401/12 ,  C07D401/14

Abstract: Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110δ activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia (T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.

公开(公告)号：US20110142973A1

公开(公告)日：2011-06-16

申请号：US12932018

申请日：2011-02-16

Applicant: Sylvia Lee-Huang ,  Paul L. Huang ,  Philip Lin Huang ,  Dawei Zhang ,  John Z.H. Zhang ,  Young Tae Chang ,  Jae Wook Lee ,  Ju Bao ,  Yongtao Sun

Inventor： Sylvia Lee-Huang ,  Paul L. Huang ,  Philip Lin Huang ,  Dawei Zhang ,  John Z.H. Zhang ,  Young Tae Chang ,  Jae Wook Lee ,  Ju Bao ,  Yongtao Sun

IPC: A61K36/63 ,  A61P3/00

CPC classification number: A61K31/7048 ,  A61K31/05 ,  A61K31/155 ,  A61K31/175 ,  A61K31/351 ,  A61K31/366 ,  A61K31/40 ,  A61K31/404 ,  A61K31/427 ,  A61K31/435 ,  A61K31/4439 ,  A61K31/445 ,  A61K31/70 ,  A61K31/7036 ,  A61K36/00 ,  A61K38/28 ,  A61K45/06

Abstract: The present invention relates to methods and pharmaceutical compositions for treating obesity or obesity-related disorders in a subject suffering from or predisposed to developing obesity or an obesity-related disorder, or for inhibiting the infectivity of HIV, by administering oleuropein, an analogue or derivative thereof, or the major metabolites of oleuropein including oleuropein aglycone, hydroxytyrosol, and elenolic acid or their analogues, or derivatives thereof, an iridoid glycoside, or a secoiridoid glycoside or analogues or derivatives thereof, or any combination of the foregoing including olive leave extract. The invention also relates to methods for screening/diagnosing a subject having, or predisposed to having obesity or a related disorder by measuring the expression profiles of an adipogenic gene selected from PPARγ2, LPL and αP2 gene and gene product, or other adipogenic, lipogenic, or lipolytic genes and gene products in an individual. The invention further provides for screening for novel oleuropein analogues.

Abstract translation: 本发明涉及通过给予橄榄苷，类似物或衍生物来治疗患有或倾向于发生肥胖或肥胖相关病症或抑制HIV感染性的受试者中的肥胖或肥胖相关疾病的方法和药物组合物 或橄榄苦蛋白的主要代谢物，包括橄榄苷苷苷元，羟基酪醇和烯诺酸或其类似物或衍生物，环烯醚萜苷，或其类似物或衍生物，或上述物质的任何组合，包括橄榄果提取物。 本发明还涉及通过测量选自PPARγ2，LPL和αP2基因的脂肪形成基因和基因产物或其它脂肪生成，脂质生成的脂肪形成基因的表达谱来筛选/诊断具有或倾向于具有肥胖症或相关病症的受试者的方法， 或脂肪分解基因和基因产物。 本发明进一步提供了新的橄榄苦苷类似物的筛选。